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An Immunconjugate Vaccine Alters Distribution and Reduces the Antinociceptive, Behavioral and Physiological Effects of Fentanyl in Male and Female Rats.
Published in:
Pharmaceutics, 2022, v. 14, n. 11, p. 2290, doi. 10.3390/pharmaceutics14112290
By:
- Haile, Colin N.;
- Baker, Miah D.;
- Sanchez, Sergio A.;
- Lopez Arteaga, Carlos A.;
- Duddupudi, Anantha L.;
- Cuny, Gregory D.;
- Norton, Elizabeth B.;
- Kosten, Thomas R.;
- Kosten, Therese A.
Publication type:
Article
Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds.
Published in:
EMBO Molecular Medicine, 2013, v. 5, n. 7, p. 1035, doi. 10.1002/emmm.201202305
By:
- Cherry, Jonathan J.;
- Osman, Erkan Y.;
- Evans, Matthew C.;
- Choi, Sungwoon;
- Xing, Xuechao;
- Cuny, Gregory D.;
- Glicksman, Marcie A.;
- Lorson, Christian L.;
- Androphy, Elliot J.
Publication type:
Article
A Mild, One-Pot Stadler-Ziegler Synthesis of Arylsulfides Facilitated by Photoredox Catalysis in Batch and Continuous-Flow.
Published in:
Angewandte Chemie International Edition, 2013, v. 52, n. 30, p. 7860, doi. 10.1002/anie.201303483
By:
- Wang, Xiao;
- Cuny, Gregory D.;
- Noël, Timothy
Publication type:
Article
A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex.
Published in:
PLoS Pathogens, 2023, v. 19, n. 11, p. 1, doi. 10.1371/journal.ppat.1011781
By:
- Chen, Han;
- Lye, Ming F.;
- Gorgulla, Christoph;
- Ficarro, Scott B.;
- Cuny, Gregory D.;
- Scott, David A.;
- Wu, Fan;
- Rothlauf, Paul W.;
- Wang, Xiaoou;
- Fernandez, Rosio;
- Pesola, Jean M.;
- Draga, Sorin;
- Marto, Jarrod A.;
- Hogle, James M.;
- Arthanari, Haribabu;
- Coen, Donald M.
Publication type:
Article
Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 3, p. 1255, doi. 10.1172/JCI66163
By:
- Qiongman Kong;
- Ling-Chu Chang;
- Kou Takahashi;
- Qibing Liu;
- Schulte, Delanie A.;
- Liching Lai;
- Ibabao, Brian;
- Yuchen Lin;
- Stouffer, Nathan;
- Das Mukhopadhyay, Chitra;
- Xuechao Xing;
- Seyb, Kathleen I.;
- Cuny, Gregory D.;
- Glicksman, Marcie A.;
- Chien-Liang Glenn Lin
Publication type:
Article
Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 5, p. 531, doi. 10.1107/S2053230X15000187
By:
- Kim, Youngchang;
- Makowska-Grzyska, Magdalena;
- Gorla, Suresh Kumar;
- Gollapalli, Deviprasad R.;
- Cuny, Gregory D.;
- Joachimiak, Andrzej;
- Hedstrom, Lizbeth
Publication type:
Article
Erratum: BMP type I receptor inhibition reduces heterotopic ossification.
Published in:
2009
By:
- Yu, Paul B;
- Deng, Donna Y;
- Lai, Carol S;
- Hong, Charles C;
- Cuny, Gregory D;
- Bouxsein, Mary L;
- Hong, Deborah W;
- McManus, Patrick M;
- Katagiri, Takenobu;
- Sachidanandan, Chetana;
- Kamiya, Nobuhiro;
- Fukuda, Tomokazu;
- Mishina, Yuji;
- Peterson, Randall T;
- Bloch, Kenneth D
Publication type:
Correction Notice
BMP type I receptor inhibition reduces heterotopic ossification.
Published in:
Nature Medicine, 2008, v. 14, n. 12, p. 1363, doi. 10.1038/nm.1888
By:
- Yu, Paul B.;
- Deng, Donna Y.;
- Lai, Carol S.;
- Hong, Charles C.;
- Cuny, Gregory D.;
- Bouxsein, Mary L.;
- Hong, Deborah W.;
- McManus, Patrick M.;
- Katagiri, Takenobu;
- Sachidanandan, Chetana;
- Kamiya, Nobuhiro;
- Fukuda, Tomokazu;
- Mishina, Yuji;
- Peterson, Randall T.;
- Bloch, Kenneth D.
Publication type:
Article
Fused s-triazino heterocycles. XVII. 8,13-Dihydro-1,3,7,8,13c-pentaazabenzo[ de]naphthacene, 7 H-1,3,7,8,11b,12,14-heptaazadibenzo[ de,hi]naphthacene and 8 H-1,3,7,8,13,14c-hexaazabenzo[4,5]cyclohepta[1,2- a]phenalene, three new ring systems.
Published in:
Journal of Heterocyclic Chemistry, 1991, v. 28, n. 4, p. 987, doi. 10.1002/jhet.5570280425
By:
- Shaw, John T.;
- Corbett, Wendy L.;
- Cuny, Gregory D.;
- Egler, Mallory F.;
- Peciulis, Victoria S.
Publication type:
Article
A Mild, One-Pot Stadler-Ziegler Synthesis of Arylsulfides Facilitated by Photoredox Catalysis in Batch and Continuous-Flow.
Published in:
Angewandte Chemie, 2013, v. 125, n. 30, p. 8014, doi. 10.1002/ange.201303483
By:
- Wang, Xiao;
- Cuny, Gregory D.;
- Noël, Timothy
Publication type:
Article
Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0138976
By:
- Makowska-Grzyska, Magdalena;
- Kim, Youngchang;
- Gorla, Suresh Kumar;
- Wei, Yang;
- Mandapati, Kavitha;
- Zhang, Minjia;
- Maltseva, Natalia;
- Modi, Gyan;
- Boshoff, Helena I.;
- Gu, Minyi;
- Aldrich, Courtney;
- Cuny, Gregory D.;
- Hedstrom, Lizbeth;
- Joachimiak, Andrzej
Publication type:
Article
A New Class of Small Molecule Inhibitor of BMP Signaling.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062721
By:
- Sanvitale, Caroline E.;
- Kerr, Georgina;
- Chaikuad, Apirat;
- Ramel, Marie-Christine;
- Mohedas, Agustin H.;
- Reichert, Sabine;
- Wang, You;
- Triffitt, James T.;
- Cuny, Gregory D.;
- Yu, Paul B.;
- Hill, Caroline S.;
- Bullock, Alex N.
Publication type:
Article
Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0056576
By:
- McNamara, Colleen R.;
- Ahuja, Ruchita;
- Osafo-Addo, Awo D.;
- Barrows, Douglas;
- Kettenbach, Arminja;
- Skidan, Igor;
- Teng, Xin;
- Cuny, Gregory D.;
- Gerber, Scott;
- Degterev, Alexei
Publication type:
Article
Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin.
Published in:
PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010504
By:
- Leissring, Malcolm A.;
- Malito, Enrico;
- Hedouin, Sabrine;
- Reinstatler, Lael;
- Sahara, Tomoko;
- Abdul-Hay, Samer O.;
- Choudhry, Shakeel;
- Maharvi, Ghulam M.;
- Fauq, Abdul H.;
- Huzarska, Malwina;
- May, Philip S.;
- Sungwoon Choi;
- Logan, Todd P.;
- Turk, Benjamin E.;
- Cantley, Lewis C.;
- Manolopoulou, Marika;
- Wei-Jen Tang;
- Stein, Ross L.;
- Cuny, Gregory D.;
- Selkoe, Dennis J.
Publication type:
Article
Small-Molecule Activators of Insulin-Degrading Enzyme Discovered through High-Throughput Compound Screening.
Published in:
PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005274
By:
- Cabrol, Christelle;
- Huzarska, Malwina A.;
- Dinolfo, Christopher;
- Rodriguez, Maria C.;
- Reinstatler, Lael;
- Ni, Jake;
- Li-An Yeh;
- Cuny, Gregory D.;
- Stein, Ross L.;
- Selkoe, Dennis J.;
- Leissring, Malcolm A.
Publication type:
Article
Rhodium-Catalyzed Hydroformylation of Internal Alkynes to α,β-Unsaturated Aldehydes.
Published in:
Angewandte Chemie International Edition, 1995, v. 34, n. 16, p. 1760, doi. 10.1002/anie.199517601
By:
- Johnson, John R.;
- Cuny, Gregory D.;
- Buchwald, Stephen L.
Publication type:
Article
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.
Published in:
EMBO Journal, 2018, v. 37, n. 17, p. 1, doi. 10.15252/embj.201899372
By:
- Hrdinka, Matous;
- Schlicher, Lisa;
- Dai, Bing;
- Pinkas, Daniel M.;
- Bufton, Joshua C.;
- Picaud, Sarah;
- Ward, Jennifer A.;
- Rogers, Catherine;
- Suebsuwong, Chalada;
- Nikhar, Sameer;
- Cuny, Gregory D.;
- Huber, Kilian V. M.;
- Filippakopoulos, Panagis;
- Bullock, Alex N.;
- Degterev, Alexei;
- Gyrd‐Hansen, Mads
Publication type:
Article
Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2008, v. 28, n. 9, p. 1564, doi. 10.1038/jcbfm.2008.44
By:
- You, Zerong;
- Savitz, Sean I.;
- Yang, Jinsheng;
- Degterev, Alexei;
- Yuan, Junying;
- Cuny, Gregory D.;
- Moskowitz, Michael A.;
- Whalen, Michael J.
Publication type:
Article
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor.
Published in:
Cell Death & Disease, 2021, v. 12, n. 7, p. 1, doi. 10.1038/s41419-021-03994-0
By:
- Delanghe, Tom;
- Huyghe, Jon;
- Lee, Seungheon;
- Priem, Dario;
- Van Coillie, Samya;
- Gilbert, Barbara;
- Choi, Sze Men;
- Vandenabeele, Peter;
- Degterev, Alexei;
- Cuny, Gregory D.;
- Dondelinger, Yves;
- Bertrand, Mathieu J. M.
Publication type:
Article
Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease.
Published in:
PLoS Biology, 2014, v. 12, n. 8, p. 1, doi. 10.1371/journal.pbio.1001923
By:
- Xu, Jian;
- Chatterjee, Manavi;
- Baguley, Tyler D.;
- Brouillette, Jonathan;
- Kurup, Pradeep;
- Ghosh, Debolina;
- Kanyo, Jean;
- Zhang, Yang;
- Seyb, Kathleen;
- Ononenyi, Chimezie;
- Foscue, Ethan;
- Anderson, George M.;
- Gresack, Jodi;
- Cuny, Gregory D.;
- Glicksman, Marcie A.;
- Greengard, Paul;
- Lam, TuKiet T.;
- Tautz, Lutz;
- Nairn, Angus C.;
- Ellman, Jonathan A.
Publication type:
Article
Fentanyl conjugate vaccine by injected or mucosal delivery with dmLT or LTA1 adjuvants implicates IgA in protection from drug challenge.
Published in:
NPJ Vaccines, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41541-021-00329-0
By:
- Stone, Addison E.;
- Scheuermann, Sarah E.;
- Haile, Colin N.;
- Cuny, Gregory D.;
- Velasquez, Marcela Lopez;
- Linhuber, Joshua P.;
- Duddupudi, Anantha L.;
- Vigliaturo, Jennifer R.;
- Pravetoni, Marco;
- Kosten, Therese A.;
- Kosten, Thomas R.;
- Norton, Elizabeth B.
Publication type:
Article
8-, 9-, and 11-Aryloxy Dimeric Aporphines and Their Pharmacological Activities.
Published in:
Molecules, 2021, v. 26, n. 15, p. 4521, doi. 10.3390/molecules26154521
By:
- Ali, Ghada;
- Cuny, Gregory D.
Publication type:
Article
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Published in:
Nature Chemical Biology, 2013, v. 9, n. 3, p. 192, doi. 10.1038/nchembio0313-192a
By:
- Degterev, Alexei;
- Huang, Zhihong;
- Boyce, Michael;
- Li, Yaqiao;
- Jagtap, Prakash;
- Mizushima, Noboru;
- Cuny, Gregory D;
- Mitchison, Timothy J;
- Moskowitz, Michael A;
- Yuan, Junying
Publication type:
Article
Identification of RIP1 kinase as a specific cellular target of necrostatins.
Published in:
Nature Chemical Biology, 2008, v. 4, n. 5, p. 313, doi. 10.1038/nchembio.83
By:
- Degterev, Alexei;
- Hitomi, Junichi;
- Germscheid, Megan;
- Ch'en, Irene L.;
- Korkina, Olga;
- Xin Teng;
- Abbott, Derek;
- Cuny, Gregory D.;
- Chengye Yuan;
- Wagner, Gerhard;
- Hedrick, Stephen M.;
- Gerber, Scott A.;
- Lugovskoy, Alexey;
- Junying Yuan
Publication type:
Article
Corrigendum: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Published in:
2005
By:
- Degterev, Alexei;
- Zhihong Huang;
- Boyce, Michael;
- Yaqiao Li;
- Jagtap, Prakash;
- Mizushima, Noboru;
- Cuny, Gregory D.;
- Mitchison, Timothy J.;
- Moskowitz, Michael A.;
- Junying Yuan
Publication type:
Correction Notice
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Published in:
Nature Chemical Biology, 2005, v. 1, n. 2, p. 112, doi. 10.1038/nchembio711
By:
- Degterev, Alexei;
- Zhihong Huang;
- Boyce, Michael;
- Yaqiao Li;
- Jagtap, Prakash;
- Noboru Mizushima;
- Cuny, Gregory D.;
- Mitchison, Timothy J.;
- Moskowitz, Michael A.;
- Junying Yuan
Publication type:
Article

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