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The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 4, p. 1, doi. 10.15252/emmm.202012433
By:
- Scaramuzza, Linda;
- De Rocco, Giuseppina;
- Desiato, Genni;
- Cobolli Gigli, Clementina;
- Chiacchiaretta, Martina;
- Mirabella, Filippo;
- Pozzi, Davide;
- De Simone, Marco;
- Conforti, Paola;
- Pagani, Massimiliano;
- Benfenati, Fabio;
- Cesca, Fabrizia;
- Bedogni, Francesco;
- Landsberger, Nicoletta
Publication type:
Article
Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice.
Published in:
EMBO Molecular Medicine, 2020, v. 12, n. 10, p. 1, doi. 10.15252/emmm.202012519
By:
- Birolini, Giulia;
- Valenza, Marta;
- Di Paolo, Eleonora;
- Vezzoli, Elena;
- Talpo, Francesca;
- Maniezzi, Claudia;
- Caccia, Claudio;
- Leoni, Valerio;
- Taroni, Franco;
- Bocchi, Vittoria D;
- Conforti, Paola;
- Sogne, Elisa;
- Petricca, Lara;
- Cariulo, Cristina;
- Verani, Margherita;
- Caricasole, Andrea;
- Falqui, Andrea;
- Biella, Gerardo;
- Cattaneo, Elena
Publication type:
Article
SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes.
Published in:
2021
By:
- Birolini, Giulia;
- Verlengia, Gianluca;
- Talpo, Francesca;
- Maniezzi, Claudia;
- Zentilin, Lorena;
- Giacca, Mauro;
- Conforti, Paola;
- Cordiglieri, Chiara;
- Caccia, Claudio;
- Leoni, Valerio;
- Taroni, Franco;
- Biella, Gerardo;
- Simonato, Michele;
- Cattaneo, Elena;
- Valenza, Marta
Publication type:
journal article
Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid Models.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13159, doi. 10.3390/ijms232113159
By:
- Magni, Manuela;
- Bossi, Beatrice;
- Conforti, Paola;
- Galimberti, Maura;
- Dezi, Fabio;
- Lischetti, Tiziana;
- He, Xiaoling;
- Barker, Roger A.;
- Zuccato, Chiara;
- Espuny-Camacho, Ira;
- Cattaneo, Elena
Publication type:
Article
REST Controls Self-Renewal and Tumorigenic Competence of Human Glioblastoma Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038486
By:
- Conti, Luciano;
- Crisafulli, Laura;
- Caldera, Valentina;
- Tortoreto, Monica;
- Brilli, Elisa;
- Conforti, Paola;
- Zunino, Franco;
- Magrassi, Lorenzo;
- Schiffer, Davide;
- Cattaneo, Elena
Publication type:
Article
Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 26, p. 6972, doi. 10.1523/JNEUROSCI.4278-06.2007
By:
- Zuccato, Chiara;
- Belyaev, Nikolai;
- Conforti, Paola;
- Ooi, Lezanne;
- Tartari, Marzia;
- Papadimou, Evangelia;
- MacDonald, Marcy;
- Fossale, Elisa;
- Zeitlin, Scott;
- Buckley, Noel;
- Cattaneo, Elena
Publication type:
Article
Repressor element-1 silencing transcription factor ( REST) is present in human control and Huntington's disease neurones.
Published in:
Neuropathology & Applied Neurobiology, 2014, v. 40, n. 7, p. 899, doi. 10.1111/nan.12137
By:
- Schiffer, Davide;
- Caldera, Valentina;
- Mellai, Marta;
- Conforti, Paola;
- Cattaneo, Elena;
- Zuccato, Chiara
Publication type:
Article
Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.
Published in:
2019
By:
- Vezzoli, Elena;
- Caron, Ilaria;
- Talpo, Francesca;
- Besusso, Dario;
- Conforti, Paola;
- Battaglia, Elisa;
- Sogne, Elisa;
- Falqui, Andrea;
- Petricca, Lara;
- Verani, Margherita;
- Martufi, Paola;
- Caricasole, Andrea;
- Bresciani, Alberto;
- Cecchetti, Ottavia;
- di Val Cervo, Pia Rivetti;
- Sancini, Giulio;
- Riess, Olaf;
- Nguyen, Hoa;
- Seipold, Lisa;
- Saftig, Paul
Publication type:
journal article
Systematic Assessment of BDNF and Its Receptor Levels in Human Cortices Affected by Huntington's Disease.
Published in:
Brain Pathology, 2008, v. 18, n. 2, p. 225, doi. 10.1111/j.1750-3639.2007.00111.x
By:
- Zuccato, Chiara;
- Marullo, Manuela;
- Conforti, Paola;
- MacDonald, Marcy E.;
- Tartari, Marzia;
- Cattaneo, Elena
Publication type:
Article
Binding of the repressor complex REST- mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models.
Published in:
Journal of Neurochemistry, 2013, v. 127, n. 1, p. 22, doi. 10.1111/jnc.12348
By:
- Conforti, Paola;
- Zuccato, Chiara;
- Gaudenzi, Germano;
- Ieraci, Alessandro;
- Camnasio, Stefano;
- Buckley, Noel J.;
- Mutti, Cesare;
- Cotelli, Franco;
- Contini, Alessandro;
- Cattaneo, Elena
Publication type:
Article
Rescue of gene expression by modified REST decoy oligonucleotides in a cellular model of Huntington's disease.
Published in:
Journal of Neurochemistry, 2011, v. 116, n. 3, p. 415, doi. 10.1111/j.1471-4159.2010.07122.x
By:
- Soldati, Chiara;
- Bithell, Angela;
- Conforti, Paola;
- Cattaneo, Elena;
- Buckley, Noel J.
Publication type:
Article
ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.
Published in:
Human Molecular Genetics, 2021, v. 30, n. 13, p. 1175, doi. 10.1093/hmg/ddab047
By:
- Cozzolino, Flora;
- Vezzoli, Elena;
- Cheroni, Cristina;
- Besusso, Dario;
- Conforti, Paola;
- Valenza, Marta;
- Iacobucci, Ilaria;
- Monaco, Vittoria;
- Birolini, Giulia;
- Bombaci, Mauro;
- Falqui, Andrea;
- Saftig, Paul;
- Rossi, Riccardo L;
- Monti, Maria;
- Cattaneo, Elena;
- Zuccato, Chiara
Publication type:
Article
Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50877-x
By:
- Galimberti, Maura;
- Nucera, Maria R.;
- Bocchi, Vittoria D.;
- Conforti, Paola;
- Vezzoli, Elena;
- Cereda, Matteo;
- Maffezzini, Camilla;
- Iennaco, Raffaele;
- Scolz, Andrea;
- Falqui, Andrea;
- Cordiglieri, Chiara;
- Cremona, Martina;
- Espuny-Camacho, Ira;
- Faedo, Andrea;
- Felsenfeld, Dan P.;
- Vogt, Thomas F.;
- Ranzani, Valeria;
- Zuccato, Chiara;
- Besusso, Dario;
- Cattaneo, Elena
Publication type:
Article
hESC-derived striatal progenitors grafted into a Huntington's disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum.
Published in:
Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03422-4
By:
- Schellino, Roberta;
- Besusso, Dario;
- Parolisi, Roberta;
- Gómez-González, Gabriela B.;
- Dallere, Sveva;
- Scaramuzza, Linda;
- Ribodino, Marta;
- Campus, Ilaria;
- Conforti, Paola;
- Parmar, Malin;
- Boido, Marina;
- Cattaneo, Elena;
- Buffo, Annalisa
Publication type:
Article

Found: 14