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Mutations of the transcription factor AML1/CBFA2 are uncommon in blastic transformation of chronic myeloid leukaemia.
Published in:
2001
By:
- Steer, E J;
- Goldman, J M;
- Cross, N C P;
- Cross, N C
Publication type:
Letter
Detection and quantification of residual disease in chronic myelogenous leukemia.
Published in:
Leukemia (08876924), 2000, v. 14, n. 6, p. 998, doi. 10.1038/sj.leu.2401811
By:
- Hochhaus, A;
- Weisser, A;
- Rosée, P La;
- Emig, M;
- Müller, M C;
- Saußele, S;
- Reiter, A;
- Kuhn, C;
- Berger, U;
- Hehlmann, R;
- Cross, N C P
Publication type:
Article
Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR.
Published in:
1999
By:
- Emig, M;
- Saußele, S;
- Wittor, H;
- Weißer, A;
- Reiter, A;
- Willer, A;
- Berger, U;
- Hehlmann, R;
- Cross, N C P;
- Hochhaus, A;
- Saussele, S;
- Weisser, A;
- Cross, N C
Publication type:
journal article
Rarity of dominant-negative mutations of the G-CSF receptor in patients with blast crisis of chronic myeloid leukemia or de novo acute leukemia.
Published in:
1997
By:
- Carapeti, M;
- Soede-Bobok, A;
- Hochhaus, A;
- Sill, H;
- Touw, I P;
- Goldman, J M;
- Cross, N C P;
- Cross, N C
Publication type:
journal article
An extremely delayed cytogenetic response to interferon-α in a patient with chronic myeloid leukaemia.
Published in:
Leukemia (08876924), 1997, v. 11, n. 4, p. 614, doi. 10.1038/sj.leu.2400622
By:
- Whiteway, A J;
- Reid, C D L;
- Cross, N C P
Publication type:
Article
The commonly deleted region at 9p21-22 in lymphoblastic leukemias spans at least 400 kb and includes p16 but not p15 or the IFN gene cluster.
Published in:
1997
By:
- Aguiar, R C T;
- Sill, H;
- Goldman, J M;
- Cross, N C P;
- Aguiar, R C;
- Cross, N C
Publication type:
journal article
Cloning of ZNF237, a novel member of the MYM gene family that maps to human chromosome 13q11→q12.
Published in:
Cytogenetics & Cell Genetics, 2000, v. 89, n. 1/2, p. 24, doi. 10.1159/000015584
By:
- Sohal, J.;
- Reiter, A.;
- Goldman, J. M.;
- Cross, N. C. P.
Publication type:
Article
Assignment of ZNF262 to human chromosome band 1p34→p32 by in situ hybridization.
Published in:
Cytogenetics & Cell Genetics, 1999, v. 85, n. 3/4, p. 306, doi. 10.1159/000015282
By:
- Sohal, J.;
- Chase, A.;
- Goldman, J. M.;
- Cross, N. C. P.
Publication type:
Article
Clinical evidence for a graft-versus-tumour effect following allogeneic HSCT for t(8;13) atypical myeloproliferative disorder.
Published in:
Bone Marrow Transplantation, 2009, v. 44, n. 3, p. 197, doi. 10.1038/bmt.2008.448
By:
- Townsend, W.;
- Cross, N. C. P.;
- Waghorn, K.;
- Somana, K.;
- Ramsay, A.;
- Thomson, K.;
- Peggs, K.
Publication type:
Article
Detection of leukemia-associated mutations in peripheral blood DNA of hematologically normal elderly individuals.
Published in:
Leukemia (08876924), 2015, v. 29, n. 7, p. 1600, doi. 10.1038/leu.2015.13
By:
- Score, J;
- Chase, A;
- Forsberg, L A;
- Feng, L;
- Waghorn, K;
- Jones, A V;
- Rasi, C;
- Linch, D C;
- Dumanski, J P;
- Gale, R E;
- Cross, N C P
Publication type:
Article
Response to Ho-Wan Ip and Chi-Chiu.
Published in:
2015
By:
- Cross, N C P;
- Müller, M C;
- Hochhaus, A
Publication type:
commentary
KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1223, doi. 10.1038/leu.2015.24
By:
- Arock, M;
- Sotlar, K;
- Akin, C;
- Broesby-Olsen, S;
- Hoermann, G;
- Escribano, L;
- Kristensen, T K;
- Kluin-Nelemans, H C;
- Hermine, O;
- Dubreuil, P;
- Sperr, W R;
- Hartmann, K;
- Gotlib, J;
- Cross, N C P;
- Haferlach, T;
- Garcia-Montero, A;
- Orfao, A;
- Schwaab, J;
- Triggiani, M;
- Horny, H-P
Publication type:
Article
Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 5, p. 999, doi. 10.1038/leu.2015.29
By:
- Cross, N C P;
- White, H E;
- Colomer, D;
- Ehrencrona, H;
- Foroni, L;
- Gottardi, E;
- Lange, T;
- Lion, T;
- Machova Polakova, K;
- Dulucq, S;
- Martinelli, G;
- Oppliger Leibundgut, E;
- Pallisgaard, N;
- Barbany, G;
- Sacha, T;
- Talmaci, R;
- Izzo, B;
- Saglio, G;
- Pane, F;
- Müller, M C
Publication type:
Article
Molecular profiling of myeloid progenitor cells in multi-mutated advanced systemic mastocytosis identifies KIT D816V as a distinct and late event.
Published in:
Leukemia (08876924), 2015, v. 29, n. 5, p. 1115, doi. 10.1038/leu.2015.4
By:
- Jawhar, M;
- Schwaab, J;
- Schnittger, S;
- Sotlar, K;
- Horny, H-P;
- Metzgeroth, G;
- Müller, N;
- Schneider, S;
- Naumann, N;
- Walz, C;
- Haferlach, T;
- Valent, P;
- Hofmann, W-K;
- Cross, N C P;
- Fabarius, A;
- Reiter, A
Publication type:
Article
Bioinformatic analyses of CALR mutations in myeloproliferative neoplasms support a role in signaling.
Published in:
Leukemia (08876924), 2014, v. 28, n. 10, p. 2106, doi. 10.1038/leu.2014.190
By:
- Eder-Azanza, L;
- Navarro, D;
- Aranaz, P;
- Novo, F J;
- Cross, N C P;
- Vizmanos, J L
Publication type:
Article
A multi-centre phase 2 study of azacitidine in chronic myelomonocytic leukaemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 7, p. 1570, doi. 10.1038/leu.2014.85
By:
- Drummond, M W;
- Pocock, C;
- Boissinot, M;
- Mills, J;
- Brown, J;
- Cauchy, P;
- Cross, N C P;
- Hartley, S;
- Kell, J;
- Szubert, A;
- Cockerill, P N;
- Bowen, D T
Publication type:
Article
Granulocyte colony-stimulating factor receptor T595I (T618I) mutation confers ligand independence and enhanced signaling.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2407, doi. 10.1038/leu.2013.164
By:
- Mehta, H M;
- Glaubach, T;
- Long, A;
- Lu, H;
- Przychodzen, B;
- Makishima, H;
- McDevitt, M A;
- Cross, N C P;
- Maciejewski, J;
- Corey, S J
Publication type:
Article
Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase.
Published in:
Leukemia (08876924), 2013, v. 27, n. 11, p. 2254, doi. 10.1038/leu.2013.129
By:
- Metzgeroth, G;
- Schwaab, J;
- Gosenca, D;
- Fabarius, A;
- Haferlach, C;
- Hochhaus, A;
- Cross, N C P;
- Hofmann, W-K;
- Reiter, A
Publication type:
Article
Distribution of genomic breakpoints in chronic myeloid leukemia: analysis of 308 patients.
Published in:
Leukemia (08876924), 2013, v. 27, n. 10, p. 2105, doi. 10.1038/leu.2013.116
By:
- Ross, D M;
- O'Hely, M;
- Bartley, P A;
- Dang, P;
- Score, J;
- Goyne, J M;
- Sobrinho-Simoes, M;
- Cross, N C P;
- Melo, J V;
- Speed, T P;
- Hughes, T P;
- Morley, A A
Publication type:
Article
Why do we see JAK2 exon 12 mutations in myeloproliferative neoplasms?
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1930, doi. 10.1038/leu.2013.85
By:
- Vorechovsky, I;
- Jones, A V;
- Cross, N C P
Publication type:
Article
JAK2V617F allele burden, JAK2 46/1 haplotype and clinical features of Chinese with myeloproliferative neoplasms.
Published in:
Leukemia (08876924), 2013, v. 27, n. 8, p. 1763, doi. 10.1038/leu.2013.21
By:
- Wang, J;
- Xu, Z;
- Liu, L;
- Gale, R P;
- Cross, N C P;
- Jones, A V;
- Qin, T;
- Ai, X;
- Xu, J;
- Zhang, T;
- Sun, X;
- Li, Q;
- Zhang, P;
- Zhang, Y;
- Xiao, Z
Publication type:
Article
Standardized definitions of molecular response in chronic myeloid leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 10, p. 2172, doi. 10.1038/leu.2012.104
By:
- Cross, N C P;
- White, H E;
- Müller, M C;
- Saglio, G;
- Hochhaus, A
Publication type:
Article
Limited clinical activity of nilotinib and sorafenib in FIP1L1-PDGFRA positive chronic eosinophilic leukemia with imatinib-resistant T674I mutation.
Published in:
2012
By:
- Metzgeroth, G;
- Erben, P;
- Martin, H;
- Mousset, S;
- Teichmann, M;
- Walz, C;
- Klippstein, T;
- Hochhaus, A;
- Cross, N C P;
- Hofmann, W-K;
- Reiter, A
Publication type:
Letter
The t(4;9)(q11;q33) fuses CEP110 to KIT in a case of acute myeloid leukemia.
Published in:
Leukemia (08876924), 2011, v. 25, n. 6, p. 1049, doi. 10.1038/leu.2011.40
By:
- Grand, F. H.;
- Waghorn, K.;
- Ernst, T.;
- Ohyashiki, K.;
- Cross, N. C. P.
Publication type:
Article
Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance.
Published in:
2011
By:
- Grossmann, V.;
- Kohlmann, A.;
- Eder, C.;
- Haferlach, C.;
- Kern, W.;
- Cross, N. C. P.;
- Haferlach, T.;
- Schnittger, S.
Publication type:
Letter
IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis.
Published in:
2011
By:
- Soverini, S.;
- Score, J.;
- Iacobucci, I.;
- Poerio, A.;
- Lonetti, A.;
- Gnani, A.;
- Colarossi, S.;
- Ferrari, A.;
- Castagnetti, F.;
- Rosti, G.;
- Cervantes, F.;
- Hochhaus, A.;
- Delledonne, M.;
- Ferrarini, A.;
- Sazzini, M.;
- Luiselli, D.;
- Baccarani, M.;
- Cross, N. C. P.;
- Martinelli, G.
Publication type:
Case Study
Analysis of genomic breakpoints in p190 and p210 BCR-ABL indicate distinct mechanisms of formation.
Published in:
2010
By:
- Score, J.;
- Calasanz, M. J.;
- Ottman, O.;
- Pane, F.;
- Yeh, R. F.;
- Sobrinho-Simões, M. A.;
- Kreil, S.;
- Ward, D.;
- Hidalgo-Curtis, C.;
- Melo, J. V.;
- Wiemels, J.;
- Nadel, B.;
- Cross, N. C. P.;
- Grand, F. H.;
- Sobrinho-Simões, M A
Publication type:
journal article
Harmonization of molecular monitoring of CML therapy in Europe.
Published in:
Leukemia (08876924), 2009, v. 23, n. 11, p. 1957, doi. 10.1038/leu.2009.168
By:
- Müller, M. C.;
- Cross, N. C. P.;
- Erben, P.;
- Schenk, T.;
- Hanfstein, B.;
- Ernst, T.;
- Hehlmann, R.;
- Branford, S.;
- Saglio, G.;
- Hochhaus, A.
Publication type:
Article
Imatinib sensitivity as a consequence of a CSF1R-Y571D mutation and CSF1/CSF1R signaling abnormalities in the cell line GDM1.
Published in:
Leukemia (08876924), 2009, v. 23, n. 2, p. 358, doi. 10.1038/leu.2008.295
By:
- Chase, A.;
- Schultheis, B.;
- Kreil, S.;
- Baxter, J.;
- Hidalgo-Curtis, C.;
- Jones, A.;
- Zhang, L.;
- Grand, F. H.;
- Melo, J. V.;
- Cross, N. C. P.
Publication type:
Article
Detection and molecular monitoring of FIP1L1-PDGFRA-positive disease by analysis of patient-specific genomic DNA fusion junctions.
Published in:
2009
By:
- Score, J.;
- Walz, C.;
- Jovanovic, J. V.;
- Jones, A. V.;
- Waghorn, K.;
- Hidalgo-Curtis, C.;
- Lin, F.;
- Grimwade, D.;
- Grand, F.;
- Reiter, A.;
- Cross, N. C. P.
Publication type:
journal article
The molecular anatomy of the FIP1L1-PDGFRA fusion gene.
Published in:
2009
By:
- Walz, C.;
- Score, J.;
- Mix, J.;
- Cilloni, D.;
- Roche-Lestienne, C.;
- Yeh, R.-F.;
- Wiemels, J. L.;
- Ottaviani, E.;
- Erben, P.;
- Hochhaus, A.;
- Baccarani, M.;
- Grimwade, D.;
- Preudhomme, C.;
- Apperley, J.;
- Martinelli, G.;
- Saglio, G.;
- Cross, N. C. P.;
- Reiter, A.;
- European LeukemiaNet
Publication type:
journal article
Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disorders.
Published in:
Leukemia (08876924), 2008, v. 22, p. P74
By:
- Walz, C.;
- Cross, N. C. P.;
- Van Etten, R. A.;
- Reiter, A.
Publication type:
Article
BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features.
Published in:
2008
By:
- Cross, N. C. P.;
- Daley, G. Q.;
- Green, A. R.;
- Hughes, T. P.;
- Jamieson, C.;
- Manley, P.;
- Mughal, T.;
- Perrotti, D.;
- Radich, J.;
- Skoda, R.;
- Soverini, S.;
- Vainchenker, W.;
- Verstovsek, S.;
- Villeval, J.-L.;
- Goldman, J. M.
Publication type:
Editorial
Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disorders.
Published in:
2008
By:
- Walz, C;
- Cross, N C P;
- Van Etten, R A;
- Reiter, A
Publication type:
journal article
JAK2 Mutations are present in all cases of polycythemia vera.
Published in:
2008
By:
- Wang, Y. L.;
- Vandris, K.;
- Jones, A.;
- Cross, N. C. P.;
- Christos, P.;
- Adriano, F.;
- Silver, R. T.
Publication type:
Letter
No evidence for amplification of V617F JAK2 in myeloproliferative disorders.
Published in:
2007
By:
- Jones, A. V.;
- Bunyan, D. J.;
- Cross, N. C. P.
Publication type:
Letter
The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus.
Published in:
2007
By:
- Burgstaller, S.;
- Kreil, S.;
- Waghorn, K.;
- Metzgeroth, G.;
- Preudhomme, C.;
- Zoi, K.;
- White, H.;
- Cilloni, D.;
- Zoi, C.;
- Brito-Babapulle, F.;
- Walz, C.;
- Reiter, A.;
- Cross, N. C. P.
Publication type:
journal article
A novel ETV6-PDGFRB fusion transcript missed by standard screening in a patient with an imatinib responsive chronic myeloproliferative disease.
Published in:
2007
By:
- Curtis, C. E.;
- Grand, F. H.;
- Waghorn, K.;
- Sahoo, T. P.;
- George, J.;
- Cross, N. C. P.
Publication type:
Letter
Chronic myeloid leukemia – some topical issues.
Published in:
2007
By:
- Mughal, T;
- Cortes, J;
- Cross, N C P;
- Donato, N;
- Hantschel, O;
- Jabbour, E;
- Kantarjian, H;
- Melo, J V;
- Skorski, T;
- Silver, R T;
- Goldman, J M
Publication type:
Editorial
FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells.
Published in:
2007
By:
- Crescenzi, B.;
- Chase, A.;
- La Starza, R.;
- Beacci, D.;
- Rosti, V.;
- Gallì, A.;
- Specchia, G.;
- Martelli, M. F.;
- Vandenberghe, P.;
- Cools, J.;
- Jones, A. V.;
- Cross, N. C. P.;
- Marynen, P.;
- Mecucci, C.;
- Starza, R La;
- Gallì, A
Publication type:
journal article
JAK2V617F mutational frequency in polycythemia vera: 100%, >90%, less?
Published in:
2006
By:
- Verstovsek, S.;
- Silver, R. T.;
- Cross, N. C. P.;
- Tefferi, A.
Publication type:
Letter
Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia.
Published in:
Leukemia (08876924), 2006, v. 20, n. 11, p. 1925, doi. 10.1038/sj.leu.2404388
By:
- Branford, S.;
- Cross, N. C. P.;
- Hochhaus, A.;
- Radich, J.;
- Saglio, G.;
- Kaeda, J.;
- Goldman, J.;
- Hughes, T.
Publication type:
Article
Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma.
Published in:
Leukemia (08876924), 2006, v. 20, n. 9, p. 1610, doi. 10.1038/sj.leu.2404304
By:
- Chiecchio, L.;
- Protheroe, R. K. M.;
- Ibrahim, A. H.;
- Cheung, K. L.;
- Rudduck, C.;
- Dagrada, G. P.;
- Cabanas, E. D.;
- Parker, T.;
- Nightingale, M.;
- Wechalekar, A.;
- Orchard, K. H.;
- Harrison, C. J.;
- Cross, N. C. P.;
- Morgan, G. J.;
- Ross, F. M.
Publication type:
Article
Identification of a novel imatinib responsive KIF5B-PDGFRA fusion gene following screening for PDGFRA overexpression in patients with hypereosinophilia.
Published in:
Leukemia (08876924), 2006, v. 20, n. 5, p. 827, doi. 10.1038/sj.leu.2404154
By:
- Score, J.;
- Curtis, C.;
- Waghorn, K.;
- Stalder, M.;
- Jotterand, M.;
- Grand, F. H.;
- Cross, N. C. P.
Publication type:
Article
JAK2 V617F mutation in classic chronic myeloproliferative diseases: a report on a series of 349 patients.
Published in:
Leukemia (08876924), 2006, v. 20, n. 3, p. 534, doi. 10.1038/sj.leu.2404086
By:
- Vizmanos, J. L.;
- Ormazábal, C.;
- Larráyoz, M. J.;
- Cross, N. C. P.;
- Calasanz, M. J.
Publication type:
Article
Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma.
Published in:
Leukemia (08876924), 2005, v. 19, n. 9, p. 1634, doi. 10.1038/sj.leu.2403857
By:
- Ross, F. M.;
- Ibrahim, A. H.;
- Vilain-Holmes, A.;
- Winfield, M. O.;
- Chiecchio, L.;
- Protheroe, R. K. M.;
- Strike, P.;
- Gunasekera, J. L.;
- Jones, A.;
- Harrison, C. J.;
- Morgan, G. J.;
- Cross, N. C. P.
Publication type:
Article
Broad molecular screening of an unclassifiable myeloproliferative disorder reveals an unexpected ETV6/ABL1 fusion transcript.
Published in:
2005
By:
- Meyer-Monard, S;
- Mühlematter, D;
- Streit, A;
- Chase, A J;
- Gratwohl, A;
- Cross, N C P;
- Jotterand, M;
- Tichelli, A
Publication type:
Letter
The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1.
Published in:
Leukemia (08876924), 2005, v. 19, n. 6, p. 1005, doi. 10.1038/sj.leu.2403712
By:
- Walz, C.;
- Chase, A.;
- Schoch, C.;
- Weisser, A.;
- Schlegel, F.;
- Hochhaus, A.;
- Fuchs, R.;
- Schmitt-Gräff, A.;
- Hehlmann, R.;
- Cross, N. C. P.;
- Reiter, A.
Publication type:
Article
Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies.
Published in:
Leukemia (08876924), 2005, v. 19, n. 2, p. 245, doi. 10.1038/sj.leu.2403605
By:
- Odero, M. D.;
- Grand, F. H.;
- Iqbal, S.;
- Ross, F.;
- Roman, J. P.;
- Vizmanos, J. L.;
- Andrieux, J.;
- Laïef;, J. L.;
- Calasanz, M. J.;
- Cross, N. C. P.
Publication type:
Article
Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074.
Published in:
Leukemia (08876924), 2004, v. 18, n. 5, p. 962, doi. 10.1038/sj.leu.2403347
By:
- Grand, E. K.;
- Chase, A. J.;
- Heath, C.;
- Rahemtulla, A.;
- Cross, N. C. P.
Publication type:
Article

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