Works by Court, Michael H.

Results: 54

Application of eprinomectin‐containing parasiticides at label doses causes neurological toxicosis in cats homozygous for ABCB11930_1931del TC.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 3, p. 226, doi. 10.1111/jvp.13431

By:

Mealey, Katrina L.;
Burke, Neal S.;
Villarino, Nicolas F.;
Court, Michael H.;
Heusser, Jennifer P.

Publication type:

Article

Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug–drug interactions involving canine cytochrome P‐450, UDP‐glucuronosyltransferase, and P‐glycoprotein.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 1, p. 1, doi. 10.1111/jvp.13403

By:

Court, Michael H.;
Mealey, Katrina L.;
Burke, Neal S.;
Jimenez, Tania Perez;
Zhu, Zhaohui;
Wakshlag, Joseph J.

Publication type:

Article

Association of cytochrome P450 2D15 (CYP2D15) nonsynonymous polymorphisms and exon 3 deleted RNA splice variant with CYP2D15 protein content and enzyme function in dog liver microsomes.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 2, p. 77, doi. 10.1111/jvp.13113

By:

Jimenez, Tania Perez;
Zhu, Zhaohui;
Court, Michael H.

Publication type:

Article

Canine orosomucoid (alpha‐1 acid glycoprotein) variants and their influence on drug plasma protein binding.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2021, v. 44, n. 1, p. 116, doi. 10.1111/jvp.12899

By:

Costa, Ana P.;
Court, Michael H.;
Villarino, Nicolas F.;
Burke, Neal S.;
Mealey, Katrina L.

Publication type:

Article

Investigation into the causes of aspirin resistance in healthy dogs.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2019, v. 42, n. 2, p. 160, doi. 10.1111/jvp.12725

By:

Haines, Jillian M.;
Lee, Pamela M.;
Hegedus, Rachel M.;
Hwang, Julianne K.;
Court, Michael H.

Publication type:

Article

High interindividual variability in plasma clopidogrel active metabolite concentrations in healthy cats is associated with sex and cytochrome P450 2C genetic polymorphism.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2019, v. 42, n. 1, p. 16, doi. 10.1111/jvp.12717

By:

Lee, Pamela M.;
Faus, Michele C. L.;
Court, Michael H.

Publication type:

Article

Identification of canine cytochrome P‐450s (CYPs) metabolizing the tramadol (+)‐M1 and (+)‐M2 metabolites to the tramadol (+)‐M5 metabolite in dog liver microsomes.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2018, v. 41, n. 6, p. 815, doi. 10.1111/jvp.12706

By:

Perez Jimenez, Tania E.;
Mealey, Katrina L.;
Schnider, Darren;
Grubb, Tamara L.;
Greene, Stephen A.;
Court, Michael H.

Publication type:

Article

Population variability in animal health: Influence on dose–exposure–response relationships: Part I: Drug metabolism and transporter systems.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2018, v. 41, n. 4, p. E57, doi. 10.1111/jvp.12670

By:

Martinez, Marilyn N.;
Court, Michael H.;
Fink‐Gremmels, Johanna;
Mealey, Katrina L.

Publication type:

Article

Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus.

Published in:

2011

By:

Dostalek, Miroslav;
Court, Michael H.;
Yan, Bingfang;
Akhlaghi, Fatemeh

Publication type:

journal article

Measurement of Muscle Surface Capillary Blood Flow by Laser Doppler Flowmetry.

Published in:

Veterinary Surgery, 1992, v. 21, n. 6, p. 491, doi. 10.1111/j.1532-950X.1992.tb00088.x

By:

NORMAN, WENDY M.;
COURT, MICHAEL H.;
DODMAN, NICHOLAS H.;
PIPERS, FRANK S.

Publication type:

Article

Equine Post-anesthetic Lameness A Retrospective Study.

Published in:

Veterinary Surgery, 1990, v. 19, n. 5, p. 392, doi. 10.1111/j.1532-950X.1990.tb01216.x

By:

RICHEY, MEGHAN T.;
HOLLAND, MELISSA S.;
McGRATH, CHARLES J.;
DODMAN, NICHOLAS H.;
MARSHALL, DURWOOD B.;
COURT, MICHAEL H.;
NORMAN, WENDY M.;
SEELER, DAVID C.

Publication type:

Article

Comparison of Adhesive Polyurethane Membrane and Polypropylene Sutures for Closure of Skin Incisions in Cats.

Published in:

Veterinary Surgery, 1989, v. 18, n. 3, p. 211, doi. 10.1111/j.1532-950X.1989.tb01072.x

By:

COURT, MICHAEL H.;
BELLENGER, CHRISTOPHER R.

Publication type:

Article

Interstitial pH and Pressure in the Dependent Biceps Femoris Muscle of Laterally Recumbent Anesthetized Horses.

Published in:

Veterinary Surgery, 1988, v. 17, n. 4, p. 234, doi. 10.1111/j.1532-950X.1988.tb01003.x

By:

NORMAN, WENDY M.;
DODMAN, NICHOLAS H.;
COURT, MICHAEL H.

Publication type:

Article

Retroversion of the Epiglottis as a Complication of Endotracheal Intubation in the Horse A Pilot Study.

Published in:

Veterinary Surgery, 1986, v. 15, n. 3, p. 275, doi. 10.1111/j.1532-950X.1986.tb00223.x

By:

DODMAN, NICHOLAS H.;
KOBLIK, PHILIP D.;
COURT, MICHAEL H.

Publication type:

Article

Response to Helsby and Tingle.

Published in:

American Journal of Hematology, 2011, v. 86, n. 4, p. 384, doi. 10.1002/ajh.21997

By:

Melanson, Stacy E.F.;
Stevenson, Kristen;
Kim, Haesook;
Antin, Joseph H.;
Court, Michael H.;
Ho, Vincent T.;
Ritz, Jerome;
Soiffer, Robert J.;
Kuo, Frank C.;
Longtine, Janina A.;
Jarolim, Petr

Publication type:

Article

Allelic variations in CYP2B6 and CYP2C19 and survival of patients receiving cyclophosphamide prior to myeloablative hematopoietic stem cell transplantation.

Published in:

American Journal of Hematology, 2010, v. 85, n. 12, p. 967, doi. 10.1002/ajh.21889

By:

Melanson, Stacy E.F.;
Stevenson, Kristen;
Kim, Haesook;
Antin, Joseph H.;
Court, Michael H.;
Ho, Vincent T.;
Ritz, Jerome;
Soiffer, Robert J.;
Kuo, Frank C.;
Longtine, Janina A.;
Jarolim, Petr

Publication type:

Article

Assessment of cytochrome P450 induction in canine intestinal organoid models.

Published in:

Xenobiotica, 2024, v. 54, n. 5, p. 217, doi. 10.1080/00498254.2024.2326973

By:

Nagao, Itsuma;
Nakazawa, Meg;
Goyama, Takashi;
Court, Michael H.;
Ambrosini, Yoko M.

Publication type:

Article

Comparison of metabolomics and platelet aggregometry between Plavix and generic clopidogrel in cats: a pilot study.

Published in:

Journal of Feline Medicine & Surgery, 2019, v. 21, n. 10, p. 951, doi. 10.1177/1098612X18810887

By:

Malkawi, Mays;
Woolcock, Andrew D;
Lee, Pamela M;
Court, Michael H;
Moore, George E;
Hogan, Daniel F

Publication type:

Article

Genomes of Three Closely Related Caribbean Amazons Provide Insight for Species History and Conservation.

Published in:

Genes, 2019, v. 10, n. 1, p. 54, doi. 10.3390/genes10010054

By:

Kolchanova, Sofiia;
Kliver, Sergei;
Komissarov, Aleksei;
Dobrinin, Pavel;
Tamazian, Gaik;
Grigorev, Kirill;
Wolfsberger, Walter W.;
Majeske, Audrey J.;
Velez-Valentin, Jafet;
Valentin de la Rosa, Ricardo;
Paul-Murphy, Joanne R.;
Guzman, David Sanchez-Migallon;
Court, Michael H.;
Rodriguez-Flores, Juan L.;
Martínez-Cruzado, Juan Carlos;
Oleksyk, Taras K.

Publication type:

Article

Pharmacokinetics of a Sustained-release Formulation of Meloxicam After Subcutaneous Administration to Hispaniolan Amazon Parrots ( Amazona ventralis).

Published in:

Journal of Avian Medicine & Surgery, 2017, v. 31, n. 3, p. 219, doi. 10.1647/2016-202

By:

Guzman, David Sanchez-Migallon;
Court, Michael H.;
Zhu,, Zhaohui;
Summa, Noémie;
Paul-Murphy, Joanne R.

Publication type:

Article

The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats.

Published in:

Journal of Veterinary Internal Medicine, 2024, v. 38, n. 6, p. 3206, doi. 10.1111/jvim.17198

By:

Plante, Christina;
Lee, Pamela M.;
Haines, Jillian M.;
Nelson, O. Lynne;
Martinez, Stephanie E.;
Court, Michael H.

Publication type:

Article

Identification by whole genome sequencing of genes associated with delayed postoperative hemorrhage in Scottish deerhounds.

Published in:

Journal of Veterinary Internal Medicine, 2023, v. 37, n. 2, p. 510, doi. 10.1111/jvim.16643

By:

Court, Michael H.;
Kiser, Jennifer N.;
Neibergs, Holly L.;
Zhu, Zhaohui;
Dillberger, John E.

Publication type:

Article

Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen.

Published in:

British Journal of Clinical Pharmacology, 2015, v. 80, n. 5, p. 1076, doi. 10.1111/bcp.12644

By:

Zhao, Yanli;
Harmatz, Jerold S.;
Epstein, Carol R.;
Nakagawa, Yukako;
Kurosaki, Chie;
Nakamura, Tetsuro;
Kadota, Takumi;
Giesing, Dennis;
Court, Michael H.;
Greenblatt, David J.

Publication type:

Article

Biotransformation of Chlorzoxazone by Heptatic Microsomes from Humans and Ten Other Mammalian Species.

Published in:

Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 3, p. 213, doi. 10.1002/(SICI)1099-081X(199704)18:3<213::AID-BDD15>3.0.CO;2-0

By:

COURT, MICHAEL H.;
VON MOLTKE, LISA L.;
SHADER, RICHARD I.;
GREENBLATT, DAVID J.

Publication type:

Article

Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-019-56660-z

By:

Martinez, Stephanie E.;
Andresen, Marie C.;
Zhu, Zhaohui;
Papageorgiou, Ioannis;
Court, Michael H.

Publication type:

Article

Personalized medicine: going to the dogs?

Published in:

Human Genetics, 2019, v. 138, n. 5, p. 467, doi. 10.1007/s00439-019-02020-w

By:

Mealey, Katrina L.;
Martinez, Stephanie E.;
Villarino, Nicolas F.;
Court, Michael H.

Publication type:

Article

Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization.

Published in:

PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0297191

By:

Martinez, Stephanie E.;
Pandey, Amit V.;
Perez Jimenez, Tania E.;
Zhu, Zhaohui;
Court, Michael H.

Publication type:

Article

Evidence for epigenetic regulation of UGT1A1 protein expression and activity in healthy human livers.

Published in:

FASEB Journal, 2013, v. 27, p. 270.5, doi. 10.1096/fasebj.27.1_supplement.270.5

By:

Yasar, Umit;
Greenblatt, David J;
Guillemette, Chantal;
Court, Michael H.

Publication type:

Article

Evidence for regulation of UDP-glucuronosyltransferase ( UGT) 1 A1 protein expression and activity via DNA methylation in healthy human livers.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 6, p. 874, doi. 10.1111/jphp.12053

By:

Yasar, Umit;
Greenblatt, David J.;
Guillemette, Chantal;
Court, Michael H.

Publication type:

Article

Mechanism of cytochrome P450-3A inhibition by ketoconazole.

Published in:

Journal of Pharmacy & Pharmacology, 2011, v. 63, n. 2, p. 214, doi. 10.1111/j.2042-7158.2010.01202.x

By:

Greenblatt, David J.;
Zhao, Yanli;
Venkatakrishnan, Karthik;
Duan, Su X.;
Harmatz, Jerold S.;
Parent, Sarah J.;
Court, Michael H.;
von Moltke, Lisa L.

Publication type:

Article

Effect of the β-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.

Published in:

Journal of Pharmacy & Pharmacology, 2008, v. 60, n. 9, p. 1175, doi. 10.1211/jpp.60.9.0009

By:

Lauren Oleson;
Michael H. Court

Publication type:

Article

Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819

By:

Jill S. Warrington;
Michael H. Court;
David J. Greenblatt;
Lisa L. von Moltke

Publication type:

Article

Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819

By:

Jill S. Warrington;
Michael H. Court;
David J. Greenblatt;
Lisa L. von Moltke

Publication type:

Article

A genetic polymorphism in P2RY1 impacts response to clopidogrel in cats with hypertrophic cardiomyopathy.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91372-3

By:

Ueda, Yu;
Li, Ronald H. L.;
Nguyen, Nghi;
Ontiveros, Eric S.;
Kovacs, Samantha L.;
Oldach, Maureen S.;
Vernau, Karen M.;
Court, Michael H.;
Stern, Joshua A.

Publication type:

Article

Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 75, n. 4, p. 1041, doi. 10.1111/j.1365-2125.2012.04450.x

By:

Hanley, Michael J.;
Masse, Gina;
Harmatz, Jerold S.;
Cancalon, Paul F.;
Dolnikowski, Gregory G.;
Court, Michael H.;
Greenblatt, David J.

Publication type:

Article

Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 75, n. 2, p. 450, doi. 10.1111/j.1365-2125.2012.04364.x

By:

Volak, Laurie P.;
Hanley, Michael J.;
Masse, Gina;
Hazarika, Suwagmani;
Harmatz, Jerold S.;
Badmaev, Vladimir;
Majeed, Muhammed;
Greenblatt, David J.;
Court, Michael H.

Publication type:

Article

Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase.

Published in:

British Journal of Clinical Pharmacology, 2009, v. 68, n. 6, p. 920, doi. 10.1111/j.1365-2125.2009.03545.x

By:

Greenblatt, David J.;
Peters, Diane E.;
Oleson, Lauren E.;
Harmatz, Jerold S.;
MacNab, Malcolm W.;
Berkowitz, Noah;
Zinny, Miguel A.;
Court, Michael H.

Publication type:

Article

Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion.

Published in:

British Journal of Clinical Pharmacology, 2009, v. 68, n. 5, p. 721, doi. 10.1111/j.1365-2125.2009.03519.x

By:

Xi He;
Hesse, Leah M.;
Hazarika, Suwagmani;
Masse, Gina;
Harmatz, Jerold S.;
Greenblatt, David J.;
Court, Michael H.

Publication type:

Article

CYP2B6 (c.516G→T) and CYP2A6 (9B and/or 17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients.

Published in:

British Journal of Clinical Pharmacology, 2009, v. 67, n. 4, p. 427, doi. 10.1111/j.1365-2125.2009.03368.x

By:

Kwara, Awewura;
Lartey, Margaret;
Sagoe, Kwamena W.;
Rzek, Naser L.;
Court, Michael H.

Publication type:

Article

Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018046

By:

Shrestha, Binu;
Reed, J. Michael;
Starks, Philip T.;
Kaufman, Gretchen E.;
Goldstone, Jared V.;
Roelke, Melody E.;
O'Brien, Stephen J.;
Koepfli, Klaus-Peter;
Frank, Laurence G.;
Court, Michael H.

Publication type:

Article

Interindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV-Coinfected Ghanaian Patients: UGT2B7*1c Is Associated With Faster Zidovudine Clearance and Glucuronidation.

Published in:

Journal of Clinical Pharmacology, 2009, v. 49, n. 9, p. 1079, doi. 10.1177/0091270009338482

By:

Kwara, Awewura;
Lartey, Margaret;
Boamah, Isaac;
Rezk, Naser L.;
Oliver-Commey, Joseph;
Kenu, Ernest;
Kashuba, Angela D. M.;
Court, Michael H.

Publication type:

Article

Pharmacokinetics of Efavirenz When Co-administered With Rifampin in TB/HIV Co-infected Patients: Pharmacogenetic Effect of CYP2B6 Variation.

Published in:

Journal of Clinical Pharmacology, 2008, v. 48, n. 9, p. 1032, doi. 10.1177/0091270008321790

By:

Kwara, Awewura;
Lartey, Margaret;
Sagoe, Kwamena W.;
Xexemeku, Fafa;
Kenu, Ernest;
Oliver-Commey, Joseph;
Boima, Vincent;
Sagoe, Augustine;
Boamah, Isaac;
Greenblatt, David J.;
Court, Michael H.

Publication type:

Article

A Pharmacogenomics Primer.

Published in:

Journal of Clinical Pharmacology, 2007, v. 47, n. 9, p. 1087, doi. 10.1177/0091270007303768

By:

Court, Michael H.

Publication type:

Article

Human Pregnane X Receptor: Genetic Polymorphisms, Alternative mRNA Splice Variants, and Cytochrome P450 3A Metabolic Activity.

Published in:

Journal of Clinical Pharmacology, 2006, v. 46, n. 11, p. 1356, doi. 10.1177/0091270006292125

By:

He, Ping;
Court, Michael H.;
Greenblatt, David J.;
von Moltke, Lisa L.

Publication type:

Article

Ritonavir Has Minimal Impact on the Pharmacokinetic Disposition of a Single Dose of Bupropion Administered to Human Volunteers.

Published in:

Journal of Clinical Pharmacology, 2006, v. 46, n. 5, p. 567, doi. 10.1177/0091270006286981

By:

Hesse, Leah M.;
Greenblatt, David J.;
von Moltke, Lisa L.;
Court, Michael H.

Publication type:

Article

Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: Comparison with ritonavir<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 3, p. 243, doi. 10.1016/j.clpt.2005.11.009

By:

Culm-Merdek, Kerry E.;
von Moltke, Lisa L.;
Lu Gan;
Horan, Kelly A.;
Reynolds, Robyn;
Harmatz, Jerold S.;
Court, Michael H.;
Greenblatt, David J.

Publication type:

Article

Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo.

Published in:

Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 5, p. 373

By:

Ping He;
Court, Michael H.;
Greenblatt, David J.;
von Moltke, Lisa L.

Publication type:

Article

Factors Associated with Variability in Rifampin Plasma Pharmacokinetics and the Relationship between Rifampin Concentrations and Induction of Efavirenz Clearance.

Published in:

Pharmacotherapy, 2014, v. 34, n. 3, p. 265, doi. 10.1002/phar.1388

By:

Kwara, Awewura;
Cao, Lei;
Yang, Hongmei;
Poethke, Pamela;
Kurpewski, Jaclynn;
Tashima, Karen T.;
Mahjoub, Behrang D.;
Court, Michael H.;
Peloquin, Charles A.

Publication type:

Article

Simultaneous determination of mycophenolic acid and its glucuronide and glycoside derivatives in canine and feline plasma by UHPLC-UV.

Published in:

Biomedical Chromatography, 2017, v. 31, n. 8, p. n/a, doi. 10.1002/bmc.3942

By:

Rivera, Sol Maiam;
Hwang, Julianne K.;
Slovak, Jeniffer E.;
Court, Michael H.;
Villarino, Nicolas F.

Publication type:

Article

Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 202, doi. 10.3109/03602530903209288

By:

Court, Michael H.

Publication type:

Article