Works by D’Alessio, David

Results: 172

Efficacy and Safety of the Glucagon Receptor Antagonist RVT-1502 in Type 2 Diabetes Uncontrolled on Metformin Monotherapy: A 12-Week Dose-Ranging Study.

Published in:

2020

By:

Pettus, Jeremy H.;
D’Alessio, David;
Frias, Juan P.;
Vajda, Eric G.;
Pipkin, James D.;
Rosenstock, Julio;
Williamson, Gretchen;
Zangmeister, Miriam A.;
Lin Zhi;
Marschke, Keith B.;
D'Alessio, David;
Zhi, Lin

Publication type:

journal article

Metformin Use May Moderate the Effect of DPP-4 Inhibitors on Cardiovascular Outcomes.

Published in:

2017

By:

Crowley, Matthew J.;
Williams Jr., John W.;
Kosinski, Andrzej S.;
D’Alessio, David A.;
Buse, John B.;
Williams, John W Jr;
D'Alessio, David A

Publication type:

journal article

A look at duodenal mucosal resurfacing: Rationale for targeting the duodenum in type 2 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 6, p. 2017, doi. 10.1111/dom.15533

By:

Hoyt, Jonah A.;
Cozzi, Emily;
D'Alessio, David A.;
Thompson, Chris C.;
Aroda, Vanita R.

Publication type:

Article

Role of vagal activation in postprandial glucose metabolism after gastric bypass in individuals with and without hypoglycaemia.

Published in:

Diabetes, Obesity & Metabolism, 2019, v. 21, n. 6, p. 1513, doi. 10.1111/dom.13676

By:

Salehi, Marzieh;
D'Alessio, David A.;
Gastaldelli, Amalia

Publication type:

Article

Beta‐cell sensitivity to glucose is impaired after gastric bypass surgery.

Published in:

Diabetes, Obesity & Metabolism, 2018, v. 20, n. 4, p. 872, doi. 10.1111/dom.13165

By:

Salehi, Marzieh;
D'Alessio, David A.;
Gastaldelli, Amalia

Publication type:

Article

Glucagon receptor as a drug target: A witches' brew of eye of newt (peptides) and toe of frog (receptors).

Published in:

Diabetes, Obesity & Metabolism, 2018, v. 20, n. 2, p. 233, doi. 10.1111/dom.13102

By:

Nunez, Derek J.;
D'Alessio, David

Publication type:

Article

Baseline factors associated with glycaemic response to treatment with once-weekly dulaglutide in patients with type 2 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2016, v. 18, n. 11, p. 1138, doi. 10.1111/dom.12702

By:

Wysham, Carol;
Guerci, Bruno;
D'Alessio, David;
Jia, Nan;
Botros, Fady T.

Publication type:

Article

ENEMY IMAGES IN AMERICAN HISTORY (Book).

Published in:

1999

By:

Alessio, Dominic David

Publication type:

Book Review

Disruption of Glucagon-Like Peptide 1 Signaling in Sim1 Neurons Reduces Physiological and Behavioral Reactivity to Acute and Chronic Stress.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 1, p. 184, doi. 10.1523/jneurosci.1104-16.2017

By:

Ghosal, Sriparna;
Packard, Amy E. B.;
Mahbod, Parinaz;
McKlveen, Jessica M.;
Seeley, Randy J.;
Myers, Brent;
Ulrich-Lai, Yvonne;
Smith, Eric P.;
D’Alessio, David A.;
Herman, James P.

Publication type:

Article

Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction.

Published in:

Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01604-7

By:

Nauck, Michael A.;
D'Alessio, David A.

Publication type:

Article

Transitioning to active-controlled trials to evaluate cardiovascular safety and efficacy of medications for type 2 diabetes.

Published in:

Cardiovascular Diabetology, 2022, n. 1, p. 1, doi. 10.1186/s12933-022-01601-w

By:

McGuire, Darren K.;
D’Alessio, David;
Nicholls, Stephen J.;
Nissen, Steven E.;
Riesmeyer, Jeffrey S.;
Pavo, Imre;
Sethuraman, Shanthi;
Heilmann, Cory R.;
Kaiser, John J.;
Weerakkody, Govinda J.

Publication type:

Article

High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2008, v. 23, n. 1, p. 1, doi. 10.1002/hup.899

By:

Guerdjikova, Anna I.;
Mcelroy, Susan L.;
Kotwal, Renu;
Welge, Jeffrey A.;
Nelson, Erik;
Lake, Katie;
D'Alessio, David;
Keck Jr., Paul E.;
Hudson, James I.

Publication type:

Article

Vertical sleeve gastrectomy associates with airway hyperresponsiveness in a murine model of allergic airway disease and obesity.

Published in:

Frontiers in Endocrinology, 2023, v. 14, p. 1, doi. 10.3389/fendo.2023.1092277

By:

Womble, Jack T.;
Ihrie, Mark D.;
McQuade, Victoria L.;
Hegde, Akhil;
McCravy, Matthew S.;
Phatak, Sanat;
Tighe, Robert M.;
Que, Loretta G.;
D’Alessio, David;
Walker, Julia K. L.;
Ingram, Jennifer L.

Publication type:

Article

Is GLP-1 a hormone: Whether and When?

Published in:

Journal of Diabetes Investigation, 2016, v. 7, p. 50, doi. 10.1111/jdi.12466

By:

D'Alessio, David

Publication type:

Article

A Special Thanks to Lyn Reynolds, Director of the ADA Editorial Office, as She Embarks on Her Retirement.

Published in:

Diabetes Spectrum, 2022, v. 35, n. 3, p. 320, doi. 10.2337/ds22-0041

By:

Riddle, Matthew C.;
D'Alessio, David A.;
Brunton, Stephen A.;
Triplitt, Curtis L.

Publication type:

Article

Utilizing the GLP-1 signaling system to treat diabetes: Sorting through the pharmacologic approaches.

Published in:

Current Diabetes Reports, 2005, v. 5, n. 5, p. 346, doi. 10.1007/s11892-005-0092-2

By:

D’Alessio, David;
Vahl, Torsten

Publication type:

Article

CNS Glucagon-Like Peptide-1 Receptors Mediate Endocrine and Anxiety Responses to Interoceptive and Psychogenic Stressors.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 15, p. 6163, doi. 10.1523/JNEUROSCI.23-15-06163.2003

By:

Kinzig, Kimberly P.;
D'Alessio, David A.;
Herman, James P.;
Sakai, Randall R.;
Vahl, Torsten P.;
Figueredo, Helmer F.;
Murphy, Erin K.;
Seeley, Randy J.

Publication type:

Article

NIDDK at 75 Years of Age: Great Triumphs but Concerns for Its Longevity.

Published in:

2025

By:

Kahn, Steven E.;
Anderson, Cheryl A.M.;
Buse, John B.;
Selvin, Elizabeth;
D'Alessio, David A.

Publication type:

Editorial

The Development of Glucagon-Like Peptide 1 as a Therapeutic: The Triumph of the Lasker Award for Obesity Is a Victory for Diabetes Research.

Published in:

2025

By:

D'Alessio, David A.;
Kahn, Steven E.

Publication type:

Editorial

The Gut Microbiota and Diabetes: Clarity on an Emerging Topic and Introduction to a New Partnership and Journal Feature.

Published in:

2024

By:

D'Alessio, David A.;
Kahn, Steven E.;
Mulder, Hindrik

Publication type:

Editorial

A Special Thanks to Lyn Reynolds, Director of the ADA Editorial Office, as She Embarks on Her Retirement.

Published in:

Diabetes Care, 2022, v. 45, n. 8, p. 1707, doi. 10.2337/dc22-en08

By:

Riddle, Matthew C.;
D'Alessio, David A.;
Brunton, Stephen A.;
Triplitt, Curtis L.

Publication type:

Article

A Lesson From 2020: Public Health Matters for Both COVID-19 and Diabetes.

Published in:

2021

By:

Riddle, Matthew C.;
Bakris, George;
Blonde, Lawrence;
Boulton, Andrew J.M.;
D'Alessio, David;
DiMeglio, Linda A.;
Gonder-Frederick, Linda;
Hood, Korey K.;
Hu, Frank B.;
Kahn, Steven E.;
Kaul, Sanjay;
Leiter, Lawrence A.;
Moses, Robert G.;
Rich, Stephen S.;
Rosenstock, Julio;
Wylie-Rosett, Judith

Publication type:

Editorial

Erratum. 2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2020;43:487-493.

Published in:

2020

By:

Buse, John B.;
Wexler, Deborah J.;
Tsapas, Apostolos;
Rossing, Peter;
Mingrone, Geltrude;
Mathieu, Chantal;
D'Alessio, David A.;
Davies, Melanie J.

Publication type:

journal article

2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

Published in:

2020

By:

Buse, John B.;
Wexler, Deborah J.;
Tsapas, Apostolos;
Rossing, Peter;
Mingrone, Geltrude;
Mathieu, Chantal;
D'Alessio, David A.;
Davies, Melanie J.

Publication type:

journal article

Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

Published in:

2018

By:

Davies, Melanie J.;
D'Alessio, David A.;
Fradkin, Judith;
Kernan, Walter N.;
Mathieu, Chantal;
Mingrone, Geltrude;
Rossing, Peter;
Tsapas, Apostolos;
Wexler, Deborah J.;
Buse, John B.

Publication type:

journal article

Can We RISE to the Challenge of Youth-Onset Type 2 Diabetes?

Published in:

2018

By:

Buse, John B.;
D'Alessio, David A.;
Riddle, Matthew C.

Publication type:

journal article

Big Topics for in 2018: Clinical Guidelines, Costs of Diabetes, and Information Technology.

Published in:

Diabetes Care, 2018, v. 41, n. 7, p. 1327, doi. 10.2337/dci18-0035

By:

Riddle, Matthew C.;
Bakris, George;
Boulton, Andrew J. M.;
Blonde, Lawrence;
D'Alessio, David;
Greene, Eddie L.;
de Groot, Mary;
Hood, Korey;
Hu, Frank B.;
Kahn, Steven E.;
Kaul, Sanjay;
Le Roith, Derek;
Moses, Robert G.;
Rich, Stephen S.;
Rosenstock, Julio;
Tamborlane, William V.;
Wylie-Rosett, Judith;
Reynolds, Lyn

Publication type:

Article

Diabetes Care: "Taking It to the Limit One More Time".

Published in:

2017

By:

Cefalu, William T.;
Boulton, Andrew J. M.;
Tamborlane, William V.;
Moses, Robert G.;
LeRoith, Derek;
Greene, Eddie L.;
Hu, Frank B.;
Bakris, George;
Wylie-Rosett, Judith;
Rosenstock, Julio;
Kahn, Steven E.;
Weinger, Katie;
Blonde, Lawrence;
de Groot, Mary;
Rich, Stephen;
D'Alessio, David;
Reynolds, Lyn;
Riddle, Matthew C.

Publication type:

Editorial

Diabetes Care: "Lagniappe" and "Seeing Is Believing"!

Published in:

2016

By:

Cefalu, William T.;
Boulton, Andrew J. M.;
Tamborlane, William V.;
Moses, Robert G.;
LeRoith, Derek;
Greene, Eddie L.;
Hu, Frank B.;
Bakris, George;
Wylie-Rosett, Judith;
Rosenstock, Julio;
Weinger, Katie;
Blonde, Lawrence;
de Groot, Mary;
Rich, Stephen S.;
D'Alessio, David;
Riddle, Matthew C.;
Reynolds, Lyn

Publication type:

Editorial

Bariatric Surgery: A Potential Treatment for Type 2 Diabetes in Youth.

Published in:

2016

By:

Shah, Amy S.;
D'Alessio, David;
Ford-Adams, Martha E.;
Desai, Ashish P.;
Inge, Thomas H.

Publication type:

journal article

Building Momentum: Taking on the Real “Issues” of Diabetes Care!

Published in:

2016

By:

Cefalu, William T.;
Boulton, Andrew J. M.;
Tamborlane, William V.;
Moses, Robert G.;
LeRoith, Derek;
Greene, Eddie L.;
Hu, Frank B.;
Bakris, George;
Wylie-Rosett, Judith;
Rosenstock, Julio;
Weinger, Katie;
Blonde, Lawrence;
de Groot, Mary;
Riddle, Matthew C.;
Golden, Sherita Hill;
Rich, Stephen S.;
D'Alessio, David;
Reynolds, Lyn;
Hill Golden, Sherita

Publication type:

research

One small step for mice, one giant leap for GWAS?

Published in:

2019

By:

Herman, Mark A.;
Campbell, Jonathan E.;
D'Alessio, David A.

Publication type:

journal article

DREADDing proglucagon neurons: a fresh look at metabolic regulation by the brain.

Published in:

2017

By:

Campbell, Jonathan E.;
D'Alessio, David A.

Publication type:

journal article

Ghrelin and hypothalamic development: too little and too much of a good thing.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 490, doi. 10.1172/JCI79187

By:

Tong, Jenny;
D'Alessio, David

Publication type:

Article

Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2456, doi. 10.1172/JCI72434

By:

Sisley, Stephanie;
Gutierrez-Aguilar, Ruth;
Scott, Michael;
D'Alessio, David A.;
Sandoval, Darleen A.;
Seeley, Randy J.

Publication type:

Article

New ways in which GLP-1 can regulate glucose homeostasis.

Published in:

Journal of Clinical Investigation, 2005, v. 115, n. 12, p. 3406, doi. 10.1172/JCI27207

By:

D'Alessio, David A.;
Sandoval, Darleen A.;
Seeley, Randy J.

Publication type:

Article

Bariatric/metabolic surgery for diabetes: Incorporating a powerful treatment into standard care.

Published in:

2016

By:

Wolfe, Bruce M.;
D'Alessio, David A.

Publication type:

Editorial

Gastric bypass alters both glucose-dependent and glucose-independent regulation of islet hormone secretion.

Published in:

2015

By:

Salehi, Marzieh;
Woods, Stephen C.;
D'Alessio, David A.

Publication type:

journal article

Adiponectin Changes in Relation to the Macronutrient Composition of a Weight-Loss Diet.

Published in:

Obesity (19307381), 2011, v. 19, n. 11, p. 2198, doi. 10.1038/oby.2011.60

By:

Summer, Suzanne S.;
Brehm, Bonnie J.;
Benoit, Stephen C.;
D'Alessio, David A.

Publication type:

Article

Bypassing the Duodenum Does Not Improve Insulin Resistance Associated With Diet-Induced Obesity in Rodents.

Published in:

Obesity (19307381), 2011, v. 19, n. 2, p. 380, doi. 10.1038/oby.2010.263

By:

Kindel, Tammy L.;
Martins, Paulo J. F.;
Yoder, Stephanie M.;
Jandacek, Ronald J.;
Seeley, Randy J.;
D'Alessio, David A.;
Obici, Silvana;
Tso, Patrick

Publication type:

Article

Food Intake-independent Effects of CB1 Antagonism on Glucose and Lipid Metabolism.

Published in:

Obesity (19307381), 2009, v. 17, n. 8, p. 1641, doi. 10.1038/oby.2009.84

By:

Cota, Daniela;
Sandoval, Darleen A.;
Olivieri, Massimiliano;
Prodi, Elena;
D'Alessio, David A.;
Woods, Stephen C.;
Seeley, Randy J.;
Obici, Silvana

Publication type:

Article

The effect of chronic twice daily exenatide treatment on β-cell function in new onset type 2 diabetes.

Published in:

Clinical Endocrinology, 2014, v. 80, n. 4, p. 545, doi. 10.1111/cen.12199

By:

Gastaldelli, Amalia;
Brodows, Robert G.;
D'Alessio, David

Publication type:

Article

Intestinal Hormones and Regulation of Satiety: The Case for CCK, GLP-1, PYY, and Apo A-IV.

Published in:

JPEN Journal of Parenteral & Enteral Nutrition, 2008, v. 32, n. 5, p. 567, doi. 10.1177/0148607108322401

By:

D'Alessio, David

Publication type:

Article

Sequential Intensification of Metformin Treatment in Type 2 Diabetes With Liraglutide Followed by Randomized Addition of Basal Insulin Prompted by A1C Targets.

Published in:

Diabetes Care, 2012, v. 35, n. 7, p. 1446, doi. 10.2337/dc11-1928

By:

Devries, J. Hans;
Bain, Stephen C.;
Rodbard, Helena W.;
Seufert, Jochen;
D'Alessio, David;
Thomsen, Anne B.;
Zychma, Marcin;
Rosenstock, Julio

Publication type:

Article

One-Year Comparison of a High-Monounsaturated Fat Diet With a High-Carbohydrate Diet in Type 2 Diabetes.

Published in:

Diabetes Care, 2009, v. 32, n. 2, p. 215, doi. 10.2337/dc08-0687

By:

Brehm, Bonnie J.;
Lattin, Barbara L.;
Summer, Suzanne S.;
Borack, Jane A.;
Gilchrist, Gina M.;
Jandacek, Ronald J.;
D'alessio, David A.

Publication type:

Article

Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans.

Published in:

2003

By:

Quddusi, Shaista;
Vahl, Torsten P.;
Hanson, Kevin;
Prigeon, Ronald L.;
D'alessio, David A.

Publication type:

journal article

Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease.

Published in:

Metabolomics, 2020, v. 16, n. 7, p. 1, doi. 10.1007/s11306-020-01696-w

By:

Chatterjee, Ranee;
Davenport, Clemontina A.;
Kwee, Lydia;
D'Alessio, David;
Svetkey, Laura P.;
Lin, Pao-Hwa;
Slentz, Cris A.;
Ilkayeva, Olga;
Johnson, Johanna;
Edelman, David;
Shah, Svati H.

Publication type:

Article

The Effect of Duodenal–Jejunal Bypass on Glucose-Dependent Insulinotropic Polypeptide Secretion in Wistar Rats.

Published in:

Obesity Surgery, 2010, v. 20, n. 6, p. 768, doi. 10.1007/s11695-010-0095-1

By:

Kindel, Tammy L.;
Yoder, Stephanie M.;
D'Alessio, David A.;
Tso, Patrick

Publication type:

Article

Ghrelin Enhances Olfactory Sensitivity and Exploratory Sniffing in Rodents and Humans.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 15, p. 5841, doi. 10.1523/JNEUROSCI.5680-10.2011

By:

Tong, Jenny;
Mannea, Erica;
Aimé, Pascaline;
Pfluger, Paul T.;
Chun-Xia Yi;
Castaneda, Tamara R.;
Davis, Harold W.;
Xueying Ren;
Pixley, Sarah;
Benoit, Stephen;
Julliard, Karyne;
Woods, Stephen C.;
Horvath, Tamas L.;
Sleeman, Mark M.;
D'Alessio, David;
Obici, Silvana;
Frank, Robert;
Tschöp, Matthias H.

Publication type:

Article

Hyperphagia and Increased Fat Accumulation in Two Models of Chronic CNS Glucagon-Like Peptide-1 Loss of Function.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 10, p. 3904, doi. 10.1523/JNEUROSCI.2212-10.2011

By:

Barrera, Jason G.;
Jones, Kenneth R.;
Herman, James P.;
D'Alessio, David A.;
Woods, Stephen C.;
Seeley, Randy J.

Publication type:

Article