Works by Dai, De‐Zai

Results: 41

ER Stress, P66shc, and P-Akt/Akt Mediate Adjuvant-Induced Inflammation, Which Is Blunted by Argirein, a Supermolecule and Rhein in Rats.

Published in:

Inflammation, 2012, v. 35, n. 3, p. 1031, doi. 10.1007/s10753-011-9407-4

By:

Cong, Xiao-Dong;
Ding, Ming-Jian;
Dai, De-Zai;
Wu, You;
Zhang, Yun;
Dai, Yin

Publication type:

Article

Role of endothelin receptor A and NADPH oxidase in vascular abnormalities.

Published in:

2010

By:

Dai DZ;
Dai Y;
Dai, De-Zai;
Dai, Yin

Publication type:

journal article

Hypoxia/oxidative stress alters the pharmacokinetics of CPU86017-RS through mitochondrial dysfunction and NADPH oxidase activation.

Published in:

Acta Pharmacologica Sinica, 2013, v. 34, n. 12, p. 1575, doi. 10.1038/aps.2013.94

By:

Gao, Jie;
Ding, Xuan-sheng;
Zhang, Yu-mao;
Dai, De-zai;
Liu, Mei;
Zhang, Can;
Dai, Yin

Publication type:

Article

Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx.

Published in:

Acta Pharmacologica Sinica, 2012, v. 33, n. 5, p. 625, doi. 10.1038/aps.2012.7

By:

Gao, Jie;
Tang, Yi-qun;
Dai, De-zai;
Cheng, Yu-si;
Zhang, Guo-lin;
Zhang, Can;
Dai, Yin

Publication type:

Article

CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines.

Published in:

Acta Pharmacologica Sinica, 2012, v. 33, n. 4, p. 470, doi. 10.1038/aps.2011.175

By:

Zhang, Guo-lin;
Yu, Feng;
Dai, De-zai;
Cheng, Yu-si;
Zhang, Can;
Dai, Yin

Publication type:

Article

Sildenafil and FDP-Sr attenuate diabetic cardiomyopathy by suppressing abnormal expression of myocardial CASQ2, FKBP12.6, and SERCA2a in rats.

Published in:

Acta Pharmacologica Sinica, 2011, v. 32, n. 4, p. 441, doi. 10.1038/aps.2010.226

By:

Cheng, Yu-si;
Dai, De-zai;
Ji, Hui;
Zhang, Qi;
Dai, Yin

Publication type:

Article

Isoproterenol-induced FKBP12.6/12 downregulation is modulated by ETA and ETB receptors and reversed by argirhein, a derivative of rhein.

Published in:

Acta Pharmacologica Sinica, 2011, v. 32, n. 2, p. 223, doi. 10.1038/aps.2010.177

By:

Zhang, Guo-lin;
Dai, De-zai;
Xi, Tao;
Cong, Xiao-dong;
Zhang, Yun;
Dai, Yin

Publication type:

Article

CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathway.

Published in:

Acta Pharmacologica Sinica, 2005, v. 26, n. 11, p. 1309, doi. 10.1111/j.1745-7254.2005.00214.x

By:

Zhang, Tian-tai;
Cui, Bing;
Dai, De-zai;
Su, Wei

Publication type:

Article

Argirein alleviates diabetic nephropathy through attenuating NADPH oxidase, Cx43, and PERK in renal tissue.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2011, v. 383, n. 3, p. 309, doi. 10.1007/s00210-010-0593-7

By:

Hu, C.;
Cong, X.;
Dai, De-Zai;
Zhang, Y.;
Zhang, G.;
Dai, Y.

Publication type:

Article

CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 378, n. 5, p. 541, doi. 10.1007/s00210-008-0309-4

By:

Li, Na;
Dai, De-Zai;
Dai, Yin

Publication type:

Article

Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2010, v. 37, n. 5/6, p. 557, doi. 10.1111/j.1440-1681.2010.05349.x

By:

Li, Na;
Jia, Nan;
Dai, De-Zai;
Hu, Chen;
Dai, Yin

Publication type:

Article

CPU0213, A NON-SELECTIVE ETA/ETB RECEPTOR ANTAGONIST, IMPROVES PULMONARY ARTERIOLAR REMODELING OF MONOCROTALINE-INDUCED PULMONARY HYPERTENSION IN RATS.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2009, v. 36, n. 2, p. 169, doi. 10.1111/j.1440-1681.2008.05044.x

By:

Cui, Bing;
Cheng, Yu-Si;
Dai, De-Zai;
Li, Na;
Zhang, Tian-Tai;
Dai, Yin

Publication type:

Article

EFFECT OF THE ENDOTHELIN RECEPTOR ANTAGONIST CPU0213, AND ITS MODULATION BY RIFAMPIN, ON CARDIAC AND VASCULAR TISSUE FOLLOWING CHRONIC ISOPROTERENOL TREATMENT.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2008, v. 35, n. 7, p. 757, doi. 10.1111/j.1440-1681.2007.04856.x

By:

Luo, Lu;
Dai, De-Zai;
Dai, Yin

Publication type:

Article

STRONTIUM FRUCTOSE 1,6-DIPHOSPHATE RESCUES ADENINE-INDUCED MALE HYPOGONADISM AND UPREGULATES THE TESTICULAR ENDOTHELIN-1 SYSTEM.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2007, v. 34, n. 11, p. 1131, doi. 10.1111/j.1440-1681.2007.04693.x

By:

Feng, Yu;
Zhang, Qi;
Dai, De-Zai;
Ying, Han-Jie;
Dai, Yin

Publication type:

Article

Cpu0507, An Endothelin Receptor Antagonist, Improves Rat Hypoxic Pulmonary Artery Hypertension And Constriction In Vivo And In Vitro.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2006, v. 33, n. 11, p. 1066, doi. 10.1111/j.1440-1681.2006.04488.x

By:

Yuan, Sheng-hua;
Dai, De-zai;
Guan, Li;
Dai, Yin;
Ji, Min

Publication type:

Article

CHRONIC LEVOTHYROXIN TREATMENT IS ASSOCIATED WITH ION CHANNEL ABNORMALITIES IN CARDIAC AND NEURONAL CELLS.

Published in:

Clinical & Experimental Pharmacology & Physiology, 1999, v. 26, n. 10, p. 819, doi. 10.1046/j.1440-1681.1999.03135.x

By:

Dai, DE-ZAI;
Hu, HUI-JUAN;
Yang, DONG-MEI;
Hao, XUE-MEI;
Zhang, GUANG-QIN;
Zhou, PEI-AI;
Wu, CAI-HONG

Publication type:

Article

Isoproterenol Induced Stressful Reactions in the Brain Are Characterized by Inflammation due to Activation of NADPH Oxidase and ER Stress: Attenuated by Apocynin, Rehmannia Complex and Triterpene Acids.

Published in:

Neurochemical Research, 2014, v. 39, n. 4, p. 719, doi. 10.1007/s11064-014-1260-z

By:

Mo, Guo-Long;
Li, Ying;
Du, Rong-hui;
Dai, De-Zai;
Cong, Xiao-Dong;
Dai, Yin

Publication type:

Article

Normalizing NADPH Oxidase Contributes to Attenuating Diabetic Nephropathy by the Dual Endothelin Receptor Antagonist CPU0213 in Rats.

Published in:

American Journal of Nephrology, 2009, v. 29, n. 3, p. 252, doi. 10.1159/000157628

By:

Xu, Ming;
Dai, De-Zai;
Dai, Yin

Publication type:

Article

Therapeutic effects of CPU 86017 on acute and chronic congestive cardiac failure mediated by reducing ET-1?NOS and oxidative stress in rats.

Published in:

Drug Development Research, 2004, v. 63, n. 1, p. 22, doi. 10.1002/ddr.10383

By:

Wang, Yong-Qing;
Shi, Yan-Ping;
Dai, De-Zai

Publication type:

Article

CPU 86017 suppresses tachyarrhythmias induced by ouabain and myocardial infarction: Concentrations in plasma and different areas of the heart in dogs.

Published in:

Drug Development Research, 2003, v. 58, n. 1, p. 131, doi. 10.1002/ddr.10142

By:

Cui, Yu-Jin;
Yang, Ping;
Dai, De-Zai;
Gao, Ling;
Xiao, Da-Wei;
Wang, You-Qun

Publication type:

Article

International Symposium on Cardiovascular Remodeling, Ion Channelopathies, Arrhythmias, and Drug Treatment.

Published in:

Drug Development Research, 2003, v. 58, n. 1, p. 1, doi. 10.1002/ddr.10146

By:

Dai, De Zai;
Triggle, David J.

Publication type:

Article

Two patterns of ion channelopathies relating to arrhythmias and direct and indirect blockade of ion channels by antiarrhythmic agents.

Published in:

Drug Development Research, 2003, v. 58, n. 1, p. 42, doi. 10.1002/ddr.10128

By:

Dai, De-Zai;
Zhang, Guang-Qin;
Yang, Ping;
Ma, Yu-Ping

Publication type:

Article

L-thyroxine-induced vasodilation impairment and increased vascular response to norepinephrine are mediated by dysfunctional NO release.

Published in:

Drug Development Research, 2003, v. 58, n. 1, p. 116, doi. 10.1002/ddr.10139

By:

Yang, Ping;
Dai, De-Zai

Publication type:

Article

L-thyroxine affects involvement of H1, 5-HT2, prostaglandin receptors and the endothelial NO system in allergic vascular response in guinea pigs.

Published in:

Drug Development Research, 2003, v. 58, n. 1, p. 125, doi. 10.1002/ddr.10141

By:

Hu, Hui-Juan;
Dai, De-Zai

Publication type:

Article

Reduced sodium currents in isolated mammalian myocytes treated with chronic L-thyroxine.

Published in:

Drug Development Research, 2003, v. 58, n. 1, p. 111, doi. 10.1002/ddr.10138

By:

Ma, Yu-Ping;
Hu, Hui-Juan;
Hao, Xue-Mei;
Zhou, Pei-Ai;
Wu, Cai-Hong;
Dai, De-Zai

Publication type:

Article

CPU 86017 suppression of arrhythmias induced by ischemia/reperfusion, ouabain, aconitine, and elevation of ventricular fibrillatory threshold.

Published in:

Drug Development Research, 1996, v. 39, n. 2, p. 184, doi. 10.1002/(SICI)1098-2299(199610)39:2<184::AID-DDR12>3.0.CO;2-C

By:

Dai, De-Zai;
An, Lu-Fan;
Wang, You-Qun;
Huang, Jun;
Zhang, Hua;
Dai, Dong;
Yu, Feng;
Zhang, Meng-Hui;
Huang, Zhen-Ya;
Peng, Si-Xun

Publication type:

Article

Comparison of protection by propranolol, bepridil, verapamil, and captopril on depleting ATP, ADP, and AMP in heart, brain, and liver by anoxia plus isoprenaline.

Published in:

Drug Development Research, 1996, v. 39, n. 2, p. 125, doi. 10.1002/(SICI)1098-2299(199610)39:2<125::AID-DDR2>3.0.CO;2-R

By:

Dai, De-Zai;
Zhu, Yuan;
Tian, Ying;
Chen, Shi-Hong;
Wang, Hong

Publication type:

Article

Advances in Chinese medicines.

Published in:

Drug Development Research, 1996, v. 39, n. 2, p. 123, doi. 10.1002/(SICI)1098-2299(199610)39:2<123::AID-DDR1>3.0.CO;2-R

By:

Dai, De-Zai

Publication type:

Article

Blockade on sodium, potassium, and calcium channels by a new antiarrhythmic agent CPU 86017.

Published in:

Drug Development Research, 1996, v. 39, n. 2, p. 138, doi. 10.1002/(SICI)1098-2299(199610)39:2<138::AID-DDR5>3.0.CO;2-Q

By:

Dai, De-Zai;
Yu, Feng;
Li, Hai-Tao;
Tang, Yi-qun;
An, Lu-Fan;
Huang, Wen-Long;
Peng, Si-Xun;
Hao, Xue-Mei;
Zhou, Bei-Ai;
Hu, Chai-Hong

Publication type:

Article

Exogenous hydrogen sulphide ameliorates diabetic cardiomyopathy in rats by reversing disordered calcium-handling system in sarcoplasmic reticulum.

Published in:

Journal of Pharmacy & Pharmacology, 2016, v. 68, n. 3, p. 379, doi. 10.1111/jphp.12517

By:

Cheng, Yu‐Si;
Dai, De‐Zai;
Dai, Yin;
Zhu, Dong‐Dong;
Liu, Bi‐Cheng

Publication type:

Article

CPUY11018, an azimilide derivative, ameliorates isoproterenol-induced cardiac insufficiency through relieving dysfunctional mitochondria and endoplasmic reticulum.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 8, p. 1029, doi. 10.1111/jphp.12401

By:

Li, Meng;
Tang, Yi‐Qun;
Du, Rong‐Hui;
Shi, Fang‐Hong;
Hussein, Humed Khan;
Dai, De‐Zai;
Dai, Yin

Publication type:

Article

Hypoxia alters pharmacokinetics of argirein because of mitochondrial dysfunction that is alleviated by apocynin.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 9, p. 1360, doi. 10.1111/jphp.12098

By:

Zhang, Yu‐Mao;
Yu, Feng;
Dai, De‐Zai;
Gao, Jie;
Cong, Xiao‐Dong;
Dai, Yin

Publication type:

Article

Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 6, p. 916, doi. 10.1111/jphp.12051

By:

Shi, Fang‐Hong;
Wu, You;
Dai, De‐Zai;
Cong, Xiao‐Dong;
Zhang, Yu‐Mao;
Dai, Yin

Publication type:

Article

Argirein alleviates corpus cavernosum dysfunction by suppressing pro-inflammatory factors p66Shc and ER stress chaperone Bip in diabetic rats.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 1, p. 94, doi. 10.1111/j.2042-7158.2012.01565.x

By:

Cheng, Yu‐Si;
Cong, Xiao‐Dong;
Dai, De‐Zai;
Zhang, Yun;
Dai, Yin

Publication type:

Article

Activation of AQP4, p66Shc and endoplasmic reticulum stress is involved in inflammation by carrageenan and is suppressed by argirein, a derivative of rhein.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 8, p. 1138, doi. 10.1111/j.2042-7158.2012.01507.x

By:

Cong, Xiao-Dong;
Wu, You;
Dai, De-Zai;
Ding, Ming-Jian;
Zhang, Yun;
Dai, Yin

Publication type:

Article

Comparison of sildenafil with strontium fructose diphosphate in improving erectile dysfunction against upregulated cavernosal NADPH oxidase, protein kinase C ε, and endothelin system in diabetic rats.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 2, p. 244, doi. 10.1111/j.2042-7158.2011.01390.x

By:

Xu, Ming;
Tang, Yi-Qun;
Dai, De-Zai;
Zheng, Yu-Feng;
Cheng, Yu-Si;
Zhang, Qi;
Dai, Yin

Publication type:

Article

Sildenafil improves diabetic vascular activity through suppressing endothelin receptor A, iNOS and NADPH oxidase which is comparable with the endothelin receptor antagonist CPU0213 in STZ-injected rats.

Published in:

Journal of Pharmacy & Pharmacology, 2011, v. 63, n. 7, p. 943, doi. 10.1111/j.2042-7158.2011.01268.x

By:

Luo, Lu;
Dai, De-Zai;
Cheng, Yu-Si;
Zhang, Qi;
Yuan, Wen-Jun;
Dai, Yin

Publication type:

Article

NaHS ameliorates diabetic vascular injury by correcting depressed connexin 43 and 40 in the vasculature in streptozotocin-injected rats.

Published in:

Journal of Pharmacy & Pharmacology, 2010, v. 62, n. 5, p. 615, doi. 10.1211/jpp.62.05.0009

By:

Zheng, Yu-Fen;
Dai, De-Zai;
Dai, Yin

Publication type:

Article

CPU228, a derivative of dofetilide, relieves cardiac dysfunction by normalizing FKBP12.6, NADPH oxidase and protein kinase C ε in the myocardium.

Published in:

Journal of Pharmacy & Pharmacology, 2010, v. 62, n. 1, p. 77, doi. 10.1211/jpp.62.01.0008

By:

Hamed, Khan Hussien;
Hu, Chen;
Dai, De-Zai;
Yu, Feng;
Dai, Yin

Publication type:

Article

Reduction in the Sodium Currents in Isolated Ventricular Myocytes of Guinea Pigs Treated by Chronic L-Thyroxin Medication.

Published in:

Journal of Cardiac Surgery, 2002, v. 17, n. 6, p. 563, doi. 10.1046/j.1540-8191.2002.101415.x

By:

Ma, Yu-Ping;
Hao, Xue-Mei;
Zhang, Guang-Qing;
Zhang, Pei-Ai;
Wu, Cai-Hong;
Dai, De-Zai

Publication type:

Article

Matrix is the site of indirect effects of propranolol on the ion channelopathies in cardiac remodeling by L-thyroxine.

Published in:

2002

By:

Dai, De-Zai;
Wang, Hong-Lan;
Zhang, Guang-Qin;
He, Gou-Xing;
Chen, Li

Publication type:

journal article