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Solutions and dilutions: Mixing the math into the science.
- Published in:
- Science Scope, 2006, v. 29, n. 6, p. 60
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- Article
High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers.
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- NPJ Vaccines, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41541-022-00446-4
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- Article
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
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- PLoS Pathogens, 2018, v. 14, n. 2, p. 1, doi. 10.1371/journal.ppat.1006913
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- Article
Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
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- PLoS Biology, 2019, v. 17, n. 2, p. 1, doi. 10.1371/journal.pbio.3000139
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- Article
Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
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- NPJ Vaccines, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41541-020-00223-1
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- Article
Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34171-7
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- Article
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34171-7
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- Article
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01549-6
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- Article
High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination.
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- eLife, 2021, p. 1, doi. 10.7554/eLife.64281
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- Article
Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage.
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- Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01631
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- Article
The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.
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- PLoS Pathogens, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.ppat.1009257
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- Article
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
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- PLoS Pathogens, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.ppat.1008753
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- Article
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
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- PLoS Pathogens, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.ppat.1008665
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- Article
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25087-4
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- Article
Priming antibody responses to the fusion peptide in rhesus macaques.
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- NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00918-9
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- Article
Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming.
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- NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00811-5
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- Article
Optimization of an alum-anchored clinical HIV vaccine candidate.
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- NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00711-0
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- Article
mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models.
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- Science Immunology, 2024, v. 9, n. 95, p. 1, doi. 10.1126/sciimmunol.adn0622
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- Article
Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1180959
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Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12080-1
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- Article
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice.
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- Science Translational Medicine, 2024, v. 16, n. 748, p. 1, doi. 10.1126/scitranslmed.adn0223
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Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.
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- PLoS Pathogens, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.ppat.1009736
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Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer.
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- PLoS Pathogens, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.ppat.1008977
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Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
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- PLoS Pathogens, 2019, v. 15, n. 7, p. 1, doi. 10.1371/journal.ppat.1007920
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Use of Transient Transfection for cGMP Manufacturing of eOD-GT8 60mer, a Self-Assembling Nanoparticle Germline-Targeting HIV-1 Vaccine Candidate.
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- Pharmaceutics, 2024, v. 16, n. 6, p. 742, doi. 10.3390/pharmaceutics16060742
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