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Fetal bovine serum, but not human serum, inhibits the in vitro cytotoxicity of ET-743 (Yondelis, trabectedin), an example of potential problems for extrapolation of active drug concentrations from in vitro studies.
- Published in:
- 2004
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- Publication type:
- journal article
Prompt detection of L-asparaginase inactivation is crucial to optimize treatment efficacy also in aggressive lymphomas.
- Published in:
- 2018
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- Publication type:
- Case Study
Phase I and Clinical Pharmacological Evaluation of Aphidicolin Glycinate.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1991, v. 83, n. 16, p. 1160, doi. 10.1093/jnci/83.16.1160
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- Publication type:
- Article
Induction of Partial Synchronization of Leukemia Cells by Continuous Infusion of Low-Dose Methotrexate Followed by Citrovorum Factor.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1989, v. 81, n. 19, p. 1509
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- Publication type:
- Article
Inhibition of tumor‐associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti‐PD‐1 therapy.
- Published in:
- European Journal of Immunology, 2021, v. 51, n. 11, p. 2677, doi. 10.1002/eji.202149379
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- Publication type:
- Article
DNA Damage Response and Immune Defense.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7504, doi. 10.3390/ijms21207504
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- Publication type:
- Article
Clinical and pathological factors influencing survival in a large cohort of triple-negative breast cancer patients.
- Published in:
- 2018
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- Publication type:
- journal article
MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis.
- Published in:
- 2017
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- Publication type:
- journal article
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.
- Published in:
- 2007
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- Publication type:
- journal article
An integrated approach for the systematic evaluation of polymeric nanoparticles in healthy and diseased organisms.
- Published in:
- Journal of Nanoparticle Research, 2014, v. 16, n. 7, p. 1, doi. 10.1007/s11051-014-2481-4
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- Publication type:
- Article
The Neuroprotective Effect of Erythropoietin in Docetaxel-Induced Peripheral Neuropathy Causes No Reduction of Antitumor Activity in 13762 Adenocarcinoma-Bearing Rats.
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- Neurotoxicity Research, 2010, v. 18, n. 2, p. 151, doi. 10.1007/s12640-009-9127-9
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- Publication type:
- Article
A Nanostructured Matrices Assessment to Study Drug Distribution in Solid Tumor Tissues by Mass Spectrometry Imaging.
- Published in:
- Nanomaterials (2079-4991), 2017, v. 7, n. 3, p. 71, doi. 10.3390/nano7030071
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- Publication type:
- Article
Wiring miRNAs to pathways: a topological approach to integrate miRNA and mRNA expression profiles.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 11, p. e96, doi. 10.1093/nar/gku354
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- Publication type:
- Article
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. 16, p. 5353, doi. 10.1093/nar/gkp582
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- Publication type:
- Article
Hematopoietic toxicity and cell cycle perturbations induced by new DNA minor groove-alkylating agents.
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- International Journal of Cancer, 1997, v. 72, n. 5, p. 801, doi. 10.1002/(SICI)1097-0215(19970904)72:5<801::AID-IJC16>3.0.CO;2-B
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- Publication type:
- Article
Sensitivity of CHO mutant cell lines with specific defects in nucleotide excision repair to different anti-cancer agents.
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- International Journal of Cancer, 1996, v. 66, n. 6, p. 779, doi. 10.1002/(SICI)1097-0215(19960611)66:6<779::AID-IJC12>3.0.CO;2-Z
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- Publication type:
- Article
In vivo anti-tumor activity of synthetic ether lipids is not enhanced by pharmacological modulation of tumor lipid composition.
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- International Journal of Cancer, 1994, v. 59, n. 4, p. 580, doi. 10.1002/ijc.2910590423
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- Publication type:
- Article
Intracellular glutathione heterogeneity in L1210 murine leukemia sublines made resistant to dna-interacting anti-neoplastic agents.
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- International Journal of Cancer, 1993, v. 54, n. 3, p. 435, doi. 10.1002/ijc.2910540314
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- Publication type:
- Article
Establishment of l1210 leukemia cells resistant to the distamycin-a derivative (FCE 24517): Characterization and cross-resistance studies.
- Published in:
- International Journal of Cancer, 1993, v. 53, n. 2, p. 308, doi. 10.1002/ijc.2910530223
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- Publication type:
- Article
Increase in topoisomerase-II-mediated dna breaks and cytotoxicity of VP16 in human U937 lymphoma cells pretreated with low doses of methotrexate.
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- International Journal of Cancer, 1990, v. 45, n. 1, p. 156, doi. 10.1002/ijc.2910450128
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- Publication type:
- Article
Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy.
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- International Journal of Cancer, 1989, v. 44, n. 3, p. 494, doi. 10.1002/ijc.2910440320
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- Publication type:
- Article
High Penetration of Paclitaxel in Abdominal Wall of Rabbits after Hyperthermic Intraperitoneal Administration of Nab-Paclitaxel Compared to Standard Paclitaxel Formulation.
- Published in:
- Pharmaceutical Research, 2017, v. 34, n. 6, p. 1180, doi. 10.1007/s11095-017-2132-4
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- Publication type:
- Article
Transfer of a Human Chromosomal Vector from a Hamster Cell Line to a Mouse Embryonic Stem Cell Line.
- Published in:
- Stem Cells, 2007, v. 25, n. 10, p. 2543, doi. 10.1634/stemcells.2007-0052
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- Publication type:
- Article
Structural characterization of mono- and dihydroxylated metabolites of paclitaxel in rat bile using liquid chromatography/ion spray tandem mass spectrometry.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 1997, v. 11, n. 9, p. 1025, doi. 10.1002/(SICI)1097-0231(19970615)11:9<1025::AID-RCM956>3.0.CO;2-M
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- Publication type:
- Article
Trabectedin is a novel chemotherapy agent for diffuse large B cell lymphoma.
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- British Journal of Haematology, 2019, v. 184, n. 6, p. 1022, doi. 10.1111/bjh.15212
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- Publication type:
- Article
Histologic subtyping affecting outcome of triple negative breast cancer: a large Sardinian population-based analysis.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Self‐Assembling PCL‐Based Nanoparticles as PTX Solubility Enhancer Excipients.
- Published in:
- Macromolecular Bioscience, 2018, v. 18, n. 10, p. N.PAG, doi. 10.1002/mabi.201800164
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- Publication type:
- Article
Trabectedin in Malignant Pleural Mesothelioma: Results From the Multicentre, Single Arm, Phase II ATREUS Study.
- Published in:
- Clinical Lung Cancer, 2021, v. 22, n. 4, p. 361, doi. 10.1016/j.cllc.2020.06.028
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- Publication type:
- Article
Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging.
- Published in:
- Scientific Reports, 2016, p. 39284, doi. 10.1038/srep39284
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- Publication type:
- Article
Determination of Paclitaxel Distribution in Solid Tumors by Nano-Particle Assisted Laser Desorption Ionization Mass Spectrometry Imaging.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072532
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- Publication type:
- Article
Prevention of Disuse Muscle Atrophy by Dietary Ingestion of 8-Prenylnaringenin in Denervated Mice.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045048
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- Publication type:
- Article
Early Sorafenib-Induced Toxicity Is Associated with Drug Exposure and UGTIA9 Genetic Polymorphism in Patients with Solid Tumors: A Preliminary Study.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042875
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- Publication type:
- Article
A Systems Biology Approach to Characterize the Regulatory Networks Leading to Trabectedin Resistance in an In Vitro Model of Myxoid Liposarcoma.
- Published in:
- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035423
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- Publication type:
- Article
Reduced Expression of the ROCK Inhibitor Rnd3 Is Associated with Increased Invasiveness and Metastatic Potential in Mesenchymal Tumor Cells.
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- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014154
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- Publication type:
- Article
Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of the novel inhibitor of angiogenesis E-3810 in human plasma and its application in a clinical pharmacokinetic study.
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- Journal of Mass Spectrometry, 2011, v. 46, n. 10, p. 1039, doi. 10.1002/jms.1985
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- Publication type:
- Article
Simultaneous determination of gemcitabine and its main metabolite, dFdU, in plasma of patients with advanced non-small-cell lung cancer by high-performance liquid chromatography-tandem mass spectrometry.
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- Journal of Mass Spectrometry, 2008, v. 43, n. 2, p. 216, doi. 10.1002/jms.1293
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- Publication type:
- Article
Effects of a novel DNA-damaging agent on the budding yeast Saccharomyces cerevisiae cell cycle.
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- Yeast, 1996, v. 12, n. 4, p. 349, doi. 10.1002/(SICI)1097-0061(19960330)12:4<349::AID-YEA917>3.0.CO;2-O
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- Publication type:
- Article
Disruptions in antigen processing and presentation machinery on sarcoma.
- Published in:
- Cancer Immunology, Immunotherapy, 2024, v. 73, n. 11, p. 1, doi. 10.1007/s00262-024-03822-2
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- Publication type:
- Article
Targeted Mutational Analysis of Circulating Tumor DNA to Decipher Temporal Heterogeneity of High-Grade Serous Ovarian Cancer.
- Published in:
- Cancers, 2022, v. 14, n. 15, p. 3697, doi. 10.3390/cancers14153697
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- Publication type:
- Article
Comprehensive Profiling of Hypoxia-Related miRNAs Identifies miR-23a-3p Overexpression as a Marker of Platinum Resistance and Poor Prognosis in High-Grade Serous Ovarian Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 13, p. 3358, doi. 10.3390/cancers13133358
- By:
- Publication type:
- Article
Liquid Biopsy in the Clinical Management of High-Grade Serous Epithelial Ovarian Cancer—Current Use and Future Opportunities.
- Published in:
- Cancers, 2021, v. 13, n. 10, p. 2386, doi. 10.3390/cancers13102386
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- Publication type:
- Article
Intersection of DNA Repair Pathways and the Immune Landscape Identifies PD-L2 as a Prognostic Marker in Epithelial Ovarian Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 8, p. 1972, doi. 10.3390/cancers13081972
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- Publication type:
- Article
Treatment of Angiosarcoma with Pazopanib and Paclitaxel: Results of the EVA (Evaluation of Votrient ® in Angiosarcoma) Phase II Trial of the German Interdisciplinary Sarcoma Group (GISG-06).
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- Cancers, 2021, v. 13, n. 6, p. 1223, doi. 10.3390/cancers13061223
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- Publication type:
- Article
Trabectedin and Lurbinectedin Extend Survival of Mice Bearing C26 Colon Adenocarcinoma, without Affecting Tumor Growth or Cachexia.
- Published in:
- Cancers, 2020, v. 12, n. 8, p. 2312, doi. 10.3390/cancers12082312
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- Publication type:
- Article
Optimization of a Luciferase-Expressing Non-Invasive Intrapleural Model of Malignant Mesothelioma in Immunocompetent Mice.
- Published in:
- Cancers, 2020, v. 12, n. 8, p. 2136, doi. 10.3390/cancers12082136
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- Publication type:
- Article
Interferon-β can induce progesterone receptors in human endometrial adenocarcinoma.
- Published in:
- Cancer (0008543X), 1996, v. 78, n. 3, p. 448, doi. 10.1002/(SICI)1097-0142(19960801)78:3<448::AID-CNCR11>3.0.CO;2-Z
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- Publication type:
- Article
Trabectedin and Plitidepsin: Drugs from the Sea that Strike the Tumor Microenvironment.
- Published in:
- Marine Drugs, 2014, v. 12, n. 2, p. 719, doi. 10.3390/md12020719
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- Publication type:
- Article
Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 4, p. 1319, doi. 10.1007/s10637-011-9689-2
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- Publication type:
- Article
Tumor Immune Microenvironment and Genetic Alterations in Mesothelioma.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.660039
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- Publication type:
- Article
Important functional role of the protein osteopontin in the progression of malignant pleural mesothelioma.
- Published in:
- Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1116430
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- Publication type:
- Article