Found: 43
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Chemotherapy-induced gut toxicity and pain: involvement of TLRs.
- Published in:
- 2016
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- Publication type:
- journal article
Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report.
- Published in:
- 2017
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- Publication type:
- journal article
Contribution of TLR4 to colorectal tumor microenvironment, etiology and prognosis.
- Published in:
- Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 7, p. 3009, doi. 10.1007/s00432-022-04199-4
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- Publication type:
- Article
Investigation of TLR4 Antagonists for Prevention of Intestinal Inflammation.
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- Inflammation, 2023, v. 46, n. 1, p. 103, doi. 10.1007/s10753-022-01714-0
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- Publication type:
- Article
Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines.
- Published in:
- 2019
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- Publication type:
- journal article
Predictive model for risk of severe gastrointestinal toxicity following chemotherapy using patient immune genetics and type of cancer: a pilot study.
- Published in:
- Supportive Care in Cancer, 2015, v. 23, n. 5, p. 1233, doi. 10.1007/s00520-014-2481-z
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- Publication type:
- Article
ABCB1 haplotype and OPRM1 118A . G genotype interaction in methadone maintenance treatment pharmacogenetics.
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- Pharmacogenomics & Personalized Medicine, 2012, v. 5, p. 53, doi. 10.2147/PGPM.S29272
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- Publication type:
- Article
Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis.
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- Pharmacogenomics & Personalized Medicine, 2009, v. 2, p. 9
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- Publication type:
- Article
Association of Innate Immune Single-Nucleotide Polymorphisms with the Electroencephalogram During Desflurane General Anaesthesia.
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- Journal of Molecular Neuroscience, 2014, v. 52, n. 4, p. 497, doi. 10.1007/s12031-013-0201-7
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- Publication type:
- Article
Site‐specific contribution of Toll‐like receptor 4 to intestinal homeostasis and inflammatory disease.
- Published in:
- Journal of Cellular Physiology, 2021, v. 236, n. 2, p. 877, doi. 10.1002/jcp.29976
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- Publication type:
- Article
Epithelial-Specific TLR4 Knockout Challenges Current Evidence of TLR4 Homeostatic Control of Gut Permeability.
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- Inflammatory Intestinal Diseases, 2021, v. 6, n. 4, p. 199, doi. 10.1159/000519200
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- Publication type:
- Article
Pharmacogenetics of Opioids.
- Published in:
- Clinical Pharmacology & Therapeutics, 2007, v. 81, n. 3, p. 429, doi. 10.1038/sj.clpt.6100095
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- Publication type:
- Article
ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2006, v. 80, n. 6, p. 682, doi. 10.1016/j.clpt.2006.09.011
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- Publication type:
- Article
Associations of Immune Genetic Variability with Gulf War Illness in 1990–1991 Gulf War Veterans from the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study.
- Published in:
- Brain Sciences (2076-3425), 2021, v. 11, n. 11, p. 1410, doi. 10.3390/brainsci11111410
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- Publication type:
- Article
Brain–Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and Deployment Profile of 1990–1991 Gulf War Veterans in the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 9, p. 1132, doi. 10.3390/brainsci11091132
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- Publication type:
- Article
No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation.
- Published in:
- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2019.01686
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- Publication type:
- Article
Tacrolimus dose, blood concentrations and acute nephrotoxicity, but not CYP3A5/ABCB1 genetics, are associated with allograft tacrolimus concentrations in renal transplant recipients.
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- British Journal of Clinical Pharmacology, 2021, v. 87, n. 10, p. 3901, doi. 10.1111/bcp.14806
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- Publication type:
- Article
The impact of liver transplant recipient and donor genetic variability on tacrolimus exposure and transplant outcome.
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- British Journal of Clinical Pharmacology, 2019, v. 85, n. 9, p. 2170, doi. 10.1111/bcp.14034
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- Publication type:
- Article
Relationship between allograft cyclosporin concentrations and P‐glycoprotein expression in the 1st month following renal transplantation.
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- British Journal of Clinical Pharmacology, 2019, v. 85, n. 5, p. 1015, doi. 10.1111/bcp.13880
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- Publication type:
- Article
Mycophenolic acid concentrations in peripheral blood mononuclear cells are associated with the incidence of rejection in renal transplant recipients.
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- British Journal of Clinical Pharmacology, 2018, v. 84, n. 10, p. 2433, doi. 10.1111/bcp.13704
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- Publication type:
- Article
CYP2B6* 6 allele and age substantially reduce steady-state ketamine clearance in chronic pain patients: impact on adverse effects.
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- British Journal of Clinical Pharmacology, 2015, v. 80, n. 2, p. 276, doi. 10.1111/bcp.12614
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- Publication type:
- Article
Inhibition of CYP2D6-mediated tramadol O-demethylation in methadone but not buprenorphine maintenance patients.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 74, n. 5, p. 835, doi. 10.1111/j.1365-2125.2012.04256.x
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- Publication type:
- Article
Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 73, n. 5, p. 786, doi. 10.1111/j.1365-2125.2011.04145.x
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- Publication type:
- Article
The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation N. A. Helsby et al. Cyclophosphamide activation by CYP2C19 and CYP2B6.
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- British Journal of Clinical Pharmacology, 2010, v. 70, n. 6, p. 844, doi. 10.1111/j.1365-2125.2010.03789.x
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- Publication type:
- Article
Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline.
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- British Journal of Clinical Pharmacology, 2008, v. 65, n. 3, p. 347, doi. 10.1111/j.1365-2125.2007.03015.x
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- Publication type:
- Article
The Association between the Gut Microbiome and Development and Progression of Cancer Treatment Adverse Effects.
- Published in:
- Cancers, 2023, v. 15, n. 17, p. 4301, doi. 10.3390/cancers15174301
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- Publication type:
- Article
NK1 tachykinin receptor antagonist treatment reduces cerebral edema and intracranial pressure in an ovine model of ischemic stroke.
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- Journal of Cerebral Blood Flow & Metabolism, 2024, v. 44, n. 10, p. 1759, doi. 10.1177/0271678X241241907
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- Publication type:
- Article
Diarrhea Induced by Small Molecule Tyrosine Kinase Inhibitors Compared With Chemotherapy: Potential Role of the Microbiome.
- Published in:
- Integrative Cancer Therapies, 2020, v. 19, p. 1, doi. 10.1177/1534735420928493
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- Publication type:
- Article
TGFβ2 and TβRII are valid molecular biomarkers for the antiproliferative effects of tamoxifen and tamoxifen metabolites in breast cancer cells.
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- Breast Cancer Research & Treatment, 2008, v. 107, n. 1, p. 15
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- Publication type:
- Article
Role of active metabolites in the use of opioids.
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- European Journal of Clinical Pharmacology, 2009, v. 65, n. 2, p. 121, doi. 10.1007/s00228-008-0570-y
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- Publication type:
- Article
Advanced statistics identification of participant and treatment predictors associated with severe adverse effects induced by fluoropyrimidine-based chemotherapy.
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- Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 6, p. 507, doi. 10.1007/s00280-023-04538-3
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- Publication type:
- Article
Effects of a novel toll-like receptor 4 antagonist IAXO-102 in a murine model of chemotherapy-induced gastrointestinal toxicity.
- Published in:
- 2022
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- Publication type:
- journal article
Intestinal toll-like receptor 4 knockout alters the functional capacity of the gut microbiome following irinotecan treatment.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2022, v. 89, n. 2, p. 275, doi. 10.1007/s00280-021-04382-3
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- Publication type:
- Article
Toll-like receptor/interleukin-1 domain innate immune signalling pathway genetic variants are candidate predictors for severe gastrointestinal toxicity risk following 5-fluorouracil-based chemotherapy.
- Published in:
- 2019
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- Publication type:
- journal article
The influence of CYP2D6 genotype on trough plasma perhexiline and cis-OH-perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemia.
- Published in:
- British Journal of Clinical Pharmacology, 2006, v. 61, n. 3, p. 321, doi. 10.1111/j.1365-2125.2005.02570.x
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- Publication type:
- Article
Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexiline.
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- British Journal of Clinical Pharmacology, 2004, v. 57, n. 4, p. 456, doi. 10.1046/j.1365-2125.2003.02033.x
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- Publication type:
- Article
CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes.
- Published in:
- British Journal of Clinical Pharmacology, 2004, v. 57, n. 3, p. 287, doi. 10.1046/j.1365-2125.2003.02002.x
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- Publication type:
- Article
Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity.
- Published in:
- British Journal of Clinical Pharmacology, 2004, v. 57, n. 1, p. 105, doi. 10.1046/j.1365-2125.2003.01970.x
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- Publication type:
- Article
The influence of CYP2B6 ,CYP2C9 andCYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver.
- Published in:
- British Journal of Clinical Pharmacology, 2002, v. 54, n. 2, p. 157, doi. 10.1046/j.1365-2125.2002.01614.x
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- Publication type:
- Article
The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity.
- Published in:
- International Journal of Cancer, 2019, v. 144, n. 10, p. 2365, doi. 10.1002/ijc.31836
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- Publication type:
- Article
Intestinal accumulation of silica particles in a rat model of dextran sulfate sodium-induced colitis.
- Published in:
- Annals of Gastroenterology, 2019, v. 32, n. 6, p. 584, doi. 10.20524/aog.2019.0411
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- Publication type:
- Article
Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice.
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- British Journal of Pharmacology, 2012, v. 165, n. 5, p. 1319, doi. 10.1111/j.1476-5381.2011.01572.x
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- Publication type:
- Article
CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose‐adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post‐Kidney Transplantation.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2018, v. 123, n. 3, p. 320, doi. 10.1111/bcpt.13016
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- Publication type:
- Article