Works by Connor, James R.

Results: 135

Serum ferritin is elevated in amyotrophic lateral sclerosis patients.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2015, v. 16, n. 1/2, p. 102, doi. 10.3109/21678421.2014.984723

By:

Su, Xiaowei W.;
Clardy, Stacey L.;
Stephens, Helen E.;
Simmons, Zachary;
Connor, James R.

Publication type:

Article

Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults.

Published in:

Fluids & Barriers of the CNS, 2017, p. 1, doi. 10.1186/s12987-017-0058-1

By:

Patton, Stephanie M.;
Quan Wang;
Hulgan, Todd;
Connor, James R.;
Jia, Peilin;
Zhongming Zhao;
Letendre, Scott L.;
Ellis, Ronald J.;
Bush, William S.;
Samuels, David C.;
Franklin, Donald R.;
Kaur, Harpreet;
Iudicello, Jennifer;
Grant, Igor;
Kallianpur, Asha R.

Publication type:

Article

Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0198775

By:

Chiou, Brian;
Neal, Emma H.;
Bowman, Aaron B.;
Lippmann, Ethan S.;
Simpson, Ian A.;
Connor, James R.

Publication type:

Article

Adaptive endoplasmic reticulum stress alters cellular responses to the extracellular milieu.

Published in:

Journal of Neuroscience Research, 2015, v. 93, n. 5, p. 766, doi. 10.1002/jnr.23541

By:

Liu, Yiting;
Neely, Elizabeth;
Simmons, Zachary;
Connor, James R.

Publication type:

Article

Targeting IL-13Rα<sub>2</sub> for effective treatment of malignant peripheral nerve sheath tumors in mouse models.

Published in:

Journal of Neurosurgery, 2019, v. 131, n. 5, p. 1369, doi. 10.3171/2018.7.jns18284

By:

Mrowczynski, Oliver D.;
Payne, Russell A.;
Bourcier, Alexandre J.;
Mau, Christine Y.;
Slagle-Webb, Becky;
Shenoy, Ganesh;
Madhankumar, Achuthamangalam B.;
Abramson, Stephan B.;
Wolfe, Darren;
Harbaugh, Kimberly S.;
Rizk, Elias B.;
Connor, James R.

Publication type:

Article

Gamma Knife radiosurgery of saccular aneurysms in a rabbit model.

Published in:

Journal of Neurosurgery, 2018, v. 129, n. 6, p. 1530, doi. 10.3171/2017.6.JNS17722

By:

Meadowcroft, Mark D.;
Cooper, Timothy K.;
Rupprecht, Sebastian;
Wright, Thaddeus C.;
Neely, Elizabeth E.;
Ferenci, Michele;
Weimin Kang;
Yang, Qing X.;
Harbaugh, Robert E.;
Connor, James R.;
McInerney, James

Publication type:

Article

Regional Variation in the Levels of Transferrin in the CNS of Normal and Myelin-Deficient Rats.

Published in:

Journal of Neurochemistry, 1987, v. 49, n. 5, p. 1523, doi. 10.1111/j.1471-4159.1987.tb01023.x

By:

Connor, James R.;
Phillips, Terry M.;
Lakshman, M. R.;
Barron, Kevin D.;
Fine, Richard E.;
Csiza, Charles K.

Publication type:

Article

Uptake of H-ferritin by Glioblastoma stem cells and its impact on their invasion capacity.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 12, p. 9691, doi. 10.1007/s00432-023-04864-2

By:

Shesh, Bhavyata;
Slagle-Webb, Becky;
Shenoy, Ganesh;
Khristov, Vladimir;
Zacharia, Brad E.;
Connor, James R.

Publication type:

Article

Low plasma serotonin linked to higher nigral iron in Parkinson's disease.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03700-2

By:

Jellen, Leslie C.;
Lewis, Mechelle M.;
Du, Guangwei;
Wang, Xi;
Galvis, Martha L. Escobar;
Krzyzanowski, Stanislaw;
Capan, Colt D.;
Snyder, Amanda M.;
Connor, James. R.;
Kong, Lan;
Mailman, Richard B.;
Brundin, Patrik;
Brundin, Lena;
Huang, Xuemei

Publication type:

Article

HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00165

By:

Ali-Rahmani, Fatima;
Schengrund, Cara-Lynne;
Connor, James R.

Publication type:

Article

Comparative Evaluation of Nephrotoxicity and Management by Macrophages of Intravenous Pharmaceutical Iron Formulations.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125272

By:

Connor, James R.;
Zhang, Xuesheng;
Nixon, Anne M.;
Webb, Becky;
Perno, Joseph R.

Publication type:

Article

Characterization of a Novel Anti-Cancer Compound for Astrocytomas.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108166

By:

Lee, Sang Y.;
Slagle-Webb, Becky;
Rizk, Elias;
Patel, Akshal;
Miller, Patti A.;
Sung, Shen-Shu;
Connor, James R.

Publication type:

Article

C282Y-HFE Gene Variant Affects Cholesterol Metabolism in Human Neuroblastoma Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088724

By:

Ali-Rahmani, Fatima;
Huang, Michael A.;
Schengrund, C.-L.;
Connor, James R.;
Lee, Sang Y.

Publication type:

Article

Maturational and Aging Effects on Human Brain Apparent Transverse Relaxation.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031907

By:

Jianli Wang;
Shaffer, Michele L.;
Eslinger, Paul J.;
Xiaoyu Sun;
Weitekamp, Christopher W.;
Patel, Megha M.;
Dossick, Deborah;
Gill, David J.;
Connor, James R.;
Yang, Qing X.

Publication type:

Article

Cortical iron regulation and inflammatory response in Alzheimer’s disease and APPSWE/PS11E9 mice: a histological perspective.

Published in:

Frontiers in Neuroscience, 2015, p. 1, doi. 10.3389/fnins.2015.00255

By:

Meadowcroft, Mark D.;
Connor, James R.;
Yang, Qing X.

Publication type:

Article

Bone Structural and Mechanical Properties Are Affected by Hypotransferrinemia But Not by Iron Deficiency in Mice.

Published in:

Journal of Bone & Mineral Research, 2000, v. 15, n. 2, p. 271, doi. 10.1359/jbmr.2000.15.2.271

By:

Malecki, Elise A.;
Buhl, Kathleen M.;
Beard, John L.;
Jacobs, Christopher R.;
Connor, James R.;
Donahue, Henry J.

Publication type:

Article

Oral iron therapy: Current concepts and future prospects for improving efficacy and outcomes.

Published in:

British Journal of Haematology, 2024, v. 204, n. 3, p. 759, doi. 10.1111/bjh.19268

By:

Ebea‐Ugwuanyi, Pearl O.;
Vidyasagar, Sadasivan;
Connor, James R.;
Frazer, David M.;
Knutson, Mitchell D.;
Collins, James F.

Publication type:

Article

Do oligodendrocytes mediate iron regulation in the human brain?

Published in:

Annals of Neurology, 1989, v. 26, n. 1, p. 95, doi. 10.1002/ana.410260115

By:

Gerber, Megan R.;
Connor, James R.

Publication type:

Article

Proteomic analysis of CSF can identify iron deficient monkeys.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1117, doi. 10.1096/fasebj.21.6.a1117-b

By:

Geguchadze, Ramaz N.;
Lubach, Gabriele R.;
Coe, Christopher L.;
Connor, James R.

Publication type:

Article

O-glycosylation regulates H-ferritin transport into the nucleus.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A990, doi. 10.1096/fasebj.21.6.a990-a

By:

Geguchadze, Ramaz N.;
Surgaldze, Nodar M.;
Xuesheng Zhang;
Weston, Holly R.;
Connor, James R.

Publication type:

Article

Lymphocytes from patients with Restless Legs Syndrome reflect a protein profile of iron deficiency and hypoxia.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A923, doi. 10.1096/fasebj.21.6.a923

By:

Patton, Stephanie Miller;
Ponnuru, Padmavathi;
Xinsheng Wang;
Earley, Christopher J.;
Allen, Richard P.;
Connor, James R.

Publication type:

Article

Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE.

Published in:

FASEB Journal, 2007, v. 21, n. 2, p. 564, doi. 10.1096/fj.06-6397com

By:

Lee, Sang Y.;
Patton, Stephanie M.;
Henderson, Rebecca J.;
Connor, James R.

Publication type:

Article

The case for iron chelation and/or antioxidant therapy in Alzheimer's disease.

Published in:

Drug Development Research, 2002, v. 56, n. 3, p. 526, doi. 10.1002/ddr.10105

By:

Malecki, Elise A.;
Connor, James R.

Publication type:

Article

Homeostatic iron regulatory protein drives glioblastoma growth via tumor cell-intrinsic and sex-specific responses.

Published in:

Neuro-Oncology Advances, 2024, v. 6, n. 1, p. 1, doi. 10.1093/noajnl/vdad154

By:

Troike, Katie M;
Wang, Sabrina Z;
Silver, Daniel J;
Lee, Juyeun;
Mulkearns-Hubert, Erin E;
Hajdari, Nicole;
Ghosh, Prabar K;
Kay, Kristen E;
Beilis, Julia L;
Mitchell, Sofia E;
Bishop, Christopher W;
Hong, Ellen S;
Artomov, Mykyta;
Hubert, Christopher G;
Rajappa, Prajwal;
Connor, James R;
Fox, Paul L;
Kristensen, Bjarne W;
Lathia, Justin D

Publication type:

Article

Reduced Cerebral White Matter Integrity Assessed by DTI in Cognitively Normal H63D-HFE Polymorphism Carriers.

Published in:

2018

By:

Meadowcroft, Mark D.;
Wang, Jianli;
Purnell, Carson J.;
Eslinger, Paul J.;
Neely, Elizabeth B.;
Yang, Qing X.;
Connor, James R.

Publication type:

journal article

Brain iron uptake in hypotransferrinemic mice: Influence of systemic iron status.

Published in:

Journal of Neuroscience Research, 2005, v. 79, n. 1/2, p. 254, doi. 10.1002/jnr.20324

By:

John L. Beard;
Jason A. Wiesinger;
Nan Li;
James R. Connor

Publication type:

Article

Myelination and motor coordination are increased in transferrin transgenic mice.

Published in:

Journal of Neuroscience Research, 2003, v. 72, n. 5, p. 587, doi. 10.1002/jnr.10619

By:

Maria-Carla Saleh;
Araceli Espinosa de los Monteros;
Gonzalo A. de Arriba Zerpa;
Isabelle Fontaine;
Oriane Piaud;
Dragan Djordjijevic;
Nadine Baroukh;
Angel Luis Garcia Otin;
Esteban Ortiz;
Sandra Lewis;
Laurence Fiette;
Paolo Santambrogio;
Catherine Belzung;
James R. Connor;
Jean de Vellis;
Juana M. Pasquini;
Mario M. Zakin;
Bruno Baron;
Florian Guillou

Publication type:

Article

Changes in iron histochemistry after hypoxic-ischemic brain injury in the neonatal rat.

Published in:

Journal of Neuroscience Research, 1999, v. 56, n. 1, p. 60, doi. 10.1002/(SICI)1097-4547(19990401)56:1<60::AID-JNR8>3.0.CO;2-A

By:

Palmer, Charles;
Menzies, Sharon L.;
Roberts, Rebecca L.;
Pavlick, Geno;
Connor, James R.

Publication type:

Article

Evidence for non-transferrin-mediated uptake and release of iron and manganese in glial cell cultures from hypotransferrinemic mice.

Published in:

Journal of Neuroscience Research, 1998, v. 51, n. 4, p. 454, doi. 10.1002/(SICI)1097-4547(19980215)51:4<454::AID-JNR5>3.0.CO;2-B

By:

Takeda, Atsushi;
Devenyi, Attila;
Connor, James R.

Publication type:

Article

Profile of altered brain iron acquisition in restless legs syndrome.

Published in:

Brain: A Journal of Neurology, 2011, v. 134, n. 4, p. 959, doi. 10.1093/brain/awr012

By:

Connor, James R.;
Ponnuru, Padmavathi;
Wang, Xin-Sheng;
Patton, Stephanie M.;
Allen, Richard P.;
Earley, Christopher J.

Publication type:

Article

Altered dopaminergic profile in the putamen and substantia nigra in restless leg syndrome.

Published in:

Brain: A Journal of Neurology, 2009, v. 132, n. 9, p. 2403, doi. 10.1093/brain/awp125

By:

Connor, James R.;
Xin-Sheng Wang;
Allen, Richard P.;
Beard, John L.;
Wiesinger, Jason A.;
Felt, Barbara T.;
Earley, Christopher J.

Publication type:

Article

A diet-induced mouse model for glutaric aciduria type I.

Published in:

Brain: A Journal of Neurology, 2006, v. 129, n. 4, p. 899, doi. 10.1093/brain/awl009

By:

William J. Zinnanti;
Jelena Lazovic;
Ellen B. Wolpert;
David A. Antonetti;
Michael B. Smith;
James R. Connor;
Michael Woontner;
Stephen I. Goodman;
Keith C. Cheng

Publication type:

Article

Genetics to MRI‐DTI: HFE mutation delays AD white matter degeneration in ApoE4 carriers.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075814

By:

Pang, Ran;
Wang, Jianli;
Karunanayaka, Prasanna;
Kanekar, Sangam;
Beselia, Gela;
Kaneka, Samika;
Connor, James R;
Yang, Qing

Publication type:

Article

Genetics to MRI‐DTI: HFE mutation delays AD white matter degeneration in ApoE4 carriers.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081697

By:

Pang, Ran;
Wang, Jianli;
Karunanayaka, Prasanna;
Kanekar, Sangam;
Beselia, Gela;
Kaneka, Samika;
Connor, James R;
Yang, Qing

Publication type:

Article

Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.

Published in:

2007

By:

Zinnanti, William J.;
Lazovic, Jelena;
Housman, Cathy;
LaNoue, Kathryn;
O'Callaghan, James P.;
Simpson, Ian;
Woontner, Michael;
Goodman, Stephen I.;
Connor, James R.;
Jacobs, Russell E.;
Cheng, Keith C.

Publication type:

journal article

Upregulation of iron regulatory proteins and divalent metal transporter-1 isoforms in the rat hippocampus after kainate induced neuronal injury.

Published in:

Experimental Brain Research, 2006, v. 170, n. 3, p. 376, doi. 10.1007/s00221-005-0220-x

By:

En Huang;
Wei-Yi Ong;
Mei-Lin Go;
Connor, James R.

Publication type:

Article

HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A.

Published in:

International Journal of Cancer, 2011, v. 129, n. 9, p. 2104, doi. 10.1002/ijc.25888

By:

Lee, Sang Y.;
Liu, Siying;
Mitchell, Ryan M.;
Slagle-Webb, Becky;
Hong, Young-Soo;
Sheehan, Jonas M.;
Connor, James R.

Publication type:

Article

Dietary lipophilic iron alters amyloidogenesis and microglial morphology in Alzheimer's disease knock-in APP mice.

Published in:

Metallomics, 2018, v. 10, n. 3, p. 426, doi. 10.1039/c8mt00004b

By:

Peters, Douglas G.;
Pollack, Alexis N.;
Cheng, Keith C.;
Sun, Dongxiao;
Saido, Takaomi;
Haaf, Michael P.;
Yang, Qing X.;
Connor, James R.;
Meadowcroft, Mark D.

Publication type:

Article

Tumor targeted delivery of doxorubicin in malignant peripheral nerve sheath tumors.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0181529

By:

Madhankumar, A. B.;
Mrowczynski, Oliver D.;
Slagle-Webb, Becky;
Ravi, Vagisha;
Bourcier, Alexandre J.;
Payne, Russell;
Harbaugh, Kimberly S.;
Rizk, Elias;
Connor, James R.

Publication type:

Article

Analysis of single nucleotide variants of HFE gene and association to survival in The Cancer Genome Atlas GBM data.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0174778

By:

Lee, Sang Y.;
Zhu, Junjia;
Salzberg, Anna C.;
Zhang, Bo;
Liu, Dajiang J.;
Muscat, Joshua E.;
Langan, Sara T.;
Connor, James R.

Publication type:

Article

Brain Metal Distribution and Neuro-Inflammatory Profiles after Chronic Vanadium Administration and Withdrawal in Mice.

Published in:

Frontiers in Neuroanatomy, 2017, p. 1, doi. 10.3389/fnana.2017.00058

By:

Folarin, Oluwabusayo R.;
Snyder, Amanda M.;
Peters, Douglas G.;
Olopade, Funmilayo;
Connor, James R.;
Olopade, James O.

Publication type:

Article

Microscopic R2* mapping of reduced brain iron in the Belgrade rat.

Published in:

Annals of Neurology, 2002, v. 52, n. 1, p. 102, doi. 10.1002/ana.10216

By:

Zywicke, Holly A.;
Van Gelderen, Peter;
Connor, James R.;
Burdo, Joseph R.;
Garrick, Michael D.;
Dolan, Kevin G.;
Frank, Joseph A.;
Bulte, Jeff W. M.

Publication type:

Article

Iron regulation in the brain: Histochemical, biochemical, and molecular considerations.

Published in:

Annals of Neurology, 1992, v. 32, n. S1, p. S51, doi. 10.1002/ana.410320710

By:

Connor, James R.;
Benkovic, Stanley A.

Publication type:

Article

Magnetic resonance imaging of APP/PS1/Tau mice on gradated iron diets.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P29, doi. 10.1016/j.jalz.2015.06.049

By:

Meadowcroft, Mark D.;
Peters, Douglas G.;
Haaf, Michael P.;
Yang, Qing X.;
Connor, James R.

Publication type:

Article

Differential MRI relaxation in Alzheimer’s patients with mutant hfe and transferrin genotypes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P28, doi. 10.1016/j.jalz.2015.06.048

By:

Meadowcroft, Mark D.;
Peters, Douglas G.;
Purnell, Carson J.;
Wang, Jianli;
Eslinger, Paul J.;
Yang, Qing X.;
Connor, James R.

Publication type:

Article

Magnetic resonance imaging of APP/PS1/Tau mice on gradated iron diets.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P407, doi. 10.1016/j.jalz.2015.06.049

By:

Meadowcroft, Mark D.;
Peters, Douglas G.;
Haaf, Michael P.;
Yang, Qing X.;
Connor, James R.

Publication type:

Article

Differential MRI relaxation in Alzheimer’s patients with mutant hfe and transferrin genotypes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P528, doi. 10.1016/j.jalz.2015.06.659

By:

Meadowcroft, Mark D.;
Peters, Douglas G.;
Purnell, Carson J.;
Wang, Jianli;
Eslinger, Paul J.;
Yang, Qing X.;
Connor, James R.

Publication type:

Article

Influence of iron genes and gender on brain iron and cognition

Published in:

2009

By:

Bartzokis, George;
Lu, Po H.;
Tingus, Kathleen;
Tishler, Todd A.;
Peters, Douglas G.;
Richard, Aurore;
Mintz, Jim;
Villablanca, Pablo;
Finn, J. Paul;
Laub, Gerhard;
Connor, James R.

Publication type:

Abstract

Influence of iron genes and gender on brain iron and cognition

Published in:

2009

By:

Bartzokis, George;
Lu, Po H.;
Tingus, Kathleen;
Tishler, Todd A.;
Peters, Douglas G.;
Richard, Aurore;
Mintz, Jim;
Villablanca, Pablo;
Finn, J. Paul;
Laub, Gerhard;
Connor, James R.

Publication type:

Abstract

P2-173: Impact of an iron regulatory gene, HFE, on tau phosphorylation mechanisms

Published in:

2008

By:

Hall, Eric C.;
Lee, Sang Y.;
Connor, James R.

Publication type:

Abstract