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Heterologous expression of influenza haemagglutinin leads to early and transient activation of the unfolded protein response in Nicotiana benthamiana.
Published in:
Plant Biotechnology Journal, 2024, v. 22, n. 5, p. 1146, doi. 10.1111/pbi.14252
By:
- Hamel, Louis‐Philippe;
- Comeau, Marc‐André;
- Tardif, Rachel;
- Poirier‐Gravel, Francis;
- Paré, Marie‐Ève;
- Lavoie, Pierre‐Olivier;
- Goulet, Marie‐Claire;
- Michaud, Dominique;
- D'Aoust, Marc‐André
Publication type:
Article
Molecular responses of agroinfiltrated Nicotiana benthamiana leaves expressing suppressor of silencing P19 and influenza virus‐like particles.
Published in:
Plant Biotechnology Journal, 2024, v. 22, n. 5, p. 1078, doi. 10.1111/pbi.14247
By:
- Hamel, Louis‐Philippe;
- Tardif, Rachel;
- Poirier‐Gravel, Francis;
- Rasoolizadeh, Asieh;
- Brosseau, Chantal;
- Giroux, Geneviève;
- Lucier, Jean‐François;
- Goulet, Marie‐Claire;
- Barrada, Adam;
- Paré, Marie‐Ève;
- Roussel, Élise;
- Comeau, Marc‐André;
- Lavoie, Pierre‐Olivier;
- Moffett, Peter;
- Michaud, Dominique;
- D'Aoust, Marc‐André
Publication type:
Article
In planta expression of active bacterial GDP‐6‐deoxy‐d‐lyxo‐4‐hexulose reductase for glycan modulation.
Published in:
Plant Biotechnology Journal, 2023, v. 21, n. 10, p. 1929, doi. 10.1111/pbi.14131
By:
- Kogelmann, Benjamin;
- Palt, Roman;
- Maresch, Daniel;
- Strasser, Richard;
- Altmann, Friedrich;
- Kallolimath, Somanath;
- Sun, Lin;
- D'Aoust, Marc‐André;
- Lavoie, Pierre‐Olivier;
- Saxena, Pooja;
- Gach, Johannes S.;
- Steinkellner, Herta
Publication type:
Article
Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH‐dependent.
Published in:
Plant Biotechnology Journal, 2018, v. 16, n. 11, p. 1928, doi. 10.1111/pbi.12928
By:
- Jutras, Philippe V.;
- Goulet, Marie‐Claire;
- Lavoie, Pierre‐Olivier;
- D'Aoust, Marc‐André;
- Sainsbury, Frank;
- Michaud, Dominique
Publication type:
Article
Cell wall biochemical alterations during Agrobacterium-mediated expression of haemagglutinin-based influenza virus-like vaccine particles in tobacco.
Published in:
Plant Biotechnology Journal, 2017, v. 15, n. 3, p. 285, doi. 10.1111/pbi.12607
By:
- Le Mauff, François;
- Loutelier‐Bourhis, Corinne;
- Bardor, Muriel;
- Berard, Caroline;
- Doucet, Alain;
- D'Aoust, Marc‐André;
- Vezina, Louis‐Philippe;
- Driouich, Azeddine;
- Couture, Manon M.‐J.;
- Lerouge, Patrice
Publication type:
Article
Multiplexed, targeted gene editing in Nicotiana benthamiana for glyco-engineering and monoclonal antibody production.
Published in:
Plant Biotechnology Journal, 2016, v. 14, n. 2, p. 533, doi. 10.1111/pbi.12403
By:
- Li, Jin;
- Stoddard, Thomas J.;
- Demorest, Zachary L.;
- Lavoie, Pierre‐Olivier;
- Luo, Song;
- Clasen, Benjamin M.;
- Cedrone, Frederic;
- Ray, Erin E.;
- Coffman, Andrew P.;
- Daulhac, Aurelie;
- Yabandith, Ann;
- Retterath, Adam J.;
- Mathis, Luc;
- Voytas, Daniel F.;
- D'Aoust, Marc‐André;
- Zhang, Feng
Publication type:
Article
Leaf proteome rebalancing in Nicotiana benthamiana for upstream enrichment of a transiently expressed recombinant protein.
Published in:
Plant Biotechnology Journal, 2015, v. 13, n. 8, p. 1169, doi. 10.1111/pbi.12452
By:
- Robert, Stéphanie;
- Goulet, Marie‐Claire;
- D'Aoust, Marc‐André;
- Sainsbury, Frank;
- Michaud, Dominique
Publication type:
Article
Tomato cystatin Sl CYS8 as a stabilizing fusion partner for human serpin expression in plants.
Published in:
Plant Biotechnology Journal, 2013, v. 11, n. 9, p. 1058, doi. 10.1111/pbi.12098
By:
- Sainsbury, Frank;
- Varennes‐Jutras, Philippe;
- Goulet, Marie‐Claire;
- D'Aoust, Marc‐André;
- Michaud, Dominique
Publication type:
Article
A protease activity-depleted environment for heterologous proteins migrating towards the leaf cell apoplast.
Published in:
Plant Biotechnology Journal, 2012, v. 10, n. 1, p. 83, doi. 10.1111/j.1467-7652.2011.00643.x
By:
- Goulet, Charles;
- Khalf, Moustafa;
- Sainsbury, Frank;
- D'Aoust, Marc‐André;
- Michaud, Dominique
Publication type:
Article
The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza.
Published in:
Plant Biotechnology Journal, 2010, v. 8, n. 5, p. 607, doi. 10.1111/j.1467-7652.2009.00496.x
By:
- D'Aoust, Marc-André;
- Couture, Manon M.-J.;
- Charland, Nathalie;
- Trépanier, Sonia;
- Landry, Nathalie;
- Ors, Frédéric;
- Vézina, Louis-P.
Publication type:
Article
Transient co-expression for fast and high-yield production of antibodies with human-like N-glycans in plants.
Published in:
Plant Biotechnology Journal, 2009, v. 7, n. 5, p. 442, doi. 10.1111/j.1467-7652.2009.00414.x
By:
- Vézina, Louis‐P.;
- Faye, Loïc;
- Lerouge, Patrice;
- D'Aoust, Marc‐André;
- Marquet‐Blouin, Estelle;
- Burel, Carole;
- Lavoie, Pierre‐Olivier;
- Bardor, Muriel;
- Gomord, Véronique
Publication type:
Article
Influenza virus-like particles produced by transient expression in Nicotiana benthamiana induce a protective immune response against a lethal viral challenge in mice.
Published in:
Plant Biotechnology Journal, 2008, v. 6, n. 9, p. 930, doi. 10.1111/j.1467-7652.2008.00384.x
By:
- D'Aoust, Marc‐André;
- Lavoie, Pierre‐Olivier;
- Couture, Manon M.‐J.;
- Trépanier, Sonia;
- Guay, Jean‐Martin;
- Dargis, Michèle;
- Mongrand, Sébastien;
- Landry, Nathalie;
- Ward, Brian J.;
- Vézina, Louis‐P.
Publication type:
Article
Down-regulated expression of plant-specific glycoepitopes in alfalfa.
Published in:
Plant Biotechnology Journal, 2008, v. 6, n. 7, p. 702, doi. 10.1111/j.1467-7652.2008.00353.x
By:
- Sourrouille, Christophe;
- Marquet‐Blouin, Estelle;
- D'Aoust, Marc‐André;
- Kiefer‐Meyer, Marie‐Christine;
- Seveno, Martial;
- Pagny‐Salehabadi, Sophie;
- Bardor, Muriel;
- Durambur, Gaelle;
- Lerouge, Patrice;
- Vezina, Louis;
- Gomord, Véronique
Publication type:
Article
Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34728-1
By:
- Gobeil, Philipe;
- Pillet, Stéphane;
- Boulay, Iohann;
- Charland, Nathalie;
- Lorin, Aurélien;
- Cheng, Matthew P.;
- Vinh, Donald C.;
- Boutet, Philippe;
- Van Der Most, Robbert;
- Roman, François;
- Ceregido, Maria Angeles;
- Landry, Nathalie;
- D'Aoust, Marc-André;
- Ward, Brian J.
Publication type:
Article
Production of Biopharmaceuticals in Nicotiana benthamiana —Axillary Stem Growth as a Key Determinant of Total Protein Yield.
Published in:
Frontiers in Plant Science, 2019, p. N.PAG, doi. 10.3389/fpls.2019.00735
By:
- Goulet, Marie-Claire;
- Gaudreau, Linda;
- Gagné, Marielle;
- Maltais, Anne-Marie;
- Laliberté, Ann-Catherine;
- Éthier, Gilbert;
- Bechtold, Nicole;
- Martel, Michèle;
- D'Aoust, Marc-André;
- Gosselin, André;
- Pepin, Steeve;
- Michaud, Dominique
Publication type:
Article
Plant molecular farming in the wake of the closure of Medicago Inc.
Published in:
2023
By:
- Benvenuto, Eugenio;
- Broer, Inge;
- D'Aoust, Marc-André;
- Hitzeroth, Inga;
- Hundleby, Penny;
- Menassa, Rima;
- Oksman-Caldentey, Kirsi-Marja;
- Peyret, Hadrien;
- Salgueiro, Sancha;
- Saxena, Pooja;
- Stander, Jennifer;
- Warzecha, Heribert;
- Ma, Julian
Publication type:
Letter
Protection of Recombinant Mammalian Antibodies from Development-Dependent Proteolysis in Leaves of <i>Nicotiana benthamiana</i>.
Published in:
PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0070203
By:
- Robert, Stéphanie;
- Khalf, Moustafa;
- Goulet, Marie-Claire;
- D’Aoust, Marc-André;
- Sainsbury, Frank;
- Michaud, Dominique
Publication type:
Article
Generation and characterization of a trackable plant-made influenza H5 virus-like particle (VLP) containing enhanced green fluorescent protein (eGFP).
Published in:
FASEB Journal, 2015, v. 29, n. 9, p. 3817, doi. 10.1096/fj.15-270421
By:
- Young, Katie R.;
- Arthus-Cartier, Guillaume;
- Yam, Karen K.;
- Lavoie, Pierre-Olivier;
- Landry, Nathalie;
- D'Aoust, Marc-André;
- Vézina, Louis-Philippe;
- Couture, Manon M.-J.;
- Ward, Brian J.
Publication type:
Article
An oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1.
Published in:
Frontiers in Plant Science, 2023, p. 1, doi. 10.3389/fpls.2023.1233666
By:
- Beihammer, Gernot;
- König-Beihammer, Julia;
- Kogelmann, Benjamin;
- Ruocco, Valentina;
- Grünwald-Gruber, Clemens;
- D’Aoust, Marc-André;
- Lavoie, Pierre-Olivier;
- Saxena, Pooja;
- Gach, Johannes S.;
- Steinkellner, Herta;
- Strasser, Richard
Publication type:
Article
Elimination of receptor binding by influenza hemagglutinin improves vaccine-induced immunity.
Published in:
NPJ Vaccines, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41541-022-00463-3
By:
- Hendin, Hilary E.;
- Lavoie, Pierre-Olivier;
- Gravett, Jason M.;
- Pillet, Stéphane;
- Saxena, Pooja;
- Landry, Nathalie;
- D'Aoust, Marc-André;
- Ward, Brian J.
Publication type:
Article
A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice.
Published in:
Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102516
By:
- Fausther-Bovendo, Hugues;
- Hamelin, Marie-Eve;
- Carbonneau, Julie;
- Venable, Marie-Christine;
- Checkmahomed, Liva;
- Lavoie, Pierre-Olivier;
- Ouellet, Marie-Ève;
- Boivin, Guy;
- D'Aoust, Marc-André;
- Kobinger, Gary P.
Publication type:
Article
A genome‐edited N. benthamiana line for industrial‐scale production of recombinant glycoproteins with targeted N‐glycosylation.
Published in:
Biotechnology Journal, 2024, v. 19, n. 1, p. 1, doi. 10.1002/biot.202300323
By:
- Kogelmann, Benjamin;
- Melnik, Stanislav;
- Bogner, Michaela;
- Kallolimath, Somanath;
- Stöger, Eva;
- Sun, Lin;
- Strasser, Richard;
- D'Aoust, Marc‐André;
- Lavoie, Pierre‐Olivier;
- Saxena, Pooja;
- Gach, Johannes S.;
- Steinkellner, Herta
Publication type:
Article
Modulating secretory pathway pH by proton channel co-expression can increase recombinant protein stability in plants.
Published in:
Biotechnology Journal, 2015, v. 10, n. 9, p. 1478, doi. 10.1002/biot.201500056
By:
- Jutras, Philippe V.;
- D'Aoust, Marc‐André;
- Couture, Manon M.‐J.;
- Vézina, Louis‐Philippe;
- Goulet, Marie‐Claire;
- Michaud, Dominique;
- Sainsbury, Frank
Publication type:
Article
Expression of multiple proteins using full-length and deleted versions of cowpea mosaic virus RNA-2.
Published in:
Plant Biotechnology Journal, 2008, v. 6, n. 1, p. 82, doi. 10.1111/j.1467-7652.2007.00303.x
By:
- Sainsbury, Frank;
- Lavoie, Pierre‐Olivier;
- D'Aoust, Marc‐André;
- Vézina, Louis‐Philippe;
- Lomonossoff, George P.
Publication type:
Article
Engineering of a sialic acid synthesis pathway in transgenic plants by expression of bacterial Neu5Ac-synthesizing enzymes.
Published in:
Plant Biotechnology Journal, 2007, v. 5, n. 1, p. 16, doi. 10.1111/j.1467-7652.2006.00211.x
By:
- Paccalet, Thomas;
- Bardor, Muriel;
- Rihouey, Christophe;
- Delmas, Frédéric;
- Chevalier, Christian;
- D'Aoust, Marc‐André;
- Faye, Loïc;
- Vézina, Louis;
- Gomord, Véronique;
- Lerouge, Patrice
Publication type:
Article

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