Works matching AU Darcy, Justin

Results: 15

An Investigational RNAi Therapeutic for Tau Lowering.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.074204

By:

Farley, Jonathan;
Haines, Jeffery D;
Gannon, Sean;
Nguyen, Tuyen;
Abbott, Stephen;
Darcy, Justin;
Tymon, Roxanne;
Cha, Diana;
Schlegel, Mark;
Castoreno, Adam;
Bisbe, Anna;
Zlatev, Ivan;
Rollins, Jeff;
Bostwick, Bret;
Avbersek, Andreja;
Macdonald, Lynn;
Gao, Min;
Anderson, Matthew;
Brown, Kirk

Publication type:

Article

Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1203534

By:

Kanako Iwasaki;
Lalani, Benjamin;
Jiho Kahng;
Carapeto, Priscila;
Sanjines, Stephanie;
Hela, Francesko;
Abarca, Cristian;
Tadataka Tsuji;
Darcy, Justin;
Bartke, Andrzej;
Yu-Hua Tseng;
Kulkarni, Rohit N.;
Aguayo-Mazzucato, Cristina

Publication type:

Article

Altered structure and function of adipose tissue in long-lived mice with growth hormone-related mutations.

Published in:

Adipocyte, 2017, v. 6, n. 2, p. 69, doi. 10.1080/21623945.2017.1308990

By:

Darcy, Justin;
McFadden, Samuel;
Bartke, Andrzej

Publication type:

Article

Functionally enhanced brown adipose tissue in Ames dwarf mice.

Published in:

Adipocyte, 2017, v. 6, n. 1, p. 62, doi. 10.1080/21623945.2016.1274470

By:

Darcy, Justin;
Bartke, Andrzej

Publication type:

Article

Original Research: Metabolic alterations from early life thyroxine replacement therapy in male Ames dwarf mice are transient.

Published in:

Experimental Biology & Medicine, 2016, v. 241, n. 16, p. 1764, doi. 10.1177/1535370216650292

By:

Darcy, Justin;
Fang, Yimin;
Hill, Cristal M.;
McFadden, Sam;
Sun, Liou Y.;
Bartke, Andrzej

Publication type:

Article

Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity.

Published in:

GeroScience, 2020, v. 42, n. 6, p. 1527, doi. 10.1007/s11357-020-00221-0

By:

Darcy, Justin;
Fang, Yimin;
McFadden, Samuel;
Lynes, Matthew D.;
Leiria, Luiz O.;
Dreyfuss, Jonathan M.;
Bussburg, Valerie;
Tolstikov, Vladimir;
Greenwood, Bennett;
Narain, Niven R.;
Kiebish, Michael A.;
Bartke, Andrzej;
Tseng, Yu-Hua

Publication type:

Article

ComBATing aging—does increased brown adipose tissue activity confer longevity?

Published in:

GeroScience, 2019, v. 41, n. 3, p. 285, doi. 10.1007/s11357-019-00076-0

By:

Darcy, Justin;
Tseng, Yu-Hua

Publication type:

Article

Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice.

Published in:

GeroScience, 2017, v. 39, n. 3, p. 347, doi. 10.1007/s11357-017-9978-6

By:

Fang, Yimin;
McFadden, Samuel;
Darcy, Justin;
Hill, Cristal;
Huber, Joshua;
Verhulst, Steve;
Kopchick, John;
Miller, Richard;
Sun, Liou;
Bartke, Andrzej

Publication type:

Article

Lifespan of long‐lived growth hormone receptor knockout mice was not normalized by housing at 30°C since weaning.

Published in:

Aging Cell, 2020, v. 19, n. 5, p. 1, doi. 10.1111/acel.13123

By:

Fang, Yimin;
McFadden, Samuel;
Darcy, Justin;
Hascup, Erin R.;
Hascup, Kevin N.;
Bartke, Andrzej

Publication type:

Article

Energy Metabolism and Aging.

Published in:

World Journal of Men's Health, 2021, v. 39, n. 2, p. 222, doi. 10.5534/wjmh.200112

By:

Bartke, Andrzej;
Brannan, Savannah;
Hascup, Erin;
Hascup, Kevin;
Darcy, Justin

Publication type:

Article

Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 10, p. 5423, doi. 10.1093/nar/gkae350

By:

Yu, Mikyung;
Qin, June;
Liu, Xiumin;
Ramsden, Diane;
Williams, Brian;
Zlatev, Ivan;
Guenther, Dale;
Matsuda, Shigeo;
Tymon, Roxanne;
Darcy, Justin;
Wong, Catrina;
Tsung, Jamie;
Zawaneh, Peter;
Chong, Saeho;
Theile, Christopher S;
Taneja, Nathan;
Rogers, Arlin;
Liu, Ju;
Castellanos-Rizaldos, Elena;
Bond, Sarah

Publication type:

Article

CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice.

Published in:

Science Translational Medicine, 2020, v. 12, n. 558, p. 1, doi. 10.1126/scitranslmed.aaz8664

By:

Wang, Chih-Hao;
Lundh, Morten;
Fu, Accalia;
Kriszt, Rókus;
Huang, Tian Lian;
Lynes, Matthew D.;
Leiria, Luiz O.;
Shamsi, Farnaz;
Darcy, Justin;
Greenwood, Bennett P.;
Narain, Niven R.;
Tolstikov, Vladimir;
Smith, Kyle L.;
Emanuelli, Brice;
Chang, Young-Tae;
Hagen, Susan;
Danial, Nika N.;
Kiebish, Michael A.;
Tseng, Yu-Hua

Publication type:

Article

1999-P: Cysteine-Rich Protein 2 (CRIP2) Is a Novel Transcriptional Regulator of Uncoupling Protein 1.

Published in:

Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1999-P

By:

DARCY, JUSTIN;
WANG, CHIH-HAO;
LUNDH, MORTEN;
SHAMSI, FARNAZ;
LYNES, MATTHEW;
D'APRIGNY, THOMAS;
EMANUELLI, BRICE;
TSENG, YU-HUA

Publication type:

Article

Growth Hormone Signaling Shapes the Impact of Environmental Temperature on Transcriptomic Profile of Different Adipose Tissue Depots in Male Mice.

Published in:

2022

By:

Schneider, Augusto;
Victoria, Berta;
Cousen, Maria Isabel Schiavon;
Fang, Yimin;
McFadden, Samuel;
Darcy, Justin;
Gesing, Adam;
Hascup, Erin R;
Hascup, Kevin N;
Bartke, Andrzej;
Masternak, Michal M;
Schiavon Cousen, Maria Isabel

Publication type:

journal article

17α-Estradiol Modulates IGF1 and Hepatic Gene Expression in a Sex-Specific Manner.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2021, v. 76, n. 5, p. 778, doi. 10.1093/gerona/glaa215

By:

Sidhom, Silvana;
Schneider, Augusto;
Yimin Fang;
McFadden, Samuel;
Darcy, Justin;
Sathiaseelan, Roshini;
Palmer, Allyson K.;
Steyn, Frederik J.;
Grillari, Johannes;
Kopchick, John J.;
Bartke, Andrzej;
Siddiqi, Shadab;
Masternak, Michal M.;
Stout, Michael B.

Publication type:

Article