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PPARα‐independent action against metabolic syndrome development by fibrates is mediated by inhibition of STAT3 signalling.
Published in:
Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 12, p. 1630, doi. 10.1111/jphp.13014
By:
- Hua, Huiying;
- Yang, Julin;
- Lin, Hante;
- Xi, Yang;
- Dai, Manyun;
- Xu, Gangming;
- Wang, Fuyan;
- Liu, Lihong;
- Zhao, Tingqi;
- Huang, Jing;
- Gonzalez, Frank J.;
- Liu, Aiming
Publication type:
Article
Chlorogenic acid inhibits cholestatic liver injury induced by α-naphthylisothiocyanate: involvement of STAT3 and NFκB signalling regulation.
Published in:
Journal of Pharmacy & Pharmacology, 2016, v. 68, n. 9, p. 1203, doi. 10.1111/jphp.12592
By:
- Tan, Zhen;
- Luo, Min;
- Yang, Julin;
- Cheng, Yuqing;
- Huang, Jing;
- Lu, Caide;
- Song, Danjun;
- Ye, Meiling;
- Dai, Manyun;
- Gonzalez, Frank J.;
- Liu, Aiming;
- Guo, Bin
Publication type:
Article
Species-related exposure of phase II metabolite gemfibrozil 1-O-β-glucuronide between human and mice: A net induction of mouse P450 activity was revealed.
Published in:
Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 9, p. 535, doi. 10.1002/bdd.2105
By:
- Luo, Min;
- Dai, Manyun;
- Lin, Hante;
- Xie, Minzhu;
- Lin, Jiao;
- Liu, Aiming;
- Yang, Julin
Publication type:
Article
Inhibition of inflammation by SP600125 in cholestatic liver injury is dependent on the administration-based exposure profile.
Published in:
International Journal of Molecular Medicine, 2020, v. 46, n. 6, p. 2271, doi. 10.3892/ijmm.2020.4742
By:
- Zheng, Xiuting;
- Dai, Manyun;
- Xu, Gangming;
- Chang, Liming;
- Yang, Julin;
- Liu, Aiming
Publication type:
Article
Comparative Metabolomic Profiling of the Metabolic Differences of Δ9-Tetrahydrocannabinol and Cannabidiol.
Published in:
Molecules, 2022, v. 27, n. 21, p. 7573, doi. 10.3390/molecules27217573
By:
- Rao, Qianru;
- Zhang, Ting;
- Dai, Manyun;
- Li, Bin;
- Pu, Qianlun;
- Zhao, Min;
- Cheng, Yan;
- Yan, Dongmei;
- Zhao, Qi;
- Wu, Zhanxuan E.;
- Li, Fei
Publication type:
Article
Farnesoid X receptor regulators from natural products and their biological function.
Published in:
Journal of Traditional Chinese Medicine, 2023, v. 43, n. 3, p. 618, doi. 10.19852/j.cnki.jtcm.20230404.002
By:
- PENG Wan;
- NI Hengfan;
- GUO Dale;
- DENG Yun;
- DAI Manyun
Publication type:
Article
Cholestatic models induced by lithocholic acid and α-naphthylisothiocyanate: Different etiological mechanisms for liver injury but shared JNK/STAT3 signaling.
Published in:
Molecular Medicine Reports, 2020, v. 22, n. 2, p. 1583, doi. 10.3892/mmr.2020.11210
By:
- Xu, Gangming;
- Dai, Manyun;
- Zheng, Xiuting;
- Lin, Hante;
- Liu, Aiming;
- Yang, Julin
Publication type:
Article
Geniposide Inhibits Alpha-Naphthylisothiocyanate-Induced Intrahepatic Cholestasis: The Downregulation of STAT3 and NFB Signaling Plays an Important Role.
Published in:
American Journal of Chinese Medicine, 2016, v. 44, n. 4, p. 721, doi. 10.1142/S0192415X16500397
By:
- Tan, Zhen;
- Liu, Aiming;
- Luo, Min;
- Yin, Xuan;
- Song, Danjun;
- Dai, Manyun;
- Li, Pengxu;
- Chu, Zanbo;
- Zou, Zuquan;
- Ma, Ming;
- Guo, Bin;
- Chen, Bo
Publication type:
Article
Inhibition of JNK signalling mediates PPARα-dependent protection against intrahepatic cholestasis by fenofibrate.
Published in:
2017
By:
- Dai, Manyun;
- Yang, Julin;
- Xie, Minzhu;
- Lin, Jiao;
- Luo, Min;
- Hua, Huiying;
- Xu, Gangming;
- Lin, Hante;
- Song, Danjun;
- Cheng, Yuqing;
- Guo, Bin;
- Zhao, Jinshun;
- Gonzalez, Frank J;
- Liu, Aiming
Publication type:
journal article
PPARα-dependent increase of mouse urine output by gemfibrozil and fenofibrate.
Published in:
Canadian Journal of Physiology & Pharmacology, 2017, v. 95, n. 2, p. 199, doi. 10.1139/cjpp-2016-0140
By:
- Song, Danjun;
- Luo, Min;
- Dai, Manyun;
- Bu, Shizhong;
- Wang, Weihua;
- Zhang, Burong;
- Gonzalez, Frank J.;
- Liu, Aiming
Publication type:
Article
Dual action of peroxisome proliferator-activated receptor alpha in perfluorodecanoic acid-induced hepatotoxicity.
Published in:
Archives of Toxicology, 2017, v. 91, n. 2, p. 897, doi. 10.1007/s00204-016-1779-7
By:
- Luo, Min;
- Tan, Zhen;
- Dai, Manyun;
- Song, Danjun;
- Lin, Jiao;
- Xie, Minzhu;
- Wei, Dengming;
- Zhao, Jinshun;
- Liu, Aiming;
- Yang, Julin;
- Sun, Lu;
- Gonzalez, Frank
Publication type:
Article
Down-regulation of hepatic CLOCK by PPARα is involved in inhibition of NAFLD.
Published in:
Journal of Molecular Medicine, 2023, v. 101, n. 1/2, p. 139, doi. 10.1007/s00109-022-02279-z
By:
- Luo, Jia;
- Yan, Zheng;
- Dai, Manyun;
- Xu, Liping;
- Zhang, Haoyue;
- Xi, Yang;
- Yang, Julin;
- Liu, Aiming
Publication type:
Article
Aspirin Caused Intestinal Damage through FXR and ET-1 Signaling Pathways.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3424, doi. 10.3390/ijms25063424
By:
- Lin, Qiuxia;
- Zhang, Binbin;
- Dai, Manyun;
- Cheng, Yan;
- Li, Fei
Publication type:
Article
Peroxisome Proliferator-Activated Receptor α Activation Suppresses Cytochrome P450 Induction Potential in Mice Treated with Gemfibrozil.
Published in:
Basic & Clinical Pharmacology & Toxicology, 2017, v. 121, n. 3, p. 169, doi. 10.1111/bcpt.12794
By:
- Shi, Cunzhong;
- Min, Luo;
- Yang, Julin;
- Dai, Manyun;
- Song, Danjun;
- Hua, Huiying;
- Xu, Gangming;
- Gonzalez, Frank J.;
- Liu, Aiming
Publication type:
Article

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