Works by Court, Michael H.
Results: 53
Biotransformation of Chlorzoxazone by Heptatic Microsomes from Humans and Ten Other Mammalian Species.
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- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 3, p. 213, doi. 10.1002/(SICI)1099-081X(199704)18:3<213::AID-BDD15>3.0.CO;2-0
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- Article
Personalized medicine: going to the dogs?
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- Human Genetics, 2019, v. 138, n. 5, p. 467, doi. 10.1007/s00439-019-02020-w
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- Article
Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.
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- Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 202, doi. 10.3109/03602530903209288
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- Article
Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-019-56660-z
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- Article
Factors Associated with Variability in Rifampin Plasma Pharmacokinetics and the Relationship between Rifampin Concentrations and Induction of Efavirenz Clearance.
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- Pharmacotherapy, 2014, v. 34, n. 3, p. 265, doi. 10.1002/phar.1388
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- Article
Evidence for regulation of UDP-glucuronosyltransferase ( UGT) 1 A1 protein expression and activity via DNA methylation in healthy human livers.
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- Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 6, p. 874, doi. 10.1111/jphp.12053
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- Article
Mechanism of cytochrome P450-3A inhibition by ketoconazole.
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- Journal of Pharmacy & Pharmacology, 2011, v. 63, n. 2, p. 214, doi. 10.1111/j.2042-7158.2010.01202.x
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- Article
Effect of the β-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.
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- Journal of Pharmacy & Pharmacology, 2008, v. 60, n. 9, p. 1175, doi. 10.1211/jpp.60.9.0009
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- Article
Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.
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- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819
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- Article
Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.
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- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819
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- Article
Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.
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- Journal of Antimicrobial Chemotherapy (JAC), 2014, v. 69, n. 8, p. 2175, doi. 10.1093/jac/dku110
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- Article
Genomes of Three Closely Related Caribbean Amazons Provide Insight for Species History and Conservation.
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- Genes, 2019, v. 10, n. 1, p. 54, doi. 10.3390/genes10010054
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- Article
Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization.
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- PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0297191
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- Article
Pharmacokinetics of a Sustained-release Formulation of Meloxicam After Subcutaneous Administration to Hispaniolan Amazon Parrots ( Amazona ventralis).
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- Journal of Avian Medicine & Surgery, 2017, v. 31, n. 3, p. 219, doi. 10.1647/2016-202
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- Article
Assessment of cytochrome P450 induction in canine intestinal organoid models.
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- Xenobiotica, 2024, v. 54, n. 5, p. 217, doi. 10.1080/00498254.2024.2326973
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- Article
Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms.
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- Xenobiotica, 2017, v. 47, n. 1, p. 1, doi. 10.3109/00498254.2016.1156784
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- Article
Soy isoflavone metabolism in cats compared with other species: urinary metabolite concentrations and glucuronidation by liver microsomes.
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- Xenobiotica, 2016, v. 46, n. 5, p. 406, doi. 10.3109/00498254.2015.1086038
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- Article
Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues.
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- Xenobiotica, 2012, v. 42, n. 3, p. 266, doi. 10.3109/00498254.2011.618954
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- Article
Comparison of metabolomics and platelet aggregometry between Plavix and generic clopidogrel in cats: a pilot study.
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- Journal of Feline Medicine & Surgery, 2019, v. 21, n. 10, p. 951, doi. 10.1177/1098612X18810887
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- Article
Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase.
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- British Journal of Clinical Pharmacology, 2009, v. 68, n. 6, p. 920, doi. 10.1111/j.1365-2125.2009.03545.x
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- Article
Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion.
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- British Journal of Clinical Pharmacology, 2009, v. 68, n. 5, p. 721, doi. 10.1111/j.1365-2125.2009.03519.x
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- Article
CYP2B6 (c.516G→T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients.
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- British Journal of Clinical Pharmacology, 2009, v. 67, n. 4, p. 427, doi. 10.1111/j.1365-2125.2009.03368.x
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- Article
Interindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV-Coinfected Ghanaian Patients: UGT2B7*1c Is Associated With Faster Zidovudine Clearance and Glucuronidation.
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- Journal of Clinical Pharmacology, 2009, v. 49, n. 9, p. 1079, doi. 10.1177/0091270009338482
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- Article
Pharmacokinetics of Efavirenz When Co-administered With Rifampin in TB/HIV Co-infected Patients: Pharmacogenetic Effect of CYP2B6 Variation.
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- Journal of Clinical Pharmacology, 2008, v. 48, n. 9, p. 1032, doi. 10.1177/0091270008321790
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- Article
A Pharmacogenomics Primer.
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- Journal of Clinical Pharmacology, 2007, v. 47, n. 9, p. 1087, doi. 10.1177/0091270007303768
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- Article
Human Pregnane X Receptor: Genetic Polymorphisms, Alternative mRNA Splice Variants, and Cytochrome P450 3A Metabolic Activity.
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- Journal of Clinical Pharmacology, 2006, v. 46, n. 11, p. 1356, doi. 10.1177/0091270006292125
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- Article
Ritonavir Has Minimal Impact on the Pharmacokinetic Disposition of a Single Dose of Bupropion Administered to Human Volunteers.
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- Journal of Clinical Pharmacology, 2006, v. 46, n. 5, p. 567, doi. 10.1177/0091270006286981
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- Article
Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: Comparison with ritonavir<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 3, p. 243, doi. 10.1016/j.clpt.2005.11.009
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- Article
Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo.
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- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 5, p. 373
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- Article
Response to Helsby and Tingle.
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- American Journal of Hematology, 2011, v. 86, n. 4, p. 384, doi. 10.1002/ajh.21997
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- Article
Allelic variations in CYP2B6 and CYP2C19 and survival of patients receiving cyclophosphamide prior to myeloablative hematopoietic stem cell transplantation.
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- American Journal of Hematology, 2010, v. 85, n. 12, p. 967, doi. 10.1002/ajh.21889
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- Article
Application of eprinomectin‐containing parasiticides at label doses causes neurological toxicosis in cats homozygous for ABCB11930_1931del TC.
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- Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 3, p. 226, doi. 10.1111/jvp.13431
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- Article
Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug–drug interactions involving canine cytochrome P‐450, UDP‐glucuronosyltransferase, and P‐glycoprotein.
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- Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 1, p. 1, doi. 10.1111/jvp.13403
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- Article
Association of cytochrome P450 2D15 (CYP2D15) nonsynonymous polymorphisms and exon 3 deleted RNA splice variant with CYP2D15 protein content and enzyme function in dog liver microsomes.
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- Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 2, p. 77, doi. 10.1111/jvp.13113
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- Article
Canine orosomucoid (alpha‐1 acid glycoprotein) variants and their influence on drug plasma protein binding.
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- Journal of Veterinary Pharmacology & Therapeutics, 2021, v. 44, n. 1, p. 116, doi. 10.1111/jvp.12899
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- Article
Investigation into the causes of aspirin resistance in healthy dogs.
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- Journal of Veterinary Pharmacology & Therapeutics, 2019, v. 42, n. 2, p. 160, doi. 10.1111/jvp.12725
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- Article
High interindividual variability in plasma clopidogrel active metabolite concentrations in healthy cats is associated with sex and cytochrome P450 2C genetic polymorphism.
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- Journal of Veterinary Pharmacology & Therapeutics, 2019, v. 42, n. 1, p. 16, doi. 10.1111/jvp.12717
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- Article
Identification of canine cytochrome P‐450s (CYPs) metabolizing the tramadol (+)‐M1 and (+)‐M2 metabolites to the tramadol (+)‐M5 metabolite in dog liver microsomes.
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- Journal of Veterinary Pharmacology & Therapeutics, 2018, v. 41, n. 6, p. 815, doi. 10.1111/jvp.12706
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- Article
Population variability in animal health: Influence on dose–exposure–response relationships: Part I: Drug metabolism and transporter systems.
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- Journal of Veterinary Pharmacology & Therapeutics, 2018, v. 41, n. 4, p. E57, doi. 10.1111/jvp.12670
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- Article
Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen.
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- British Journal of Clinical Pharmacology, 2015, v. 80, n. 5, p. 1076, doi. 10.1111/bcp.12644
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- Article
Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers.
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- British Journal of Clinical Pharmacology, 2013, v. 75, n. 4, p. 1041, doi. 10.1111/j.1365-2125.2012.04450.x
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- Article
Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers.
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- British Journal of Clinical Pharmacology, 2013, v. 75, n. 2, p. 450, doi. 10.1111/j.1365-2125.2012.04364.x
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- Article
Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus.
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- 2011
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- journal article
Simultaneous determination of mycophenolic acid and its glucuronide and glycoside derivatives in canine and feline plasma by UHPLC-UV.
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- Biomedical Chromatography, 2017, v. 31, n. 8, p. n/a, doi. 10.1002/bmc.3942
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- Article
A genetic polymorphism in P2RY1 impacts response to clopidogrel in cats with hypertrophic cardiomyopathy.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91372-3
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- Article
The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats.
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- Journal of Veterinary Internal Medicine, 2024, v. 38, n. 6, p. 3206, doi. 10.1111/jvim.17198
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- Article
Identification by whole genome sequencing of genes associated with delayed postoperative hemorrhage in Scottish deerhounds.
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- Journal of Veterinary Internal Medicine, 2023, v. 37, n. 2, p. 510, doi. 10.1111/jvim.16643
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- Article
Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory.
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- PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018046
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- Article
Measurement of Muscle Surface Capillary Blood Flow by Laser Doppler Flowmetry.
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- Veterinary Surgery, 1992, v. 21, n. 6, p. 491, doi. 10.1111/j.1532-950X.1992.tb00088.x
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- Article
Equine Post-anesthetic Lameness A Retrospective Study.
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- Veterinary Surgery, 1990, v. 19, n. 5, p. 392, doi. 10.1111/j.1532-950X.1990.tb01216.x
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- Article