Works matching AU Colabufo, Nicola Antonio

Results: 30

Guinea-pig ileum as ex vivo model useful to characterize ligands displaying Imidazoline I2 and Adrenergic alpha2 mixed activity: a preliminary study.

Published in:

Drugs & Therapy Studies, 2013, v. 3, n. 1, p. 1, doi. 10.4081/dts.2013.e1

By:

Contino, Marialessandra;
Carrieri, Antonio;
Berardi, Francesco;
Leopoldo, Marcello;
Perrone, Roberto;
Thomas, Russell;
Colabufo, Nicola Antonio

Publication type:

Article

An updated patent review on P-glycoprotein inhibitors (2011-2018).

Published in:

Expert Opinion on Therapeutic Patents, 2019, v. 29, n. 6, p. 455, doi. 10.1080/13543776.2019.1618273

By:

Leopoldo, Marcello;
Nardulli, Patrizia;
Contino, Marialessandra;
Leonetti, Francesco;
Luurtsema, Gert;
Colabufo, Nicola Antonio

Publication type:

Article

6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 974, doi. 10.1080/14756366.2020.1747449

By:

Braconi, Laura;
Bartolucci, Gianluca;
Contino, Marialessandra;
Chiaramonte, Niccolò;
Giampietro, Roberta;
Manetti, Dina;
Perrone, Maria Grazia;
Romanelli, Maria Novella;
Colabufo, Nicola Antonio;
Riganti, Chiara;
Dei, Silvia;
Teodori, Elisabetta

Publication type:

Article

Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine.

Published in:

Pharmacology Research & Perspectives, 2015, v. 3, n. 5, p. 1, doi. 10.1002/prp2.160

By:

Gualdani, Roberta;
Tadini ‐ Buoninsegni, Francesco;
Roselli, Mariagrazia;
Defrenza, Ivana;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Lentini, Giovanni

Publication type:

Article

Gut-Derived Uremic Toxins in CKD: An Improved Approach for the Evaluation of Serum Indoxyl Sulfate in Clinical Practice.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5142, doi. 10.3390/ijms24065142

By:

Caggiano, Gianvito;
Amodio, Loredana;
Stasi, Alessandra;
Colabufo, Nicola Antonio;
Colangiulo, Santina;
Pesce, Francesco;
Gesualdo, Loreto

Publication type:

Article

Antiproliferative and cytotoxic effects of some σ2 agonists and σ1 antagonists in tumour cell lines.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 370, n. 2, p. 106

By:

Colabufo, Nicola Antonio;
Berardi, Francesco;
Contino, Marialessandra;
Niso, Mauro;
Abate, Carmen;
Perrone, Roberto;
Tortorella, Vincenzo

Publication type:

Article

PB28, the Sigma-1 and Sigma-2 Receptors Modulator With Potent Anti–SARS-CoV-2 Activity: A Review About Its Pharmacological Properties and Structure Affinity Relationships.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.589810

By:

Abate, Carmen;
Niso, Mauro;
Abatematteo, Francesca Serena;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line.

Published in:

Molecular Cancer, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1476-4598-12-47

By:

Pagliarulo, Vincenzo;
Ancona, Patrizia;
Niso, Mauro;
Colabufo, Nicola Antonio;
Contino, Marialessandra;
Cormio, Luigi;
Azzariti, Amalia;
Pagliarulo, Arcangelo

Publication type:

Article

Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers.

Published in:

ChemMedChem, 2017, v. 12, n. 16, p. 1369, doi. 10.1002/cmdc.201700239

By:

Teodori, Elisabetta;
Dei, Silvia;
Bartolucci, Gianluca;
Perrone, Maria Grazia;
Manetti, Dina;
Romanelli, Maria Novella;
Contino, Marialessandra;
Colabufo, Nicola Antonio

Publication type:

Article

A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression.

Published in:

ChemMedChem, 2016, v. 11, n. 4, p. 374, doi. 10.1002/cmdc.201500538

By:

Guglielmo, Stefano;
Contino, Marialessandra;
Lazzarato, Loretta;
Perrone, Maria Grazia;
Blangetti, Marco;
Fruttero, Roberta;
Colabufo, Nicola Antonio

Publication type:

Article

11C- and 18F-Labeled Radioligands for P-Glycoprotein Imaging by Positron Emission Tomography.

Published in:

ChemMedChem, 2016, v. 11, n. 1, p. 108, doi. 10.1002/cmdc.201500420

By:

Cantore, Mariangela;
Benadiba, Marcel;
Elsinga, Philip H.;
Kwizera, Chantal;
Dierckx, Rudi A. J. O.;
Colabufo, Nicola Antonio;
Luurtsema, Gert

Publication type:

Article

Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity.

Published in:

ChemMedChem, 2015, v. 10, n. 8, p. 1339, doi. 10.1002/cmdc.201500143

By:

Teodori, Elisabetta;
Dei, Silvia;
Floriddia, Elisa;
Perrone, Maria Grazia;
Manetti, Dina;
Romanelli, Maria Novella;
Contino, Marialessandra;
Colabufo, Nicola Antonio

Publication type:

Article

PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD.

Published in:

ChemMedChem, 2014, v. 9, n. 1, p. 38, doi. 10.1002/cmdc.201300362

By:

Leopoldo, Marcello;
Contino, Marialessandra;
Berardi, Francesco;
Perrone, Roberto;
Colabufo, Nicola Antonio

Publication type:

Article

Inside Cover: Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity (ChemMedChem 12/2013).

Published in:

ChemMedChem, 2013, v. 8, n. 12, p. 1898, doi. 10.1002/cmdc.201390051

By:

Niso, Mauro;
Abate, Carmen;
Contino, Marialessandra;
Ferorelli, Savina;
Azzariti, Amalia;
Perrone, Roberto;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity.

Published in:

ChemMedChem, 2013, v. 8, n. 12, p. 2026, doi. 10.1002/cmdc.201300291

By:

Niso, Mauro;
Abate, Carmen;
Contino, Marialessandra;
Ferorelli, Savina;
Azzariti, Amalia;
Perrone, Roberto;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease.

Published in:

ChemMedChem, 2012, v. 7, n. 3, p. 391, doi. 10.1002/cmdc.201100469

By:

Contino, Marialessandra;
Cantore, Mariangela;
Capparelli, Elena;
Perrone, Maria Grazia;
Niso, Mauro;
Inglese, Carmela;
Berardi, Francesco;
Leopoldo, Marcello;
Perrone, Roberto;
Colabufo, Nicola Antonio

Publication type:

Article

Inside Cover: 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ8-Δ7 Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity (ChemMedChem 1/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 1, p. 2, doi. 10.1002/cmdc.201090062

By:

Abate, Carmen;
Niso, Mauro;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Ferorelli, Savina;
Perrone, Roberto;
Berardi, Francesco

Publication type:

Article

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ8-Δ7 Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity.

Published in:

ChemMedChem, 2011, v. 6, n. 1, p. 73, doi. 10.1002/cmdc.201000371

By:

Abate, Carmen;
Niso, Mauro;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Ferorelli, Savina;
Perrone, Roberto;
Berardi, Francesco

Publication type:

Article

Chiral Aryloxyalkylamines: Selective 5-HT1B/1D Activation and Analgesic Activity.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 696, doi. 10.1002/cmdc.200900530

By:

Carocci, Alessia;
Lentini, Giovanni;
Catalano, Alessia;
Cavalluzzi, Maria Maddalena;
Bruno, Claudio;
Muraglia, Marilena;
Colabufo, Nicola Antonio;
Galeotti, Nicoletta;
Corbo, Filomena;
Matucci, Rosanna;
Ghelardini, Carla;
Franchini, Carlo

Publication type:

Article

A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39662-w

By:

Abatematteo, Francesca Serena;
Delre, Pietro;
Mercurio, Ivan;
Rezelj, Veronica V.;
Siliqi, Dritan;
Beaucourt, Stephanie;
Lattanzi, Gianluca;
Colabufo, Nicola Antonio;
Leopoldo, Marcello;
Saviano, Michele;
Vignuzzi, Marco;
Mangiatordi, Giuseppe Felice;
Abate, Carmen

Publication type:

Article

Small and innovative molecules as new strategy to revert MDR.

Published in:

Frontiers in Oncology, 2014, v. 3, p. 1, doi. 10.3389/fonc.2014.00002

By:

Zinzi, Laura;
Capparelli, Elena;
Cantore, Mariangela;
Contino, Marialessandra;
Leopoldo, Marcello;
Colabufo, Nicola Antonio

Publication type:

Article

miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives.

Published in:

Molecules, 2014, v. 19, n. 5, p. 5611, doi. 10.3390/molecules19055611

By:

Gisel, Andreas;
Valvano, Mirna;
El Idrissi, Imane Ghafir;
Nardulli, Patrizia;
Azzariti, Amalia;
Carrieri, Antonio;
Contino, Marialessandra;
Colabufo, Nicola Antonio

Publication type:

Article

Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.

Published in:

Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 11, p. 1453

By:

Nicola Antonio Colabufo;
Francesco Berardi;
Marialessandra Contino;
Ferruccio Fazio;
Mario Matarrese;
Rosa Maria Moresco;
Mauro Niso;
Roberto Perrone;
Vincenzo Tortorella

Publication type:

Article

Herbal Medicines in Brazil: Pharmacokinetic Profile and Potential Herb-Drug Interactions.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00162

By:

Mazzari, A. L. D. A.;
Prieto, J. M.;
Antonio Colabufo, Marcello Leopoldo Nicola

Publication type:

Article

ABC transporters in CSCs membranes as a novel target for treating tumour relapse.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00163

By:

ZINZI, LAURA;
Contino, Marialessandra;
Cantore, Mariangela;
Capparelli, Elena;
Leopoldo, Marcello;
Colabufo, Nicola Antonio

Publication type:

Article

Overcoming Multidrug Resistance (MDR): Design, Biological Evaluation and Molecular Modelling Studies of 2,4‐Substituted Quinazoline Derivatives.

Published in:

ChemMedChem, 2022, v. 17, n. 12, p. 1, doi. 10.1002/cmdc.202200027

By:

Braconi, Laura;
Teodori, Elisabetta;
Contino, Marialessandra;
Riganti, Chiara;
Bartolucci, Gianluca;
Manetti, Dina;
Romanelli, Maria Novella;
Perrone, Maria Grazia;
Colabufo, Nicola Antonio;
Guglielmo, Stefano;
Dei, Silvia

Publication type:

Article

Corrigendum: Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.

Published in:

ChemMedChem, 2022, v. 17, n. 7, p. 1, doi. 10.1002/cmdc.202200131

By:

Milani, Gualtiero;
Cavalluzzi, Maria Maddalena;
Altamura, Concetta;
Santoro, Antonella;
Perrone, Mariagrazia;
Muraglia, Marilena;
Colabufo, Nicola Antonio;
Corbo, Filomena;
Casalino, Elisabetta;
Franchini, Carlo;
Pisano, Isabella;
Desaphy, Jean‐François;
Carrieri, Antonio;
Carocci, Alessia;
Lentini, Giovanni

Publication type:

Article

Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.

Published in:

ChemMedChem, 2021, v. 16, n. 23, p. 3588, doi. 10.1002/cmdc.202100496

By:

Milani, Gualtiero;
Cavalluzzi, Maria Maddalena;
Altamura, Concetta;
Santoro, Antonella;
Perrone, Mariagrazia;
Muraglia, Marilena;
Colabufo, Nicola Antonio;
Corbo, Filomena;
Casalino, Elisabetta;
Franchini, Carlo;
Pisano, Isabella;
Desaphy, Jean‐François;
Carrieri, Antonio;
Carocci, Alessia;
Lentini, Giovanni

Publication type:

Article

Dual Inhibitors of P-gp and Carbonic Anhydrase XII (hCA XII) against Tumor Multidrug Resistance with Piperazine Scaffold †.

Published in:

Molecules, 2024, v. 29, n. 14, p. 3290, doi. 10.3390/molecules29143290

By:

Braconi, Laura;
Riganti, Chiara;
Parenti, Astrid;
Cecchi, Marta;
Nocentini, Alessio;
Bartolucci, Gianluca;
Menicatti, Marta;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Manetti, Dina;
Romanelli, Maria Novella;
Supuran, Claudiu T.;
Teodori, Elisabetta

Publication type:

Article

Design, synthesis, biological evaluation, NMR and DFT studies of structurally simplified trimethoxy benzamides as selective P-glycoprotein inhibitors: the role of molecular flatness.

Published in:

Chemical Biology & Drug Design, 2016, v. 88, n. 6, p. 820, doi. 10.1111/cbdd.12811

By:

Stefanachi, Angela;
Mangiatordi, Giuseppe Felice;
Tardia, Piero;
Alberga, Domenico;
Leonetti, Francesco;
Niso, Mauro;
Colabufo, Nicola Antonio;
Adamo, Carlo;
Nicolotti, Orazio;
Cellamare, Saverio

Publication type:

Article

Works matching AU Colabufo, Nicola Antonio

Guinea-pig ileum as ex vivo model useful to characterize ligands displaying Imidazoline I<sub>2</sub> and Adrenergic alpha<sub>2</sub> mixed activity: a preliminary study.

An updated patent review on P-glycoprotein inhibitors (2011-2018).

6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers.

Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine.

Gut-Derived Uremic Toxins in CKD: An Improved Approach for the Evaluation of Serum Indoxyl Sulfate in Clinical Practice.

Antiproliferative and cytotoxic effects of some σ<sub>2</sub> agonists and σ<sub>1</sub> antagonists in tumour cell lines.

PB28, the Sigma-1 and Sigma-2 Receptors Modulator With Potent Anti–SARS-CoV-2 Activity: A Review About Its Pharmacological Properties and Structure Affinity Relationships.

The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line.

Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers.

A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression.

<sup>11</sup>C- and <sup>18</sup>F-Labeled Radioligands for P-Glycoprotein Imaging by Positron Emission Tomography.

Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity.

PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD.

Inside Cover: Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity (ChemMedChem 12/2013).

Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity.

A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease.

Inside Cover: 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ<sub>8</sub>-Δ<sub>7</sub> Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity (ChemMedChem 1/2011).

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ<sub>8</sub>-Δ<sub>7</sub> Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity.

Chiral Aryloxyalkylamines: Selective 5-HT<sub>1B/1D</sub> Activation and Analgesic Activity.

A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach.

Small and innovative molecules as new strategy to revert MDR.

miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives.

Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.

Herbal Medicines in Brazil: Pharmacokinetic Profile and Potential Herb-Drug Interactions.

ABC transporters in CSCs membranes as a novel target for treating tumour relapse.

Overcoming Multidrug Resistance (MDR): Design, Biological Evaluation and Molecular Modelling Studies of 2,4‐Substituted Quinazoline Derivatives.

Corrigendum: Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.

Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels.

Dual Inhibitors of P-gp and Carbonic Anhydrase XII (hCA XII) against Tumor Multidrug Resistance with Piperazine Scaffold †.

Design, synthesis, biological evaluation, NMR and DFT studies of structurally simplified trimethoxy benzamides as selective P-glycoprotein inhibitors: the role of molecular flatness.