Works by Concha-Marambio, Luis

Results: 23

α-Synuclein Seed Amplification in CSF and Brain from Patients with Different Brain Distributions of Pathological α-Synuclein in the Context of Co-Pathology and Non-LBD Diagnoses.

Published in:

2022

By:

Arnold, Moriah R.;
Coughlin, David G.;
Brumbach, Barbara H.;
Smirnov, Denis S.;
Concha‐Marambio, Luis;
Farris, Carly M.;
Ma, Yihua;
Kim, Yongya;
Wilson, Edward N.;
Kaye, Jeffrey A.;
Hiniker, Annie;
Woltjer, Randy L.;
Galasko, Doug R.;
Quinn, Joseph F.;
Concha-Marambio, Luis

Publication type:

journal article

Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid.

Published in:

Nature Protocols, 2023, v. 18, n. 4, p. 1179, doi. 10.1038/s41596-022-00787-3

By:

Concha-Marambio, Luis;
Pritzkow, Sandra;
Shahnawaz, Mohammad;
Farris, Carly M.;
Soto, Claudio

Publication type:

Article

Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha‐Synuclein Disease.

Published in:

Annals of Neurology, 2025, v. 97, n. 4, p. 730, doi. 10.1002/ana.27158

By:

Brown, Ethan G.;
Chahine, Lana M.;
Siderowf, Andrew;
Gochanour, Caroline;
Kurth, Ryan;
Marshall, Micah J.;
Caspell‐Garcia, Chelsea;
Brumm, Michael C.;
Stanley, Craig E.;
Korell, Monica;
McMahon, Bridget;
Kuhl, Maggie;
Fabrizio, Kimberly;
Heathers, Laura;
Concha‐Marambio, Luis;
Soto, Claudio;
Chowdhury, Sohini;
Coffey, Christopher S.;
Foroud, Tatiana M.;
Simuni, Tanya

Publication type:

Article

Association between the Amplification Parameters of the α‐Synuclein Seed Amplification Assay and Clinical and Genetic Subtypes of Parkinson's Disease.

Published in:

Movement Disorders, 2025, v. 40, n. 2, p. 305, doi. 10.1002/mds.30085

By:

Grillo, Piergiorgio;
Concha‐Marambio, Luis;
Pisani, Antonio;
Riboldi, Giulietta Maria;
Kang, Un Jung

Publication type:

Article

Accurate Detection of α‐Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNovo Parkinson (DeNoPa) Cohort.

Published in:

Movement Disorders, 2023, v. 38, n. 4, p. 567, doi. 10.1002/mds.29329

By:

Concha‐Marambio, Luis;
Weber, Sandrina;
Farris, Carly M.;
Dakna, Mohammed;
Lang, Elisabeth;
Wicke, Tamara;
Ma, Yihua;
Starke, Maritta;
Ebentheuer, Jens;
Sixel‐Döring, Friederike;
Muntean, Maria‐Lucia;
Schade, Sebastian;
Trenkwalder, Claudia;
Soto, Claudio;
Mollenhauer, Brit

Publication type:

Article

Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression.

Published in:

Movement Disorders, 2021, v. 36, n. 10, p. 2444, doi. 10.1002/mds.28715

By:

Concha‐Marambio, Luis;
Farris, Carly M.;
Holguin, Bret;
Ma, Yihua;
Seibyl, John;
Russo, Marco J.;
Kang, Un J.;
Hutten, Samantha J.;
Merchant, Kalpana;
Shahnawaz, Mohammad;
Soto, Claudio

Publication type:

Article

Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00613-8

By:

Bellomo, Giovanni;
Paciotti, Silvia;
Concha-Marambio, Luis;
Rizzo, Domenico;
Wojdaƚa, Anna Lidia;
Chiasserini, Davide;
Gatticchi, Leonardo;
Cerofolini, Linda;
Giuntini, Stefano;
De Luca, Chiara Maria Giulia;
Ma, Yihua;
Farris, Carly M.;
Pieraccini, Giuseppe;
Bologna, Sara;
Filidei, Marta;
Ravera, Enrico;
Lelli, Moreno;
Moda, Fabio;
Fragai, Marco;
Parnetti, Lucilla

Publication type:

Article

Seed amplification assay results illustrate discrepancy in Parkinson's disease clinical diagnostic accuracy and error rates.

Published in:

Journal of Neurology, 2023, v. 270, n. 12, p. 5813, doi. 10.1007/s00415-023-11810-2

By:

Middleton, John Stephen;
Hovren, Hanna Lynn;
Kha, Nelson;
Medina, Manuel Joseph;
MacLeod, Karen Ruth;
Concha-Marambio, Luis;
Jensen, Kendal Jay

Publication type:

Article

Thermal adaptation of mesophilic and thermophilic FtsZ assembly by modulation of the critical concentration.

Published in:

PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0185707

By:

Concha-Marambio, Luis;
Maldonado, Paula;
Lagos, Rosalba;
Monasterio, Octavio;
Montecinos-Franjola, Felipe

Publication type:

Article

High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8

By:

Russo, Marco J.;
Orru, Christina D.;
Concha-Marambio, Luis;
Giaisi, Simone;
Groveman, Bradley R.;
Farris, Carly M.;
Holguin, Bret;
Hughson, Andrew G.;
LaFontant, David-Erick;
Caspell-Garcia, Chelsea;
Coffey, Christopher S.;
Mollon, Jennifer;
Hutten, Samantha J.;
Merchant, Kalpana;
Heym, Roland G.;
Soto, Claudio;
Caughey, Byron;
Kang, Un Jung

Publication type:

Article

Correction to: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.

Published in:

2021

By:

Russo, Marco J.;
Orru, Christina D.;
Concha-Marambio, Luis;
Giaisi, Simone;
Groveman, Bradley R.;
Farris, Carly M.;
Holguin, Bret;
Hughson, Andrew G.;
LaFontant, David-Erick;
Caspell-Garcia, Chelsea;
Cofey, Christopher S.;
Mollon, Jennifer;
Hutten, Samantha J.;
Merchant, Kalpana;
Heym, Roland G.;
Soto, Claudio;
Caughey, Byron;
Kang, Un Jung

Publication type:

Correction Notice

High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8

By:

Russo, Marco J.;
Orru, Christina D.;
Concha-Marambio, Luis;
Giaisi, Simone;
Groveman, Bradley R.;
Farris, Carly M.;
Holguin, Bret;
Hughson, Andrew G.;
LaFontant, David-Erick;
Caspell-Garcia, Chelsea;
Coffey, Christopher S.;
Mollon, Jennifer;
Hutten, Samantha J.;
Merchant, Kalpana;
Heym, Roland G.;
Soto, Claudio;
Caughey, Byron;
Kang, Un Jung

Publication type:

Article

Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease.

Published in:

Science Translational Medicine, 2016, v. 8, n. 370, p. 1, doi. 10.1126/scitranslmed.aaf6188

By:

Concha-Marambio, Luis;
Pritzkow, Sandra;
Moda, Fabio;
Tagliavini, Fabrizio;
Ironside, James W.;
Schulz, Paul E.;
Soto, Claudio

Publication type:

Article

P.32: The extent of protease resistance of misfolded prion protein is highly dependent on the salt concentration.

Published in:

Prion, 2014, v. 8, p. 38

By:

Concha-Marambio, Luis;
Diaz-Espinoza, Rodrigo;
Soto, Claudio

Publication type:

Article

The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo.

Published in:

Scientific Reports, 2017, p. 44723, doi. 10.1038/srep44723

By:

Park, Kyung-Won;
Eun Kim, Gyoung;
Morales, Rodrigo;
Moda, Fabio;
Moreno-Gonzalez, Ines;
Concha-Marambio, Luis;
Lee, Amy S.;
Hetz, Claudio;
Soto, Claudio

Publication type:

Article

Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo.

Published in:

Scientific Reports, 2016, p. 32338, doi. 10.1038/srep32338

By:

Urayama, Akihiko;
Concha-Marambio, Luis;
Khan, Uffaf;
Bravo-Alegria, Javiera;
Kharat, Vineetkumar;
Soto, Claudio

Publication type:

Article

Preclinical Detection of Prions in Blood of Nonhuman Primates Infected with Variant Creutzfeldt-Jakob Disease.

Published in:

2020

By:

Concha-Marambio, Luis;
Chacon, Marcelo A.;
Soto, Claudio

Publication type:

journal article

Recent US Case of Variant Creutzfeldt-Jakob Disease-Global Implications.

Published in:

2015

By:

Maheshwari, Atul;
Fischer, Michael;
Gambetti, Pierluigi;
Parker, Alicia;
Ram, Aarthi;
Soto, Claudio;
Concha-Marambio, Luis;
Cohen, Yvonne;
Belay, Ermias D;
Maddox, Ryan A;
Mead, Simon;
Goodman, Clay;
Kass, Joseph S;
Schonberger, Lawrence B;
Hussein, Haitham M

Publication type:

journal article

Recent US Case of Variant Creutzfeldt-Jakob Disease--Global Implications.

Published in:

2015

By:

Maheshwari, Atul;
Fischer, Michael;
Gambetti, Pierluigi;
Parker, Alicia;
Ram, Aarthi;
Soto, Claudio;
Concha-Marambio, Luis;
Cohen, Yvonne;
Belay, Ermias D.;
Maddox, Ryan A.;
Mead, Simon;
Goodman, Clay;
Kass, Joseph S.;
Schonberger, Lawrence B.;
Hussein, Haitham M.

Publication type:

Case Study

Association of CSF α‐synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 12, p. 8444, doi. 10.1002/alz.14276

By:

Tosun, Duygu;
Hausle, Zachary;
Thropp, Pamela;
Concha‐Marambio, Luis;
Lamoureux, Jennifer;
Lebovitz, Russ;
Shaw, Leslie M.;
Singleton, Andrew B.;
Weiner, Michael W.;
Blauwendraat, Cornelis

Publication type:

Article

Clinicopathological correlation of cerebrospinal fluid alpha‐synuclein seed amplification assay in a behavioral neurology autopsy cohort.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 5, p. 3334, doi. 10.1002/alz.13799

By:

Samudra, Niyatee;
Fischer, D. Luke;
Lenio, Steven;
Lario Lago, Argentina;
Ljubenkov, Peter A.;
Rojas, Julio C.;
Seeley, William W.;
Spina, Salvatore;
Staffaroni, Adam M.;
Tablante, Jonathan;
Wekselman, Fattin;
Lamoureux, Jennifer;
Concha‐Marambio, Luis;
Grinberg, Lea T.;
Boxer, Adam L.;
VandeVrede, Lawren

Publication type:

Article

Investigating alpha‐synuclein co‐pathology in Alzheimer's disease by means of cerebrospinal fluid alpha‐synuclein seed amplification assay.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2444, doi. 10.1002/alz.13658

By:

Bellomo, Giovanni;
Toja, Andrea;
Paolini Paoletti, Federico;
Ma, Yihua;
Farris, Carly M.;
Gaetani, Lorenzo;
Salvadori, Nicola;
Chiasserini, Davide;
Wojdaƚa, Anna Lidia;
Concha‐Marambio, Luis;
Parnetti, Lucilla

Publication type:

Article

High Agreement Across Laboratories Between Different Alpha‐Synuclein Seed Amplification Protocols.

Published in:

European Journal of Neurology, 2025, v. 32, n. 4, p. 1, doi. 10.1111/ene.70165

By:

Bräuer, Stefan;
Weber, Maximilian;
Deuschle, Christian;
Julia, Kühlwein;
Concha‐Marambio, Luis;
Bernhardt, Alexander M.;
Kadam, Vaibhavi;
Mengel, David;
Ruf, Wolfgang P.;
Kassubek, Jan;
Schniewind, Iñaki;
Kuhs, Sandra;
Rossi, Marcello;
Parchi, Piero;
Levin, Johannes;
Danzer, Karin M.;
Synofzik, Matthis;
Brockmann, Kathrin;
Falkenburger, Björn H.

Publication type:

Article