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Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33099-x
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- Article
Hyperpolarized δ-[1- <sup>13</sup>C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32463-1
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- Article
Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.
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- Metabolites (2218-1989), 2021, v. 11, n. 2, p. 109, doi. 10.3390/metabo11020109
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- Article
An Arrayed Human Not I-EcoRV Boundary Library as a Tool for RLGS Spot Analysis.
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- DNA Research, 1997, v. 4, n. 3, p. 253, doi. 10.1093/dnares/4.3.253
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- Article
Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser.
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- Nature Biotechnology, 2015, v. 33, n. 4, p. 345, doi. 10.1038/nbt.3158
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- Article
Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.
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- Nature Biotechnology, 2013, v. 31, n. 12, p. 1137, doi. 10.1038/nbt.2726
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- Article
The NIH Roadmap Epigenomics Mapping Consortium.
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- Nature Biotechnology, 2010, v. 28, n. 10, p. 1045, doi. 10.1038/nbt1010-1045
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- Article
A first look at entire human methylomes.
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- Nature Biotechnology, 2009, v. 27, n. 12, p. 1130, doi. 10.1038/nbt1209-1130
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- Article
A broad band of silence.
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- Nature Genetics, 2006, v. 38, n. 5, p. 504, doi. 10.1038/ng0506-504
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- Article
Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3.
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- Nature Genetics, 2005, v. 37, n. 6, p. 645, doi. 10.1038/ng1563
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- Article
Comparative epigenomics of leukemia.
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- Nature Genetics, 2005, v. 37, n. 3, p. 211, doi. 10.1038/ng0305-211
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- Article
Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors.
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- Nature Genetics, 2002, v. 32, n. 3, p. 453, doi. 10.1038/ng1007
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- Article
Methylation matters: a new spin on maspin.
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- Nature Genetics, 2002, v. 31, n. 2, p. 123, doi. 10.1038/ng0602-123
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- Article
Aberrant CpG-island methylation has non-random and tumour-type?specific patterns.
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- Nature Genetics, 2000, v. 24, n. 2, p. 132, doi. 10.1038/72785
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- Article
Exploring long-range genome interactions using the WashU Epigenome Browser.
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- Nature Methods, 2013, v. 10, n. 5, p. 375, doi. 10.1038/nmeth.2440
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- Article
The Human Epigenome Browser at Washington University.
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- Nature Methods, 2011, v. 8, n. 12, p. 989, doi. 10.1038/nmeth.1772
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- Article
Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury.
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- 2008
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- Publication type:
- journal article
Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury.
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- BMC Pulmonary Medicine, 2008, v. 8, p. 1, doi. 10.1186/1471-2466-8-9
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- Article
Molecular signatures define two main classes of meningiomas.
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- Molecular Cancer, 2007, v. 6, p. 64, doi. 10.1186/1476-4598-6-64
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- Article
Characterization of the Contradictory Chromatin Signatures at the 3' Exons of Zinc Finger Genes.
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- PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0017121
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- Article
Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11526-w
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- Article
Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections.
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- Cancers, 2024, v. 16, n. 13, p. 2429, doi. 10.3390/cancers16132429
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- Article
Moving AHEAD with an international human epigenome project.
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- Nature, 2008, v. 454, n. 7205, p. 711, doi. 10.1038/454711a
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- Article
Stem cells: Tips for priming potency.
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- Nature, 2008, v. 454, n. 7200, p. 45, doi. 10.1038/454045a
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- Article
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.
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- Nature Cell Biology, 2011, v. 13, n. 5, p. 541, doi. 10.1038/ncb2239
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- Article
Spatial concordance of DNA methylation classification in diffuse glioma.
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- Neuro-Oncology, 2021, v. 23, n. 12, p. 2054, doi. 10.1093/neuonc/noab134
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- Article
Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
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- Neuro-Oncology, 2021, v. 23, n. 9, p. 1509, doi. 10.1093/neuonc/noab093
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- Article
Functional analysis of low-grade glioma genetic variants predicts key target genes and transcription factors.
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- Neuro-Oncology, 2021, v. 23, n. 4, p. 638, doi. 10.1093/neuonc/noaa248
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- Article
MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence.
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- Neuro-Oncology, 2020, v. 22, n. 11, p. 1580, doi. 10.1093/neuonc/noaa059
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- Article
Temozolomide-associated hypermutation in gliomas.
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- Neuro-Oncology, 2018, v. 20, n. 10, p. 1300, doi. 10.1093/neuonc/noy016
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- Article
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium.
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- Neuro-Oncology, 2018, v. 20, n. 7, p. 873, doi. 10.1093/neuonc/noy020
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- Article
Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide.
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- Neuro-Oncology, 2017, v. 19, n. 2, p. 242, doi. 10.1093/neuonc/now176
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- Article
CLONAL EVOLUTION OF GLIOMAS IS ENCODED IN THE EVOLUTIONARY DYNAMICS OF DNA METHYLATION.
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- Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii51, doi. 10.1093/neuonc/nou209.38
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- Article
A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma.
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- Neuro-Oncology, 2014, v. 16, n. 7, p. 984, doi. 10.1093/neuonc/nou029
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- Article
Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.
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- Neuro-Oncology, 2014, v. 16, n. 3, p. 361, doi. 10.1093/neuonc/not223
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- Article
Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) Low-grade Glioma Research Workshop.
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- Neuro-Oncology, 2014, v. 16, n. 2, p. 173, doi. 10.1093/neuonc/not229
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- Article
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
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- Neuro-Oncology, 2011, v. 13, n. 12, p. 1331, doi. 10.1093/neuonc/nor130
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- Article
Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome.
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- G3: Genes | Genomes | Genetics, 2016, v. 6, n. 4, p. 973, doi. 10.1534/g3.115.025437
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- Article
Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas.
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- 2017
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- Publication type:
- journal article
Regulatory network decoded from epigenomes of surface ectoderm-derived cell types.
- Published in:
- Nature Communications, 2014, v. 5, n. 11, p. 5442, doi. 10.1038/ncomms6442
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- Article
To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes.
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- Frontiers in Genetics, 2018, p. 1, doi. 10.3389/fgene.2018.00298
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- Article
Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness.
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- Human Molecular Genetics, 2013, v. 22, n. 1, p. 84, doi. 10.1093/hmg/dds405
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- Publication type:
- Article
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02178-9
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- Publication type:
- Article
Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas.
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- 2017
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- Publication type:
- journal article
Epigenetic silencing of MIR203 in multiple myeloma.
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- British Journal of Haematology, 2011, v. 154, n. 5, p. 569, doi. 10.1111/j.1365-2141.2011.08782.x
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- Article
Telomeres in glioma: Maintenance mechanisms to therapeutic potential.
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- Neuro-Oncology, 2024, v. 26, n. 6, p. 1025, doi. 10.1093/neuonc/noae052
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- Article
Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression.
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- Neuro-Oncology, 2024, v. 26, n. 4, p. 640, doi. 10.1093/neuonc/noad231
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- Publication type:
- Article
Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions.
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- Neuro-Oncology, 2023, v. 25, n. 1, p. 4, doi. 10.1093/neuonc/noac207
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- Article
TERT promoter C228T mutation in neural progenitors confers growth advantage following telomere shortening in vivo.
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- Neuro-Oncology, 2022, v. 24, n. 12, p. 2063, doi. 10.1093/neuonc/noac080
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- Article
Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.
- Published in:
- Neuro-Oncology, 2022, v. 24, n. 11, p. 1898, doi. 10.1093/neuonc/noac112
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- Article