Found: 10
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Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds.
- Published in:
- Scientific Data, 2022, v. 9, n. 1, p. 1, doi. 10.1038/s41597-022-01825-1
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- Publication type:
- Article
Network integration and modelling of dynamic drug responses at multi-omics levels.
- Published in:
- Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01302-8
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- Publication type:
- Article
Using quantitative systems pharmacology to evaluate the drug efficacy of COX-2 and 5-LOX inhibitors in therapeutic situations.
- Published in:
- NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0062-3
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- Publication type:
- Article
Integration of genome-scale metabolic networks into whole-body PBPK models shows phenotype-specific cases of drug-induced metabolic perturbation.
- Published in:
- NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0048-1
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- Publication type:
- Article
A Model‐Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 5, p. 1293, doi. 10.1002/cpt.2406
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- Publication type:
- Article
Gene expression databases for physiologically based pharmacokinetic modeling of humans and animal species.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 3, p. 311, doi. 10.1002/psp4.12904
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- Publication type:
- Article
A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations.
- Published in:
- PLoS Computational Biology, 2017, v. 13, n. 2, p. 1, doi. 10.1371/journal.pcbi.1005280
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- Publication type:
- Article
A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity.
- Published in:
- 2018
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- Publication type:
- Letter
Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients.
- Published in:
- Archives of Toxicology, 2017, v. 91, n. 2, p. 865, doi. 10.1007/s00204-016-1723-x
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- Publication type:
- Article
A Physiology-Based Model of Human Bile Acid Metabolism for Predicting Bile Acid Tissue Levels After Drug Administration in Healthy Subjects and BRIC Type 2 Patients.
- Published in:
- Frontiers in Physiology, 2019, p. 1, doi. 10.3389/fphys.2019.01192
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- Publication type:
- Article