Works by Cvekl, Ales

Results: 36

Functional interactions between alternatively spliced forms of Pax6 in crystallin gene regulation and in haploinsufficiency.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 5, p. 1696, doi. 10.1093/nar/gkh334

By:

Chauhan, Bharesh K.;
Yang, Ying;
Cveklová, Květa;
Cvekl, Aleš

Publication type:

Article

Regulation of αA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin.

Published in:

EMBO Journal, 2006, v. 25, n. 10, p. 2107, doi. 10.1038/sj.emboj.7601114

By:

Ying Yang;
Stopka, Tomáš;
Golestaneh, Nady;
Yan Wang;
Kongming Wu;
Anping Li;
Chauhan, Bharesh K.;
Gao, Chun Y.;
Cveklová, Kvšta;
Duncan, Melinda K.;
Pestell, Richard G.;
Chepelinsky, Ana B.;
Skoultchi, Arthur I.;
Cvekl, Aleš

Publication type:

Article

A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens.

Published in:

Genes to Cells, 2002, v. 7, n. 12, p. 1267, doi. 10.1046/j.1365-2443.2002.00602.x

By:

Chauhan, Bharesh K.;
Reed, Nathan A.;
Yang, Ying;
Čermák, Lukáš;
Reneker, Lixing;
Duncan, Melinda K.;
Cvekl, Aleš

Publication type:

Article

Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: role of upstream stimulatory factor.

Published in:

Genes to Cells, 2000, v. 5, n. 8, p. 661, doi. 10.1046/j.1365-2443.2000.00355.x

By:

Kirstein, Lucienne;
Cvekl, Ales;
Chauhan, Bharesh K.;
Tamm, Ernst R.

Publication type:

Article

Evolutionary Origins of Pax6 Control of Crystallin Genes.

Published in:

Genome Biology & Evolution, 2017, v. 9, n. 8, p. 2075, doi. 10.1093/gbe/evx153

By:

Cvekl, Ales;
Yilin Zhao;
McGreal, Rebecca;
Qing Xie;
Xun Gu;
Deyou Zheng

Publication type:

Article

Ectopic Norrin Induces Growth of Ocular Capillaries and Restores Normal Retinal Angiogenesis in Norrie Disease Mutant Mice.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 7, p. 1701, doi. 10.1523/JNEUROSCI.4756-04.2005

By:

Ohlmann, Andreas;
Scholz, Michael;
Goldwich, Andreas;
Chauhan, Bharesh K.;
Hudl, Kristiane;
Ohlmann, Anne V.;
Zrenner, Eberhart;
Berger, Wolfgang;
Cvekl, Aleš;
Seeliger, Mathias W.;
Tamm, Ernst R.

Publication type:

Article

Programmed mitophagy is essential for the glycolytic switch during cell differentiation.

Published in:

EMBO Journal, 2017, v. 36, n. 12, p. 1688, doi. 10.15252/embj.201695916

By:

Esteban‐Martínez, Lorena;
Sierra‐Filardi, Elena;
McGreal, Rebecca S;
Salazar‐Roa, María;
Mariño, Guillermo;
Seco, Esther;
Durand, Sylvère;
Enot, David;
Graña, Osvaldo;
Malumbres, Marcos;
Cvekl, Ales;
Cuervo, Ana María;
Kroemer, Guido;
Boya, Patricia

Publication type:

Article

Efficient generation of lens progenitor cells and lentoid bodies from human embryonic stem cells in chemically defined conditions.

Published in:

FASEB Journal, 2010, v. 24, n. 9, p. 3274, doi. 10.1096/fj.10-157255

By:

Yang, Chunbo;
Yang, Ying;
Brennan, Lisa;
Bouhassira, Eric E.;
Kantorow, Marc;
Cvekl, Ales

Publication type:

Article

Palm is expressed in both developing and adult mouse lens and retina.

Published in:

BMC Ophthalmology, 2005, v. 5, p. 14, doi. 10.1186/1471-2415-5-14

By:

Castellini, Meryl;
Wolf, Louise V.;
Chauhan, Bharesh K.;
Galileo, Deni S.;
Kilimann, Manfred W.;
Cvekl, Ales;
Duncan, Melinda K.

Publication type:

Article

A distal enhancer that directs Otx2 expression in the retinal pigment epithelium and neuroretina.

Published in:

Developmental Dynamics, 2020, v. 249, n. 2, p. 209, doi. 10.1002/dvdy.127

By:

Bhansali, Punita;
Cvekl, Ales;
Liu, Wei

Publication type:

Article

Identification of Novel Gata3 Distal Enhancers Active in Mouse Embryonic Lens.

Published in:

Developmental Dynamics, 2018, v. 247, n. 11, p. 1186, doi. 10.1002/dvdy.24677

By:

Martynova, Elena;
Bouchard, Maxime;
Musil, Linda S.;
Cvekl, Ales

Publication type:

Article

Cell autonomous roles for AP-2α in lens vesicle separation and maintenance of the lens epithelial cell phenotype.

Published in:

Developmental Dynamics, 2008, v. 237, n. 3, p. 602, doi. 10.1002/dvdy.21445

By:

Pontoriero, Giuseppe F.;
Deschamps, Paula;
Ashery-Padan, Ruth;
Wong, Ryan;
Yang, Ying;
Zavadil, Jiri;
Cvekl, Ales;
Sullivan, Shelley;
Williams, Trevor;
West-Mays, Judith A.

Publication type:

Article

Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases.

Published in:

BioEssays, 2004, v. 26, n. 4, p. 374, doi. 10.1002/bies.20009

By:

Cvekl, Aleš;
Tamm, Ernst R.

Publication type:

Article

Lens development and crystallin gene expression: Many role for Pax-6.

Published in:

BioEssays, 1996, v. 18, n. 8, p. 621, doi. 10.1002/bies.950180805

By:

Cvekl, Ales;
Piatigorsky, Joram

Publication type:

Article

Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways.

Published in:

Epigenetics & Chromatin, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13072-019-0272-y

By:

Zhao, Yilin;
Zheng, Deyou;
Cvekl, Ales

Publication type:

Article

Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers.

Published in:

Epigenetics & Chromatin, 2016, v. 8, p. 1, doi. 10.1186/s13072-016-0087-z

By:

Jian Sun;
Yilin Zhao;
McGreal, Rebecca;
Cohen-Tayar, Yamit;
Rockowitz, Shira;
Wilczek, Carola;
Ashery-Padan, Ruth;
Shechter, David;
Deyou Zheng;
Cvekl, Ales

Publication type:

Article

Chromatin remodeling enzyme Brg1 is requiredfor mouse lens fiber cell terminal differentiationand its denucleation.

Published in:

Epigenetics & Chromatin, 2010, v. 3, p. 21, doi. 10.1186/1756-8935-3-21

By:

Shuying He;
Pirity, Melinda K.;
Wei-Lin Wang;
Wolf, Louise;
Chauhan, Bharesh K.;
Cveklova, Kveta;
Tamm, Ernst R.;
Ashery-Padan, Ruth;
Metzger, Daniel;
Nakai, Akira;
Chambon, Pierre;
Zavadil, Jiri;
Cvekl, Ales

Publication type:

Article

Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers.

Published in:

Epigenetics & Chromatin, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13072-024-00533-x

By:

Camerino, Michael;
Chang, William;
Cvekl, Ales

Publication type:

Article

Dynamic changes in whole genome DNA methylation, chromatin and gene expression during mouse lens differentiation.

Published in:

Epigenetics & Chromatin, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13072-023-00478-7

By:

Chang, William;
Zhao, Yilin;
Rayêe, Danielle;
Xie, Qing;
Suzuki, Masako;
Zheng, Deyou;
Cvekl, Ales

Publication type:

Article

Large Maf Transcription Factors: Cousins of AP-1 Proteins and Important Regulators of Cellular Differentiation.

Published in:

Einstein Journal of Biology & Medicine, 2007, v. 23, n. 1, p. 2

By:

Ying Yang;
Cvekl, Ales

Publication type:

Article

Identification of in vivoDNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 14, p. 6827, doi. 10.1093/nar/gkv589

By:

Jian Sun;
Rockowitz, Shira;
Qing Xie;
Ashery-Padan, Ruth;
Deyou Zheng;
Cvekl, Ales

Publication type:

Article

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 22, p. 10199, doi. 10.1093/nar/gkt824

By:

Wolf, Louise;
Harrison, Wilbur;
Huang, Jie;
Xie, Qing;
Xiao, Ningna;
Sun, Jian;
Kong, Lingkun;
Lachke, Salil A.;
Kuracha, Murali R.;
Govindarajan, Venkatesh;
Brindle, Paul K.;
Ashery-Padan, Ruth;
Beebe, David C.;
Overbeek, Paul A.;
Cvekl, Ales

Publication type:

Article

Mammalian TBX1 Preferentially Binds and Regulates Downstream Targets Via a Tandem T-site Repeat.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0095151

By:

Castellanos, Raquel;
Xie, Qing;
Zheng, Deyou;
Cvekl, Ales;
Morrow, Bernice E.

Publication type:

Article

Pax6 Interactions with Chromatin and Identification of Its Novel Direct Target Genes in Lens and Forebrain.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054507

By:

Qing Xie;
Ying Yang;
Jie Huang;
Ninkovic, Jovica;
Walcher, Tessa;
Wolf, Louise;
Vitenzon, Ariel;
Deyou Zheng;
Götz, Magdalena;
Beebe, David C.;
Zavadil, Jiri;
Cvekl, Ales

Publication type:

Article

Perturbing the Ubiquitin Pathway Reveals How Mitosis Is Hijacked to Denucleate and Regulate Cell Proliferation and Differentiation In Vivo.

Published in:

PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013331

By:

Caceres, Andrea;
Fu Shang;
Wawrousek, Eric;
Qing Liu;
Avidan, Orna;
Cvekl, Ales;
Ying Yang;
Haririnia, Aydin;
Storaska, Andrew;
Fushman, David;
Kuszak, Jer;
Dudek, Edward;
Smith, Donald;
Taylor, Allen

Publication type:

Article

Identification of Pax6-Dependent Gene Regulatory Networks in the Mouse Lens.

Published in:

PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004159

By:

Wolf, Louise V.;
Ying Yang;
Jinhua Wang;
Qing Xie;
Braunger, Barbara;
Tamm, Ernst R.;
Zavadil, Jiri;
Cvekl, Ales

Publication type:

Article

Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204.

Published in:

PLoS Genetics, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.pgen.1003357

By:

Shaham, Ohad;
Gueta, Karen;
Mor, Eyal;
Oren-Giladi, Pazit;
Grinberg, Dina;
Qing Xie;
Cvekl, Ales;
Shomron, Noam;
Davis, Noa;
Keydar-Prizant, Maya;
Raviv, Shaul;
Pasmanik-Chor, Metsada;
Bell, Rachel E.;
Levy, Carmit;
Avellino, Raffaella;
Banfi, Sandro;
Conte, Ivan;
Ashery-Padan, Ruth

Publication type:

Article

Generation of Lens Progenitor Cells and Lentoid Bodies from Pluripotent Stem Cells: Novel Tools for Human Lens Development and Ocular Disease Etiology.

Published in:

Cells (2073-4409), 2022, v. 11, n. 21, p. 3516, doi. 10.3390/cells11213516

By:

Cvekl, Aleš;
Camerino, Michael John

Publication type:

Article

Multi ‐ omics studies of eye and lens development.

Published in:

2024

By:

Cvekl, Ales

Publication type:

Abstract

Genetic coding of lens fibre cell differentiation.

Published in:

2022

By:

Cvekl, Ales

Publication type:

Abstract

Chromatin dynamics, DNA‐binding transcription factors and lens differentiation.

Published in:

Acta Ophthalmologica (1755375X), 2019, v. 97, p. N.PAG, doi. 10.1111/j.1755-3768.2019.8018

By:

Cvekl, Ales

Publication type:

Article

Analysis of transcription by ChIP‐seq in the eye: Progress and challenges.

Published in:

Acta Ophthalmologica (1755375X), 2019, v. 97, p. N.PAG, doi. 10.1111/j.1755-3768.2019.5002

By:

Cvekl, Ales

Publication type:

Article

Multiomics Analysis Reveals Novel Genetic Determinants for Lens Differentiation, Structure, and Transparency.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 4, p. 693, doi. 10.3390/biom13040693

By:

Disatham, Joshua;
Brennan, Lisa;
Cvekl, Ales;
Kantorow, Marc

Publication type:

Article

Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract.

Published in:

FASEB Journal, 2016, v. 30, n. 3, p. 1087, doi. 10.1096/fj.15-278036

By:

Lei Lyu;
Whitcomb, Elizabeth A.;
Shuhong Jiang;
Min-Lee Chang;
Yumei Gu;
Duncan, Melinda K.;
Cvekl, Ales;
Wei-Lin Wang;
Saima Limi;
Reneker, Lixing W.;
Fu Shang;
Linfang Du;
Taylor, Allen

Publication type:

Article

Transcriptional regulation of mouse alpha A-crystallin gene in a 148kb Cryaa BAC and its derivates.

Published in:

BMC Developmental Biology, 2008, v. 8, p. 1, doi. 10.1186/1471-213X-8-88

By:

Wolf, Louise;
Ying Yang;
Wawrousek, Eric;
Cvekl, Ales

Publication type:

Article

Rybp, a polycomb complex-associated protein, is required for mouse eye development.

Published in:

BMC Developmental Biology, 2007, v. 7, p. 39, doi. 10.1186/1471-213X-7-39

By:

Pirity, Melinda K.;
Wei-Lin Wang;
Wolf, Louise V.;
Tamm, Ernst R.;
Schreiber-Agus, Nicole;
Cvekl, Ales

Publication type:

Article