Works by Comets, Emmanuelle

Results: 49

Cerebral uptake of mefloquine enantiomers with and without the P-gp inhibitor elacridar (GF1210918) in mice.

Published in:

British Journal of Pharmacology, 2004, v. 141, n. 7, p. 1214, doi. 10.1038/sj.bjp.0705721

By:

de Lagerie, Sylvie Barraud;
Comets, Emmanuelle;
Gautrand, Céline;
Fernandez, Christine;
Auchere, Daniel;
Singlas, Eric;
Mentre, France;
Gimenez, François

Publication type:

Article

Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 6, p. 1593, doi. 10.1002/cpt.3466

By:

Hamdan, Alzahra;
Hendrickx, Niels;
Hooker, Andrew C.;
Chen, Xiaomei;
Comets, Emmanuelle;
Traschütz, Andreas;
Schüle, Rebecca;
Heussen, Nicole Maria;
Hilgers, Ralf‐Dieter;
Klockgether, Thomas;
Ryeznik, Yevgen;
Sverdlov, Oleksandr;
Mentré, France;
Synofzik, Matthis;
Karlsson, Mats O.

Publication type:

Article

Modelling the influence of MDR1 polymorphism on digoxin pharmacokinetic parameters.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 5, p. 437, doi. 10.1007/s00228-007-0269-5

By:

Comets, Emmanuelle;
Verstuyft, Céline;
Lavielle, Marc;
Jaillon, Patrice;
Becquemont, Laurent;
Mentré, France

Publication type:

Article

The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia.

Published in:

Pharmaceutics, 2021, v. 13, n. 5, p. 601, doi. 10.3390/pharmaceutics13050601

By:

Michelet, Robin;
Ursino, Moreno;
Boulet, Sandrine;
Franck, Sebastian;
Casilag, Fiordiligie;
Baldry, Mara;
Rolff, Jens;
van Dyk, Madelé;
Wicha, Sebastian G.;
Sirard, Jean-Claude;
Comets, Emmanuelle;
Zohar, Sarah;
Kloft, Charlotte;
Sanjuán, Victor Mangas

Publication type:

Article

Conditional Non-parametric Bootstrap for Non-linear Mixed Effect Models.

Published in:

Pharmaceutical Research, 2021, v. 38, n. 6, p. 1057, doi. 10.1007/s11095-021-03052-6

By:

Comets, Emmanuelle;
Rodrigues, Christelle;
Jullien, Vincent;
Ursino, Moreno

Publication type:

Article

Population pharmacokinetic analysis of free and bound aflibercept in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 1, p. 167, doi. 10.1007/s00280-013-2182-1

By:

Thai, Hoai-Thu;
Veyrat-Follet, Christine;
Mentré, France;
Comets, Emmanuelle

Publication type:

Article

Pharmacokinetics and neutrophil toxicity of paclitaxel orally administered in mice with recombinant interleukin-2.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 55, n. 1, p. 61, doi. 10.1007/s00280-004-0824-z

By:

Jamois, Candice;
Comets, Emmanuelle;
Mentré, France;
Marion, Sylvie;
Farinotti, Robert;
Bonhomme-Faivre, Laurence

Publication type:

Article

A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed-effects models A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed-effects models.

Published in:

Pharmaceutical Statistics, 2013, v. 12, n. 3, p. 129, doi. 10.1002/pst.1561

By:

Thai, Hoai‐Thu;
Mentré, France;
Holford, Nicholas H.G.;
Veyrat‐Follet, Christine;
Comets, Emmanuelle

Publication type:

Article

Impact of model misspecification on model-based tests in PK studies with parallel design: real case and simulation studies.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 5, p. 557, doi. 10.1007/s10928-022-09821-z

By:

Guhl, Mélanie;
Mercier, François;
Hofmann, Carsten;
Sharan, Satish;
Donnelly, Mark;
Feng, Kairui;
Sun, Wanjie;
Sun, Guoying;
Grosser, Stella;
Zhao, Liang;
Fang, Lanyan;
Mentré, France;
Comets, Emmanuelle;
Bertrand, Julie

Publication type:

Article

Evaluation of bootstrap methods for estimating uncertainty of parameters in nonlinear mixed-effects models: a simulation study in population pharmacokinetics.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2014, v. 41, n. 1, p. 15, doi. 10.1007/s10928-013-9343-z

By:

Thai, Hoai-Thu;
Mentré, France;
Holford, Nicholas;
Veyrat-Follet, Christine;
Comets, Emmanuelle

Publication type:

Article

Extension of NPDE for evaluation of nonlinear mixed effect models in presence of data below the quantification limit with applications to HIV dynamic model.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2012, v. 39, n. 5, p. 499, doi. 10.1007/s10928-012-9264-2

By:

Nguyen, Thi;
Comets, Emmanuelle;
Mentré, France

Publication type:

Article

Pharmacogenetics and population pharmacokinetics: impact of the design on three tests using the SAEM algorithm.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2009, v. 36, n. 4, p. 317, doi. 10.1007/s10928-009-9124-x

By:

Julie Bertrand;
Emmanuelle Comets;
Céline Laffont;
Marylore Chenel;
France Mentré

Publication type:

Article

Therapeutic drug monitoring and virological response at week 48 in a cohort of HIV‐1‐infected patients switching to dolutegravir/rilpivirine dual maintenance therapy (ANRS‐MIE‐BIRIDER study).

Published in:

British Journal of Clinical Pharmacology, 2024, v. 90, n. 1, p. 264, doi. 10.1111/bcp.15890

By:

Lemaitre, Florian;
Lagoutte‐Renosi, Jennifer;
Gagnieu, Marie‐Claude;
Parant, François;
Venisse, Nicolas;
Grégoire, Matthieu;
Bouchet, Stéphane;
Garraffo, Rodolphe;
Lê, Minh P.;
Muret, Patrice;
Comets, Emmanuelle;
Solas, Caroline;
Peytavin, Gilles;
Chirouze, Catherine;
Hustache‐Mathieu, Laurent;
Gendrin, Vincent;
Drobatcheff‐Thiebaut, Marie‐Christine;
Foltzer, Adeline;
Obry‐Roguet, Véronique;
Brégigeon, Sylvie

Publication type:

Article

Population pharmacokinetics of oxcarbazepine and its monohydroxy derivative in epileptic children.

Published in:

British Journal of Clinical Pharmacology, 2017, v. 83, n. 12, p. 2695, doi. 10.1111/bcp.13392

By:

Rodrigues, Christelle;
Chiron, Catherine;
Rey, Elisabeth;
Dulac, Olivier;
Comets, Emmanuelle;
Pons, Gérard;
Jullien, Vincent

Publication type:

Article

Correction: Uncertainty Computation at Finite Distance in Nonlinear Mixed Effects Models—a New Method Based on Metropolis–Hastings Algorithm.

Published in:

2024

By:

Guhl, Mélanie;
Bertrand, Julie;
Fayette, Lucie;
Mercier, François;
Comets, Emmanuelle

Publication type:

Correction Notice

Correction: Prediction of Individual Disease Progression Including Parameter Uncertainty in Rare Neurodegenerative Diseases: The Example of Autosomal-Recessive Spastic Ataxia Charlevoix Saguenay (ARSACS).

Published in:

2024

By:

Hendrickx, Niels;
Mentré, France;
Traschütz, Andreas;
Gagnon, Cynthia;
Schüle, Rebecca;
Synofzik, Matthis;
Comets, Emmanuelle

Publication type:

Correction Notice

Uncertainty Computation at Finite Distance in Nonlinear Mixed Effects Models—a New Method Based on Metropolis-Hastings Algorithm.

Published in:

AAPS Journal, 2024, v. 26, n. 3, p. 1, doi. 10.1208/s12248-024-00905-x

By:

Guhl, Mélanie;
Bertrand, Julie;
Fayette, Lucie;
Mercier, François;
Comets, Emmanuelle

Publication type:

Article

Prediction of Individual Disease Progression Including Parameter Uncertainty in Rare Neurodegenerative Diseases: The Example of Autosomal-Recessive Spastic Ataxia Charlevoix Saguenay (ARSACS).

Published in:

AAPS Journal, 2024, v. 26, n. 3, p. 1, doi. 10.1208/s12248-024-00925-7

By:

Hendrickx, Niels;
Mentré, France;
Traschütz, Andreas;
Gagnon, Cynthia;
Schüle, Rebecca;
Synofzik, Matthis;
Comets, Emmanuelle

Publication type:

Article

Developing Tools to Evaluate Non-linear Mixed Effect Models: 20 Years on the npde Adventure.

Published in:

AAPS Journal, 2021, v. 23, n. 4, p. 1, doi. 10.1208/s12248-021-00597-7

By:

Comets, Emmanuelle;
Mentré, France

Publication type:

Article

Application of Item Response Theory to Model Disease Progression and Agomelatine Effect in Patients with Major Depressive Disorder.

Published in:

AAPS Journal, 2020, v. 22, n. 1, p. 1, doi. 10.1208/s12248-019-0379-x

By:

Cerou, Marc;
Peigné, Sophie;
Comets, Emmanuelle;
Chenel, Marylore

Publication type:

Article

Population Pharmacokinetic-Pharmacodynamic Model of Oral Fludrocortisone and Intravenous Hydrocortisone in Healthy Volunteers.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 727, doi. 10.1208/s12248-016-0041-9

By:

Hamitouche, Noureddine;
Comets, Emmanuelle;
Ribot, Mégane;
Alvarez, Jean-Claude;
Bellissant, Eric;
Laviolle, Bruno

Publication type:

Article

Joint Model of Iron and Hepcidin During the Menstrual Cycle in Healthy Women.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 490, doi. 10.1208/s12248-016-9875-4

By:

Angeli, Adeline;
Lainé, Fabrice;
Lavenu, Audrey;
Ropert, Martine;
Lacut, Karine;
Gissot, Valérie;
Sacher-Huvelin, Sylvie;
Jezequel, Caroline;
Moignet, Aline;
Laviolle, Bruno;
Comets, Emmanuelle

Publication type:

Article

Comparison of Nonlinear Mixed Effects Models and Noncompartmental Approaches in Detecting Pharmacogenetic Covariates.

Published in:

AAPS Journal, 2015, v. 17, n. 3, p. 597, doi. 10.1208/s12248-015-9726-8

By:

Tessier, Adrien;
Bertrand, Julie;
Chenel, Marylore;
Comets, Emmanuelle

Publication type:

Article

Development of a Complex Parent-Metabolite Joint Population Pharmacokinetic Model.

Published in:

AAPS Journal, 2011, v. 13, n. 3, p. 390, doi. 10.1208/s12248-011-9282-9

By:

Bertrand, Julie;
Laffont, Céline;
Mentré, France;
Chenel, Marylore;
Comets, Emmanuelle

Publication type:

Article

Multivariate Exact Discrepancy: A New Tool for PK/PD Model Evaluation.

Published in:

Clinical Pharmacokinetics, 2023, v. 62, n. 11, p. 1599, doi. 10.1007/s40262-023-01296-6

By:

Baklouti, Sarah;
Comets, Emmanuelle;
Gandia, Peggy;
Concordet, Didier

Publication type:

Article

A Survey of the Way Pharmacokinetics are Reported in Published Phase I Clinical Trials, with an Emphasis on Oncology.

Published in:

Clinical Pharmacokinetics, 2009, v. 48, n. 6, p. 387, doi. 10.2165/00003088-200948060-00004

By:

Comets, Emmanuelle;
Zohar, Sarah

Publication type:

Article

Are Population Pharmacokinetic and/or Pharmacodynamic Models Adequately Evaluated?: A Survey of the Literature from 2002 to 2004.

Published in:

Clinical Pharmacokinetics, 2007, v. 46, n. 3, p. 221, doi. 10.2165/00003088-200746030-00003

By:

Brendel, Karl;
Dartois, Céline;
Comets, Emmanuelle;
Lemenuel-Diot, Annabelle;
Laveille, Christian;
Tranchand, Brigitte;
Girard, Pascal;
Laffont, Céline M.;
Mentré, France

Publication type:

Article

A dose finding design for seizure reduction in neonates.

Published in:

Journal of the Royal Statistical Society: Series C (Applied Statistics), 2019, v. 68, n. 2, p. 427, doi. 10.1111/rssc.12289

By:

Ursino, Moreno;
Zohar, Sarah;
Yuan, Ying;
Alberti, Corinne;
Comets, Emmanuelle;
Favrais, Geraldine;
Friede, Tim;
Lentz, Frederike;
Stallard, Nigel

Publication type:

Article

Bayesian framework for multi-source data integration-Application to human extrapolation from preclinical studies.

Published in:

Statistical Methods in Medical Research, 2024, v. 33, n. 4, p. 574, doi. 10.1177/09622802241231493

By:

Boulet, Sandrine;
Ursino, Moreno;
Michelet, Robin;
Aulin, Linda BS;
Kloft, Charlotte;
Comets, Emmanuelle;
Zohar, Sarah

Publication type:

Article

Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies.

Published in:

2018

By:

Petit, Caroline;
Samson, Adeline;
Satoshi Morita;
Ursino, Moreno;
Guedj, Jérémie;
Jullien, Vincent;
Comets, Emmanuelle;
Zohar, Sarah;
Morita, Satoshi

Publication type:

journal article

Design in nonlinear mixed effects models: Optimization using the Fedorov-Wynn algorithm and power of the Wald test for binary covariates.

Published in:

Statistics in Medicine, 2007, v. 26, n. 28, p. 5162, doi. 10.1002/sim.2910

By:

Retout, Sylvie;
Comets, Emmanuelle;
Samson, Adeline;
Mentré, France

Publication type:

Article

Effects of Postpartum Supplemental Oral Ca for Dairy Cows Fed Prepartum Dietary Acidogenic Salts.

Published in:

Animals (2076-2615), 2021, v. 11, n. 11, p. 3131, doi. 10.3390/ani11113131

By:

Vagnoni, David B.;
Davidson, Michayla;
Rubio, Livia;
Oetzel, Garrett R.;
Comets, Emmanuelle

Publication type:

Article

Variations of hepcidin and iron-status parameters during the menstrual cycle in healthy women.

Published in:

British Journal of Haematology, 2016, v. 175, n. 5, p. 980, doi. 10.1111/bjh.13906

By:

Lainé, Fabrice;
Angeli, Adeline;
Ropert, Martine;
Jezequel, Caroline;
Bardou ‐ Jacquet, Edouard;
Deugnier, Yves;
Gissot, Valérie;
Lacut, Karine;
Sacher ‐ Huvelin, Sylvie;
Lavenu, Audrey;
Laviolle, Bruno;
Comets, Emmanuelle

Publication type:

Article

Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations.

Published in:

Biometrical Journal, 2017, v. 59, n. 4, p. 804, doi. 10.1002/bimj.201600084

By:

Ursino, Moreno;
Zohar, Sarah;
Lentz, Frederike;
Alberti, Corinne;
Friede, Tim;
Stallard, Nigel;
Comets, Emmanuelle

Publication type:

Article

Comparison of Model-Based Tests and Selection Strategies to Detect Genetic Polymorphisms Influencing Pharmacokinetic Parameters.

Published in:

Journal of Biopharmaceutical Statistics, 2008, v. 18, n. 6, p. 1084, doi. 10.1080/10543400802369012

By:

Bertrand, Julie;
Comets, Emmanuelle;
Mentré, France

Publication type:

Article

EVALUATION OF TESTS BASED ON INDIVIDUAL VERSUS POPULATION MODELING TO COMPARE DISSOLUTION CURVES.

Published in:

Journal of Biopharmaceutical Statistics, 2001, v. 11, n. 3, p. 107, doi. 10.1081/BIP-100107652

By:

Comets, Emmanuelle;
Mentré, France

Publication type:

Article

Design Optimization in Nonlinear Mixed Effects Models Using Cost Functions: Application to a Joint Model of Infliximab and Methotrexate Pharmacokinetics.

Published in:

Communications in Statistics: Theory & Methods, 2009, v. 38, n. 18, p. 3351, doi. 10.1080/03610920902833511

By:

Retout, Sylvie;
Comets, Emmanuelle;
Bazzoli, Caroline;
Mentré, France

Publication type:

Article

A mechanism-based model for the population pharmacokinetics of free and bound aflibercept in healthy subjects.

Published in:

British Journal of Clinical Pharmacology, 2011, v. 72, n. 3, p. 402, doi. 10.1111/j.1365-2125.2011.04015.x

By:

Hoai-Thu Thai;
Veyrat-Follet, Christine;
Vivier, Nicole;
Dubruc, Catherine;
Sanderink, Gerard;
Mentré, France;
Comets, Emmanuelle

Publication type:

Article

Some Alternatives to Asymptotic Tests for the Analysis of Pharmacogenetic Data Using Nonlinear Mixed Effects Models.

Published in:

Biometrics, 2012, v. 68, n. 1, p. 146, doi. 10.1111/j.1541-0420.2011.01665.x

By:

Bertrand, Julie;
Comets, Emmanuelle;
Chenel, Marylore;
Mentré, France

Publication type:

Article

Population pharmacodynamic analysis of octreotide in acromegalic patients<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 1, p. 95, doi. 10.1067/mcp.2003.6

By:

Comets, Emmanuelle;
Mentré, France;
Grass, Peter;
Kawai, Ryosei;
Marbach, Peter;
Vonderscher, Jacky

Publication type:

Article

Population pharmacokinetic-pharmacodynamic analysis of fluindione in patients<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 63, n. 1, p. 64, doi. 10.1016/S0009-9236(98)90122-9

By:

Mentré, France;
Pousset, Françoise;
Comets, Emmanuelle;
Plaud, Benoît;
Diquet, Bertrand;
Montalescot, Gilles;
Ankri, Annick;
Mallet, Alain;
Lechat, Philippe

Publication type:

Article

Joint modeling of tumor dynamics and progression‐free survival in advanced breast cancer: Leveraging data from amcenestrant early phase I–II trials.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 6, p. 941, doi. 10.1002/psp4.13128

By:

Cerou, Marc;
Thai, Hoai‐Thu;
Deyme, Laure;
Fliscounakis‐Huynh, Sophie;
Comets, Emmanuelle;
Cohen, Patrick;
Cartot‐Cotton, Sylvaine;
Veyrat‐Follet, Christine

Publication type:

Article

Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 9, p. 509, doi. 10.1002/psp4.12543

By:

Gonçalves, Antonio;
Bertrand, Julie;
Ke, Ruian;
Comets, Emmanuelle;
Lamballerie, Xavier;
Malvy, Denis;
Pizzorno, Andrés;
Terrier, Olivier;
Rosa Calatrava, Manuel;
Mentré, France;
Smith, Patrick;
Perelson, Alan S.;
Guedj, Jérémie

Publication type:

Article

The Standard Output: A Tool‐Agnostic Modeling Storage Format.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 9, p. 543, doi. 10.1002/psp4.12339

By:

Terranova, Nadia;
Smith, Mike K.;
Nordgren, Rikard;
Comets, Emmanuelle;
Lavielle, Marc;
Harling, Kajsa;
Hooker, Andrew C.;
Sarr, Celine;
Mentré, France;
Yvon, Florent;
Swat, Maciej J.

Publication type:

Article

Model Description Language (MDL): A Standard for Modeling and Simulation.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2017, v. 6, n. 10, p. 647, doi. 10.1002/psp4.12222

By:

Smith, Mike K.;
Moodie, Stuart L.;
Bizzotto, Roberto;
Blaudez, Eric;
Borella, Elisa;
Carrara, Letizia;
Chan, Phylinda;
Chenel, Marylore;
Comets, Emmanuelle;
Gieschke, Ronald;
Harling, Kajsa;
Harnisch, Lutz;
Hartung, Niklas;
Hooker, Andrew C.;
Karlsson, Mats O.;
Kaye, Richard;
Kloft, Charlotte;
Kokash, Natallia;
Lavielle, Marc;
Lestini, Giulia

Publication type:

Article

Why Should Prediction Discrepancies Be Renamed Standardized Visual Predictive Check?

Published in:

2012

By:

Comets, Emmanuelle;
Brendel, Karl;
Mentré, France

Publication type:

Letter

Recent advances in methodology for clinical trials in small populations: the InSPiRe project.

Published in:

2018

By:

Friede, Tim;
Posch, Martin;
Zohar, Sarah;
Alberti, Corinne;
Benda, Norbert;
Comets, Emmanuelle;
Day, Simon;
Dmitrienko, Alex;
Graf, Alexandra;
Günhan, Burak Kürsad;
Hee, Siew Wan;
Lentz, Frederike;
Madan, Jason;
Miller, Frank;
Ondra, Thomas;
Pearce, Michael;
Röver, Christian;
Toumazi, Artemis;
Unkel, Steffen;
Ursino, Moreno

Publication type:

journal article

Pharmacokinetics and safety of daptomycin administered subcutaneously in healthy volunteers: a single-blinded randomized crossover trial.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 11, p. 3016, doi. 10.1093/jac/dkae324

By:

Maurille, Charles;
Baldolli, Aurélie;
Creveuil, Christian;
Parienti, Jean-Jacques;
Michon, Jocelyn;
Peyro-Saint-Paul, Laure;
Brucato, Sylvie;
Dargere, Sylvie;
Comets, Emmanuelle;
Verdier, Marie-Clémence;
Verdon, Renaud

Publication type:

Article

Ciprofloxacin population pharmacokinetics during long-term treatment of osteoarticular infections.

Published in:

2021

By:

Zahr, Noël;
Urien, Saik;
Aubry, Alexandra;
Chauvin, Charlotte;
Comets, Emmanuelle;
Llopis, Benoit;
Tissot, Nadine;
Noe, Gaëlle;
Fourniols, Eric;
Jaureguiberry, Stéphane;
Bleibtreu, Alexandre;
Funck-Brentano, Christian;
Hospital, the Centre de Référence pour le traitement des Infections Ostéo-Articulaires Complexes (CRIOAC) Pitié-Salpêtrière;
Centre de Référence pour le traitement des Infections Ostéo-Articulaires Complexes (CRIOAC) Pitié-Salpêtrière Hospital

Publication type:

journal article