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Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates.
- Published in:
- Science Translational Medicine, 2024, v. 16, n. 741, p. 1, doi. 10.1126/scitranslmed.adl2055
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- Article
The Therapeutic Monoclonal Antibody Bamlanivimab Does Not Enhance SARS-CoV-2 Infection by FcR-Mediated Mechanisms.
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- Pathogens, 2023, v. 12, n. 12, p. 1408, doi. 10.3390/pathogens12121408
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- Article
Modelling Marburg Virus Disease in Syrian Golden Hamsters: Contrasted Virulence Between Angola and Ci67 Strains.
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- Journal of Infectious Diseases, 2023, v. 228, p. S559, doi. 10.1093/infdis/jiad361
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- Article
Natural History of Nonhuman Primates After Oral Exposure to Ebola Virus Variant Makona.
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- Journal of Infectious Diseases, 2023, v. 228, p. S571, doi. 10.1093/infdis/jiad225
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- Article
The Mucin-Like Domain of the Ebola Glycoprotein Does Not Impact Virulence or Pathogenicity in Ferrets.
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- Journal of Infectious Diseases, 2023, v. 228, p. S587, doi. 10.1093/infdis/jiad240
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- Article
Pathogenesis of Aerosolized Ebola Virus Variant Makona in Nonhuman Primates.
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- Journal of Infectious Diseases, 2023, v. 228, p. S604, doi. 10.1093/infdis/jiad137
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- Article
A Highly Attenuated Panfilovirus VesiculoVax Vaccine Rapidly Protects Nonhuman Primates Against Marburg Virus and 3 Species of Ebola Virus.
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- Journal of Infectious Diseases, 2023, v. 228, p. S660, doi. 10.1093/infdis/jiad157
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- Article
Long-term Prophylaxis Against Aerosolized Marburg Virus in Nonhuman Primates With an Afucosylated Monoclonal Antibody.
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- Journal of Infectious Diseases, 2023, v. 228, p. S701, doi. 10.1093/infdis/jiad278
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- Article
A Recombinant Vesicular Stomatitis Virus–Based Vaccine Provides Postexposure Protection Against Bundibugyo Ebolavirus Infection.
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- Journal of Infectious Diseases, 2023, v. 228, p. S712, doi. 10.1093/infdis/jiad207
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- Article
The Arenaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens.
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- Journal of Infectious Diseases, 2023, v. 228, p. S359, doi. 10.1093/infdis/jiac266
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- Article
A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses.
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- Viruses (1999-4915), 2023, v. 15, n. 5, p. 1077, doi. 10.3390/v15051077
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- Article
Natural history of nonhuman primates after conjunctival exposure to Ebola virus.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-31027-7
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- Article
A single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates.
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- Science Translational Medicine, 2022, v. 14, n. 675, p. 1, doi. 10.1126/scitranslmed.abq6364
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- Article
An introduction to the Marburg virus vaccine consortium, MARVAC.
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- PLoS Pathogens, 2022, v. 18, n. 10, p. 1, doi. 10.1371/journal.ppat.1010805
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- Article
Nonhuman Primates Are Protected against Marburg Virus Disease by Vaccination with a Vesicular Stomatitis Virus Vector-Based Vaccine Prepared under Conditions to Allow Advancement to Human Clinical Trials.
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- Vaccines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/vaccines10101582
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- Article
Reversion of Ebolavirus Disease from a Single Intramuscular Injection of a Pan-Ebolavirus Immunotherapeutic.
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- Pathogens, 2022, v. 11, n. 6, p. 655, doi. 10.3390/pathogens11060655
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- Article
A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge.
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- PLoS Neglected Tropical Diseases, 2022, v. 16, n. 5, p. 1, doi. 10.1371/journal.pntd.0010433
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- Article
Development of a SARS-CoV-2 Vaccine Candidate Using Plant-Based Manufacturing and a Tobacco Mosaic Virus-Like Nano-Particle.
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- Vaccines, 2021, v. 9, n. 11, p. 1347, doi. 10.3390/vaccines9111347
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- Article
Recombinant Protein Filovirus Vaccines Protect Cynomolgus Macaques From Ebola, Sudan, and Marburg Viruses.
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- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.703986
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- Article
Single dose rVSVΔG-JUNVGP vaccine protects guinea pigs against lethal Junin virus challenge.
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- NPJ Vaccines, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41541-021-00361-0
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- Article
Ebola vaccine–induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects.
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- Science Translational Medicine, 2021, v. 13, n. 602, p. 1, doi. 10.1126/scitranslmed.abg6128
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- Article
Combination therapy protects macaques against advanced Marburg virus disease.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22132-0
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- Article
A single dose investigational subunit vaccine for human use against Nipah virus and Hendra virus.
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- NPJ Vaccines, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41541-021-00284-w
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- Article
Endotheliopathy and Platelet Dysfunction as Hallmarks of Fatal Lassa Fever.
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- 2020
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- journal article
Antibodies from Sierra Leonean and Nigerian Lassa fever survivors cross-react with recombinant proteins representing Lassa viruses of divergent lineages.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72539-w
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- Article
Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase.
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- Virology Journal, 2020, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12985-020-01396-w
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- Article
Crimean-Congo hemorrhagic fever virus strains Hoti and Afghanistan cause viremia and mild clinical disease in cynomolgus monkeys.
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- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 8, p. 1, doi. 10.1371/journal.pntd.0008637
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- Article
Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17446-4
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- Article
An Intranasal Exposure Model of Lethal Nipah Virus Infection in African Green Monkeys.
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- 2020
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- journal article
Resistance of Cynomolgus Monkeys to Nipah and Hendra Virus Disease Is Associated With Cell-Mediated and Humoral Immunity.
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- 2020
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- journal article
A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection.
- Published in:
- 2020
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- journal article
Rational design of universal immunotherapy for TfR1-tropic arenaviruses.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13924-6
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- Article
Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death.
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- 2020
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- journal article
Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death.
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- Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 539, doi. 10.1172/JCI131958
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- Article
Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-53037-0
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- Article
Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo).
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- 2018
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- journal article
Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans.
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- 2018
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- journal article
Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates.
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- 2018
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- journal article
Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates.
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- 2018
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- journal article
siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease.
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- 2017
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- journal article
Transcriptome Analysis of Circulating Immune Cell Subsets Highlight the Role of Monocytes in Zaire Ebola Virus Makona Pathogenesis.
- Published in:
- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01372
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- Article
Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants.
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- Scientific Reports, 2017, v. 7, n. 1, p. N.PAG, doi. 10.1038/s41598-017-09963-y
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- Article
Field Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection.
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- Journal of Infectious Diseases, 2016, v. 214, p. S203, doi. 10.1093/infdis/jiw261
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- Article
Analytical Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection.
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- Journal of Infectious Diseases, 2016, v. 214, p. S210, doi. 10.1093/infdis/jiw293
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- Article
The Domestic Ferret (Mustela putorius furo) as a Lethal Infection Model for 3 Species of Ebolavirus.
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- 2016
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- journal article
Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy.
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- Scientific Reports, 2016, p. 30916, doi. 10.1038/srep30916
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- Article
Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits.
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- Nature Communications, 2016, v. 7, n. 5, p. 11544, doi. 10.1038/ncomms11544
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Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model.
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- 2015
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- journal article
The immunomodulating V and W proteins of Nipah virus determine disease course.
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- Nature Communications, 2015, v. 6, n. 6, p. 7483, doi. 10.1038/ncomms8483
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- Article
Old World Hantaviruses in Rodents in New Orleans, Louisiana.
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- American Journal of Tropical Medicine & Hygiene, 2014, v. 90, n. 5, p. 897, doi. 10.4269/ajtmh.13-0683
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- Article