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DOCK8 is essential for T-cell survival and the maintenance of CD8 <sup>+</sup> T-cell memory.
Published in:
European Journal of Immunology, 2011, v. 41, n. 12, p. 3423, doi. 10.1002/eji.201141759
By:
- Lambe, Teresa;
- Crawford, Greg;
- Johnson, Andy L.;
- Crockford, Tanya L.;
- Bouriez-Jones, Tiphaine;
- Smyth, Aisling M.;
- Pham, Trung H. M.;
- Zhang, Qian;
- Freeman, Alexandra F.;
- Cyster, Jason G.;
- Su, Helen C.;
- Cornall, Richard J.
Publication type:
Article
Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.
Published in:
2009
By:
- Nijnik, Anastasia;
- Dawson, Sara;
- Crockford, Tanya L.;
- Woodbine, Lisa;
- Visetnoi, Supawan;
- Bennett, Sophia;
- Jones, Margaret;
- Turner, Gareth D.;
- Jeggo, Penelope A.;
- Goodnow, Christopher C.;
- Cornall, Richard J.
Publication type:
journal article
Spontaneous B cell hyperactivity in autoimmune-prone MRL mice.
Published in:
International Immunology, 2006, v. 18, n. 7, p. 1127, doi. 10.1093/intimm/dxl047
By:
- Anastasia Nijnik;
- Helen Ferry;
- Graham Lewis;
- Eleni Rapsomaniki;
- Janson C. H. Leung;
- Angelika Daser;
- Teresa Lambe;
- Christopher C. Goodnow;
- Richard J. Cornall
Publication type:
Article
Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome.
Published in:
Journal of Pathology, 2014, v. 233, n. 1, p. 18, doi. 10.1002/path.4308
By:
- Bull, Katherine R;
- Mason, Thomas;
- Rimmer, Andrew J;
- Crockford, Tanya L;
- Silver, Karlee L;
- Bouriez‐Jones, Tiphaine;
- Hough, Tertius A;
- Chaudhry, Shirine;
- Roberts, Ian SD;
- Goodnow, Christopher C;
- Cornall, Richard J
Publication type:
Article
Mutations in TCF12, encoding a basic helix-loop-helix partner of TWIST1, are a frequent cause of coronal craniosynostosis.
Published in:
Nature Genetics, 2013, v. 45, n. 10, p. 1261, doi. 10.1038/ng1013-1261a
By:
- Sharma, Vikram P;
- Fenwick, Aimée L;
- Brockop, Mia S;
- McGowan, Simon J;
- Goos, Jacqueline A C;
- Hoogeboom, A Jeannette M;
- Brady, Angela F;
- Jeelani, Nu Owase;
- Lynch, Sally Ann;
- Mulliken, John B;
- Murray, Dylan J;
- Phipps, Julie M;
- Sweeney, Elizabeth;
- Tomkins, Susan E;
- Wilson, Louise C;
- Bennett, Sophia;
- Cornall, Richard J;
- Broxholme, John;
- Kanapin, Alexander;
- Johnson, David
Publication type:
Article
Mutations in TCF12, encoding a basic helix-loop-helix partner of TWIST1, are a frequent cause of coronal craniosynostosis.
Published in:
Nature Genetics, 2013, v. 45, n. 3, p. 304, doi. 10.1038/ng.2531
By:
- Sharma, Vikram P;
- Fenwick, Aimée L;
- Brockop, Mia S;
- McGowan, Simon J;
- Goos, Jacqueline A C;
- Hoogeboom, A Jeannette M;
- Brady, Angela F;
- Jeelani, Nu Owase;
- Lynch, Sally Ann;
- Mulliken, John B;
- Murray, Dylan J;
- Phipps, Julie M;
- Sweeney, Elizabeth;
- Tomkins, Susan E;
- Wilson, Louise C;
- Bennett, Sophia;
- Cornall, Richard J;
- Broxholme, John;
- Kanapin, Alexander;
- Johnson, David
Publication type:
Article
Commentary 7.
Published in:
Experimental Dermatology, 2008, v. 17, n. 2, p. 157, doi. 10.1111/j.1600-0625.2007.00666_12.x
By:
- Lambe, Teresa;
- Cornall, Richard J.
Publication type:
Article
Immune Checkpoints as Therapeutic Targets in Autoimmunity.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02306
By:
- Paluch, Christopher;
- Santos, Ana Mafalda;
- Anzilotti, Consuelo;
- Cornall, Richard J.;
- Davis, Simon J.
Publication type:
Article
Renal Transplant Immunosuppression Impairs Natural Killer Cell Function In Vitro and In Vivo.
Published in:
PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013294
By:
- Morteau, Olivier;
- Blundell, Samkeliso;
- Chakera, Aron;
- Bennett, Sophia;
- Christou, Charita M.;
- Mason, Philip D.;
- Cornall, Richard J.;
- O'Callaghan, Christopher A.
Publication type:
Article
DNA repair is limiting for haematopoietic stem cells during ageing.
Published in:
Nature, 2007, v. 447, n. 7145, p. 686, doi. 10.1038/nature05875
By:
- Nijnik, Anastasia;
- Woodbine, Lisa;
- Marchetti, Caterina;
- Dawson, Sara;
- Lambe, Teresa;
- Cong Liu;
- Rodrigues, Neil P.;
- Crockford, Tanya L.;
- Cabuy, Erik;
- Vindigni, Alessandro;
- Enver, Tariq;
- Bell, John I.;
- Slijepcevic, Predrag;
- Goodnow, Christopher C.;
- Jeggo, Penelope A.;
- Cornall, Richard J.
Publication type:
Article
Targeted delivery of autoantigen to dendritic cells prevents development of spontaneous uveitis.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1227633
By:
- Klaska, Izabela P.;
- Tian Yu;
- Fordyce, Rosie;
- Koju Kamoi;
- Cornall, Richard J.;
- Martin-Granados, Cristina;
- Kuffova, Lucia;
- Forrester, John V.
Publication type:
Article
Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.
Published in:
2010
By:
- Johnson, Andy L;
- Aravind, L;
- Shulzhenko, Natalia;
- Morgun, Andre;
- Choi, See-Young;
- Crockford, Tanya L;
- Lambe, Teresa;
- Domaschenz, Heather;
- Kucharska, Edyta M;
- Zheng, Lixin;
- Vinuesa, Carola G;
- Lenardo, Michael J;
- Goodnow, Christopher C;
- Cornall, Richard J;
- Schwartz, Ronald H
Publication type:
Correction Notice
Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.
Published in:
Nature Immunology, 2009, v. 10, n. 8, p. 831, doi. 10.1038/ni.1769
By:
- Johnson, Andy L.;
- Aravind, L.;
- Shulzhenko, Natalia;
- Morgun, Andre;
- See-Young Choi;
- Crockford, Tanya L.;
- Lambe, Teresa;
- Domaschenz, Heather;
- Kucharska, Edyta M.;
- Zheng, Lixin;
- Vinuesa, Carola G.;
- Lenardo, Michael J.;
- Goodnow, Christopher C.;
- Cornall, Richard J.;
- Schwartz, Ronald H.
Publication type:
Article
B cells require DOCK8 to elicit and integrate T cell help when antigen is limiting.
Published in:
Science Immunology, 2024, v. 9, n. 98, p. 1, doi. 10.1126/sciimmunol.add4874
By:
- Deobagkar-Lele, Mukta;
- Crawford, Greg;
- Crockford, Tanya L.;
- Back, Jennifer;
- Hodgson, Rose;
- Bhandari, Aneesha;
- Bull, Katherine R.;
- Cornall, Richard J.
Publication type:
Article
The essential role of DOCK8 in humoral immunity.
Published in:
Disease Markers, 2010, v. 29, n. 3-4, p. 141
By:
- Su, Helen C.;
- Randall, Katrina L.;
- Lambe, Teresa;
- Goodnow, Chris C.;
- Cornall, Richard J.
Publication type:
Article
Treatment With FoxP3+ Antigen-Experienced T Regulatory Cells Arrests Progressive Retinal Damage in a Spontaneous Model of Uveitis.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.02071
By:
- Liu, Yi-Hsia;
- Mölzer, Christine;
- Makinen, Kimmo;
- Kamoi, Koju;
- Corbett, Clare L. C.;
- Klaska, Izabela P.;
- Reid, Delyth M.;
- Wilson, Heather M.;
- Kuffová, Lucia;
- Cornall, Richard J.;
- Forrester, John V.
Publication type:
Article
Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status.
Published in:
Clinical Infectious Diseases, 2022, v. 74, n. 7, p. 1208, doi. 10.1093/cid/ciab608
By:
- Lumley, Sheila F;
- Rodger, Gillian;
- Constantinides, Bede;
- Sanderson, Nicholas;
- Chau, Kevin K;
- Street, Teresa L;
- O'Donnell, Denise;
- Howarth, Alison;
- Hatch, Stephanie B;
- Marsden, Brian D;
- Cox, Stuart;
- James, Tim;
- Warren, Fiona;
- Peck, Liam J;
- Ritter, Thomas G;
- Toledo, Zoe de;
- Warren, Laura;
- Axten, David;
- Cornall, Richard J;
- Jones, E Yvonne
Publication type:
Article
The Duration, Dynamics, and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Responses in Individual Healthcare Workers.
Published in:
Clinical Infectious Diseases, 2021, v. 73, n. 3, p. e699, doi. 10.1093/cid/ciab004
By:
- Lumley, Sheila F;
- Wei, Jia;
- O'Donnell, Denise;
- Stoesser, Nicole E;
- Matthews, Philippa C;
- Howarth, Alison;
- Hatch, Stephanie B;
- Marsden, Brian D;
- Cox, Stuart;
- James, Tim;
- Peck, Liam J;
- Ritter, Thomas G;
- Toledo, Zoe de;
- Cornall, Richard J;
- Jones, E Yvonne;
- Stuart, David I;
- Screaton, Gavin;
- Ebner, Daniel;
- Hoosdally, Sarah;
- Crook, Derrick W
Publication type:
Article
Tolerance and autoimmunity in the eye: a role for CD8 T cells in organ-specific autoimmunity in the retina.
Published in:
2003
By:
- Forrester, John V.;
- Cornall, Richard J.
Publication type:
Editorial
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity.
Published in:
Nature, 2005, v. 435, n. 7041, p. 452, doi. 10.1038/nature03555
By:
- Vinuesa, Carola G.;
- Cook, Matthew C.;
- Angelucci, Constanza;
- Athanasopoulos, Vicki;
- Lixin Rui;
- Hill, Kim M.;
- Yu, Di;
- Domaschenz, Heather;
- Whittle, Belinda;
- Lambe, Teresa;
- Roberts, Ian S.;
- Copley, Richard R.;
- Bell, John I.;
- Cornall, Richard J.;
- Goodnow, Christopher C.
Publication type:
Article
Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.
Published in:
2021
By:
- Eyre, David W.;
- Lumley, Sheila F.;
- O'Donnell, Denise;
- Stoesser, Nicole E.;
- Matthews, Philippa C.;
- Howarth, Alison;
- Hatch, Stephanie B.;
- Marsden, Brian D.;
- Cox, Stuart;
- James, Tim;
- Cornall, Richard J.;
- Stuart, David I.;
- Screaton, Gavin;
- Ebner, Daniel;
- Crook, Derrick W.;
- Conlon, Christopher P.;
- Jeffery, Katie;
- Walker, Timothy M.;
- Peto, Timothy E. A.
Publication type:
journal article
Unlocking the Bottleneck in Forward Genetics Using Whole-Genome Sequencing and Identity by Descent to Isolate Causative Mutations.
Published in:
PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003219
By:
- Bull, Katherine R.;
- Rimmer, Andrew J.;
- Siggs, Owen M.;
- Miosge, Lisa A.;
- Roots, Carla M.;
- Enders, Anselm;
- Bertram, Edward M.;
- Crockford, Tanya L.;
- Whittle, Belinda;
- Potter, Paul K.;
- Simon, Michelle M.;
- Mallon, Ann-Marie;
- Brown, Steve D. M.;
- Beutler, Bruce;
- Goodnow, Christopher C.;
- Lunter, Gerton;
- Cornall, Richard J.
Publication type:
Article
The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target.
Published in:
Clinical & Developmental Immunology, 2012, p. 1, doi. 10.1155/2012/948218
By:
- Chakera, Aron;
- Bennett, Sophia C.;
- Morteau, Olivier;
- Bowness, Paul;
- Luqmani, Raashid A.;
- Cornall, Richard J.
Publication type:
Article
The high-risk corneal regraft model: a justification for tissue matching in humans.
Published in:
Transplant International, 2013, v. 26, n. 4, p. 453, doi. 10.1111/tri.12055
By:
- Vitova, Andrea;
- Kuffová, Lucia;
- Klaska, Izabela P.;
- Holan, Vladimir;
- Cornall, Richard J.;
- Forrester, John V.
Publication type:
Article
Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis.
Published in:
PLoS Medicine, 2008, v. 5, n. 3, p. e54, doi. 10.1371/journal.pmed.0050054
By:
- Heazlewood, Chad K.;
- Cook, Matthew C.;
- Eri, Rajaraman;
- Price, Gareth R.;
- Tauro, Sharyn B.;
- Taupin, Douglas;
- Thornton, David J.;
- Png, Chin Wen;
- Crockford, Tanya L.;
- Cornall, Richard J.;
- Adams, Rachel;
- Kato, Masato;
- Nelms, Keats A.;
- Hong, Nancy A.;
- Florin, Timothy H. J.;
- Goodnow, Christopher C.;
- McGuckin, Michael A.
Publication type:
Article
NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04118-w
By:
- Hodgson, Rose;
- Xu, Xijin;
- Anzilotti, Consuelo;
- Deobagkar-Lele, Mukta;
- Crockford, Tanya L.;
- Kepple, Jessica D.;
- Cawthorne, Eleanor;
- Bhandari, Aneesha;
- Cebrian-Serrano, Alberto;
- Wilcock, Martin J.;
- Davies, Benjamin;
- Cornall, Richard J.;
- Bull, Katherine R.
Publication type:
Article
MyD88-dependent autoimmune disease in Lyn-deficient mice.
Published in:
European Journal of Immunology, 2007, v. 37, n. 10, p. 2734, doi. 10.1002/eji.200737293
By:
- Silver, Karlee L.;
- Crockford, Tanya L.;
- Bouriez-Jones, Tiphaine;
- Milling, Simon;
- Lambe, Teresa;
- Cornall, Richard J.
Publication type:
Article
Spontaneous class switching and B cell hyperactivity increase autoimmunity against intracellular self antigen in Lyn-deficient mice.
Published in:
European Journal of Immunology, 2006, v. 36, n. 11, p. 2920, doi. 10.1002/eji.200636462
By:
- Silver, Karlee;
- Bouriez-Jones, Tiphaine;
- Crockford, Tanya;
- Ferry, Helen;
- Tang, H. Lucy;
- Cyster, Jason G.;
- Cornall, Richard J.
Publication type:
Article
TLR4, TLR9 and MyD88 are not requiredfor the positive selection of autoreactive B cells intothe primary repertoire.
Published in:
European Journal of Immunology, 2006, v. 36, n. 6, p. 1404, doi. 10.1002/eji.200636019
By:
- Silver, Karlee;
- Ferry, Helen;
- Crockford, Tanya;
- Cornall, Richard J.
Publication type:
Article
Correction: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
Published in:
European Journal of Immunology, 2005, v. 35, n. 12, p. 3714, doi. 10.1002/eji.255590598
By:
- Ferry, Helen;
- Crockford, Tanya L.;
- Silver, Karlee;
- Rust, Nigel;
- Goodnow, Christopher C.;
- Cornall, Richard J.
Publication type:
Article
Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
Published in:
European Journal of Immunology, 2005, v. 35, n. 12, p. 3655, doi. 10.1002/eji.200535247
By:
- Ferry, Helen;
- Cockford, Tanya L.;
- Silver, Karlee;
- Rust, Nigel;
- Goodnow, Christopher C.;
- Cornall, Richard J.
Publication type:
Article
Intact B cell tolerance in the absence of the first component of the classical complement pathway.
Published in:
European Journal of Immunology, 2001, v. 31, n. 7, p. 2087, doi. 10.1002/1521-4141(200107)31:7<2087::AID-IMMU2087>3.0.CO;2-C
By:
- Cutler, Antony J.;
- Cornall, Richard J.;
- Ferry, Helen;
- Manderson, Anthony P.;
- Botto, Marina;
- Walport, Mark J.
Publication type:
Article

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