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Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation.
- Published in:
- PLoS Genetics, 2020, v. 16, n. 1, p. 1, doi. 10.1371/journal.pgen.1008537
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- Publication type:
- Article
Single cell profiling at the maternal–fetal interface reveals a deficiency of PD-L1<sup>+</sup> non-immune cells in human spontaneous preterm labor.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35051-5
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- Publication type:
- Article
Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 20, p. 11684, doi. 10.1093/nar/gkx773
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- Publication type:
- Article
Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus.
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- Nucleic Acids Research, 2016, v. 44, n. 7, p. 3082, doi. 10.1093/nar/gkv1358
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- Publication type:
- Article
Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection.
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- Nucleic Acids Research, 2014, v. 42, n. 19, p. 11865
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- Publication type:
- Article
DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2.
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- Nucleic Acids Research, 2009, v. 37, n. 22, p. 7381, doi. 10.1093/nar/gkp833
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- Publication type:
- Article
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function.
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- Molecular Human Reproduction, 2014, v. 20, n. 12, p. 1198, doi. 10.1093/molehr/gau075
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- Publication type:
- Article
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24243-0
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- Publication type:
- Article
Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer's disease brains.
- Published in:
- Cell & Bioscience, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13578-023-01120-5
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- Publication type:
- Article
CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.
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- Nature Biotechnology, 2017, v. 35, n. 6, p. 561, doi. 10.1038/nbt.3853
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- Publication type:
- Article
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.
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- Nature Biotechnology, 2015, v. 33, n. 5, p. 510, doi. 10.1038/nbt.3199
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- Publication type:
- Article
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome.
- Published in:
- Nature Genetics, 2007, v. 39, n. 3, p. 311, doi. 10.1038/ng1966
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- Publication type:
- Article
RNA-guided gene activation by CRISPR-Cas9-based transcription factors.
- Published in:
- Nature Methods, 2013, v. 10, n. 10, p. 973, doi. 10.1038/nmeth.2600
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- Publication type:
- Article
Synergistic and tunable human gene activation by combinations of synthetic transcription factors.
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- Nature Methods, 2013, v. 10, n. 3, p. 239, doi. 10.1038/nmeth.2361
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- Publication type:
- Article
DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays.
- Published in:
- Nature Methods, 2006, v. 3, n. 7, p. 503, doi. 10.1038/nmeth888
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- Publication type:
- Article
Chromatin Accessibility Mapping Identifies Mediators of Basal Transcription and Retinoid-Induced Repression of OTX2 in Medulloblastoma.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107156
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- Publication type:
- Article
Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation.
- Published in:
- BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-3167-3
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- Publication type:
- Article
Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.
- Published in:
- Environmental Health Perspectives, 2017, v. 125, n. 10, p. 1, doi. 10.1289/EHP1937
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- Publication type:
- Article
Histone modifications at human enhancers reflect global cell-type-specific gene expression.
- Published in:
- Nature, 2009, v. 459, n. 7243, p. 108, doi. 10.1038/nature07829
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- Publication type:
- Article
Single-nucleus multi-omics of Parkinson's disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks.
- Published in:
- Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01803-1
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- Publication type:
- Article
Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits.
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- G3: Genes | Genomes | Genetics, 2019, v. 9, n. 8, p. 2521, doi. 10.1534/g3.119.400294
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- Publication type:
- Article
HDAC inhibitors cause site-specific chromatin remodeling at PU.1-bound enhancers in K562 cells.
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- Epigenetics & Chromatin, 2016, p. 1, doi. 10.1186/s13072-016-0065-5
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- Publication type:
- Article
DNA methylation and differentiation: HOX genes in muscle cells.
- Published in:
- Epigenetics & Chromatin, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8935-6-25
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- Publication type:
- Article
A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter.
- Published in:
- Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 4, p. 680, doi. 10.1111/j.1582-4934.2008.00621.x
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- Publication type:
- Article
Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.
- Published in:
- Genome Biology, 2012, v. 13, n. 10, p. 1, doi. 10.1186/gb-2012-13-10-R88
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- Publication type:
- Article
Dissecting the regulatory architecture of gene expression QTLs.
- Published in:
- Genome Biology, 2012, v. 13, n. 1, p. 1, doi. 10.1186/gb-2012-13-1-r7
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- Publication type:
- Article
Evaluating Chromatin Accessibility Differences Across Multiple Primate Species Using a Joint Modeling Approach.
- Published in:
- Genome Biology & Evolution, 2019, v. 11, n. 10, p. 3035, doi. 10.1093/gbe/evz218
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- Publication type:
- Article
Comparative Analyses of Chromatin Landscape in White Adipose Tissue Suggest Humans May Have Less Beigeing Potential than Other Primates.
- Published in:
- Genome Biology & Evolution, 2019, v. 11, n. 7, p. 1997, doi. 10.1093/gbe/evz134
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- Publication type:
- Article
Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee.
- Published in:
- Genome Biology & Evolution, 2018, v. 10, n. 3, p. 826, doi. 10.1093/gbe/evy041
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- Publication type:
- Article
Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
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- Human Molecular Genetics, 2015, v. 24, n. 19, p. 5433, doi. 10.1093/hmg/ddv267
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- Publication type:
- Article
Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.
- Published in:
- Mammalian Genome, 2018, v. 29, n. 1/2, p. 153, doi. 10.1007/s00335-018-9739-6
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- Publication type:
- Article
DNase?I sensitivity QTLs are a major determinant of human expression variation.
- Published in:
- Nature, 2012, v. 482, n. 7385, p. 390, doi. 10.1038/nature10808
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- Publication type:
- Article
333. Preferential Targeting of Transcriptional Start Sites after Retroviral-Mediated T-Cell Gene Therapy for Adenosine Deaminase Deficiency
- Published in:
- 2005
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- Publication type:
- Abstract
Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum.
- Published in:
- Nature Neuroscience, 2015, v. 18, n. 5, p. 647, doi. 10.1038/nn.3995
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- Publication type:
- Article
Interactions between β2-syntrophin and a family of microtubule-associated serine/threonine kinases.
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- Nature Neuroscience, 1999, v. 2, n. 7, p. 611, doi. 10.1038/10165
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- Publication type:
- Article
Correction: Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association.
- Published in:
- 2015
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- Publication type:
- Correction Notice
Interactions of Chromatin Context, Binding Site Sequence Content, and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation.
- Published in:
- PLoS Genetics, 2015, v. 11, n. 1, p. 1, doi. 10.1371/journal.pgen.1004885
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- Publication type:
- Article
Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association.
- Published in:
- PLoS Genetics, 2014, v. 10, n. 11, p. 1, doi. 10.1371/journal.pgen.1004798
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- Publication type:
- Article
Deletion of a Conserved <i>cis</i>-Element in the <i>Ifng</i> Locus Highlights the Role of Acute Histone Acetylation in Modulating Inducible Gene Transcription.
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- PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1003969
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- Publication type:
- Article
Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes.
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- PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002871
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- Publication type:
- Article
Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection.
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- PLoS Genetics, 2012, v. 8, n. 6, p. 1, doi. 10.1371/journal.pgen.1002789
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- Publication type:
- Article
CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression.
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- PLoS Genetics, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.pgen.1001023
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- Publication type:
- Article
Identification and Characterization of Cell Type-Specific and Ubiquitous Chromatin Regulatory Structures in the Human Genome.
- Published in:
- PLoS Genetics, 2007, v. 3, n. 8, p. 1377, doi. 10.1371/journal.pgen.0030136
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- Publication type:
- Article
Genome-Wide Analysis of Menin Binding<br /> Provides Insights into MEN1 Tumorigenesis.
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- PLoS Genetics, 2006, v. 2, n. 4, p. e51, doi. 10.1371/journal.pgen.0020051
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- Publication type:
- Article
Allele-specific and heritable chromatin signatures in humans.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. R2, p. R204, doi. 10.1093/hmg/ddq404
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- Publication type:
- Article
Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs.
- Published in:
- Human Molecular Genetics, 2006, v. 15, n. 13, p. 2098, doi. 10.1093/hmg/ddl133
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- Publication type:
- Article
Suppression of revertant fibersin mdx mice by expression of a functional dystrophin.
- Published in:
- Human Molecular Genetics, 2001, v. 10, n. 24, p. 2745, doi. 10.1093/hmg/10.24.2745
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- Publication type:
- Article
H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites.
- Published in:
- Genome Medicine, 2012, v. 4, n. 5, p. 1, doi. 10.1186/gm346
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- Publication type:
- Article
F-Seq: a feature density estimator for high-throughput sequence tags.
- Published in:
- Bioinformatics, 2008, v. 24, n. 21, p. 2537, doi. 10.1093/bioinformatics/btn480
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- Publication type:
- Article
Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54302-7
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- Publication type:
- Article