Works by Cypess, Aaron M.

Results: 39

Variable Cold-Induced Brown Adipose Tissue Response to Thyroid Hormone Status.

Published in:

Thyroid, 2017, v. 27, n. 1, p. 1, doi. 10.1089/thy.2015.0646

By:

Gavrila, Alina;
Hasselgren, Per-Olof;
Glasgow, Allison;
Doyle, Ashley N.;
Lee, Alice J.;
Fox, Peter;
Gautam, Shiva;
Hennessey, James V.;
Kolodny, Gerald M.;
Cypess, Aaron M.

Publication type:

Article

Measurement of Skin-to-Kidney Distance in Children: Implications for Quantitative Renography.

Published in:

Journal of Nuclear Medicine, 1990, v. 31, n. 3, p. 287

By:

Maneval, Daniel C.;
Magill, H. Lynn;
Cypess, Aaron M.;
Rodman, John H.

Publication type:

Article

Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin.

Published in:

Nature Cell Biology, 2005, v. 7, n. 6, p. 601, doi. 10.1038/ncb1259

By:

Tseng, Yu-Hua;
Butte, Atul J.;
Kokkotou, Efi;
Yechoor, Vijay K.;
Taniguchi, Cullen M.;
Kriauciunas, Kristina M.;
Cypess, Aaron M.;
Niinobe, Michio;
Yoshikawa, Kazuaki;
Patti, Mary Elizabeth;
Kahn, C. Ronald

Publication type:

Article

Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat.

Published in:

Nature, 2013, v. 495, n. 7441, p. 379, doi. 10.1038/nature11943

By:

Schulz, Tim J.;
Huang, Ping;
Huang, Tian Lian;
Xue, Ruidan;
McDougall, Lindsay E.;
Townsend, Kristy L.;
Cypess, Aaron M.;
Mishina, Yuji;
Gussoni, Emanuela;
Tseng, Yu-Hua

Publication type:

Article

Micro RNA-455 regulates brown adipogenesis via a novel HIF1an- AMPK- PGC1α signaling network.

Published in:

EMBO Reports, 2015, v. 16, n. 10, p. 1378, doi. 10.15252/embr.201540837

By:

Zhang, Hongbin;
Guan, Meiping;
Townsend, Kristy L;
Huang, Tian Lian;
An, Ding;
Yan, Xu;
Xue, Ruidan;
Schulz, Tim J;
Winnay, Jonathon;
Mori, Marcelo;
Hirshman, Michael F;
Kristiansen, Karsten;
Tsang, John S;
White, Andrew P;
Cypess, Aaron M;
Goodyear, Laurie J;
Tseng, Yu‐Hua

Publication type:

Article

Correction: Effect of Chronic Athletic Activity on Brown Fat in Young Women.

Published in:

2016

By:

Singhal, Vibha;
Maffazioli, Giovana D.;
Ackerman, Kathryn E.;
Lee, Hang;
Elia, Elisa F.;
Woolley, Ryan;
Kolodny, Gerald;
Cypess, Aaron M.;
Misra, Madhusmita

Publication type:

Correction Notice

Effect of Chronic Athletic Activity on Brown Fat in Young Women.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0156353

By:

Singhal, Vibha;
Maffazioli, Giovana D.;
Ackerman, Kate E.;
Lee, Hang;
Elia, Elisa F.;
Woolley, Ryan;
Kolodny, Gerald;
Cypess, Aaron M.;
Misra, Madhusmita

Publication type:

Article

The prevalence and predictors of active brown adipose tissue in Chinese adults.

Published in:

European Journal of Endocrinology, 2014, v. 170, n. 3, p. 359, doi. 10.1530/EJE-13-0712

By:

Zhaoyun Zhang;
Cypess, Aaron M.;
Qing Miao;
Hongying Ye;
Chong Wee Liew;
Qiongyue Zhang;
Ruidan Xue;
Shuo Zhang;
Chuantao Zuo;
Zhensheng Xu;
Qiqun Tang;
Renming Hu;
Yihui Guan;
Yiming Li

Publication type:

Article

Brown Adipose Tissue Activation in Humans Increases Plasma Levels of Lipid Mediators.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 7, p. 1837, doi. 10.1210/clinem/dgae016

By:

Walker, Mary E;
Kodani, Sean D;
Mena, Hebe Agustina;
Tseng, Yu-Hua;
Cypess, Aaron M;
Spite, Matthew

Publication type:

Article

PET Imaging of Human Brown Adipose Tissue with the TSPO Tracer [11C]PBR28.

Published in:

2018

By:

Ran, Chongzhao;
Albrecht, Daniel S.;
Bredella, Miriam A.;
Yang, Jing;
Yang, Jian;
Liang, Steven H.;
Cypess, Aaron M.;
Loggia, Marco L.;
Atassi, Nazem;
Moore, Anna

Publication type:

journal article

Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes.

Published in:

Nature Medicine, 2015, v. 21, n. 7, p. 760, doi. 10.1038/nm.3881

By:

Xue, Ruidan;
Lynes, Matthew D;
Dreyfuss, Jonathan M;
Shamsi, Farnaz;
Schulz, Tim J;
Zhang, Hongbin;
Huang, Tian Lian;
Townsend, Kristy L;
Li, Yiming;
Takahashi, Hirokazu;
Weiner, Lauren S;
White, Andrew P;
Lynes, Maureen S;
Rubin, Lee L;
Goodyear, Laurie J;
Cypess, Aaron M;
Tseng, Yu-Hua

Publication type:

Article

Genetic and functional characterization of clonally derived adult human brown adipocytes.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 389, doi. 10.1038/nm.3819

By:

Shinoda, Kosaku;
Luijten, Ineke H N;
Hasegawa, Yutaka;
Hong, Haemin;
Sonne, Si B;
Kim, Miae;
Xue, Ruidan;
Chondronikola, Maria;
Cypess, Aaron M;
Tseng, Yu-Hua;
Nedergaard, Jan;
Sidossis, Labros S;
Kajimura, Shingo

Publication type:

Article

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.

Published in:

Nature Medicine, 2013, v. 19, n. 5, p. 635, doi. 10.1038/nm.3112

By:

Cypess, Aaron M;
White, Andrew P;
Vernochet, Cecile;
Schulz, Tim J;
Xue, Ruidan;
Sass, Christina A;
Huang, Tian Liang;
Roberts-Toler, Carla;
Weiner, Lauren S;
Sze, Cathy;
Chacko, Aron T;
Deschamps, Laura N;
Herder, Lindsay M;
Truchan, Nathan;
Glasgow, Allison L;
Holman, Ashley R;
Gavrila, Alina;
Hasselgren, Per-Olof;
Mori, Marcelo A;
Molla, Michael

Publication type:

Article

Pheochromocytoma and Paraganglioma Patients With Poor Survival Often Show Brown Adipose Tissue Activation.

Published in:

2020

By:

Abdul Sater, Zahraa;
Jha, Abhishek;
Hamimi, Ahmed;
Mandl, Adel;
Hartley, Iris R;
Gubbi, Sriram;
Patel, Mayank;
Gonzales, Melissa;
Taïeb, David;
Civelek, Ali Cahid;
Gharib, Ahmed M;
Auh, Sungyoung;
O'Mara, Alana E;
Pacak, Karel;
Cypess, Aaron M

Publication type:

journal article

Thyroid Hormone Effects on Glucose Disposal in Patients With Insulin Receptor Mutations.

Published in:

2019

By:

Kushchayeva, Yevgeniya S;
Startzell, Megan;
Cochran, Elaine;
Auh, Sungyoung;
Sekizkardes, Hilal;
Soldin, Steven J;
Kushchayev, Sergiy V;
Dieckmann, William;
Skarulis, Monica;
Abdul Sater, Zahraa;
Brychta, Robert J;
Cypess, Aaron M;
Lin, Tzu-Chun;
Lightbourne, Marissa;
Millo, Corina;
Brown, Rebecca J

Publication type:

journal article

Quantification of the Capacity for Cold-Induced Thermogenesis in Young Men With and Without Obesity.

Published in:

2019

By:

Brychta, Robert J;
Huang, Shan;
Wang, Juan;
Leitner, Brooks P;
Hattenbach, Jacob D;
Bell, Sarah L;
Fletcher, Laura A;
Perron Wood, Rachel;
Idelson, Christopher R;
Duckworth, Courtney J;
McGehee, Suzanne;
Courville, Amber B;
Bernstein, Shanna B;
Reitman, Marc L;
Cypess, Aaron M;
Chen, Kong Y

Publication type:

journal article

1177-P: The Reduction in Hepatic Steatosis after Cushing's Syndrome Treatment Is a Marker of Improving Glycemia.

Published in:

Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1177-P

By:

PIERCE, ANNE;
SATER, ZAHRAA A.;
CYPESS, AARON M.

Publication type:

Article

1701-P: The Role of UGT1a in Regulating Brown Adipose Tissue and Thermogenic Function.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1701-P

By:

KODANI, SEAN;
LYNES, MATTHEW;
SHAMSI, FARNAZ;
WANG, CHIH-HAO;
SUGIMOTO, SATORU;
XUE, RUIDAN;
HUANG, TIAN LIAN;
WHITE, ANDREW P.;
CYPESS, AARON M.;
TSENG, YU-HUA

Publication type:

Article

1680-P: A Novel Immunomodulatory Combination That Decreases Adipose Tissue and Systemic Inflammation and Improves Metabolism in Dio Mice.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1680-P

By:

SATER, ZAHRAA A.;
CERO, CHERYL;
LEA, HANNAH J.;
ZHU, KENNETH Y.;
GAVRILOVA, OKSANA;
CYPESS, AARON M.

Publication type:

Article

232-LB: Chronic Adrenergic Stimulation of Human Brown and White Adipose Tissue Increases Bile Acid Synthesis Enzyme Expression and Plasma Bile Acid Levels.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-232-LB

By:

ZHU, KENNETH Y.;
LEA, HANNAH J.;
CERO, CHERYL;
CYPESS, AARON M.

Publication type:

Article

208-LB: Stimulation of the ß3 Adrenergic Receptors Prime Human White and Brown Adipocytes for Increased Lipolysis and Thermogenesis.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-208-LB

By:

LEA, HANNAH J.;
ZHU, KENNETH Y.;
CERO, CHERYL;
CYPESS, AARON M.

Publication type:

Article

2020-P: ß3-Adrenergic Receptors Regulate Lipolysis and Thermogenesis in Human Brown/Beige Adipocytes.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2020-P

By:

CERO, CHERYL;
LEA, HANNAH J.;
ZHU, KENNETH Y.;
CYPESS, AARON M.

Publication type:

Article

137-OR: The Selective Human Beta 3 Adrenergic Receptor Mirabegron Potently Activates Lipolysis in Human White Adipocytes.

Published in:

Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-137-OR

By:

CERO, CHERYL;
JOHNSON, JAMES W.;
O'MARA, ALANA;
LINDERMAN, JOYCE D.;
CYPESS, AARON M.

Publication type:

Article

Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist.

Published in:

2018

By:

Baskin, Alison S.;
Linderman, Joyce D.;
Brychta, Robert J.;
McGehee, Suzanne;
Anflick-Chames, Esti;
Cero, Cheryl;
Johnson, James W.;
O'Mara, Alana E.;
Fletcher, Laura A.;
Leitner, Brooks P.;
Duckworth, Courtney J.;
Shan Huang;
Kong Y. Chen;
Cypess, Aaron M.;
Hongyi Cai;
Garraffo, H. Martin;
Walter, Peter J.;
Millo, Corina M.;
Dieckmann, William;
Herscovitch, Peter

Publication type:

journal article

Cellular bioenergetics as a target for obesity therapy.

Published in:

2010

By:

Yu-Hua Tseng;
Cypess, Aaron M.;
Kahn, C. Ronald;
Tseng, Yu-Hua

Publication type:

journal article

Combining a β3 adrenergic receptor agonist with alpha‐lipoic acid reduces inflammation in male mice with diet‐induced obesity.

Published in:

Obesity (19307381), 2022, v. 30, n. 1, p. 153, doi. 10.1002/oby.23309

By:

Abdul Sater, Zahraa;
Cero, Cheryl;
Pierce, Anne E.;
Lea, Hannah J.;
Abdul Sater, Houssein;
Zhu, Kenneth Y.;
Liu, Naili;
Ma, Yinyan;
Gavrilova, Oksana;
Cypess, Aaron M.

Publication type:

Article

Sexual Dimorphisms in Adult Human Brown Adipose Tissue.

Published in:

2020

By:

Fletcher, Laura A.;
Kim, Katherine;
Leitner, Brooks P.;
Cassimatis, Thomas M.;
O'Mara, Alana E.;
Johnson, James W.;
Halprin, Molly S.;
McGehee, Suzanne M.;
Brychta, Robert J.;
Cypess, Aaron M.;
Chen, Kong Y.

Publication type:

journal article

Diet-induced obesity causes insulin resistance in mouse brown adipose tissue.

Published in:

Obesity (19307381), 2015, v. 23, n. 9, p. 1765, doi. 10.1002/oby.21134

By:

Roberts‐Toler, Carla;
O'Neill, Brian T.;
Cypess, Aaron M.

Publication type:

Article

Anatomical and Functional Assessment of Brown Adipose Tissue by Magnetic Resonance Imaging.

Published in:

Obesity (19307381), 2012, v. 20, n. 7, p. 1519, doi. 10.1038/oby.2012.22

By:

Chen, Y. Iris;
Cypess, Aaron M.;
Sass, Christina A.;
Brownell, Anna-Liisa;
Jokivarsi, Kimmo T.;
Kahn, C. Ronald;
Kwong, Kenneth K.

Publication type:

Article

Quantification of Human and Rodent Brown Adipose Tissue Function Using 99mTc-Methoxyisobutylisonitrile SPECT/CT and 99mF-FDG PET/CT.

Published in:

Journal of Nuclear Medicine, 2013, v. 54, n. 11, p. 1896, doi. 10.2967/jnumed.113.121012

By:

Cypess, Aaron M.;
Doyle, Ashley N.;
Sass, Christina A.;
Tian Lian Huang;
Mowschenson, Peter M.;
Rosen, Harold N.;
Yu-Hua Tseng;
Palmer III, Edwin L.;
Kolodny, Gerald M.

Publication type:

Article

Measurement of Human Brown Adipose Tissue Volume and Activity Using Anatomic MR Imaging and Functional MR Imaging.

Published in:

Journal of Nuclear Medicine, 2013, v. 54, n. 9, p. 1584, doi. 10.2967/jnumed.112.117275

By:

Yin-Ching Iris Chen;
Cypess, Aaron M.;
Yih-Chieh Chen;
Palmer, Matthew;
Kolodny, Gerald;
Kahn, C. Ronald;
Kwong, Kenneth K.

Publication type:

Article

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.

Published in:

Science Translational Medicine, 2014, v. 6, n. 247, p. 1, doi. 10.1126/scitranslmed.3008490

By:

Ussar, Siegfried;
Lee, Kevin Y.;
Dankel, Simon N.;
Boucher, Jeremie;
Haering, Max-Felix;
Kleinridders, Andre;
Thomou, Thomas;
Xue, Ruidan;
Macotela, Yazmin;
Cypess, Aaron M.;
Yu-Hua Tseng;
Mellgren, Gunnar;
Kahn, C. Ronald

Publication type:

Article

Standardized In Vitro Models of Human Adipose Tissue Reveal Metabolic Flexibility in Brown Adipocyte Thermogenesis.

Published in:

Endocrinology, 2023, v. 164, n. 12, p. 1, doi. 10.1210/endocr/bqad161

By:

Cero, Cheryl;
Shu, Weiguo;
Reese, Amy L;
Douglas, Diana;
Maddox, Michael;
Singh, Ajeet P;
Ali, Sahara L;
Zhu, Alexander R;
Katz, Jacqueline M;
Pierce, Anne E;
Long, Kelly T;
Nilubol, Naris;
Cypess, Raymond H;
Jacobs, Jonathan L;
Tian, Fang;
Cypess, Aaron M

Publication type:

Article

Effects of lifestyle modification and metformin on irisin and FGF21 among HIV-infected subjects with the metabolic syndrome.

Published in:

Clinical Endocrinology, 2015, v. 82, n. 5, p. 678, doi. 10.1111/cen.12582

By:

Srinivasa, Suman;
Wong, Kimberly;
Fitch, Kathleen V.;
Wei, Jeffrey;
Petrow, Eva;
Cypess, Aaron M.;
Torriani, Martin;
Grinspoon, Steven K.

Publication type:

Article

Dysfunctional Subcutaneous Fat With Reduced Dicer and Brown Adipose Tissue Gene Expression in HIV-Infected Patients.

Published in:

2016

By:

Torriani, Martin;
Srinivasa, Suman;
Fitch, Kathleen V;
Thomou, Thomas;
Wong, Kimberly;
Petrow, Eva;
Kahn, C Ronald;
Cypess, Aaron M;
Grinspoon, Steven K

Publication type:

journal article

Deiodinase 2 expression is increased in dorsocervical fat of patients with HIV-associated lipohypertrophy syndrome.

Published in:

2012

By:

Torriani M;
Fitch K;
Stavrou E;
Bredella MA;
Lim R;
Sass CA;
Cypess AM;
Grinspoon S;
Torriani, Martin;
Fitch, Kathleen;
Stavrou, Eleni;
Bredella, Miriam A;
Lim, Ruth;
Sass, Christina A;
Cypess, Aaron M;
Grinspoon, Steven

Publication type:

journal article

Hyperinsulinemia Increases the Metabolic Clearance Rate of C-peptide.

Published in:

Diabetes, 2007, v. 56, p. A340

By:

Cypess, Aaron M.;
Lopez, Ximena;
O'shea, Sheila;
Rogatsky, Eduard;
Stein, Daniel T.;
Goldfine, Allison B.

Publication type:

Article

Insulin Sensitivity Remains Stable in Serial Studies of Healthy Patients.

Published in:

Diabetes, 2007, v. 56, p. A336

By:

Cypess, Aaron M.;
Bouche, Clara;
Fleischman, Amy;
O'Shea, Sheila;
Goldfine, Allison B.

Publication type:

Article

Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 8, p. 3339, doi. 10.1172/JCI73468

By:

Mori, Marcelo A.;
Thomou, Thomas;
Boucher, Jeremie;
Lee, Kevin Y.;
Lallukka, Susanna;
Kim, Jason K.;
Torriani, Martin;
Yki-Järvinen, Hannele;
Grinspoon, Steven K.;
Cypess, Aaron M.;
Kahn, C. Ronald

Publication type:

Article

Works by Cypess, Aaron M.

Variable Cold-Induced Brown Adipose Tissue Response to Thyroid Hormone Status.

Measurement of Skin-to-Kidney Distance in Children: Implications for Quantitative Renography.

Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin.

Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat.

Micro RNA-455 regulates brown adipogenesis via a novel HIF1an- AMPK- PGC1α signaling network.

Correction: Effect of Chronic Athletic Activity on Brown Fat in Young Women.

Effect of Chronic Athletic Activity on Brown Fat in Young Women.

The prevalence and predictors of active brown adipose tissue in Chinese adults.

Brown Adipose Tissue Activation in Humans Increases Plasma Levels of Lipid Mediators.

PET Imaging of Human Brown Adipose Tissue with the TSPO Tracer [<sup>11</sup>C]PBR28.

Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes.

Genetic and functional characterization of clonally derived adult human brown adipocytes.

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.

Pheochromocytoma and Paraganglioma Patients With Poor Survival Often Show Brown Adipose Tissue Activation.

Thyroid Hormone Effects on Glucose Disposal in Patients With Insulin Receptor Mutations.

Quantification of the Capacity for Cold-Induced Thermogenesis in Young Men With and Without Obesity.

1177-P: The Reduction in Hepatic Steatosis after Cushing's Syndrome Treatment Is a Marker of Improving Glycemia.

1701-P: The Role of UGT1a in Regulating Brown Adipose Tissue and Thermogenic Function.

1680-P: A Novel Immunomodulatory Combination That Decreases Adipose Tissue and Systemic Inflammation and Improves Metabolism in Dio Mice.

232-LB: Chronic Adrenergic Stimulation of Human Brown and White Adipose Tissue Increases Bile Acid Synthesis Enzyme Expression and Plasma Bile Acid Levels.

208-LB: Stimulation of the ß3 Adrenergic Receptors Prime Human White and Brown Adipocytes for Increased Lipolysis and Thermogenesis.

2020-P: ß3-Adrenergic Receptors Regulate Lipolysis and Thermogenesis in Human Brown/Beige Adipocytes.

137-OR: The Selective Human Beta 3 Adrenergic Receptor Mirabegron Potently Activates Lipolysis in Human White Adipocytes.

Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist.

Cellular bioenergetics as a target for obesity therapy.

Combining a β3 adrenergic receptor agonist with alpha‐lipoic acid reduces inflammation in male mice with diet‐induced obesity.

Sexual Dimorphisms in Adult Human Brown Adipose Tissue.

Diet-induced obesity causes insulin resistance in mouse brown adipose tissue.

Anatomical and Functional Assessment of Brown Adipose Tissue by Magnetic Resonance Imaging.

Quantification of Human and Rodent Brown Adipose Tissue Function Using <sup>99m</sup>Tc-Methoxyisobutylisonitrile SPECT/CT and <sup>99m</sup>F-FDG PET/CT.

Measurement of Human Brown Adipose Tissue Volume and Activity Using Anatomic MR Imaging and Functional MR Imaging.

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.

Standardized In Vitro Models of Human Adipose Tissue Reveal Metabolic Flexibility in Brown Adipocyte Thermogenesis.

Effects of lifestyle modification and metformin on irisin and FGF21 among HIV-infected subjects with the metabolic syndrome.

Dysfunctional Subcutaneous Fat With Reduced Dicer and Brown Adipose Tissue Gene Expression in HIV-Infected Patients.

Deiodinase 2 expression is increased in dorsocervical fat of patients with HIV-associated lipohypertrophy syndrome.

Hyperinsulinemia Increases the Metabolic Clearance Rate of C-peptide.

Insulin Sensitivity Remains Stable in Serial Studies of Healthy Patients.

Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.