Works by Cortopassi, Gino

Results: 51

Shc inhibitor idebenone ameliorates liver injury and fibrosis in dietary NASH in mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 10, p. 1, doi. 10.1002/jbt.22876

By:

Jiang, Joy X.;
Tomilov, Alexey;
Montgomery, Claire;
Hui, Chun Kui;
Török, Natalie J.;
Cortopassi, Gino

Publication type:

Article

The Influence of Shc Proteins on Life Span in Mice.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. 10, p. 1177, doi. 10.1093/gerona/glt198

By:

Ramsey, Jon J.;
Tran, Dianna;
Giorgio, Marco;
Griffey, Stephen M.;
Koehne, Amanda;
Laing, Steven T.;
Taylor, Sandra L.;
Kim, Kyoungmi;
Cortopassi, Gino A.;
Lloyd, K. C. Kent;
Hagopian, Kevork;
Tomilov, Alexey A.;
Migliaccio, Enrica;
Pelicci, Pier Giuseppe;
McDonald, Roger B.

Publication type:

Article

Dysregulation of Glutamine Transporter SNAT1 in Rett Syndrome Microglia: A Mechanism for Mitochondrial Dysfunction and Neurotoxicity.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 6, p. 2516, doi. 10.1523/JNEUROSCI.2778-14.2015

By:

Jin, Lee-Way;
Horiuchi, Makoto;
Wulff, Heike;
Xiao-Bo Liu;
Cortopassi, Gino A.;
Erickson, Jeffrey D.;
Maezawa, Izumi

Publication type:

Article

The ketone body β‐hydroxybutyrate shifts microglial metabolism and suppresses amyloid‐β oligomer‐induced inflammation in human microglia.

Published in:

FASEB Journal, 2023, v. 37, n. 11, p. 1, doi. 10.1096/fj.202301254R

By:

Jin, Lee‐Way;
Di Lucente, Jacopo;
Ruiz Mendiola, Ulises;
Suthprasertporn, Nopparat;
Tomilov, Alexey;
Cortopassi, Gino;
Kim, Kyoungmi;
Ramsey, Jon J.;
Maezawa, Izumi

Publication type:

Article

Correlated mutagenesis of bcl2 and hprt loci in blood lymphocytes.

Published in:

Environmental & Molecular Mutagenesis, 1997, v. 29, n. 1, p. 36, doi. 10.1002/(SICI)1098-2280(1997)29:1<36::AID-EM5>3.0.CO;2-B

By:

Liu, Yafei;
Cortopassi, Gino;
Steingrimsdottir, Herdis;
Waugh, Alastair P.W.;
Beare, David M.;
Green, Michael H.L.;
Robinson, Derek R.;
Cole, Jane

Publication type:

Article

Genetic analysis of a switch in cell specificity of P lysozyme expression in molossinus mice.

Published in:

Genetics Research, 1991, v. 58, n. 2, p. 111, doi. 10.1017/S001667230002975X

By:

Cortopassi, Gino A.;
Wilson, Allan C.

Publication type:

Article

Novel mTORC1 Inhibitors Kill Glioblastoma Stem Cells.

Published in:

Pharmaceuticals (14248247), 2020, v. 13, n. 12, p. 419, doi. 10.3390/ph13120419

By:

Sandoval, Jose A.;
Tomilov, Alexey;
Datta, Sandipan;
Allen, Sonia;
O'Donnell, Robert;
Sears, Thomas;
Woolard, Kevin;
Kovalskyy, Dmytro;
Angelastro, James M.;
Cortopassi, Gino

Publication type:

Article

Potential biomarker identification for Friedreich's ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion.

Published in:

PLoS ONE, 2019, v. 14, n. 10, p. 1, doi. 10.1371/journal.pone.0223209

By:

McMackin, Marissa Z.;
Durbin-Johnson, Blythe;
Napierala, Marek;
Napierala, Jill S.;
Ruiz, Luis;
Napoli, Eleonora;
Perlman, Susan;
Giulivi, Cecilia;
Cortopassi, Gino A.

Publication type:

Article

Androgen receptor-dependent regulation of metabolism in high grade bladder cancer cells.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28692-z

By:

Katleba, Kimberley D.;
Tsamouri, Maria-Malvina;
Jathal, Maitreyee;
Baek, Han Bit;
Armenta, Rebecca B.;
Tepper, Clifford G.;
Cortopassi, Gino;
Ghosh, Paramita M.;
Mudryj, Maria

Publication type:

Article

Dimethyl fumarate dose-dependently increases mitochondrial gene expression and function in muscle and brain of Friedreich's ataxia model mice.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 24, p. 3954, doi. 10.1093/hmg/ddaa282

By:

Hui, Chun Kiu;
Dedkova, Elena N;
Montgomery, Claire;
Cortopassi, Gino

Publication type:

Article

Lymphoblast Oxidative Stress Genes as Potential Biomarkers of Disease Severity and Drug Effect in Friedreich's Ataxia.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153574

By:

Hayashi, Genki;
Cortopassi, Gino

Publication type:

Article

Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151026

By:

Shen, Yan;
McMackin, Marissa Z.;
Shan, Yuxi;
Raetz, Alan;
David, Sheila;
Cortopassi, Gino

Publication type:

Article

Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.

Published in:

Human Molecular Genetics, 2007, v. 16, n. 8, p. 929, doi. 10.1093/hmg/ddm038

By:

Shan, Yuxi;
Napoli, Eleonora;
Cortopassi, Gino

Publication type:

Article

Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 24, p. 3787, doi. 10.1093/hmg/ddi393

By:

Schoenfeld, Robert A.;
Napoli, Eleonora;
Wong, Alice;
Zhan, Shan;
Reutenauer, Laurence;
Morin, Dexter;
Buckpitt, Alan R.;
Taroni, Franco;
Lonnerdal, Bo;
Ristow, Michael;
Puccio, Hélène;
Cortopassi, Gino A.

Publication type:

Article

Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 14, p. 1699, doi. 10.1093/hmg/ddg187

By:

Tan, Guolin;
Napoli, Eleonora;
Taroni, Franco;
Cortopassi, Gino

Publication type:

Article

Differentiation-specific effectsof LHON mutations introduced into neuronal NT2 cells.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 4, p. 431, doi. 10.1093/hmg/11.4.431

By:

Wong, Alice;
Cavelier, Lucia;
Collins-Schramm, Heather E.;
Seldin, Michael F.;
McGrogan, Michael;
Savontaus, Marja-Liisa;
Cortopassi, Gino A.

Publication type:

Article

Frataxin expression rescues mitochondrial dysfunctions in FRDA cells.

Published in:

Human Molecular Genetics, 2001, v. 10, n. 19, p. 2099, doi. 10.1093/hmg/10.19.2099

By:

Tan, Guolin;
Chen, Li-Sheng;
Lonnerdal, Bo;
Gellera, Cinzia;
Taroni, Franco A.;
Cortopassi, Gino A.

Publication type:

Article

The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis.

Published in:

Human Molecular Genetics, 1999, v. 8, n. 3, p. 425, doi. 10.1093/hmg/8.3.425

By:

Wong, Alice;
Yang, Joy;
Cavadini, Patrizia;
Gellera, Cinzia;
Lonnerdal, Bo;
Taroni, Franco;
Cortopassi, Gino

Publication type:

Article

Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0177761

By:

Scharadin, Tiffany M.;
He, Wei;
Yiannakou, Yianni;
Tomilov, Alexey A.;
Saldana, Matthew;
Cortopassi, Gino A.;
IIICarraway, Kermit L.;
Coleman, Matthew A.;
Henderson, Paul T.

Publication type:

Article

Isolation of transcriptomal changes attributable to LHON mutations and the cybridization process.

Published in:

Brain: A Journal of Neurology, 2005, v. 128, n. 5, p. 1026, doi. 10.1093/brain/awh447

By:

Steven R. Danielson;
Valerio Carelli;
Guolin Tan;
Andrea Martinuzzi;
Anthony H. V. Schapira;
Marja-Liisa Savontaus;
Gino A. Cortopassi

Publication type:

Article

The Histone H3 K4me3, K27me3, and K27ac Genome-Wide Distributions Are Differently Influenced by Sex in Brain Cortexes and Gastrocnemius of the Alzheimer's Disease PSAPP Mouse Model.

Published in:

Epigenomes, 2021, v. 5, n. 4, p. 1, doi. 10.3390/epigenomes5040026

By:

Casciaro, Francesca;
Persico, Giuseppe;
Rusin, Martina;
Amatori, Stefano;
Montgomery, Claire;
Rutkowsky, Jennifer R.;
Ramsey, Jon J.;
Cortopassi, Gino;
Fanelli, Mirco;
Giorgio, Marco

Publication type:

Article

Omaveloxolone, But Not Dimethyl Fumarate, Improves Cardiac Function in Friedreich’s Ataxia Mice With Severe Cardiomyopathy.

Published in:

Journal of the American Heart Association, 2025, v. 14, n. 12, p. 1, doi. 10.1161/JAHA.124.038505

By:

Salinas, Lili;
Figueroa, Francisco;
Montgomery, Claire B.;
Thai, Phung N.;
Chiamvimonvat, Nipavan;
Cortopassi, Gino;
Dedkova, Elena N.

Publication type:

Article

A descriptive pilot study of cytokine production following stimulation of ex-vivo whole blood with commercial therapeutic feline hydrolyzed diets in individual healthy immunotolerant cats.

Published in:

BMC Veterinary Research, 2017, v. 13, p. 1, doi. 10.1186/s12917-017-1219-9

By:

Kathrani, Aarti;
Larsen, Jennifer A.;
Cortopassi, Gino;
Datta, Sandipan;
Fascetti, Andrea J.

Publication type:

Article

Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin.

Published in:

GeroScience, 2024, v. 46, n. 5, p. 4657, doi. 10.1007/s11357-024-01176-2

By:

Miller, Richard A.;
Harrison, David E.;
Cortopassi, Gino A.;
Dehghan, Ishmael;
Fernandez, Elizabeth;
Garratt, Michael;
Geisler, John G.;
Ginsburg, Brett C.;
Han, Melissa L.;
Kaczorowski, Catherine C.;
Kumar, Navasuja;
Leiser, Scott F.;
Lopez-Cruzan, Marisa;
Milne, Ginger;
Mitchell, James R.;
Nelson, James F.;
Reifsnyder, Peter C.;
Salmon, Adam B.;
Korstanje, Ron;
Rosenthal, Nadia

Publication type:

Article

Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used.

Published in:

GeroScience, 2024, v. 46, n. 1, p. 795, doi. 10.1007/s11357-023-01011-0

By:

Harrison, David E.;
Strong, Randy;
Reifsnyder, Peter;
Rosenthal, Nadia;
Korstanje, Ron;
Fernandez, Elizabeth;
Flurkey, Kevin;
Ginsburg, Brett C.;
Murrell, Meredith D.;
Javors, Martin A.;
Lopez-Cruzan, Marisa;
Nelson, James F.;
Willcox, Bradley J.;
Allsopp, Richard;
Watumull, David M.;
Watumull, David G.;
Cortopassi, Gino;
Kirkland, James L.;
Tchkonia, Tamar;
Choi, Young Geun

Publication type:

Article

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex.

Published in:

Aging Cell, 2021, v. 20, n. 5, p. 1, doi. 10.1111/acel.13328

By:

Harrison, David E.;
Strong, Randy;
Reifsnyder, Peter;
Kumar, Navasuja;
Fernandez, Elizabeth;
Flurkey, Kevin;
Javors, Martin A.;
Lopez‐Cruzan, Marisa;
Macchiarini, Francesca;
Nelson, James F.;
Markewych, Adrian;
Bitto, Alessandro;
Sindler, Amy L.;
Cortopassi, Gino;
Kavanagh, Kylie;
Leng, Lin;
Bucala, Richard;
Rosenthal, Nadia;
Salmon, Adam;
Stearns, Timothy M.

Publication type:

Article

Shc depletion stimulates brown fat activity in vivo and in vitro.

Published in:

Aging Cell, 2014, v. 13, n. 6, p. 1049, doi. 10.1111/acel.12267

By:

Tomilov, Alexey;
Bettaieb, Ahmed;
Kim, Kyoungmi;
Sahdeo, Sunil;
Tomilova, Natalia;
Lam, Adam;
Hagopian, Kevork;
Connell, Michelle;
Fong, Jennifer;
Rowland, Douglas;
Griffey, Stephen;
Ramsey, Jon;
Haj, Fawaz;
Cortopassi, Gino

Publication type:

Article

The p66<sup>Shc</sup> knocked out mice are short lived under natural condition.

Published in:

Aging Cell, 2012, v. 11, n. 1, p. 162, doi. 10.1111/j.1474-9726.2011.00770.x

By:

Giorgio, Marco;
Berry, Alessandra;
Berniakovich, Ina;
Poletaeva, Inga;
Trinei, Mirella;
Stendardo, Massimo;
Hagopian, Kevork;
Ramsey, Jon J.;
Cortopassi, Gino;
Migliaccio, Enrica;
Nötzli, Sarah;
Amrein, Irmgard;
Lipp, Hans P.;
Cirulli, Francesca;
Pelicci, Pier G.

Publication type:

Article

The Shc locus regulates insulin signaling and adiposity in mammals.

Published in:

Aging Cell, 2011, v. 10, n. 1, p. 55, doi. 10.1111/j.1474-9726.2010.00641.x

By:

Tomilov, Alexey A.;
Ramsey, Jon J.;
Hagopian, Kevork;
Giorgio, Marco;
Kim, Kyoungmi M.;
Lam, Adam;
Migliaccio, Enrica;
Lloyd, Kent C.;
Berniakovich, Ina;
Prolla, Tomas A.;
Pelicci, PierGiuseppe;
Cortopassi, Gino A.

Publication type:

Article

Mitochondrial DNA deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins.

Published in:

Aging Cell, 2007, v. 6, n. 5, p. 619, doi. 10.1111/j.1474-9726.2007.00323.x

By:

Prigione, Alessandro;
Cortopassi, Gino

Publication type:

Article

Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich’s Ataxia.

Published in:

PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0217776

By:

Jasoliya, Mittal;
Sacca, Francesco;
Sahdeo, Sunil;
Chedin, Frederic;
Pane, Chiara;
Brescia Morra, Vincenzo;
Filla, Alessandro;
Pook, Mark;
Cortopassi, Gino

Publication type:

Article

In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride.

Published in:

Environmental Health Perspectives, 2017, v. 125, n. 8, p. 1, doi. 10.1289/EHP1404

By:

Datta, Sandipan;
Guochun He;
Tomilov, Alexey;
Sahdeo, Sunil;
Denison, Michael S.;
Cortopassi, Gino

Publication type:

Article

Sexual dimorphism in a mouse model of Friedreich's ataxia with severe cardiomyopathy.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06962-4

By:

Salinas, Lili;
Montgomery, Claire B.;
Figueroa, Francisco;
Thai, Phung N.;
Chiamvimonvat, Nipavan;
Cortopassi, Gino;
Dedkova, Elena N.

Publication type:

Article

Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer's mouse model and stimulates synaptic plasticity pathway enzymes.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-05860-z

By:

Di Lucente, Jacopo;
Persico, Giuseppe;
Zhou, Zeyu;
Jin, Lee-Way;
Ramsey, Jon J.;
Rutkowsky, Jennifer M.;
Montgomery, Claire M.;
Tomilov, Alexey;
Kim, Kyoungmi;
Giorgio, Marco;
Maezawa, Izumi;
Cortopassi, Gino A.

Publication type:

Article

Galectin-3 regulates inflammasome activation in cholestatic liver injury.

Published in:

FASEB Journal, 2016, v. 30, n. 12, p. 4202, doi. 10.1096/fj.201600392RR

By:

Jijing Tian;
Guoxiang Yang;
Huan-Yuan Chen;
Hsu, Daniel K.;
Tomilov, Alexey;
Olson, Kristin A.;
Dehnad, Ali;
Fish, Sarah R.;
Cortopassi, Gino;
Bin Zhao;
Fu-Tong Liu;
Gershwin, M. Eric;
Török, Natalie J.;
Jiang, Joy X.

Publication type:

Article

Mitochondrial inhibition induces PERK-dependent activation of the unfolded protein response stress pathway in human oligodendroglial cells.

Published in:

FASEB Journal, 2008, v. 22, p. 303, doi. 10.1096/fasebj.22.2_supplement.303

By:

Silva, Jillian M.;
Wong, Alice;
Cortopassi, Gino A.

Publication type:

Article

Multiple origins of a mitochondrial mutation conferring deafness.

Published in:

Genetics, 1997, v. 145, n. 3, p. 771, doi. 10.1093/genetics/145.3.771

By:

Hutchin, Timothy P.;
Cortopassi, Gino A.

Publication type:

Article

Key Glycolytic Enzyme Activities of Skeletal Muscle Are Decreased under Fed and Fasted States in Mice with Knocked Down Levels of Shc Proteins.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0124204

By:

Hagopian, Kevork;
Tomilov, Alexey A.;
Kim, Kyoungmi;
Cortopassi, Gino A.;
Ramsey, Jon J.

Publication type:

Article

Frequencies of hprt– mutations and bcl-2 translocations in circulating human lymphocytes are correlated with United Kingdom sunlight records.

Published in:

Mutagenesis, 1999, v. 14, n. 6, p. 527, doi. 10.1093/mutage/14.6.527

By:

Bentham, Graham;
Wolfreys, Alison M.;
Yafei Liu;
Cortopassi, Gino;
Green, Michael H. L.;
Arlett, Colin F.;
Cole, Jane

Publication type:

Article

Identification of the neuroprotective Shc target in Alzheimer's and validation of the neuroprotective benefit of a set of small‐molecule Shc blockers.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054369

By:

Tomilov, Alexey;
Maezawa, Izumi;
Jin, Lee‐Way;
Garcia, Chase;
Montgomery, Claire A;
Cortopassi, Gino A

Publication type:

Article

ApoE4 confers mitochondrial substrate oxidation defects that can be bioenergetically compensated by a ketogenic substrate beta‐hydroxy butyrate (BHB).

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054355

By:

Garcia, Chase;
Tomilov, Alexey;
Sandoval, Jose;
Cortopassi, Gino A

Publication type:

Article

Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 24, p. 4929, doi. 10.1093/hmg/ddx373

By:

Yu, Alfred K.;
Datta, Sandipan;
McMackin, Marissa Z.;
Cortopassi, Gino A.

Publication type:

Article

Dimethyl fumarate mediates Nrf2-dependent mitochondrial biogenesis in mice and humans.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 15, p. 2864, doi. 10.1093/hmg/ddx167

By:

Hayashi, Genki;
Jasoliya, Mittal;
Sahdeo, Sunil;
Saccá, Francesco;
Pane, Chiara;
Filla, Alessandro;
Marsili, Angela;
Puorro, Giorgia;
Lanzillo, Roberta;
Morra, Vincenzo Brescia;
Cortopassi, Gino

Publication type:

Article

Frataxin deficiency impairs mitochondrial biogenesis in cells, mice and humans.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 14, p. 2627, doi. 10.1093/hmg/ddx141

By:

Jasoliya, Mittal J.;
McMackin, Marissa Z.;
Henderson, Chelsea K.;
Perlman, Susan L.;
Cortopassi, Gino A.

Publication type:

Article

Mitochondrial complex I deficiency leads to inflammation and retinal ganglion cell death in the Ndufs4 mouse.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 10, p. 2848, doi. 10.1093/hmg/ddv045

By:

Yu, Alfred K.;
Lanying Song;
Murray, Karl D.;
van der List, Deborah;
Chao Sun;
Yan Shen;
Zhengui Xia;
Cortopassi, Gino A.

Publication type:

Article

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 25, p. 6848, doi. 10.1093/hmg/ddu408

By:

Sahdeo, Sunil;
Scott, Brian D.;
McMackin, Marissa Z.;
Jasoliya, Mittal;
Brown, Brandon;
Wulff, Heike;
Perlman, Susan L.;
Pook, Mark A.;
Cortopassi, Gino A.

Publication type:

Article

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 25, p. 6838, doi. 10.1093/hmg/ddu407

By:

Hayashi, Genki;
Shen, Yan;
Pedersen, Theresa L.;
Newman, John W.;
Pook, Mark;
Cortopassi, Gino

Publication type:

Article

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu408

By:

Sahdeo, Sunil;
Scott, Brian D.;
McMackin, Marissa Z.;
Jasoliya, Mittal;
Brown, Brandon;
Wulff, Heike;
Perlman, Susan L.;
Pook, Mark A.;
Cortopassi, Gino A.

Publication type:

Article

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu407

By:

Hayashi, Genki;
Yan Shen;
Pedersen, Theresa L.;
Newman, John W.;
Pook, Mark;
Cortopassi, Gino

Publication type:

Article

Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 23, p. 5147, doi. 10.1093/hmg/dds365

By:

Song, Lanying;
Shan, Yuxi;
Lloyd, K.C. Kent;
Cortopassi, Gino A.

Publication type:

Article