Works by Cucchiarini, Magali

Results: 142

Advances and challenges in gene-based approaches for osteoarthritis.

Published in:

Journal of Gene Medicine, 2013, v. 15, n. 10, p. 343, doi. 10.1002/jgm.2741

By:

Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Effective, safe nonviral gene transfer to preserve the chondrogenic differentiation potential of human mesenchymal stem cells.

Published in:

Journal of Gene Medicine, 2012, v. 14, n. 7, p. 501, doi. 10.1002/jgm.2644

By:

Elsler, Sebastian;
Schetting, Sarah;
Schmitt, Gertrud;
Kohn, Dieter;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Evaluation of nonbiomedical and biomedical grade alginates for the transplantation of genetically modified articular chondrocytes to cartilage defects in a large animal model in vivo.

Published in:

Journal of Gene Medicine, 2011, v. 13, n. 4, p. 230, doi. 10.1002/jgm.1557

By:

Heiligenstein, Susanne;
Cucchiarini, Magali;
Laschke, Matthias W.;
Bohle, Rainer M.;
Kohn, Dieter;
Menger, Michael D.;
Madry, Henning

Publication type:

Article

Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo.

Published in:

Journal of Gene Medicine, 2006, v. 8, n. 1, p. 100, doi. 10.1002/jgm.819

By:

Kaul, Gunter;
Cucchiarini, Magali;
Arntzen, David;
Zurakowski, David;
Menger, Michael D.;
Kohn, Dieter;
Trippel, Stephen B;
Madry, Henning

Publication type:

Article

Gene therapy for cartilage defects.

Published in:

Journal of Gene Medicine, 2005, v. 7, n. 12, p. 1495, doi. 10.1002/jgm.824

By:

Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system.

Published in:

Journal of Gene Medicine, 2003, v. 5, n. 6, p. 502, doi. 10.1002/jgm.368

By:

Madry, Henning;
Cucchiarini, Magali;
Stein, Ute;
Remberger, Klaus;
Menger, Michael D.;
Kohn, Dieter;
Trippel, Stephen B.

Publication type:

Article

Secretome and Extracellular Vesicles as New Biological Therapies for Knee Osteoarthritis: A Systematic Review.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1867, doi. 10.3390/jcm8111867

By:

D'Arrigo, Daniele;
Roffi, Alice;
Cucchiarini, Magali;
Moretti, Matteo;
Candrian, Christian;
Filardo, Giuseppe

Publication type:

Article

Association of Nicotine with Osteochondrogenesis and Osteoarthritis Development: The State of the Art of Preclinical Research.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1699, doi. 10.3390/jcm8101699

By:

Cai, Xiaoyu;
Gao, Liang;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1637, doi. 10.3390/jcm8101637

By:

Daniels, Oliver;
Frisch, Janina;
Venkatesan, Jagadeesh K.;
Rey-Rico, Ana;
Schmitt, Gertrud;
Cucchiarini, Magali

Publication type:

Article

Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 9, p. 1326, doi. 10.3390/jcm8091326

By:

Morscheid, Stephanie;
Venkatesan, Jagadeesh Kumar;
Rey-Rico, Ana;
Schmitt, Gertrud;
Cucchiarini, Magali

Publication type:

Article

Translational applications of photopolymerizable hydrogels for cartilage repair.

Published in:

Journal of Experimental Orthopaedics, 2019, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40634-019-0215-3

By:

Meng, Weikun;
Gao, Liang;
Venkatesan, Jagadeesh K.;
Wang, Guanglin;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Effects of rAAV-Mediated Overexpression of sox9 and TGF-ß via Alginate Hydrogel-Guided Vector Delivery on the Chondroreparative Activities of Human Bone Marrow-Derived Mesenchymal Stromal Cells.

Published in:

Journal of Tissue Engineering & Regenerative Medicine, 2023, p. 1, doi. 10.1155/2023/4495697

By:

Liu, Wei;
Venkatesan, Jagadeesh K.;
Amini, Mahnaz;
Oláh, Tamás;
Schmitt, Gertrud;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Enamel matrix derivative inhibits proteoglycan production and articular cartilage repair, delays the restoration of the subchondral bone and induces changes of the synovial membrane in a lapine osteochondral defect model in vivo.

Published in:

Journal of Tissue Engineering & Regenerative Medicine, 2014, v. 8, n. 1, p. 41, doi. 10.1002/term.1495

By:

Kiss, Alice;
Cucchiarini, Magali;
Menger, Michael D.;
Kohn, Dieter;
Hannig, Matthias;
Madry, Henning

Publication type:

Article

rAAV-mediated overexpression of TGF-ß via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model.

Published in:

International Journal of Nanomedicine, 2017, v. 12, p. 6985, doi. 10.2147/IJN.S144579

By:

Rey-Rico, Ana;
Venkatesan, Jagadeesh K.;
Schmitt, Gertrud;
Concheiro, Angel;
Madry, Henning;
Alvarez-Lorenzo, Carmen;
Cucchiarini, Magali

Publication type:

Article

Correction: Hosseinikha et al. Nanomaterials for the Diagnosis and Treatment of Inflammatory Arthritis. Int. J. Mol. Sci. 2021, 22 , 3092.

Published in:

2025

By:

Hosseinikhah, Seyedeh Maryam;
Barani, Mahmood;
Rahdar, Abbas;
Madry, Henning;
Arshad, Rabia;
Mohammadzadeh, Vahideh;
Cucchiarini, Magali

Publication type:

Correction Notice

Analysis of Novel Nonviral Gene Transfer Systems for Gene Delivery to Cells of the Musculoskeletal System.

Published in:

Molecular Biotechnology, 2008, v. 38, n. 2, p. 137, doi. 10.1007/s12033-007-0071-8

By:

Orth, Patrick;
Weimer, Anja;
Kaul, Gunter;
Kohn, Dieter;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Current perspectives in stem cell research for knee cartilage repair.

Published in:

Stem Cells & Cloning: Advances & Applications, 2014, v. 7, p. 1, doi. 10.2147/SCCAA.S42880

By:

Orth, Patrick;
Rey-Rico, Ana;
Venkatesan, Jagadeesh K.;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Sustained spatiotemporal release of TGF-β1 confers enhanced very early chondrogenic differentiation during osteochondral repair in specific topographic patterns.

Published in:

FASEB Journal, 2018, v. 32, n. 10, p. 5298, doi. 10.1096/fj.201800105R

By:

Asen, Ann-Kathrin;
Goebel, Lars;
Rey-Rico, Ana;
Sohier, Jerome;
Zurakowski, David;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Clinical potential and challenges of using genetically modified cells for articular cartilage repair.

Published in:

Croatian Medical Journal, 2011, v. 52, n. 3, p. 245, doi. 10.3325/cmj.2011.52.245

By:

Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Genetic Modification of Human Peripheral Blood Aspirates Using Recombinant Adeno-Associated Viral Vectors for Articular Cartilage Repair with a Focus on Chondrogenic Transforming Growth Factor-β Gene Delivery.

Published in:

Stem Cells Translational Medicine, 2017, v. 6, n. 1, p. 249, doi. 10.5966/sctm.2016-0149

By:

Frisch, Janina;
Orth, Patrick;
Venkatesan, Jagadeesh Kumar;
Rey-Rico, Ana;
Schmitt, Gertrud;
Kohn, Dieter;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Recent tissue engineering-based advances for effective rAAV-mediated gene transfer in the musculoskeletal system.

Published in:

Bioengineered, 2016, v. 7, n. 3, p. 175, doi. 10.1080/21655979.2016.1187347

By:

Rey-Rico, Ana;
Cucchiarini, Magali

Publication type:

Article

A high‐resolution cross‐species comparative analysis of the subchondral bone provides insight into critical topographical patterns of the osteochondral unit.

Published in:

Clinical & Translational Medicine, 2022, v. 12, n. 2, p. 1, doi. 10.1002/ctm2.745

By:

Michaelis, Jana Christin;
Oláh, Tamás;
Schrenker, Steffen;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Therapeutic Controlled Release Strategies for Human Osteoarthritis.

Published in:

Advanced Healthcare Materials, 2025, v. 14, n. 2, p. 1, doi. 10.1002/adhm.202402737

By:

Wang, Dan;
Liu, Wei;
Venkatesan, Jagadeesh K.;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

A Photopolymerizable Biocompatible Hyaluronic Acid Hydrogel Promotes Early Articular Cartilage Repair in a Minipig Model In Vivo.

Published in:

Advanced Healthcare Materials, 2023, v. 12, n. 26, p. 1, doi. 10.1002/adhm.202300931

By:

Gao, Liang;
Beninatto, Riccardo;
Oláh, Tamás;
Goebel, Lars;
Tao, Ke;
Roels, Rebecca;
Schrenker, Steffen;
Glomm, Julianne;
Venkatesan, Jagadeesh K.;
Schmitt, Gertrud;
Sahin, Ebrar;
Dahhan, Ola;
Pavan, Mauro;
Barbera, Carlo;
Lucia, Alba Di;
Menger, Michael D.;
Laschke, Matthias W.;
Cucchiarini, Magali;
Galesso, Devis;
Madry, Henning

Publication type:

Article

Axial alignment is a critical regulator of knee osteoarthritis.

Published in:

Science Translational Medicine, 2022, v. 14, n. 629, p. 1, doi. 10.1126/scitranslmed.abn0179

By:

Oláh, Tamás;
Reinhard, Jan;
Laschke, Matthias W.;
Goebel, Lars K. H.;
Walter, Frédéric;
Schmitt, Gertrud;
Speicher-Mentges, Susanne;
Menger, Michael D.;
Cucchiarini, Magali;
Pape, Dietrich;
Madry, Henning

Publication type:

Article

Analysis of spatial osteochondral heterogeneity in advanced knee osteoarthritis exposes influence of joint alignment.

Published in:

Science Translational Medicine, 2020, v. 12, n. 562, p. 1, doi. 10.1126/scitranslmed.aba9481

By:

Haberkamp, Sophie;
Oláh, Tamás;
Orth, Patrick;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Topographic modeling of early human osteoarthritis in sheep.

Published in:

Science Translational Medicine, 2019, v. 11, n. 508, p. 1, doi. 10.1126/scitranslmed.aax6775

By:

Oláh, Tamás;
Reinhard, Jan;
Gao, Liang;
Haberkamp, Sophie;
Goebel, Lars K. H.;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Design of Mannose-Coated Rifampicin nanoparticles modulating the immune response and Rifampicin induced hepatotoxicity with improved oral drug delivery.

Published in:

Arabian Journal of Chemistry, 2021, v. 14, n. 9, p. N.PAG, doi. 10.1016/j.arabjc.2021.103321

By:

Rauf, Aisha;
Tabish, Tanveer A.;
Ibrahim, Ibrahim M;
Rauf ul Hassan, Muhammad;
Tahseen, Sabira;
Abdullah Sandhu, Mansoor;
Shahnaz, Gul;
Rahdar, Abbas;
Cucchiarini, Magali;
Pandey, Sadanand

Publication type:

Article

Phytochemical and nutra-pharmaceutical attributes of Mentha spp.: A comprehensive review.

Published in:

Arabian Journal of Chemistry, 2021, v. 14, n. 5, p. N.PAG, doi. 10.1016/j.arabjc.2021.103106

By:

Eftekhari, Aziz;
Khusro, Ameer;
Ahmadian, Elham;
Dizaj, Solmaz Maleki;
Hasanzadeh, Amir;
Cucchiarini, Magali

Publication type:

Article

rAAV Vectors as Safe and Efficient Tools for the Stable Delivery of Genes to Primary Human Chondrosarcoma Cells In Vitro and In Situ.

Published in:

2012

By:

Madry, Henning;
Venkatesan, Jagadeesh K.;
Schmitt, Gertrud;
Schetting, Sarah;
Ekici, Myriam;
Kohn, Dieter;
Cucchiarini, Magali

Publication type:

Journal Article

rAAV Vectors as Safe and Efficient Tools for the Stable Delivery of Genes to Primary Human Chondrosarcoma Cells In Vitro and In Situ.

Published in:

Sarcoma, 2012, p. 1, doi. 10.1155/2012/347417

By:

Madry, Henning;
Venkatesan, Jagadeesh K.;
Schmitt, Gertrud;
Schetting, Sarah;
Ekici, Myriam;
Kohn, Dieter;
Cucchiarini, Magali

Publication type:

Article

The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.

Published in:

2015

By:

Joshi, Yashashree;
Sória, Marília Grando;
Quadrato, Giorgia;
Inak, Gizem;
Zhou, Luming;
Hervera, Arnau;
Rathore, Khizr I.;
Elnaggar, Mohamed;
Cucchiarini, Magali;
Marine, Jeanne Christophe;
Puttagunta, Radhika;
Di Giovanni, Simone

Publication type:

journal article

rAAV-mediated combined gene transfer and overexpression of TGF-β and SOX9 remodels human osteoarthritic articular cartilage.

Published in:

Journal of Orthopaedic Research, 2016, v. 34, n. 12, p. 2181, doi. 10.1002/jor.23228

By:

Tao, Ke;
Rey‐Rico, Ana;
Frisch, Janina;
Venkatesan, Jagadeesh K.;
Schmitt, Gertrud;
Madry, Henning;
Lin, Jianhao;
Cucchiarini, Magali

Publication type:

Article

Improved repair of chondral and osteochondral defects in the ovine trochlea compared with the medial condyle.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 11, p. 1772, doi. 10.1002/jor.22418

By:

Orth, Patrick;
Meyer, Heinz‐Lothar;
Goebel, Lars;
Eldracher, Mona;
Ong, Mei Fang;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Adapted chondrogenic differentiation of human mesenchymal stem cells via controlled release of TGF-β1 from poly(ethylene oxide)-terephtalate/poly(butylene terepthalate) multiblock scaffolds.

Published in:

Journal of Biomedical Materials Research, Part A, 2015, v. 103, n. 1, p. 371, doi. 10.1002/jbm.a.35181

By:

Rey‐Rico, Ana;
Venkatesan, Jagadeesh K.;
Sohier, Jerome;
Moroni, Lorenzo;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Thermosensitive Hydrogel Based on PEO–PPO–PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno‐Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects.

Published in:

Advanced Materials, 2020, v. 32, n. 2, p. N.PAG, doi. 10.1002/adma.201906508

By:

Madry, Henning;
Gao, Liang;
Rey‐Rico, Ana;
Venkatesan, Jagadeesh K.;
Müller‐Brandt, Kathrin;
Cai, Xiaoyu;
Goebel, Lars;
Schmitt, Gertrud;
Speicher‐Mentges, Susanne;
Zurakowski, David;
Menger, Michael D.;
Laschke, Matthias W.;
Cucchiarini, Magali

Publication type:

Article

Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair.

Published in:

BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/1215263

By:

Rey-Rico, Ana;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

Early loss of subchondral bone following microfracture is counteracted by bone marrow aspirate in a translational model of osteochondral repair.

Published in:

Scientific Reports, 2017, p. 45189, doi. 10.1038/srep45189

By:

Gao, Liang;
Orth, Patrick;
Müller-Brandt, Kathrin;
Goebel, Lars K. H.;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

A novel algorithm for a precise analysis of subchondral bone alterations.

Published in:

Scientific Reports, 2016, p. 32982, doi. 10.1038/srep32982

By:

Gao, Liang;
Orth, Patrick;
Goebel, Lars K. H.;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Biomedical-grade, high mannuronic acid content (BioMVM) alginate enhances the proteoglycan production of primary human meniscal fibrochondrocytes in a 3-D microenvironment.

Published in:

Scientific Reports, 2016, p. 28170, doi. 10.1038/srep28170

By:

Rey-Rico, Ana;
Klich, Angelique;
Cucchiarini, Magali;
Madry, Henning

Publication type:

Article

Application of Nanotechnology for Sensitive Detection of Low-Abundance Single-Nucleotide Variations in Genomic DNA: A Review.

Published in:

Nanomaterials (2079-4991), 2021, v. 11, n. 6, p. 1384, doi. 10.3390/nano11061384

By:

Mukhtar, Mahwash;
Sargazi, Saman;
Barani, Mahmood;
Madry, Henning;
Rahdar, Abbas;
Cucchiarini, Magali

Publication type:

Article

Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections.

Published in:

Nanomaterials (2079-4991), 2021, v. 11, n. 2, p. 546, doi. 10.3390/nano11020546

By:

Qindeel, Maimoona;
Barani, Mahmood;
Rahdar, Abbas;
Arshad, Rabia;
Cucchiarini, Magali;
Zille, Andrea

Publication type:

Article

Cyclodextrin Cationic Polymer-Based Nanoassemblies to Manage Inflammation by Intra-Articular Delivery Strategies.

Published in:

Nanomaterials (2079-4991), 2020, v. 10, n. 9, p. 1712, doi. 10.3390/nano10091712

By:

Cordaro, Annalaura;
Zagami, Roberto;
Malanga, Milo;
Venkatesan, Jagadeesh Kumar;
Alvarez-Lorenzo, Carmen;
Cucchiarini, Magali;
Piperno, Anna;
Mazzaglia, Antonino

Publication type:

Article

Therapeutic Delivery of rAAV sox9 via Polymeric Micelles Counteracts the Effects of Osteoarthritis-Associated Inflammatory Cytokines in Human Articular Chondrocytes.

Published in:

Nanomaterials (2079-4991), 2020, v. 10, n. 6, p. 1238, doi. 10.3390/nano10061238

By:

Urich, Jonas;
Cucchiarini, Magali;
Rey-Rico, Ana

Publication type:

Article

rAAV-Mediated Overexpression of SOX9 and TGF-β via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells.

Published in:

Nanomaterials (2079-4991), 2020, v. 10, n. 5, p. 855, doi. 10.3390/nano10050855

By:

Meng, Weikun;
Rey-Rico, Ana;
Claudel, Mickaël;
Schmitt, Gertrud;
Speicher-Mentges, Susanne;
Pons, Françoise;
Lebeau, Luc;
Venkatesan, Jagadeesh K.;
Cucchiarini, Magali

Publication type:

Article

Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer.

Published in:

Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 8b, p. 2476, doi. 10.1111/j.1582-4934.2008.00474.x

By:

Cucchiarini, Magali;
Terwilliger, Ernest F.;
Kohn, Dieter;
Madry, Henning

Publication type:

Article

rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ.

Published in:

Journal of Translational Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1479-5876-11-211

By:

Venkatesan, Jagadeesh K.;
Rey-Rico, Ana;
Schmitt, Gertrud;
Wezel, Anna;
Madry, Henning;
Cucchiarini, Magali

Publication type:

Article

rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ.

Published in:

2013

By:

Venkatesan, Jagadeesh K;
Rey-Rico, Ana;
Schmitt, Gertrud;
Wezel, Anna;
Madry, Henning;
Cucchiarini, Magali

Publication type:

journal article

Cells, soluble factors and matrix harmonically play the concert of allograft integration.

Published in:

2019

By:

de Girolamo, Laura;
Ragni, Enrico;
Cucchiarini, Magali;
van Bergen, Christian J. A.;
Hunziker, Ernst B.;
Chubinskaya, Susanna

Publication type:

journal article

Asymptomatic focal calcium pyrophosphate crystal deposition within partially failed repair tissue after matrix-assisted autologous chondrocyte implantation.

Published in:

2019

By:

Gao, Liang;
Oláh, Tamás;
Cucchiarini, Magali;
Madry, Henning

Publication type:

journal article