Works by Dal Ben, Diego

Results: 34

Pharmacological postconditioning of the rabbit heart with non-selective, A1, A2A and A3 adenosine receptor agonists.

Published in:

Journal of Pharmacy & Pharmacology, 2014, v. 66, n. 8, p. 1140, doi. 10.1111/jphp.12238

By:

Bibli, Sophia‐Iris;
Iliodromitis, Efstathios K.;
Lambertucci, Catia;
Zoga, Anastasia;
Lougiakis, Nikolaos;
Dagres, Nikolaos;
Volpini, Rosaria;
Dal Ben, Diego;
Kremastinos, Dimitrios Th.;
Tsantili Kakoulidou, Anna;
Cristalli, Gloria;
Andreadou, Ioanna

Publication type:

Article

Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and A 2A Adenosine Receptor Useful in Neurodegenerative Disorders.

Published in:

Molecules, 2023, v. 28, n. 12, p. 4762, doi. 10.3390/molecules28124762

By:

Francucci, Beatrice;
Angeloni, Simone;
Dal Ben, Diego;
Lambertucci, Catia;
Ricciutelli, Massimo;
Spinaci, Andrea;
Smirnov, Aleksei;
Volpini, Rosaria;
Buccioni, Michela;
Marucci, Gabriella

Publication type:

Article

Machine Learning Scoring Functions for Drug Discovery from Experimental and Computer-Generated Protein–Ligand Structures: Towards Per-Target Scoring Functions.

Published in:

Molecules, 2023, v. 28, n. 4, p. 1661, doi. 10.3390/molecules28041661

By:

Pellicani, Francesco;
Dal Ben, Diego;
Perali, Andrea;
Pilati, Sebastiano

Publication type:

Article

A 2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable?

Published in:

Molecules, 2022, v. 27, n. 8, p. N.PAG, doi. 10.3390/molecules27082386

By:

Spinaci, Andrea;
Lambertucci, Catia;
Buccioni, Michela;
Dal Ben, Diego;
Graiff, Claudia;
Barbalace, Maria Cristina;
Hrelia, Silvana;
Angeloni, Cristina;
Tayebati, Seyed Khosrow;
Ubaldi, Massimo;
Masi, Alessio;
Klotz, Karl-Norbert;
Volpini, Rosaria;
Marucci, Gabriella

Publication type:

Article

Combined Therapy of A 1 AR Agonists and A 2A AR Antagonists in Neuroinflammation.

Published in:

Molecules, 2021, v. 26, n. 4, p. 1188, doi. 10.3390/molecules26041188

By:

Marucci, Gabriella;
Ben, Diego Dal;
Lambertucci, Catia;
Navia, Aleix Martí;
Spinaci, Andrea;
Volpini, Rosaria;
Buccioni, Michela;
Geronikaki, Athina;
Lavandera, Jose Luis

Publication type:

Article

Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A2A Adenosine Receptor.

Published in:

Molecular Informatics, 2016, v. 35, n. 8/9, p. 403, doi. 10.1002/minf.201501042

By:

Dal Ben, Diego;
Buccioni, Michela;
Lambertucci, Catia;
Marucci, Gabriella;
Santinelli, Claudia;
Spinaci, Andrea;
Thomas, Ajiroghene;
Volpini, Rosaria

Publication type:

Article

Purinergic Ligands as Potential Therapeutic Tools for the Treatment of Inflammation-Related Intestinal Diseases.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00212

By:

Dal Ben, Diego;
Antonioli, Luca;
Lambertucci, Catia;
Fornai, Matteo;
Blandizzi, Corrado;
Volpini, Rosaria

Publication type:

Article

Approaches for designing and discovering purinergic drugs for gastrointestinal diseases.

Published in:

Expert Opinion on Drug Discovery, 2020, v. 15, n. 6, p. 687, doi. 10.1080/17460441.2020.1743673

By:

Dal Ben, Diego;
Antonioli, Luca;
Lambertucci, Catia;
Spinaci, Andrea;
Fornai, Matteo;
D'Antongiovanni, Vanessa;
Pellegrini, Carolina;
Blandizzi, Corrado;
Volpini, Rosaria

Publication type:

Article

The G Protein-Coupled Receptor GPR17: Overview and Update.

Published in:

ChemMedChem, 2016, v. 11, n. 23, p. 2567, doi. 10.1002/cmdc.201600453

By:

Marucci, Gabriella;
Dal Ben, Diego;
Lambertucci, Catia;
Santinelli, Claudia;
Spinaci, Andrea;
Thomas, Ajiroghene;
Volpini, Rosaria;
Buccioni, Michela

Publication type:

Article

The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor.

Published in:

ChemMedChem, 2016, v. 11, n. 16, p. 1829, doi. 10.1002/cmdc.201500595

By:

Thomas, Ajiroghene;
Buccioni, Michela;
Dal Ben, Diego;
Lambertucci, Catia;
Marucci, Gabriella;
Santinelli, Claudia;
Spinaci, Andrea;
Kachler, Sonja;
Klotz, Karl‐Norbert;
Volpini, Rosaria

Publication type:

Article

A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus.

Published in:

ChemMedChem, 2016, v. 11, n. 16, p. 1819, doi. 10.1002/cmdc.201600022

By:

Mammoli, Valerio;
Bonifazi, Alessandro;
Dal Ben, Diego;
Giannella, Mario;
Giorgioni, Gianfabio;
Piergentili, Alessandro;
Pigini, Maria;
Quaglia, Wilma;
Thomas, Ajiroghene;
Newman, Amy H.;
Ferré, Sergi;
Sanchez‐Soto, Marta;
Keck, Thomas M.;
Del Bello, Fabio

Publication type:

Article

Neuropeptide S Receptor: Recent Updates on Nonpeptide Antagonist Discovery.

Published in:

ChemMedChem, 2011, v. 6, n. 7, p. 1163, doi. 10.1002/cmdc.201100038

By:

Dal Ben, Diego;
Antonini, Ippolito;
Buccioni, Michela;
Lambertucci, Catia;
Marucci, Gabriella;
Thomas, Ajiroghene;
Volpini, Rosaria;
Cristalli, Gloria

Publication type:

Article

Inside Cover: Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine (ChemMedChem 6/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 6, p. 946, doi. 10.1002/cmdc.201190024

By:

Volpini, Rosaria;
Marucci, Gabriella;
Buccioni, Michela;
Dal Ben, Diego;
Lambertucci, Catia;
Lammi, Carmen;
Mishra, Ram C.;
Thomas, Ajiroghene;
Cristalli, Gloria

Publication type:

Article

Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine.

Published in:

ChemMedChem, 2011, v. 6, n. 6, p. 1074, doi. 10.1002/cmdc.201100100

By:

Volpini, Rosaria;
Marucci, Gabriella;
Buccioni, Michela;
Dal Ben, Diego;
Lambertucci, Catia;
Lammi, Carmen;
Mishra, Ram C.;
Thomas, Ajiroghene;
Cristalli, Gloria

Publication type:

Article

Adenosine A2A Receptor Antagonists: New 8-Substituted 9-Ethyladenines as Tools for in vivo Rat Models of Parkinson's Disease.

Published in:

ChemMedChem, 2009, v. 4, n. 6, p. 1010, doi. 10.1002/cmdc.200800434

By:

Volpini, Rosaria;
Dal Ben, Diego;
Lambertucci, Catia;
Marucci, Gabriella;
Mishra, Ram Chandra;
Ramadori, Anna Teresa;
Klotz, Karl-Norbert;
Trincavelli, Maria Letizia;
Martini, Claudia;
Cristalli, Gloria

Publication type:

Article

Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists.

Published in:

ChemMedChem, 2007, v. 2, n. 3, p. 260, doi. 10.1002/cmdc.200600193

By:

Cristalli, Gloria;
Cacciari, Barbara;
Dal Ben, Diego;
Lambertucci, Catia;
Moro, Stefano;
Spalluto, Giampiero;
Volpini, Rosaria

Publication type:

Article

P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.653561

By:

Spinaci, Andrea;
Buccioni, Michela;
Dal Ben, Diego;
Marucci, Gabriella;
Volpini, Rosaria;
Lambertucci, Catia

Publication type:

Article

Antiproliferative evaluation of isofuranodiene on breast and prostate cancer cell lines.

Published in:

2014

By:

Buccioni, Michela;
Dal Ben, Diego;
Lambertucci, Catia;
Maggi, Filippo;
Papa, Fabrizio;
Thomas, Ajiroghene;
Santinelli, Claudia;
Marucci, Gabriella

Publication type:

journal article

Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines.

Published in:

Scientific World Journal, 2014, p. 1, doi. 10.1155/2014/264829

By:

Buccioni, Michela;
Dal Ben, Diego;
Lambertucci, Catia;
Maggi, Filippo;
Papa, Fabrizio;
Thomas, Ajiroghene;
Santinelli, Claudia;
Marucci, Gabriella

Publication type:

Article

Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel F-labelled PET tracer targeting P2X7.

Published in:

EJNMMI Research, 2017, v. 7, n. 1, p. 1, doi. 10.1186/s13550-017-0275-2

By:

Fantoni, Enrico Raffaele;
Dal Ben, Diego;
Falzoni, Simonetta;
Di Virgilio, Francesco;
Lovestone, Simon;
Gee, Antony

Publication type:

Article

Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia.

Published in:

Journal of Neurochemistry, 2019, v. 149, n. 2, p. 211, doi. 10.1111/jnc.14660

By:

Martire, Alberto;
Lambertucci, Catia;
Pepponi, Rita;
Ferrante, Antonella;
Benati, Nicholas;
Buccioni, Michela;
Dal Ben, Diego;
Marucci, Gabriella;
Klotz, Karl‐Norbert;
Volpini, Rosaria;
Popoli, Patrizia

Publication type:

Article

"Dual Anta-Inhibitors" of the A 2A Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 2, p. 167, doi. 10.3390/ph16020167

By:

Spinaci, Andrea;
Buccioni, Michela;
Catarzi, Daniela;
Cui, Chang;
Colotta, Vittoria;
Dal Ben, Diego;
Cescon, Eleonora;
Francucci, Beatrice;
Grieco, Ilenia;
Lambertucci, Catia;
Marucci, Gabriella;
Bassani, Davide;
Pavan, Matteo;
Varano, Flavia;
Federico, Stephanie;
Spalluto, Giampiero;
Moro, Stefano;
Volpini, Rosaria

Publication type:

Article

4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 4, p. N.PAG, doi. 10.3390/ph15040478

By:

Catarzi, Daniela;
Varano, Flavia;
Vigiani, Erica;
Calenda, Sara;
Melani, Fabrizio;
Varani, Katia;
Vincenzi, Fabrizio;
Pasquini, Silvia;
Mennini, Natascia;
Nerli, Giulia;
Dal Ben, Diego;
Volpini, Rosaria;
Colotta, Vittoria

Publication type:

Article

A 3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 2, p. 164, doi. 10.3390/ph15020164

By:

Spinaci, Andrea;
Buccioni, Michela;
Dal Ben, Diego;
Maggi, Federica;
Marucci, Gabriella;
Francucci, Beatrice;
Santoni, Giorgio;
Lambertucci, Catia;
Volpini, Rosaria

Publication type:

Article

Design and Synthesis of Novel Thiazolo[5,4-d]pyrimidine Derivatives with High Affinity for Both the Adenosine A 1 and A 2A Receptors, and Efficacy in Animal Models of Depression.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 7, p. 657, doi. 10.3390/ph14070657

By:

Varano, Flavia;
Catarzi, Daniela;
Vigiani, Erica;
Dal Ben, Diego;
Buccioni, Michela;
Marucci, Gabriella;
Di Cesare Mannelli, Lorenzo;
Lucarini, Elena;
Ghelardini, Carla;
Volpini, Rosaria;
Colotta, Vittoria

Publication type:

Article

Amino-3,5-Dicyanopyridines Targeting the Adenosine Receptors. Ranging from Pan Ligands to Combined A1/A2B Partial Agonists.

Published in:

Pharmaceuticals (14248247), 2019, v. 12, n. 4, p. 159, doi. 10.3390/ph12040159

By:

Catarzi, Daniela;
Varano, Flavia;
Varani, Katia;
Vincenzi, Fabrizio;
Pasquini, Silvia;
Dal Ben, Diego;
Volpini, Rosaria;
Colotta, Vittoria

Publication type:

Article

Non-Nucleoside Agonists of the Adenosine Receptors: An Overview.

Published in:

Pharmaceuticals (14248247), 2019, v. 12, n. 4, p. 150, doi. 10.3390/ph12040150

By:

Dal Ben, Diego;
Lambertucci, Catia;
Buccioni, Michela;
Martí Navia, Aleix;
Marucci, Gabriella;
Spinaci, Andrea;
Volpini, Rosaria

Publication type:

Article

A 2A Adenosine Receptor Antagonists and Their Efficacy in Rat Models of Parkinson's Disease.

Published in:

Cells (2073-4409), 2025, v. 14, n. 5, p. 338, doi. 10.3390/cells14050338

By:

Spinaci, Andrea;
Buccioni, Michela;
Dal Ben, Diego;
Francucci, Beatrice;
Klotz, Karl-Norbert;
Marucci, Gabriella;
Simola, Nicola;
Morelli, Micaela;
Pinna, Annalisa;
Volpini, Rosaria;
Lambertucci, Catia

Publication type:

Article

Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1739, doi. 10.3390/cells9071739

By:

Martí Navia, Aleix;
Dal Ben, Diego;
Lambertucci, Catia;
Spinaci, Andrea;
Volpini, Rosaria;
Marques-Morgado, Inês;
Coelho, Joana E.;
Lopes, Luísa V.;
Marucci, Gabriella;
Buccioni, Michela

Publication type:

Article

The Anti-Inflammatory and Pain-Relieving Effects of AR170, an Adenosine A3 Receptor Agonist, in a Rat Model of Colitis.

Published in:

Cells (2073-4409), 2020, v. 9, n. 6, p. 1509, doi. 10.3390/cells9061509

By:

Antonioli, Luca;
Lucarini, Elena;
Lambertucci, Catia;
Fornai, Matteo;
Pellegrini, Carolina;
Benvenuti, Laura;
Di Cesare Mannelli, Lorenzo;
Spinaci, Andrea;
Marucci, Gabriella;
Blandizzi, Corrado;
Ghelardini, Carla;
Volpini, Rosaria;
Dal Ben, Diego

Publication type:

Article

A patent review of adenosine A2B receptor antagonists (2016-present).

Published in:

Expert Opinion on Therapeutic Patents, 2022, v. 32, n. 6, p. 689, doi. 10.1080/13543776.2022.2057222

By:

Francucci, Beatrice;
Dal Ben, Diego;
Lambertucci, Catia;
Spinaci, Andrea;
Volpini, Rosaria;
Marucci, Gabriella;
Buccioni, Michela

Publication type:

Article

Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications.

Published in:

Expert Opinion on Therapeutic Patents, 2019, v. 29, n. 12, p. 943, doi. 10.1080/13543776.2019.1693542

By:

Marucci, Gabriella;
Dal Ben, Diego;
Buccioni, Michela;
Martí Navia, Aleix;
Spinaci, Andrea;
Volpini, Rosaria;
Lambertucci, Catia

Publication type:

Article

GPR17 receptor modulators and their therapeutic implications: review of recent patents.

Published in:

Expert Opinion on Therapeutic Patents, 2019, v. 29, n. 2, p. 85, doi. 10.1080/13543776.2019.1568990

By:

Marucci, Gabriella;
Dal Ben, Diego;
Lambertucci, Catia;
Martí Navia, Aleix;
Spinaci, Andrea;
Volpini, Rosaria;
Buccioni, Michela

Publication type:

Article

Chaga Mushroom Triterpenoids Inhibit Dihydrofolate Reductase and Act Synergistically with Conventional Therapies in Breast Cancer.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 11, p. 1454, doi. 10.3390/biom14111454

By:

Wang, Junbiao;
Beghelli, Daniela;
Amici, Augusto;
Sut, Stefania;
Dall'Acqua, Stefano;
Lupidi, Giulio;
Dal Ben, Diego;
Bistoni, Onelia;
Tomassoni, Daniele;
Belletti, Barbara;
Musa, Sanaa;
Mahajna, Jamal;
Pucciarelli, Stefania;
Marchini, Cristina

Publication type:

Article

Works by Dal Ben, Diego

Pharmacological postconditioning of the rabbit heart with non-selective, A<sub>1</sub>, A<sub>2A</sub> and A<sub>3</sub> adenosine receptor agonists.

Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and A 2A Adenosine Receptor Useful in Neurodegenerative Disorders.

Machine Learning Scoring Functions for Drug Discovery from Experimental and Computer-Generated Protein–Ligand Structures: Towards Per-Target Scoring Functions.

A 2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable?

Combined Therapy of A 1 AR Agonists and A 2A AR Antagonists in Neuroinflammation.

Simulation and Comparative Analysis of Different Binding Modes of Non-nucleoside Agonists at the A<sub>2A</sub> Adenosine Receptor.

Purinergic Ligands as Potential Therapeutic Tools for the Treatment of Inflammation-Related Intestinal Diseases.

Approaches for designing and discovering purinergic drugs for gastrointestinal diseases.

The G Protein-Coupled Receptor GPR17: Overview and Update.

The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A<sub>2A</sub> Adenosine Receptor.

A Novel Class of Dopamine D<sub>4</sub> Receptor Ligands Bearing an Imidazoline Nucleus.

Neuropeptide S Receptor: Recent Updates on Nonpeptide Antagonist Discovery.

Inside Cover: Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine (ChemMedChem 6/2011).

Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine.

Adenosine A<sub>2A</sub> Receptor Antagonists: New 8-Substituted 9-Ethyladenines as Tools for in vivo Rat Models of Parkinson's Disease.

Highlights on the Development of A<sub>2A</sub> Adenosine Receptor Agonists and Antagonists.

P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications.

Antiproliferative evaluation of isofuranodiene on breast and prostate cancer cell lines.

Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines.

Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel F-labelled PET tracer targeting P2X7.

Neuroprotective potential of adenosine A<sub>1</sub> receptor partial agonists in experimental models of cerebral ischemia.

"Dual Anta-Inhibitors" of the A 2A Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies.

4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives.

A 3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity.

Design and Synthesis of Novel Thiazolo[5,4-d]pyrimidine Derivatives with High Affinity for Both the Adenosine A 1 and A 2A Receptors, and Efficacy in Animal Models of Depression.

Amino-3,5-Dicyanopyridines Targeting the Adenosine Receptors. Ranging from Pan Ligands to Combined A1/A2B Partial Agonists.

Non-Nucleoside Agonists of the Adenosine Receptors: An Overview.

A 2A Adenosine Receptor Antagonists and Their Efficacy in Rat Models of Parkinson's Disease.

Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists.

The Anti-Inflammatory and Pain-Relieving Effects of AR170, an Adenosine A3 Receptor Agonist, in a Rat Model of Colitis.

A patent review of adenosine A<sub>2B</sub> receptor antagonists (2016-present).

Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications.

GPR17 receptor modulators and their therapeutic implications: review of recent patents.

Chaga Mushroom Triterpenoids Inhibit Dihydrofolate Reductase and Act Synergistically with Conventional Therapies in Breast Cancer.