Works by Cole, Gregory M.

Results: 20

Reduced phosphorylation of brain insulin receptor substrate and Akt proteins in apolipoprotein-E4 targeted replacement mice.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03754

By:

Qi-Rui Ong;
Chan, Elizabeth S.;
Mei-Li Lim;
Cole, Gregory M.;
Boon-Seng Wong

Publication type:

Article

The effects of mild traumatic brain injury induced by a low‐intensity blast exposure on phosphoproteome networks and cognitive function influenced by mutant tau overexpression.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.084781

By:

Gu, Zezong;
Jackson, Marcus;
Chen, Shanyan;
Nguyen, Thi Thao;
Siedhoff, Heather R.;
Balderrama, Ashley;
Zuckerman, Amitai;
Li, Runting;
Greenlief, C. Michael;
Cole, Gregory M;
Frautschy, Sally A.;
Cui, Jiankun

Publication type:

Article

Characterization of a Bioactive Peptide T14 in the Human and Rodent Substantia Nigra: Implications for Neurodegenerative Disease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13119, doi. 10.3390/ijms232113119

By:

Greenfield, Susan Adele;
Ferrati, Giovanni;
Coen, Clive W.;
Vadisiute, Auguste;
Molnár, Zoltan;
Garcia-Rates, Sara;
Frautschy, Sally;
Cole, Gregory M.

Publication type:

Article

Isolation of synaptic terminals from Alzheimer's disease cortex.

Published in:

Cytometry. Part A, 2012, v. 81A, n. 3, p. 248, doi. 10.1002/cyto.a.22009

By:

Sokolow, Sophie;
Henkins, Kristen M.;
Williams, Iris A.;
Vinters, Harry V.;
Schmid, Ingrid;
Cole, Gregory M.;
Gylys, Karen H.

Publication type:

Article

Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort.

Published in:

Dementia & Geriatric Cognitive Disorders, 2015, v. 39, n. 3/4, p. 154, doi. 10.1159/000368982

By:

Teng, Edmond;
Chow, Nicole;
Hwang, Kristy S.;
Thompson, Paul M.;
Gylys, Karen H.;
Cole, Gregory M.;
Jack Jr., Clifford R.;
Shaw, Leslie M.;
Trojanowski, John Q.;
Soares, Holly D.;
Weiner, Michael W.;
Apostolova, Liana G.

Publication type:

Article

Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-β protein into synaptic terminals.

Published in:

Journal of Neurochemistry, 2003, v. 84, n. 6, p. 1442, doi. 10.1046/j.1471-4159.2003.01643.x

By:

Gylys, Karen H.;
Fein, Jeffrey A.;
Tan, Aiko M.;
Cole, Gregory M.

Publication type:

Article

A novel PDHK inhibitor restored cognitive dysfunction and limited neurodegeneration without affecting amyloid pathology in 5xFAD mouse, a model of Alzheimer's disease.

Published in:

Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01552-2

By:

Sakimura, Katsuya;
Kawai, Takashi;
Nashida, Reiko;
Ishida, Yuji;
Harada, Kana;
Suzuki, Takashi;
Okuma, Chihiro;
Cole, Gregory M.

Publication type:

Article

A novel process driving Alzheimer's disease validated in a mousemodel: Therapeutic potential.

Published in:

Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2022, v. 8, n. 1, p. 1, doi. 10.1002/trc2.12274

By:

Greenfield, Susan A.;
Cole, Gregory M.;
Coen, Clive W.;
Frautschy, Sally;
Singh, Ram P.;
Mekkittikul, Marisa;
Garcia-Ratés, Sara;
Morrill, Paul;
Hollings, Owen;
Passmore, Matt;
Hasan, Sibah;
Carty, Nikisha;
Bison, Silvia;
Piccoli, Laura;
Carletti, Renzo;
Tacconi, Stephano;
Chalidou, Anna;
Pedercini, Matthew;
Kroecher, Tim;
Astner, Hubert

Publication type:

Article

The novel omega‐6 fatty acid docosapentaenoic acid positively modulates brain innate immune response for resolving neuroinflammation at early and late stages of humanized APOE‐based Alzheimer's disease models: Nonhuman/Target identification and validation studies: Inflammation and innate immunity

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044178

By:

Ma, Qiulan‐Ma;
Zhu, Chansheng;
Caoili, Kaitlin;
Frautschy, Sally A.;
Cole, Gregory M

Publication type:

Article

P4‐683: OMEGA‐6 FATTY ACIDS AS A NOVEL IMMUNOTHERAPEUTIC APPROACH FOR THE TREATMENT OF ALZHEIMER'S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1593, doi. 10.1016/j.jalz.2019.09.048

By:

Ma, Qiulan-Ma;
Zhu, Chansheng;
Teter, Bruce;
Denver, Paul;
Jones, Mychica;
Frautschy, Sally A.;
Cole, Gregory M.

Publication type:

Article

P3‐147: APOLIPOPROTEIN E ISOTYPE AND EXERCISE INTERACT IN THE EPIGENETIC REGULATION OF MICRORNA‐146A.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P987, doi. 10.1016/j.jalz.2019.06.3175

By:

Teter, Bruce;
Ladu, Mary Jo;
Verduzco, Ana;
Frautschy, Sally A.;
Cole, Gregory M.

Publication type:

Article

P2‐211: PHARMACOGENOMIC IMPACT OF APOE4 ON TRANSCIPTIONAL REGULATION OF MICROGLIA IN AD MODEL MICE: IMPLICATIONS FOR PREVENTION AND TREATMENT.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P658, doi. 10.1016/j.jalz.2019.06.2618

By:

Cole, Gregory M.;
Verduzco, Ana;
Pellegrini, Matteo A.;
Su, Yu-Chyuan;
Ladu, Mary Jo;
Frautschy, Sally A.;
Teter, Bruce

Publication type:

Article

O2‐04‐04: A NOVEL TRANSGENIC RAT MODEL FOR MIXED DEMENTIA.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P544, doi. 10.1016/j.jalz.2019.06.4472

By:

Frautschy, Sally A.;
Jones, Mychica;
Denver, Paul;
D'Adamio, Heather;
Hu, Shuxin;
Cole, Gregory M.

Publication type:

Article

DIETARY LINOLEIC ACID DIFFERENTIALLY INFLUENCES BRAIN FADS ACTIVITIES INCREASING AN N-6 METABOLITE THAT INHIBITS INFLAMMATION AND PROMOTES AMYLOID-β CLEARANCE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P982, doi. 10.1016/j.jalz.2017.06.1335

By:

Cole, Gregory M.;
Ma, Qiu-Lan;
Teter, Bruce;
Jones, Mychica;
Frautschy, Sally A.

Publication type:

Article

Increased expression of sodium-calcium exchanger 3 (NCX3) in amyloid-beta positive synaptosomes

Published in:

2009

By:

Sokolow, Sophie;
Headley, Alison J.;
Henkins, Kristen M.;
Miller, Carol A.;
Vinters, Harry V.;
Frautschy, Sally A.;
Cole, Gregory M.;
Gylys, Karen H.

Publication type:

Abstract

A 56kD SDS-stable peptide assembly is prominent among multiple oligomers in Alzheimer synapses

Published in:

2009

By:

Gylys, Karen H.;
Henkins, Kristen;
Rhoades, Chelsea;
Sokolow, Sophie;
Vinters, Harry V.;
Miller, Carol A.;
Cole, Gregory M.

Publication type:

Abstract

P2-300: In vivo quantification of neuronal loss and neuropathological deposition in Alzheimer’s disease with PET

Published in:

2006

By:

Barrio, Jorge R.;
Kepe, Vladimir;
Huang, Sung-Cheng;
Ercoli, Linda;
Siddarth, Prabha;
Cole, Gregory M.;
Satyamurthy, Nagichettiar;
Cummings, Jeffrey L.;
Phelps, Michael E.;
Small, Gary W.

Publication type:

Abstract

P2-300: In vivo quantification of neuronal loss and neuropathological deposition in Alzheimer’s disease with PET

Published in:

2006

By:

Barrio, Jorge R.;
Kepe, Vladimir;
Huang, Sung-Cheng;
Ercoli, Linda;
Siddarth, Prabha;
Cole, Gregory M.;
Satyamurthy, Nagichettiar;
Cummings, Jeffrey L.;
Phelps, Michael E.;
Small, Gary W.

Publication type:

Abstract

In vivo [F-18]FDDNP microPET imaging of brain B-amyloid in a transgenic rat model of Alzheimer’s disease

Published in:

2005

By:

Kepe, Vladimir;
Cole, Gregory M.;
Liu, Jie;
Flood, Dorothy G.;
Trusko, Stephen P.;
Satyamurthy, Nagichettiar;
Huang, Sung-Chen;
Small, Gary W.;
Phelps, Michael E.;
Barrio, Jorge R.

Publication type:

Abstract

Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice.

Published in:

Scientific Reports, 2015, p. 13842, doi. 10.1038/srep13842

By:

Chan, Elizabeth S;
Chen, Christopher;
Cole, Gregory M;
Wong, Boon-Seng

Publication type:

Article