Works by Cosconati, Sandro

Results: 35

The G-Triplex DNA.

Published in:

Angewandte Chemie, 2013, v. 125, n. 8, p. 2325, doi. 10.1002/ange.201206522

By:

Limongelli, Vittorio;
De Tito, Stefano;
Cerofolini, Linda;
Fragai, Marco;
Pagano, Bruno;
Trotta, Roberta;
Cosconati, Sandro;
Marinelli, Luciana;
Novellino, Ettore;
Bertini, Ivano;
Randazzo, Antonio;
Luchinat, Claudio;
Parrinello, Michele

Publication type:

Article

Erhöhte CXCR4-Affinität und Anti-HIV-Aktivität eines Peptoids durch Konformationsfixierung.

Published in:

Angewandte Chemie, 2012, v. 124, n. 32, p. 8234, doi. 10.1002/ange.201202090

By:

Demmer, Oliver;
Frank, Andreas O.;
Hagn, Franz;
Schottelius, Margret;
Marinelli, Luciana;
Cosconati, Sandro;
Brack-Werner, Ruth;
Kremb, Stephan;
Wester, Hans-Jürgen;
Kessler, Horst

Publication type:

Article

Erhöhung der αvβ3-Selektivität des Angiogenese hemmenden Wirkstoffs Cilengitid durch N-Methylierung.

Published in:

Angewandte Chemie, 2011, v. 123, n. 40, p. 9668, doi. 10.1002/ange.201102971

By:

Mas-Moruno, Carlos;
Beck, Johannes G.;
Doedens, Lucas;
Frank, Andreas O.;
Marinelli, Luciana;
Cosconati, Sandro;
Novellino, Ettore;
Kessler, Horst

Publication type:

Article

Konformative Kontrolle über Integrin-Subtyp-Selektivitäten in isoDGR-Peptidmotiven: ein biologischer Schalter.

Published in:

Angewandte Chemie, 2010, v. 122, n. 48, p. 9465, doi. 10.1002/ange.201004363

By:

Frank, Andreas O.;
Otto, Elke;
Mas-Moruno, Carlos;
Schiller, Herbert B.;
Marinelli, Luciana;
Cosconati, Sandro;
Bochen, Alexander;
Vossmeyer, Dörte;
Zahn, Grit;
Stragies, Roland;
Novellino, Ettore;
Kessler, Horst

Publication type:

Article

Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3765, doi. 10.3390/molecules27123765

By:

Previti, Santo;
Ettari, Roberta;
Di Chio, Carla;
Ravichandran, Rahul;
Bogacz, Marta;
Hellmich, Ute A.;
Schirmeister, Tanja;
Cosconati, Sandro;
Zappalà, Maria

Publication type:

Article

Best Matching Protein Conformations and Docking Programs for a Virtual Screening Campaign Against SMO Receptor.

Published in:

Molecular Informatics, 2016, v. 35, n. 8/9, p. 340, doi. 10.1002/minf.201501021

By:

Amendola, Giorgio;
Di Maio, Danilo;
La Pietra, Valeria;
Cosconati, Sandro

Publication type:

Article

Peptidyl Vinyl Ketone Irreversible Inhibitors of Rhodesain: Modifications of the P2 Fragment.

Published in:

ChemMedChem, 2020, v. 15, n. 16, p. 1552, doi. 10.1002/cmdc.202000360

By:

Maiorana, Santina;
Ettari, Roberta;
Previti, Santo;
Amendola, Giorgio;
Wagner, Annika;
Cosconati, Sandro;
Hellmich, Ute A.;
Schirmeister, Tanja;
Zappalà, Maria

Publication type:

Article

Development of Novel Benzodiazepine‐Based Peptidomimetics as Inhibitors of Rhodesain from Trypanosoma brucei rhodesiense.

Published in:

ChemMedChem, 2020, v. 15, n. 11, p. 995, doi. 10.1002/cmdc.202000158

By:

Di Chio, Carla;
Previti, Santo;
Amendola, Giorgio;
Cosconati, Sandro;
Schirmeister, Tanja;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Residence Time, a New parameter to Predict Neurosteroidogenic Efficacy of Translocator Protein (TSPO) Ligands: the Case Study of N, N-Dialkyl-2-arylindol-3-ylglyoxylamides.

Published in:

ChemMedChem, 2017, v. 12, n. 16, p. 1275, doi. 10.1002/cmdc.201700220

By:

Costa, Barbara;
Taliani, Sabrina;
Da Pozzo, Eleonora;
Barresi, Elisabetta;
Robello, Marco;
Cavallini, Chiara;
Cosconati, Sandro;
Da Settimo, Federico;
Novellino, Ettore;
Martini, Claudia

Publication type:

Article

Cover Picture: tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells (ChemMedChem 5/2013).

Published in:

ChemMedChem, 2013, v. 8, n. 5, p. 673, doi. 10.1002/cmdc.201390015

By:

Valente, Sergio;
Trisciuoglio, Daniela;
Tardugno, Maria;
Benedetti, Rosaria;
Labella, Donatella;
Secci, Daniela;
Mercurio, Ciro;
Boggio, Roberto;
Tomassi, Stefano;
Di Maro, Salvatore;
Novellino, Ettore;
Altucci, Lucia;
Del Bufalo, Donatella;
Mai, Antonello;
Cosconati, Sandro

Publication type:

Article

tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells.

Published in:

ChemMedChem, 2013, v. 8, n. 5, p. 800, doi. 10.1002/cmdc.201300005

By:

Valente, Sergio;
Trisciuoglio, Daniela;
Tardugno, Maria;
Benedetti, Rosaria;
Labella, Donatella;
Secci, Daniela;
Mercurio, Ciro;
Boggio, Roberto;
Tomassi, Stefano;
Di Maro, Salvatore;
Novellino, Ettore;
Altucci, Lucia;
Del Bufalo, Donatella;
Mai, Antonello;
Cosconati, Sandro

Publication type:

Article

Synthesis and Biological Evaluation of CTP Synthetase Inhibitors as Potential Agents for the Treatment of African Trypanosomiasis.

Published in:

ChemMedChem, 2012, v. 7, n. 9, p. 1623, doi. 10.1002/cmdc.201200304

By:

Tamborini, Lucia;
Pinto, Andrea;
Smith, Terry K.;
Major, Louise L.;
Iannuzzi, Maria C.;
Cosconati, Sandro;
Marinelli, Luciana;
Novellino, Ettore;
Lo Presti, Leonardo;
Wong, Pui E.;
Barrett, Michael P.;
De Micheli, Carlo;
Conti, Paola

Publication type:

Article

Homology Modeling of NR2B Modulatory Domain of NMDA Receptor and Analysis of Ifenprodil Binding.

Published in:

ChemMedChem, 2007, v. 2, n. 10, p. 1498, doi. 10.1002/cmdc.200700091

By:

Marinelli, Luciana;
Cosconati, Sandro;
Steinbrecher, Thomas;
Limongelli, Vittorio;
Bertamino, Alessia;
Novellino, Ettore;
Case, David A.

Publication type:

Article

Ensemble-Docking Approach on BACE-1: Pharmacophore Perception and Guidelines for Drug Design.

Published in:

ChemMedChem, 2007, v. 2, n. 6, p. 740, doi. 10.1002/cmdc.200790018

By:

Limongelli, Vittorio;
Marinelli, Luciana;
Cosconati, Sandro;
Braun, Hannes A.;
Schmidt, Boris;
Novellino, Ettore

Publication type:

Article

Cover Picture: Ensemble-Docking Approach on BACE-1: Pharmacophore Perception and Guidelines for Drug Design (ChemMedChem 5/2007).

Published in:

ChemMedChem, 2007, v. 2, n. 5, p. 569, doi. 10.1002/cmdc.200790012

By:

Limongelli, Vittorio;
Marinelli, Luciana;
Cosconati, Sandro;
Braun, Hannes A.;
Schmidt, Boris;
Novellino, Ettore

Publication type:

Article

Ensemble-Docking Approach on BACE-1: Pharmacophore Perception and Guidelines for Drug Design.

Published in:

ChemMedChem, 2007, v. 2, n. 5, p. 667, doi. 10.1002/cmdc.200600314

By:

Limongelli, Vittorio;
Marinelli, Luciana;
Cosconati, Sandro;
Braun, Hannes A.;
Schmidt, Boris;
Novellino, Ettore

Publication type:

Article

Modeling of Cdc25B Dual Specifity Protein Phosphatase Inhibitors: Docking of Ligands and Enzymatic Inhibition Mechanism.

Published in:

ChemMedChem, 2006, v. 1, n. 5, p. 540, doi. 10.1002/cmdc.200500092

By:

Lavecchia, Antonio;
Cosconati, Sandro;
Limongelli, Vittorio;
Novellino, Ettore

Publication type:

Article

The G-Triplex DNA.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 8, p. 2269, doi. 10.1002/anie.201206522

By:

Limongelli, Vittorio;
De Tito, Stefano;
Cerofolini, Linda;
Fragai, Marco;
Pagano, Bruno;
Trotta, Roberta;
Cosconati, Sandro;
Marinelli, Luciana;
Novellino, Ettore;
Bertini, Ivano;
Randazzo, Antonio;
Luchinat, Claudio;
Parrinello, Michele

Publication type:

Article

A Conformationally Frozen Peptoid Boosts CXCR4 Affinity and Anti-HIV Activity.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 32, p. 8110, doi. 10.1002/anie.201202090

By:

Demmer, Oliver;
Frank, Andreas O.;
Hagn, Franz;
Schottelius, Margret;
Marinelli, Luciana;
Cosconati, Sandro;
Brack-Werner, Ruth;
Kremb, Stephan;
Wester, Hans-Jürgen;
Kessler, Horst

Publication type:

Article

Increasing αvβ3 Selectivity of the Anti-Angiogenic Drug Cilengitide by N-Methylation.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 40, p. 9496, doi. 10.1002/anie.201102971

By:

Mas-Moruno, Carlos;
Beck, Johannes G.;
Doedens, Lucas;
Frank, Andreas O.;
Marinelli, Luciana;
Cosconati, Sandro;
Novellino, Ettore;
Kessler, Horst

Publication type:

Article

Conformational Control of Integrin-Subtype Selectivity in isoDGR Peptide Motifs: A Biological Switch.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 48, p. 9278, doi. 10.1002/anie.201004363

By:

Frank, Andreas O.;
Otto, Elke;
Mas-Moruno, Carlos;
Schiller, Herbert B.;
Marinelli, Luciana;
Cosconati, Sandro;
Bochen, Alexander;
Vossmeyer, Dörte;
Zahn, Grit;
Stragies, Roland;
Novellino, Ettore;
Kessler, Horst

Publication type:

Article

Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4410, doi. 10.3390/ijms25084410

By:

Di Chio, Carla;
Starvaggi, Josè;
Totaro, Noemi;
Previti, Santo;
Natale, Benito;
Cosconati, Sandro;
Bogacz, Marta;
Schirmeister, Tanja;
Legac, Jenny;
Rosenthal, Philip J.;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Olive Leaves and Hibiscus Flowers Extracts-Based Preparation Protect Brain from Oxidative Stress-Induced Injury.

Published in:

Antioxidants, 2020, v. 9, n. 9, p. 806, doi. 10.3390/antiox9090806

By:

Chiaino, Elda;
Micucci, Matteo;
Cosconati, Sandro;
Novellino, Ettore;
Budriesi, Roberta;
Chiarini, Alberto;
Frosini, Maria

Publication type:

Article

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 4, p. 1820, doi. 10.1093/nar/gkw1202

By:

Rizzo, Angela;
Iachettini, Sara;
Salvati, Erica;
Zizza, Pasquale;
Maresca, Carmen;
D’Angelo, Carmen;
Benarroch-Popivker, Delphine;
Capolupo, Angela;
del Gaudio, Federica;
Cosconati, Sandro;
DiMaro, Salvatore;
Merlino, Francesco;
Novellino, Ettore;
Amoreo, Carla Azzurra;
Mottolese, Marcella;
Sperduti, Isabella;
Gilson, Eric;
Biroccio, Annamaria

Publication type:

Article

Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence.

Published in:

Epigenetics, 2020, v. 15, n. 6/7, p. 664, doi. 10.1080/15592294.2019.1704349

By:

Scisciola, Lucia;
Sarno, Federica;
Carafa, Vincenzo;
Cosconati, Sandro;
Di Maro, Salvatore;
Ciuffreda, Loreta;
De Angelis, Antonella;
Stiuso, Paola;
Feoli, Alessandra;
Sbardella, Gianluca;
Altucci, Lucia;
Nebbioso, Angela

Publication type:

Article

Properly Substituted Analogues of BIX-01294 Lose Inhibition of G9a Histone Methyltransferase and Gain Selective Anti-DNA Methyltransferase 3A Activity.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096941

By:

Rotili, Dante;
Tarantino, Domenico;
Marrocco, Biagina;
Gros, Christina;
Masson, Véronique;
Poughon, Valérie;
Ausseil, Fréderic;
Chang, Yanqi;
Labella, Donatella;
Cosconati, Sandro;
Di Maro, Salvatore;
Novellino, Ettore;
Schnekenburger, Michael;
Grandjenette, Cindy;
Bouvy, Celine;
Diederich, Marc;
Cheng, Xiaodong;
Arimondo, Paola B.;
Mai, Antonello

Publication type:

Article

Disulfide Bond Replacement with 1,4‐ and 1,5‐Disubstituted [1,2,3]‐Triazole on C‐X‐C Chemokine Receptor Type 4 (CXCR4) Peptide Ligands: Small Changes that Make Big Differences.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 44, p. 10113, doi. 10.1002/chem.202002468

By:

Tomassi, Stefano;
Trotta, Anna Maria;
Ieranò, Caterina;
Merlino, Francesco;
Messere, Anna;
Rea, Giuseppina;
Santoro, Federica;
Brancaccio, Diego;
Carotenuto, Alfonso;
D'Amore, Vincenzo Maria;
Di Leva, Francesco Saverio;
Novellino, Ettore;
Cosconati, Sandro;
Marinelli, Luciana;
Scala, Stefania;
Di Maro, Salvatore

Publication type:

Article

Carbonic anhydrase activation profile of indole-based derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1783, doi. 10.1080/14756366.2021.1959573

By:

Barresi, Elisabetta;
Ravichandran, Rahul;
Germelli, Lorenzo;
Angeli, Andrea;
Baglini, Emma;
Salerno, Silvia;
Marini, Anna Maria;
Costa, Barbara;
Da Pozzo, Eleonora;
Martini, Claudia;
Da Settimo, Federico;
Supuran, Claudiu;
Cosconati, Sandro;
Taliani, Sabrina

Publication type:

Article

Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1874, doi. 10.1080/14756366.2021.1956913

By:

Baglini, Emma;
Ravichandran, Rahul;
Berrino, Emanuela;
Salerno, Silvia;
Barresi, Elisabetta;
Marini, Anna Maria;
Viviano, Monica;
Castellano, Sabrina;
Da Settimo, Federico;
Supuran, Claudiu T.;
Cosconati, Sandro;
Taliani, Sabrina

Publication type:

Article

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1697, doi. 10.1080/14756366.2019.1666836

By:

Milite, Ciro;
Amendola, Giorgio;
Nocentini, Alessio;
Bua, Silvia;
Cipriano, Alessandra;
Barresi, Elisabetta;
Feoli, Alessandra;
Novellino, Ettore;
Da Settimo, Federico;
Supuran, Claudiu T.;
Castellano, Sabrina;
Cosconati, Sandro;
Taliani, Sabrina

Publication type:

Article

Identification of novel indole derivatives acting as inhibitors of the Keap1–Nrf2 interaction.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1152, doi. 10.1080/14756366.2019.1623209

By:

Cosimelli, Barbara;
Greco, Giovanni;
Laneri, Sonia;
Novellino, Ettore;
Sacchi, Antonia;
Amendola, Giorgio;
Cosconati, Sandro;
Bortolozzi, Roberta;
Viola, Giampietro

Publication type:

Article

Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1184, doi. 10.3109/14756366.2015.1108972

By:

Ettari, Roberta;
Previti, Santo;
Cosconati, Sandro;
Kesselring, Jochen;
Schirmeister, Tanja;
Grasso, Silvana;
Zappalà, Maria

Publication type:

Article

Synthesis and Gene Silencing Properties of siRNAs Containing Terminal Amide Linkages.

Published in:

2014

By:

Gaglione, Maria;
Mercurio, M Emilia;
Potenza, Nicoletta;
Mosca, Nicola;
Russo, Aniello;
Novellino, Ettore;
Cosconati, Sandro;
Messere, Anna

Publication type:

Journal Article

Synthesis and Gene Silencing Properties of siRNAs Containing Terminal Amide Linkages.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/901617

By:

Gaglione, Maria;
Mercurio, M. Emilia;
Potenza, Nicoletta;
Mosca, Nicola;
Russo, Aniello;
Novellino, Ettore;
Cosconati, Sandro;
Messere, Anna

Publication type:

Article

A novel smaller β‐defensin‐derived peptide is active against multidrug‐resistant bacterial strains.

Published in:

FASEB Journal, 2021, v. 35, n. 12, p. 1, doi. 10.1096/fj.202002330RR

By:

Colicchio, Roberta;
Nigro, Ersilia;
Colavita, Irene;
Pagliuca, Chiara;
Di Maro, Salvatore;
Tomassi, Stefano;
Scaglione, Elena;
Carbone, Fortunata;
Carriero, Maria Vincenza;
Matarese, Giuseppe;
Daniele, Aurora;
Cosconati, Sandro;
Pessi, Antonello;
Salvatore, Francesco;
Salvatore, Paola

Publication type:

Article