Works by Darcy, Phillip K.


Results: 59
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    Generating CAR T cells from tumor-infiltrating lymphocytes.

    Published in:
    Therapeutic Advances in Vaccines & Immunotherapy, 2021, v. 9, n. 50, p. 1, doi. 10.1177/25151355211017119
    By:
    • Mills, Jane K.;
    • Henderson, Melissa A.;
    • Giuffrida, Lauren;
    • Petrone, Pasquale;
    • Westwood, Jennifer A.;
    • Darcy, Phillip K.;
    • Neeson, Paul J.;
    • Kershaw, Michael H.;
    • Gyorki, David E.
    Publication type:
    Article
    3

    CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23331-5
    By:
    • Giuffrida, Lauren;
    • Sek, Kevin;
    • Henderson, Melissa A.;
    • Lai, Junyun;
    • Chen, Amanda X. Y.;
    • Meyran, Deborah;
    • Todd, Kirsten L.;
    • Petley, Emma V.;
    • Mardiana, Sherly;
    • Mølck, Christina;
    • Stewart, Gregory D.;
    • Solomon, Benjamin J.;
    • Parish, Ian A.;
    • Neeson, Paul J.;
    • Harrison, Simon J.;
    • Kats, Lev M.;
    • House, Imran G.;
    • Darcy, Phillip K.;
    • Beavis, Paul A.
    Publication type:
    Article
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    CAR T-cell therapy of solid tumors.

    Published in:
    Immunology & Cell Biology, 2017, v. 95, n. 4, p. 356, doi. 10.1038/icb.2016.128
    By:
    • Yong, Carmen S M;
    • Dardalhon, Valerie;
    • Devaud, Christel;
    • Taylor, Naomi;
    • Darcy, Phillip K;
    • Kershaw, Michael H
    Publication type:
    Article
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    Estrogen-induced immune changes within the normal mammary gland.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-21871-4
    By:
    • Tower, Helen;
    • Dall, Genevieve;
    • Davey, Ashleigh;
    • Stewart, Melanie;
    • Lanteri, Patrick;
    • Ruppert, Meagan;
    • Lambouras, Maria;
    • Nasir, Ibraheem;
    • Yeow, Serene;
    • Darcy, Phillip K.;
    • Ingman, Wendy V.;
    • Parker, Belinda;
    • Haynes, Nicole M.;
    • Britt, Kara L.
    Publication type:
    Article
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    Combined PARP and WEE1 inhibition triggers anti-tumor immune response in BRCA1/2 wildtype triple-negative breast cancer.

    Published in:
    NPJ Breast Cancer, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41523-023-00568-5
    By:
    • Teo, Zhi Ling;
    • O'Connor, Mark J.;
    • Versaci, Stephanie;
    • Clarke, Kylie A.;
    • Brown, Emmaline R.;
    • Percy, Luke W.;
    • Kuykhoven, Keilly;
    • Mintoff, Christopher P.;
    • Savas, Peter;
    • Virassamy, Balaji;
    • Luen, Stephen J.;
    • Byrne, Ann;
    • Sant, Sneha;
    • Lindeman, Geoffrey J.;
    • Darcy, Phillip K.;
    • Loi, Sherene
    Publication type:
    Article
    16

    Tucatinib promotes immune activation and synergizes with programmed cell death–1 and programmed cell death–ligand 1 inhibition in HER2-positive breast cancer.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 7, p. 805, doi. 10.1093/jnci/djad072
    By:
    • Li, Ran;
    • Sant, Sneha;
    • Brown, Emmaline;
    • Caramia, Franco;
    • Nikolic, Bronte;
    • Clarke, Kylie;
    • Byrne, Ann;
    • Gonzalez, Luis E Lara;
    • Savas, Peter;
    • Luen, Stephen J;
    • Teo, Zhi Ling;
    • Virassamy, Balaji;
    • Neeson, Paul J;
    • Darcy, Phillip K;
    • Loi, Sherene
    Publication type:
    Article
    17

    Novel combination immunotherapy for pancreatic cancer: potent anti‐tumor effects with CD40 agonist and interleukin‐15 treatment.

    Published in:
    Clinical & Translational Immunology, 2020, v. 9, n. 8, p. 1, doi. 10.1002/cti2.1165
    By:
    • Van Audenaerde, Jonas RM;
    • Marcq, Elly;
    • Scheidt, Bianca;
    • Davey, Ashleigh S;
    • Oliver, Amanda J;
    • De Waele, Jorrit;
    • Quatannens, Delphine;
    • Van Loenhout, Jinthe;
    • Pauwels, Patrick;
    • Roeyen, Geert;
    • Lardon, Filip;
    • Slaney, Clare Y;
    • Peeters, Marc;
    • Kershaw, Michael H;
    • Darcy, Phillip K;
    • Smits, Evelien LJM
    Publication type:
    Article
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    Tissue‐specific tumor microenvironments influence responses to immunotherapies.

    Published in:
    Clinical & Translational Immunology, 2019, v. 8, n. 11, p. 1, doi. 10.1002/cti2.1094
    By:
    • Oliver, Amanda J;
    • Davey, Ashleigh S;
    • Keam, Simon P;
    • Mardiana, Sherly;
    • Chan, Jack D;
    • Scheidt, Bianca;
    • Beavis, Paul A;
    • House, Imran G;
    • Van Audernaerde, Jonas RM;
    • Darcy, Phillip K;
    • Kershaw, Michael H;
    • Slaney, Clare Y
    Publication type:
    Article
    20

    CAR T cells take centre stage.

    Published in:
    Clinical & Translational Immunology, 2019, v. 8, n. 7, p. N.PAG, doi. 10.1002/cti2.1068
    By:
    • Beavis, Paul A;
    • Darcy, Phillip K
    Publication type:
    Article
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    CAR-T cells are serial killers.

    Published in:
    OncoImmunology, 2015, v. 4, n. 12, p. N.PAG, doi. 10.1080/2162402X.2015.1053684
    By:
    • Davenport, Alexander J;
    • Jenkins, Misty R;
    • Ritchie, David S;
    • Prince, H Miles;
    • Trapani, Joseph A;
    • Kershaw, Michael H;
    • Darcy, Phillip K;
    • Neeson, Paul J
    Publication type:
    Article
    24

    CD73: A potential biomarker for anti-PD-1 therapy.

    Published in:
    OncoImmunology, 2015, v. 4, n. 11, p. 1046675-1, doi. 10.1080/2162402X.2015.1046675
    By:
    • Beavis, Paul A.;
    • Slaney, Clare Y.;
    • Milenkovski, Nicole;
    • Henderson, Melissa A.;
    • Loi, Sherene;
    • Stagg, John;
    • Kershaw, Michael H.;
    • Darcy, Phillip K.
    Publication type:
    Article
    25

    Cross-talk between tumors can affect responses to therapy.

    Published in:
    OncoImmunology, 2015, v. 4, n. 7, p. N.PAG, doi. 10.4161/2162402X.2014.975572
    By:
    • Devaud, Christel;
    • John, Liza B;
    • Westwood, Jennifer A;
    • Yong, Carmen SM;
    • Beavis, Paul A;
    • Schwendener, Reto A;
    • Darcy, Phillip K;
    • Kershaw, Michael H
    Publication type:
    Article
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    Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 393, p. 1, doi. 10.1126/scitranslmed.aal4922
    By:
    • Nolan, Emma;
    • Savas, Peter;
    • Policheni, Antonia N.;
    • Darcy, Phillip K.;
    • Vaillant, François;
    • Mintoff, Christopher P.;
    • Dushyanthen, Sathana;
    • Mansour, Mariam;
    • Pang, Jia-Min B.;
    • Fox, Stephen B.;
    • Perou, Charles M.;
    • Visvader, Jane E.;
    • Gray, Daniel H. D.;
    • Loi, Sherene;
    • Lindeman, Geoffrey J.
    Publication type:
    Article
    33

    PTPN2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours.

    Published in:
    EMBO Journal, 2020, v. 39, n. 2, p. N.PAG, doi. 10.15252/embj.2019103637
    By:
    • Wiede, Florian;
    • Lu, Kun‐Hui;
    • Du, Xin;
    • Liang, Shuwei;
    • Hochheiser, Katharina;
    • Dodd, Garron T;
    • Goh, Pei K;
    • Kearney, Conor;
    • Meyran, Deborah;
    • Beavis, Paul A;
    • Henderson, Melissa A;
    • Park, Simone L;
    • Waithman, Jason;
    • Zhang, Sheng;
    • Zhang, Zhong‐Yin;
    • Oliaro, Jane;
    • Gebhardt, Thomas;
    • Darcy, Phillip K;
    • Tiganis, Tony
    Publication type:
    Article
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    Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia.

    Published in:
    Molecular Therapy, 2013, v. 21, n. 11, p. 2122, doi. 10.1038/mt.2013.154
    By:
    • Ritchie, David S.;
    • Neeson, Paul J.;
    • Khot, Amit;
    • Peinert, Stefan;
    • Tai, Tsin;
    • Tainton, Kellie;
    • Chen, Karen;
    • Shin, Mandy;
    • Wall, Dominic M.;
    • Hönemann, Dirk;
    • Gambell, Peter;
    • Westerman, David A.;
    • Haurat, Javier;
    • Westwood, Jennifer A.;
    • Scott, Andrew M.;
    • Kravets, Lucy;
    • Dickinson, Michael;
    • Trapani, Joseph A.;
    • Smyth, Mark J.;
    • Darcy, Phillip K.
    Publication type:
    Article
    40

    Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer.

    Published in:
    Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00728-9
    By:
    • Dushyanthen, Sathana;
    • Zhi Ling Teo;
    • Caramia, Franco;
    • Savas, Peter;
    • Mintoff, Christopher P.;
    • Virassamy, Balaji;
    • Henderson, Melissa A.;
    • Luen, Stephen J.;
    • Mansour, Mariam;
    • Kershaw, Michael H.;
    • Trapani, Joseph A.;
    • Neeson, Paul J.;
    • Salgado, Roberto;
    • McArthur, Grant A.;
    • Balko, Justin M.;
    • Beavis, Paul A.;
    • Darcy, Phillip K.;
    • Loi, Sherene
    Publication type:
    Article
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    Foxp3 Expression in Macrophages Associated with RENCA Tumors in Mice.

    Published in:
    PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108670
    By:
    • Devaud, Christel;
    • Yong, Carmen S. M.;
    • John, Liza B.;
    • Westwood, Jennifer A.;
    • Duong, Connie P. M.;
    • House, Colin M.;
    • Denoyer, Delphine;
    • Li, Jason;
    • Darcy, Phillip K.;
    • Kershaw, Michael H.
    Publication type:
    Article
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    Differential location of NKT and MAIT cells within lymphoid tissue.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07704-4
    By:
    • Johnson, Darryl N.;
    • Ruan, Zheng;
    • Petley, Emma V.;
    • Devi, Sapna;
    • Holz, Lauren E.;
    • Uldrich, Adam P.;
    • Mak, Jeffrey Y. W.;
    • Hor, Jyh Liang;
    • Mueller, Scott N.;
    • McCluskey, James;
    • Fairlie, David P.;
    • Darcy, Phillip K.;
    • Beavis, Paul A.;
    • Heath, William R.;
    • Godfrey, Dale I.
    Publication type:
    Article