Works by D'hooghe, Matthias

Results: 39

Synthesis of the 1,5‐Benzothiazepane Scaffold – Established Methods and New Developments.

Published in:

ChemistryOpen, 2023, v. 12, n. 2, p. 1, doi. 10.1002/open.202200262

By:

Ronse, Ulrike;
Magdalenić, Katarina;
Van Camp, John;
D'hooghe, Matthias

Publication type:

Article

Expedient Synthesis of Lupulones and Their Derivatization to 2,8‐7H‐Dihydrochromen‐7‐ones.

Published in:

ChemistryOpen, 2020, v. 9, n. 4, p. 442, doi. 10.1002/open.202000008

By:

Decuyper, Lena;
Kaur, Gurkirat;
Versyck, Charlotte;
Blondeel, Eline;
Depetter, Yves;
Van Hecke, Kristof;
D'hooghe, Matthias

Publication type:

Article

Synthesis of Novel Aza‐aromatic Curcuminoids with Improved Biological Activities towards Various Cancer Cell Lines.

Published in:

ChemistryOpen, 2018, v. 7, n. 5, p. 381, doi. 10.1002/open.201800029

By:

Theppawong, Atiruj;
Van de Walle, Tim;
Grootaert, Charlotte;
Bultinck, Margot;
Desmet, Tom;
Van Camp, John;
D'hooghe, Matthias

Publication type:

Article

Synthetic Approaches toward Monocyclic 3-Amino-β-lactams.

Published in:

ChemistryOpen, 2017, v. 6, n. 3, p. 301, doi. 10.1002/open.201700051

By:

Deketelaere, Sari;
Van NguyEN, TuyEN;
StevENs, Christian V.;
D'hooghe, Matthias

Publication type:

Article

Synthesis and Cancer Cell Cytotoxicity of 6‐, 7‐, or 8‐Substituted 2‐(Hetero)aryl‐4‐(4‐(Hetero)aryl‐2‐Oxobut‐3‐en‐1‐Ylidene)Benzothiazepanes.

Published in:

Journal of Heterocyclic Chemistry, 2025, v. 62, n. 2, p. 249, doi. 10.1002/jhet.4936

By:

Magdalenic, Katarina;
Morillon, Donatien;
De Jonghe, Steven;
Persoons, Leentje;
Schols, Dominique;
Van Hecke, Kristof;
Grootaert, Charlotte;
Van Camp, John;
D'hooghe, Matthias

Publication type:

Article

Synthesis of 4‐imidoyl‐, 4‐oxiranyl‐ and 4‐propargyloxyphenyl‐substituted β‐lactam building blocks.

Published in:

Journal of Heterocyclic Chemistry, 2023, v. 60, n. 3, p. 423, doi. 10.1002/jhet.4597

By:

Deketelaere, Sari;
Kaur, Gurkirat;
Piens, Nicola;
Deturck, Daan;
Depestel, Robin;
Van Hecke, Kristof;
Stevens, Christian V.;
Kumar, Vipan;
D'hooghe, Matthias

Publication type:

Article

Synthesis of Indoline‐Based Benzhydroxamic Acids as Potential HDAC6 Inhibitors.

Published in:

ChemistrySelect, 2019, v. 4, n. 42, p. 12308, doi. 10.1002/slct.201902042

By:

Depetter, Yves;
Geurs, Silke;
Franceus, Jorick;
Knez, Damijan;
Desmet, Tom;
De Bosscher, Karolien;
De Wever, Olivier;
Gobec, Stanislav;
D'hooghe, Matthias

Publication type:

Article

Carbonylation of Aziridines as a Powerful Tool for the Synthesis of Functionalized β-Lactams.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 40, p. 5943, doi. 10.1002/ejoc.201700698

By:

Piens, Nicola;
D'hooghe, Matthias

Publication type:

Article

LiAlH4-Induced Thia-Aza-Payne Rearrangement of Functionalized 2-(Thiocyanatomethyl)aziridines into 2-(Aminomethyl)thiiranes as an Entry to 5-(Chloromethyl)thiazolidin-2-ones.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 22, p. 3229, doi. 10.1002/ejoc.201700549

By:

Dolfen, Jeroen;
Van Hecke, Kristof;
D'hooghe, Matthias

Publication type:

Article

SYNTHESIS OF N -(4-CHLOROBUTYL)BUTANAMIDE, A CHLORINATED AMIDE ISOLATED FROM ALOE SABAEA.

Published in:

Organic Preparations & Procedures International, 2003, v. 35, n. 5, p. 501, doi. 10.1080/00304940309355861

By:

D'hooghe, Matthias;
Szakonyi, Zsolt;
Fülöp, Ferenc;
Kimpe, Norbert De

Publication type:

Article

Conjugate addition of 2-(bromomethyl)- and 2-(2-bromoethyl)-piperidine to alkyl acrylates: application towards the synthesis of 2-(methoxycarbonyl)indolizidine.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2010, p. 93

By:

D'hooghe, Matthias;
Tehrani, Kourosch Abbaspour;
Buyck, Christophe;
De Kimpe, Norbert

Publication type:

Article

α‐Unsaturated 3‐Amino‐1‐carboxymethyl‐β‐lactams as Bacterial PBP Inhibitors: Synthesis and Biochemical Assessment.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 70, p. 16128, doi. 10.1002/chem.201904139

By:

Decuyper, Lena;
Magdalenić, Katarina;
Verstraete, Marie;
Jukič, Marko;
Sosič, Izidor;
Sauvage, Eric;
Amoroso, Ana Maria;
Verlaine, Olivier;
Joris, Bernard;
Gobec, Stanislav;
D'hooghe, Matthias

Publication type:

Article

Synthesis of 1,4‐Thiazepane‐Based Curcuminoids with Promising Anticancer Activity.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 54, p. 12583, doi. 10.1002/chem.201902549

By:

Theppawong, Atiruj;
Van de Walle, Tim;
Van Hecke, Kristof;
Grootaert, Charlotte;
Van Camp, John;
D'hooghe, Matthias

Publication type:

Article

In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3‐Amino‐1‐carboxymethyl‐β‐lactams as Inhibitors of Penicillin‐Binding Proteins of Resistant Bacteria.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 57, p. 15254, doi. 10.1002/chem.201801868

By:

Decuyper, Lena;
Deketelaere, Sari;
Vanparys, Lore;
Jukič, Marko;
Sosič, Izidor;
Sauvage, Eric;
Amoroso, Ana Maria;
Verlaine, Olivier;
Joris, Bernard;
Gobec, Stanislav;
D'hooghe, Matthias

Publication type:

Article

Reactivity of 3-Oxo-β-lactams with Respect to Primary Amines-An Experimental and Computational Approach.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 71, p. 18002, doi. 10.1002/chem.201703852

By:

Piens, Nicola;
Goossens, Hannelore;
Hertsen, Dietmar;
Deketelaere, Sari;
Crul, Lieselotte;
Demeurisse, Lotte;
De Moor, Jelle;
Van den Broeck, Elias;
Mollet, Karen;
Van Hecke, Kristof;
Van Speybroeck, Veronique;
D'hooghe, Matthias

Publication type:

Article

Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane- or Cycloheptane-Annulated 1,5-Benzothiazepine Scaffold.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 1, p. 128, doi. 10.1002/chem.201604167

By:

De Vreese, Rob;
Galle, Lisa;
Depetter, Yves;
Franceus, Jorick;
Desmet, Tom;
Van Hecke, Kristof;
Benoy, Veronick;
Van Den Bosch, Ludo;
D'hooghe, Matthias

Publication type:

Article

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models.

Published in:

International Journal of Cancer, 2019, v. 145, n. 3, p. 735, doi. 10.1002/ijc.32169

By:

Depetter, Yves;
Geurs, Silke;
De Vreese, Rob;
Goethals, Sophie;
Vandoorn, Elien;
Laevens, Alien;
Steenbrugge, Jonas;
Meyer, Evelyne;
Tullio, Pascal;
Bracke, Marc;
D'hooghe, Matthias;
De Wever, Olivier

Publication type:

Article

Unexpected Formation of 2,2‐Dichloro‐N‐(chloromethyl)acetamides during Attempted Staudinger 2,2‐Dichloro‐β‐lactam Synthesis.

Published in:

European Journal of Organic Chemistry, 2021, v. 2021, n. 42, p. 5823, doi. 10.1002/ejoc.202100975

By:

Deketelaere, Sari;
Van Den Broeck, Elias;
Cools, Lore;
Deturck, Daan;
Naeyaert, Hannes;
Van Hecke, Kristof;
Stevens, Christian V.;
Van Speybroeck, Veronique;
D'hooghe, Matthias

Publication type:

Article

LiAlH4-Induced Selective Ring Rearrangement of 2-(2-Cyanoethyl)aziridines toward 2-(Aminomethyl)pyrrolidines and 3-Aminopiperidines as Eligible Heterocyclic Building Blocks.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 14, p. 4945, doi. 10.1002/chem.201504853

By:

Dolfen, Jeroen;
Vervisch, Karel;
De Kimpe, Norbert;
D'hooghe, Matthias

Publication type:

Article

Selective Synthesis of Functionalized Trifluoromethylated Pyrrolidines, Piperidines, and Azepanes Starting from 1-Tosyl-2-(trifluoromethyl)aziridine.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 34, p. 10650, doi. 10.1002/chem.201304759

By:

Dolfen, Jeroen;
Kenis, Sara;
Van Hecke, Kristof;
De Kimpe, Norbert;
D'hooghe, Matthias

Publication type:

Article

Nucleophile-Directed Selective Transformation of cis-1-Tosyl-2-tosyloxymethyl-3-(trifluoromethyl)aziridine into Aziridines, Azetidines, and Benzo-Fused Dithianes, Oxathianes, Dioxanes, and (Thio)morpholines.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 19, p. 5966, doi. 10.1002/chem.201204485

By:

Kenis, Sara;
D'hooghe, Matthias;
Verniest, Guido;
Reybroeck, Maaike;
Dang Thi, Tuyet Anh;
Pham The, Chinh;
Thi Pham, Tham;
Törnroos, Karl W.;
Van Tuyen, Nguyen;
De Kimpe, Norbert

Publication type:

Article

Synthesis of 2-Hydroxy-1,4-oxazin-3-ones through Ring Transformation of 3-Hydroxy-4-(1,2-dihydroxyethyl)-β-lactams and a Study of Their Reactivity.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 10, p. 3383, doi. 10.1002/chem.201203314

By:

Mollet, Karen;
Goossens, Hannelore;
Piens, Nicola;
Catak, Saron;
Waroquier, Michel;
Törnroos, Karl W.;
Van Speybroeck, Veronique;
D'hooghe, Matthias;
De Kimpe, Norbert

Publication type:

Article

Use of functionalized β-lactams as building blocks in heterocyclic chemistry.

Published in:

Pure & Applied Chemistry, 2010, v. 82, n. 9, p. 1749, doi. 10.1351/PAC-CON-09-09-39

By:

Matthias D'hooghe;
Stijn Dekeukeleire;
Leemans, Erika;
Kimpe, Norbert De

Publication type:

Article

Synthesis of Pyrrolidine‐fused β‐lactams as Potential β‐lactamase Inhibitors.

Published in:

Asian Journal of Organic Chemistry, 2024, v. 13, n. 11, p. 1, doi. 10.1002/ajoc.202400364

By:

Deketelaere, Sari;
Díez‐Poza, Carlos;
Aelbrecht, Margot;
Mortier, Jonas;
Van Den Bossche, Bram;
Franceus, Jorick;
Desmet, Tom;
Van Hecke, Kristof;
Stevens, Christian V.;
D'hooghe, Matthias

Publication type:

Article

Synthesis and Applications of 3-Methylene-4- (trifluoromethyl)azetidin-2-ones as Building Blocks for the Preparation of Mono- and Spirocyclic 4-CF3-β-Lactams.

Published in:

Asian Journal of Organic Chemistry, 2016, v. 5, n. 12, p. 1480, doi. 10.1002/ajoc.201600387

By:

Dao Thi, Hang;
Danneels, Barbara;
Desmet, Tom;
Van Hecke, Kristof;
Van NguyEN, TuyEN;
D'hooghe, Matthias

Publication type:

Article

Synthesis and Penicillin‐binding Protein Inhibitory Assessment of Dipeptidic 4‐Phenyl‐β‐lactams from α‐Amino Acid‐derived Imines.

Published in:

Chemistry - An Asian Journal, 2020, v. 15, n. 1, p. 51, doi. 10.1002/asia.201901470

By:

Decuyper, Lena;
Jukič, Marko;
Sosič, Izidor;
Amoroso, Ana Maria;
Verlaine, Olivier;
Joris, Bernard;
Gobec, Stanislav;
D'hooghe, Matthias

Publication type:

Article

Formation of Fluorinated Amido Esters through Unexpected C3−C4 Bond Fission in 4‐Trifluoromethyl‐3‐oxo‐β‐lactams.

Published in:

Chemistry - An Asian Journal, 2018, v. 13, n. 4, p. 421, doi. 10.1002/asia.201701636

By:

Dao Thi, Hang;
Goossens, Hannelore;
Hertsen, Dietmar;
Otte, Valerie;
Van Nguyen, Tuyen;
Van Speybroeck, Veronique;
D'hooghe, Matthias

Publication type:

Article

Nucleophile-Dependent Regio- and Stereoselective Ring Opening of 1-Azoniabicyclo[3.1.0]hexane Tosylate.

Published in:

Chemistry - An Asian Journal, 2014, v. 9, n. 4, p. 1060, doi. 10.1002/asia.201301551

By:

Ji, Mi ‐ Kyung;
Hertsen, Dietmar;
Yoon, Doo ‐ Ha;
Eum, Heesung;
Goossens, Hannelore;
Waroquier, Michel;
Van Speybroeck, Veronique;
D'hooghe, Matthias;
De Kimpe, Norbert;
Ha, Hyun ‐ Joon

Publication type:

Article

Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry - Preparation and Synthetic Application of 1-Azoniabicyclo[n.1.0]alkanes.

Published in:

Advanced Synthesis & Catalysis, 2016, v. 358, n. 22, p. 3485, doi. 10.1002/adsc.201600750

By:

Dolfen, Jeroen;
Yadav, Nagendra Nath;
De Kimpe, Norbert;
D'hooghe, Matthias;
Ha, Hyun ‐ Joon

Publication type:

Article

Front Cover Picture: Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry - Preparation and Synthetic Application of 1-Azoniabicyclo[n.1.0]alkanes (Adv. Synth. Catal. 22/2016).

Published in:

Advanced Synthesis & Catalysis, 2016, v. 358, n. 22, p. 3483, doi. 10.1002/adsc.201601081

By:

Dolfen, Jeroen;
Yadav, Nagendra Nath;
De Kimpe, Norbert;
D'hooghe, Matthias;
Ha, Hyun ‐ Joon

Publication type:

Article

Antibacterial and β‐Lactamase Inhibitory Activity of Monocyclic β‐Lactams.

Published in:

Medicinal Research Reviews, 2018, v. 38, n. 2, p. 426, doi. 10.1002/med.21443

By:

Decuyper, Lena;
Jukič, Marko;
Sosič, Izidor;
Žula, Aleš;
D'hooghe, Matthias;
Gobec, Stanislav

Publication type:

Article

High-yield synthesis of 2-O-α-d-glucosyl-d-glycerate by a bifunctional glycoside phosphorylase.

Published in:

Applied Microbiology & Biotechnology, 2024, v. 108, n. 1, p. 1, doi. 10.1007/s00253-023-12970-x

By:

Franceus, Jorick;
Steynen, Manon;
Allaert, Yentl;
Bredael, Kato;
D'hooghe, Matthias;
Desmet, Tom

Publication type:

Article

High-yield synthesis of 2-O-α-d-glucosyl-d-glycerate by a bifunctional glycoside phosphorylase.

Published in:

Applied Microbiology & Biotechnology, 2024, v. 108, n. 1, p. 1, doi. 10.1007/s00253-023-12970-x

By:

Franceus, Jorick;
Steynen, Manon;
Allaert, Yentl;
Bredael, Kato;
D’hooghe, Matthias;
Desmet, Tom

Publication type:

Article

Highly Stereoselective Synthesis of β-Lactams Utilizing α-Chloroimines as New and Powerful Chiral Inductors.

Published in:

Chemistry - A European Journal, 2008, v. 14, n. 21, p. 6336, doi. 10.1002/chem.200800845

By:

D'hooghe, Matthias;
Van Brabandt, Willem;
Dekeukeleire, Stijn;
Dejaegher, Yves;
De Kimpe, Norbert

Publication type:

Article

Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties.

Published in:

Journal of Chemistry, 2022, p. 1, doi. 10.1155/2022/2164558

By:

Bredael, Kato;
Geurs, Silke;
Clarisse, Dorien;
De Bosscher, Karolien;
D'hooghe, Matthias

Publication type:

Article

Synthesis and Antibacterial Properties of 3‐Amino‐β‐Lactams Bearing a Heteroatom‐Containing C4 Substituent.

Published in:

ChemMedChem, 2025, v. 20, n. 9, p. 1, doi. 10.1002/cmdc.202400994

By:

Bredael, Kato;
Vanhecke, Fien;
Vandenheede, Emma;
Stevens, Christian V.;
Gobec, Stanislav;
D'hooghe, Matthias

Publication type:

Article

Synthesis of Novel Nitroxoline Analogs with Potent Cathepsin B Exopeptidase Inhibitory Activity.

Published in:

ChemMedChem, 2020, v. 15, n. 24, p. 2477, doi. 10.1002/cmdc.202000402

By:

Van de Walle, Tim;
Briand, Marina;
Mitrović, Ana;
Sosič, Izidor;
Gobec, Stanislav;
Kos, Janko;
Persoons, Leentje;
Daelemans, Dirk;
De Jonghe, Steven;
Ubiparip, Zorica;
Desmet, Tom;
Van Hecke, Kristof;
Mangelinckx, Sven;
D'hooghe, Matthias

Publication type:

Article

Electrophilic Bromination in Flow: A Safe and Sustainable Alternative to the Use of Molecular Bromine in Batch.

Published in:

Molecules, 2019, v. 24, n. 11, p. 2116, doi. 10.3390/molecules24112116

By:

Van Kerrebroeck, Reinout;
Naert, Pieter;
Heugebaert, Thomas S. A.;
D'hooghe, Matthias;
Stevens, Christian V.;
Benaglia, Maurizio;
Pericàs, Miquel A.

Publication type:

Article

Engineering Comamonas testosteroni for the production of 2-pyrone-4,6-dicarboxylic acid as a promising building block.

Published in:

Microbial Cell Factories, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12934-023-02202-2

By:

Delmulle, Tom;
Bovijn, Stijn;
Deketelaere, Sari;
Castelein, Martijn;
Erauw, Tom;
D'hooghe, Matthias;
Soetaert, Wim K.

Publication type:

Article

Works by D'hooghe, Matthias

Synthesis of the 1,5‐Benzothiazepane Scaffold – Established Methods and New Developments.

Expedient Synthesis of Lupulones and Their Derivatization to 2,8‐7H‐Dihydrochromen‐7‐ones.

Synthesis of Novel Aza‐aromatic Curcuminoids with Improved Biological Activities towards Various Cancer Cell Lines.

Synthetic Approaches toward Monocyclic 3-Amino-β-lactams.

Synthesis and Cancer Cell Cytotoxicity of 6‐, 7‐, or 8‐Substituted 2‐(Hetero)aryl‐4‐(4‐(Hetero)aryl‐2‐Oxobut‐3‐en‐1‐Ylidene)Benzothiazepanes.

Synthesis of 4‐imidoyl‐, 4‐oxiranyl‐ and 4‐propargyloxyphenyl‐substituted β‐lactam building blocks.

Synthesis of Indoline‐Based Benzhydroxamic Acids as Potential HDAC6 Inhibitors.

Carbonylation of Aziridines as a Powerful Tool for the Synthesis of Functionalized β-Lactams.

LiAlH<sub>4</sub>-Induced Thia-Aza-Payne Rearrangement of Functionalized 2-(Thiocyanatomethyl)aziridines into 2-(Aminomethyl)thiiranes as an Entry to 5-(Chloromethyl)thiazolidin-2-ones.

SYNTHESIS OF N -(4-CHLOROBUTYL)BUTANAMIDE, A CHLORINATED AMIDE ISOLATED FROM ALOE SABAEA.

Conjugate addition of 2-(bromomethyl)- and 2-(2-bromoethyl)-piperidine to alkyl acrylates: application towards the synthesis of 2-(methoxycarbonyl)indolizidine.

α‐Unsaturated 3‐Amino‐1‐carboxymethyl‐β‐lactams as Bacterial PBP Inhibitors: Synthesis and Biochemical Assessment.

Synthesis of 1,4‐Thiazepane‐Based Curcuminoids with Promising Anticancer Activity.

In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3‐Amino‐1‐carboxymethyl‐β‐lactams as Inhibitors of Penicillin‐Binding Proteins of Resistant Bacteria.

Reactivity of 3-Oxo-β-lactams with Respect to Primary Amines-An Experimental and Computational Approach.

Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane- or Cycloheptane-Annulated 1,5-Benzothiazepine Scaffold.

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models.

Unexpected Formation of 2,2‐Dichloro‐N‐(chloromethyl)acetamides during Attempted Staudinger 2,2‐Dichloro‐β‐lactam Synthesis.

LiAlH<sub>4</sub>-Induced Selective Ring Rearrangement of 2-(2-Cyanoethyl)aziridines toward 2-(Aminomethyl)pyrrolidines and 3-Aminopiperidines as Eligible Heterocyclic Building Blocks.

Selective Synthesis of Functionalized Trifluoromethylated Pyrrolidines, Piperidines, and Azepanes Starting from 1-Tosyl-2-(trifluoromethyl)aziridine.

Nucleophile-Directed Selective Transformation of cis-1-Tosyl-2-tosyloxymethyl-3-(trifluoromethyl)aziridine into Aziridines, Azetidines, and Benzo-Fused Dithianes, Oxathianes, Dioxanes, and (Thio)morpholines.

Synthesis of 2-Hydroxy-1,4-oxazin-3-ones through Ring Transformation of 3-Hydroxy-4-(1,2-dihydroxyethyl)-β-lactams and a Study of Their Reactivity.

Use of functionalized β-lactams as building blocks in heterocyclic chemistry.

Synthesis of Pyrrolidine‐fused β‐lactams as Potential β‐lactamase Inhibitors.

Synthesis and Applications of 3-Methylene-4- (trifluoromethyl)azetidin-2-ones as Building Blocks for the Preparation of Mono- and Spirocyclic 4-CF<sub>3</sub>-β-Lactams.

Synthesis and Penicillin‐binding Protein Inhibitory Assessment of Dipeptidic 4‐Phenyl‐β‐lactams from α‐Amino Acid‐derived Imines.

Formation of Fluorinated Amido Esters through Unexpected C3−C4 Bond Fission in 4‐Trifluoromethyl‐3‐oxo‐β‐lactams.

Nucleophile-Dependent Regio- and Stereoselective Ring Opening of 1-Azoniabicyclo[3.1.0]hexane Tosylate.

Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry - Preparation and Synthetic Application of 1-Azoniabicyclo[n.1.0]alkanes.

Front Cover Picture: Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry - Preparation and Synthetic Application of 1-Azoniabicyclo[n.1.0]alkanes (Adv. Synth. Catal. 22/2016).

Antibacterial and β‐Lactamase Inhibitory Activity of Monocyclic β‐Lactams.

High-yield synthesis of 2-O-α-d-glucosyl-d-glycerate by a bifunctional glycoside phosphorylase.

High-yield synthesis of 2-O-α-d-glucosyl-d-glycerate by a bifunctional glycoside phosphorylase.

Highly Stereoselective Synthesis of β-Lactams Utilizing α-Chloroimines as New and Powerful Chiral Inductors.

Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties.

Synthesis and Antibacterial Properties of 3‐Amino‐β‐Lactams Bearing a Heteroatom‐Containing C4 Substituent.

Synthesis of Novel Nitroxoline Analogs with Potent Cathepsin B Exopeptidase Inhibitory Activity.

Electrophilic Bromination in Flow: A Safe and Sustainable Alternative to the Use of Molecular Bromine in Batch.

Engineering Comamonas testosteroni for the production of 2-pyrone-4,6-dicarboxylic acid as a promising building block.