Works by Danishefsky, Samuel

Results: 131

Eine faszinierende Reise in die Geschichte: Isonitrile als Ausgangsverbindungen für komplexe Amide.

Published in:

Angewandte Chemie, 2012, v. 124, n. 12, p. 2888, doi. 10.1002/ange.201106628

By:

Wilson, Rebecca M.;
Stockdill, Jennifer L.;
Wu, Xiangyang;
Li, Xuechen;
Vadola, Paul A.;
Park, Peter K.;
Wang, Ping;
Danishefsky, Samuel J.

Publication type:

Article

Probing the Frontiers of Glycoprotein Synthesis: The Fully Elaborated β-Subunit of the Human Follicle-Stimulating Hormone.

Published in:

Angewandte Chemie, 2012, v. 124, n. 4, p. 999, doi. 10.1002/ange.201107482

By:

Nagorny, Pavel;
Sane, Neeraj;
Fasching, Bernhard;
Aussedat, Baptiste;
Danishefsky, Samuel J.

Publication type:

Article

Experimental Diels-Alder Reactivities of Cycloalkenones and Cyclic Dienes Explained through Transition-State Distortion Energies.

Published in:

Angewandte Chemie, 2011, v. 123, n. 44, p. 10550, doi. 10.1002/ange.201103998

By:

Paton, Robert S.;
Kim, Seonah;
Ross, Audrey G.;
Danishefsky, Samuel J.;
Houk, K. N.

Publication type:

Article

Insights into the Finer Issues of Native Chemical Ligation: An Approach to Cascade Ligations.

Published in:

Angewandte Chemie, 2010, v. 122, n. 49, p. 9690, doi. 10.1002/ange.201005513

By:

Tan, Zhongping;
Shang, Shiying;
Danishefsky, Samuel J.

Publication type:

Article

Zum Wirkungsbereich der chemischen Synthese: Aufbau einer Minipipeline in einem akademischen Labor.

Published in:

Angewandte Chemie, 2010, v. 122, n. 35, p. 6168, doi. 10.1002/ange.201000775

By:

Wilson, Rebecca M.;
Danishefsky, Samuel J.

Publication type:

Article

Titelbild: Zum Wirkungsbereich der chemischen Synthese: Aufbau einer Minipipeline in einem akademischen Labor (Angew. Chem. 35/2010).

Published in:

Angewandte Chemie, 2010, v. 122, n. 35, p. 6139, doi. 10.1002/ange.201004265

By:

Wilson, Rebecca M.;
Danishefsky, Samuel J.

Publication type:

Article

Building Complex Glycopeptides: Development of a Cysteine-Free Native Chemical Ligation ProtocolThis work was supported by the National Institutes of Health (Grant CA28824 to S.J.D., and CA62948 to J.D.W.) and by New York State Department of Health, New York State Breast Cancer Research and Education Fund (to B.W.).

Published in:

Angewandte Chemie, 2006, v. 118, n. 25, p. 4222, doi. 10.1002/ange.200600538

By:

Bin Wu;
Jiehao Chen;
J. David Warren;
Gong Chen;
Zihao Hua;
Samuel J. Danishefsky

Publication type:

Article

Titelbild: Der Weg zu Fludelon: ein Tumortherapeutikum mit außergewöhnlichen Eigenschaften (Angew. Chem. 19/2005).

Published in:

Angewandte Chemie, 2005, v. 117, n. 19, p. 2877, doi. 10.1002/ange.200590063

By:

Alexey Rivkin;
Ting-Chao Chou;
Samuel J. Danishefsky

Publication type:

Article

Der Weg zu Fludelon: ein Tumortherapeutikum mit außergewöhnlichen Eigenschaften.

Published in:

Angewandte Chemie, 2005, v. 117, n. 19, p. 2898, doi. 10.1002/ange.200461751

By:

Alexey Rivkin;
Ting-Chao Chou;
Samuel J. Danishefsky

Publication type:

Article

A Synthetic Pathway to Either Enantiomer of Merrilactone A.

Published in:

Angewandte Chemie, 2005, v. 117, n. 10, p. 1535, doi. 10.1002/ange.200462509

By:

Zhaoyang Meng;
Samuel J. Danishefsky

Publication type:

Article

In Pursuit of Carbohydrate-Based HIV Vaccines, Part 2: The Total Synthesis of High-Mannose-Type gp120 FragmentsEvaluation of Strategies Directed to Maximal Convergence ( This work was supported by the National Institutes of Health (CA-28824). US Army Breast Cancer Foundation postdoctoral fellowship support is gratefully acknowledged by X.G. (BC022120) and V.D. (BC020513). We thank Ms. Anna Dudkina and Ms. Sylvi Rusli (NMR Core Facility, CA-02848) for mass spectrometric analyses, Dr. George Sukenic for NMR spectroscopic analyses, and Dr. J. David Warren for help in the preparation of starting materials. We also thank Dr. Justin S. Miller, Dr. Tom Muir, Mr. Michael Hahn, and Mr. Matthew Sekedat for their generous help in the preparation of the peptides. )

Published in:

Angewandte Chemie, 2004, v. 116, n. 19, p. 2616, doi. 10.1002/ange.200353626

By:

Xudong Geng;
Vadim Y. Dudkin;
Mihirbaran Mandal;
Samuel J. Danishefsky

Publication type:

Article

Toward Homogeneous Erythropoietin: Application of Metal-Free Dethiylation in the Chemical Synthesis of the Ala79-Arg166 Glycopeptide Domain.

Published in:

Israel Journal of Chemistry, 2011, v. 51, n. 8/9, p. 968, doi. 10.1002/ijch.201100077

By:

Dong, Suwei;
Shang, Shiying;
Tan, Zhongping;
Danishefsky, Samuel J.

Publication type:

Article

Toward Fully Synthetic Homogeneous Glycoproteins: A High Mannose Core Containing Glycopeptide Carrying Full H-Type 2 Human Blood Group Specificity.

Published in:

Angewandte Chemie, 2001, v. 113, n. 9, p. 1778, doi. 10.1002/1521-3757(20010504)113:9<1778::AID-ANGE17780>3.0.CO;2-K

By:

Wang, Zhi-Guang;
Zhang, Xufang;
Visser, Michael;
Live, David;
Zatorski, Andrzej;
Iserloh, Ulrich;
Lloyd, Kenneth O.;
Danishefsky, Samuel J.

Publication type:

Article

Die Totalsynthese von (±)-Mitomycin K.

Published in:

Angewandte Chemie, 1992, v. 104, n. 7, p. 934, doi. 10.1002/ange.19921040743

By:

Benbow, John W.;
Schulte, Gayle K.;
Danishefsky, Samuel J.

Publication type:

Article

Potent reversal of multidrug resistance by ningalins and its use in drug combinations against human colon carcinoma xenograft in nude mice.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 4, p. 379, doi. 10.1007/s00280-005-1019-y

By:

Ting-Chao Chou;
Yongbiao Guan;
Soenen, Danielle R.;
Danishefsky, Samuel J.;
Boger, Dale L.

Publication type:

Article

Chemistry as an Expanding Resource in Protein Science: Fully Synthetic and Fully Active Human Parathyroid Hormone-Related Protein (1 -141).

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 49, p. 12263, doi. 10.1002/anie.201207603

By:

Li, Jianfeng;
Dong, Suwei;
Townsend, Steven D.;
Dean, Thomas;
Gardella, Thomas J.;
Danishefsky, Samuel J.

Publication type:

Article

Cover Picture: At Last: Erythropoietin as a Single Glycoform (Angew. Chem. Int. Ed. 46/2012).

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 46, p. 11391, doi. 10.1002/anie.201208087

By:

Wang, Ping;
Dong, Suwei;
Brailsford, John A.;
Iyer, Karthik;
Townsend, Steven D.;
Zhang, Qiang;
Hendrickson, Ronald C.;
Shieh, JaeHung;
Moore, Malcolm A. S.;
Danishefsky, Samuel J.

Publication type:

Article

An Advance in the Chemical Synthesis of Homogeneous N-Linked Glycopolypeptides by Convergent Aspartylation.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 46, p. 11571, doi. 10.1002/anie.201205038

By:

Wang, Ping;
Aussedat, Baptiste;
Vohra, Yusufbhai;
Danishefsky, Samuel J.

Publication type:

Article

At Last: Erythropoietin as a Single Glycoform.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 46, p. 11576, doi. 10.1002/anie.201206090

By:

Wang, Ping;
Dong, Suwei;
Brailsford, John A.;
Iyer, Karthik;
Townsend, Steven D.;
Zhang, Qiang;
Hendrickson, Ronald C.;
Shieh, JaeHung;
Moore, Malcolm A. S.;
Danishefsky, Samuel J.

Publication type:

Article

A Fascinating Journey into History: Exploration of the World of Isonitriles En Route to Complex Amides.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 12, p. 2834, doi. 10.1002/anie.201106628

By:

Wilson, Rebecca M.;
Stockdill, Jennifer L.;
Wu, Xiangyang;
Li, Xuechen;
Vadola, Paul A.;
Park, Peter K.;
Wang, Ping;
Danishefsky, Samuel J.

Publication type:

Article

Probing the Frontiers of Glycoprotein Synthesis: The Fully Elaborated β-Subunit of the Human Follicle-Stimulating Hormone.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 4, p. 975, doi. 10.1002/anie.201107482

By:

Nagorny, Pavel;
Sane, Neeraj;
Fasching, Bernhard;
Aussedat, Baptiste;
Danishefsky, Samuel J.

Publication type:

Article

Experimental Diels-Alder Reactivities of Cycloalkenones and Cyclic Dienes Explained through Transition-State Distortion Energies.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 44, p. 10366, doi. 10.1002/anie.201103998

By:

Paton, Robert S.;
Kim, Seonah;
Ross, Audrey G.;
Danishefsky, Samuel J.;
Houk, K. N.

Publication type:

Article

Insights into the Finer Issues of Native Chemical Ligation: An Approach to Cascade Ligations.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 49, p. 9500, doi. 10.1002/anie.201005513

By:

Tan, Zhongping;
Shang, Shiying;
Danishefsky, Samuel J.

Publication type:

Article

On the Reach of Chemical Synthesis: Creation of a Mini-Pipeline from an Academic Laboratory.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 35, p. 6032, doi. 10.1002/anie.201000775

By:

Wilson, Rebecca M.;
Danishefsky, Samuel J.

Publication type:

Article

Cover Picture: On the Reach of Chemical Synthesis: Creation of a Mini-Pipeline from an Academic Laboratory (Angew. Chem. Int. Ed. 35/2010).

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 35, p. 6003, doi. 10.1002/anie.201004265

By:

Wilson, Rebecca M.;
Danishefsky, Samuel J.

Publication type:

Article

Native Chemical Ligation at Valine: A Contribution to Peptide and Glycopeptide Synthesis.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 44, p. 8521, doi. 10.1002/anie.200803523

By:

Chen, Jin;
Wan, Qian;
Yuan, Yu;
Zhu, Jianglong;
Danishefsky, Samuel J.

Publication type:

Article

Free-Radical-Based, Specific Desulfurization of Cysteine: A Powerful Advance in the Synthesis of Polypeptides and Glycopolypeptides.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 48, p. 9248, doi. 10.1002/anie.200704195

By:

Wan, Qian;
Danishefsky, Samuel J.

Publication type:

Article

Differentiation of Nonconventional 'Carbanions'-The Total Synthesis of Nemorosone and Clusianone.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 46, p. 8840, doi. 10.1002/anie.200703886

By:

Tsukano, Chihiro;
Siegel, Dionicio R.;
Danishefsky, Samuel J.

Publication type:

Article

Conformational Locking through Allylic Strain as a Device for Stereocontrol-Total Synthesis of Grandisine A.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 41, p. 7789, doi. 10.1002/anie.200703245

By:

Maloney, David J.;
Danishefsky, Samuel J.

Publication type:

Article

Development of Efficient Methods for Accomplishing Cysteine-Free Peptide and Glycopeptide Coupling.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 39, p. 7383, doi. 10.1002/anie.200702865

By:

Chen, Gong;
Wan, Qian;
Tan, Zhongping;
Kan, Cindy;
Hua, Zihao;
Ranganathan, Krishnakumar;
Danishefsky, Samuel J.

Publication type:

Article

Total Synthesis of (+)-Isomigrastatin.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 29, p. 5576, doi. 10.1002/anie.200701837

By:

Krauss, Isaac J.;
Mandal, Mihirbaran;
Danishefsky, Samuel J.

Publication type:

Article

A letter from Professor Samuel J. Danishefsky.

Published in:

2019

By:

Danishefsky, Samuel J.

Publication type:

Editorial

Discovery through Total Synthesis: A Retrospective on the Himastatin Problem.

Published in:

Chemistry - A European Journal, 2001, v. 7, n. 1, p. 41, doi. 10.1002/1521-3765(20010105)7:1<41::AID-CHEM41>3.0.CO;2-D

By:

Kamenecka, Theodore M.;
Danishefsky, Samuel J.

Publication type:

Article

Cover Picture.

Published in:

Chemistry - A European Journal, 2001, v. 7, n. 1, p. 1, doi. 10.1002/1521-3765(20010105)7:1<1::AID-CHEM1>3.0.CO;2-0

By:

Kamenecka, Theodore M.;
Danishefsky, Samuel J.

Publication type:

Article

A Second Generation Synthesis of the MBr1 (Globo-H) Breast Tumor Antigen: New Application of the n-Pentenyl Glycoside Method for Achieving Complex Carbohydrate Protein Linkages.

Published in:

Chemistry - A European Journal, 2000, v. 6, n. 8, p. 1366, doi. 10.1002/(sici)1521-3765(20000417)6:8<1366::aid-chem1366>3.3.co;2-b

By:

Allen, Jennifer R.;
Allen, John G.;
Zhang, Xu-Feng;
Williams, Lawrence J.;
Zatorski, Andrzej;
Ragupathi, Govindaswami;
Livingston, Philip O.;
Danishefsky, Samuel J.

Publication type:

Article

A Highly Convergent Total Synthetic Route to Glycopeptides Carrying a High-Mannose Core Pentasaccharide Domain N-linked to a Natural Peptide Motif.

Published in:

Chemistry - A European Journal, 1997, v. 3, n. 10, p. 1617, doi. 10.1002/chem.19970031011

By:

Danishefsky, Samuel J.;
Hu, Shuanghua;
Cirillo, Pier F.;
Eckhardt, Matthias;
Seeberger, Peter H.

Publication type:

Article

A Paradigm Case for the Merging of Glycal and Enzymatic Assembly Methods in Glycoconjugate Synthesis: A Highly Efficient Chemo-Enzymatic Synthesis of GM<sub>3</sub>.

Published in:

Chemistry - A European Journal, 1996, v. 2, n. 11, p. 1359, doi. 10.1002/chem.19960021105

By:

Liu, Kevin K.-C.;
Danishefsky, Samuel J.

Publication type:

Article

Designing synthetic vaccines for HIV.

Published in:

Expert Review of Vaccines, 2015, v. 14, n. 6, p. 815, doi. 10.1586/14760584.2015.1027690

By:

Fernández-Tejada, Alberto;
Haynes, Barton F;
Danishefsky, Samuel J

Publication type:

Article

Constructing an adenocarcinoma vaccine: Immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Le.

Published in:

International Journal of Cancer, 2002, v. 99, n. 2, p. 207, doi. 10.1002/ijc.10305

By:

Ragupathi, Govindaswami;
Deshpande, Prashant P.;
Coltart, Don M.;
Kim, Hyunjin M.;
Williams, Lawrence J.;
Danishefsky, Samuel J.;
Livingston, Philip O.

Publication type:

Article

Immunization of ovarian cancer patients with a synthetic Lewis.

Published in:

International Journal of Cancer, 2000, v. 87, n. 1, p. 79, doi. 10.1002/1097-0215(20000701)87:1<79::AID-IJC12>3.0.CO;2-L

By:

Sabbatini, Paul J.;
Kudryashov, Valery;
Ragupathi, Govindaswami;
Danishefsky, Samuel J.;
Livingston, Philip O.;
Bornmann, William;
Spassova, Maria;
Zatorski, Andrzej;
Spriggs, David;
Aghajanian, Carol;
Soignet, Steven;
Peyton, Madeline;
O'Flaherty, Catherine;
Curtin, John;
Lloyd, Kenneth O.

Publication type:

Article

A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission.

Published in:

Cancers, 2016, v. 8, n. 4, p. 46, doi. 10.3390/cancers8040046

By:

O'Cearbhaill, Roisin E.;
Ragupathi, Govind;
Jianglong Zhu;
Qian Wan;
Mironov, Svetlana;
Guangbin Yang;
Spassova, Maria K.;
Iasonos, Alexia;
Kravetz, Sara;
Ouerfelli, Ouathek;
Spriggs, David R.;
Danishefsky, Samuel J.;
Sabbatini, Paul J.

Publication type:

Article

Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma.

Published in:

Investigational New Drugs, 2012, v. 30, n. 6, p. 2294, doi. 10.1007/s10637-011-9765-7

By:

Konner, Jason;
Grisham, Rachel;
Park, Jae;
O'Connor, Owen;
Cropp, Gillian;
Johnson, Robert;
Hannah, Alison;
Hensley, Martee;
Sabbatini, Paul;
Miranov, Svetlana;
Danishefsky, Samuel;
Hyman, David;
Spriggs, David;
Dupont, Jakob;
Aghajanian, Carol

Publication type:

Article

Erratum to: Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma.

Published in:

2012

By:

Konner, Jason;
Grisham, Rachel;
Park, Jae;
O'Connor, Owen;
Cropp, Gillian;
Johnson, Robert;
Hannah, Alison;
Hensley, Martee;
Sabbatini, Paul;
Mironov, Svetlana;
Danishefsky, Samuel;
Hyman, David;
Spriggs, David;
Dupont, Jakob;
Aghajanian, Carol

Publication type:

Correction Notice

Thomsen-Friedenreich (TF) antigen as a target for prostate cancer vaccine: clinical trial results with TF cluster (c)-KLH plus QS21 conjugate vaccine in patients with biochemically relapsed prostate cancer.

Published in:

Cancer Immunology, Immunotherapy, 2005, v. 54, n. 7, p. 694, doi. 10.1007/s00262-004-0598-5

By:

Slovin, Susan;
Ragupathi, Govind;
Musselli, Cristina;
Fernandez, Celina;
Diani, Meghan;
Verbel, David;
Danishefsky, Samuel;
Livingston, Philip;
Scher, Howard

Publication type:

Article

Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn.

Published in:

Cancer Immunology, Immunotherapy, 2005, v. 54, n. 5, p. 424, doi. 10.1007/s00262-004-0584-y

By:

Kagan, Ella;
Ragupathi, Govind;
Yi, San;
Reis, Celso;
Gildersleeve, Jeff;
Kahne, Daniel;
Clausen, Henrik;
Danishefsky, Samuel;
Livingston, Philip

Publication type:

Article

A preclinical study comparing approaches for augmenting the immunogenicity of a heptavalent KLH-conjugate vaccine against epithelial cancers.

Published in:

Cancer Immunology, Immunotherapy, 2003, v. 52, n. 10, p. 608, doi. 10.1007/s00262-003-0399-2

By:

Ragupathi, Govind;
Koide, Fusataka;
Sathyan, Natarajan;
Kagan, Ella;
Spassova, Maria;
Bornmann, William;
Gregor, Polly;
Reis, Celso A.;
Clausen, Henrik;
Danishefsky, Samuel J.;
Livingston, Philip O.

Publication type:

Article

Total synthesis of the potential anticancer vaccine KH-1 adenocarcinoma antigen.

Published in:

Nature, 1997, v. 387, n. 6629, p. 164, doi. 10.1038/387164a0

By:

Deshpande, Prashant P.;
Danishefsky, Samuel J.

Publication type:

Article

Total Synthesis of Paecilomycine A.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 13, p. 2199, doi. 10.1002/anie.200605058

By:

Min, Sun-Joon;
Danishefsky, Samuel J.

Publication type:

Article

Total Synthesis of Peribysin E Necessitates Revision of the Assignment of its Absolute Configuration.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 9, p. 1451, doi. 10.1002/anie.200604308

By:

Angeles, Angie R.;
Dorn, David C.;
Kou, Cynthia A.;
Moore, Malcolm A. S.;
Danishefsky, Samuel J.

Publication type:

Article

Total Synthesis of Phalarine.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 9, p. 1448, doi. 10.1002/anie.200604072

By:

Li, Chaomin;
Chan, Collin;
Heimann, Annekatrin C.;
Danishefsky, Samuel J.

Publication type:

Article