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Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-74005-3
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- Publication type:
- Article
The immunoglobulin heavy chain super enhancer controls class switch recombination in developing B cells.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-57576-z
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- Publication type:
- Article
Attempts to evaluate locus suicide recombination and its potential role in B cell negative selection in the mouse.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1155906
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- Publication type:
- Article
Distinct B-Cell Specific Transcriptional Contexts of the BCL2 Oncogene Impact Pre-Malignant Development in Mouse Models.
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- Cancers, 2022, v. 14, n. 21, p. 5337, doi. 10.3390/cancers14215337
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- Publication type:
- Article
Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma.
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- Cancers, 2021, v. 13, n. 15, p. 3755, doi. 10.3390/cancers13153755
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- Publication type:
- Article
Characterization of human FCRL4-positive B cells.
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- PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179793
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- Article
B Cell Intrinsic Mechanisms Constraining IgE Memory.
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- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01277
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- Publication type:
- Article
Functional anatomy of the immunoglobulin heavy chain 3' super-enhancer needs not only core enhancer elements but also their unique DNA context.
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- Nucleic Acids Research, 2017, v. 45, n. 10, p. 5829, doi. 10.1093/nar/gkx203
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- Publication type:
- Article
BURKITT'S LYMPHOMA CELL LINES PRODUCING TRUNCATED P IMMUNOGLOBULIN HEAVY CHAINS LACKING PART OF THE VARIABLE REGION.
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- European Journal of Immunology, 1988, v. 18, n. 10, p. 1485, doi. 10.1002/eji.1830181003
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- Publication type:
- Article
Major histocompatibility complex restriction of tetanus toxoid-specific human T lymphocyte clones.
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- European Journal of Immunology, 1984, v. 14, n. 12, p. 1131, doi. 10.1002/eji.1830141213
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- Publication type:
- Article
Publisher Correction: An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence.
- Published in:
- 2019
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- Publication type:
- Correction Notice
An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13108-2
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- Publication type:
- Article
An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13108-2
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- Publication type:
- Article
Circulating free light chain measurement in the diagnosis, prognostic assessment and evaluation of response of AL amyloidosis: comparison of Freelite and N latex FLC assays.
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- Clinical Chemistry & Laboratory Medicine, 2017, v. 55, n. 11, p. 1734, doi. 10.1515/cclm-2016-1024
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- Article
Polymorphism of the human a1 immunoglobulin gene 3' enhancer hs1, 2 and its relation to gene expression.
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- Immunology, 2001, v. 103, n. 1, p. 35, doi. 10.1046/j.1365-2567.2001.01217.x
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- Publication type:
- Article
Roles of G4-DNA and G4-RNA in Class Switch Recombination and Additional Regulations in B-Lymphocytes.
- Published in:
- Molecules, 2023, v. 28, n. 3, p. 1159, doi. 10.3390/molecules28031159
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- Publication type:
- Article
Deregulated platelet‐activating factor levels and acetylhydrolase activity in patients with idiopathic IgA nephropathy.
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- Nephrology Dialysis Transplantation, 2000, v. 15, n. 9, p. 1344, doi. 10.1093/ndt/15.9.1344
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- Publication type:
- Article
B-cell receptor signal strength influences terminal differentiation.
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- European Journal of Immunology, 2013, v. 43, n. 3, p. 619, doi. 10.1002/eji.201242912
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- Publication type:
- Article
Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation.
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- European Journal of Immunology, 2011, v. 41, n. 12, p. 3632, doi. 10.1002/eji.201140865
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- Publication type:
- Article
The IgH 3′ regulatory region and its implication in lymphomagenesis.
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- European Journal of Immunology, 2010, v. 40, n. 12, p. 3306, doi. 10.1002/eji.201040778
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- Publication type:
- Article
Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect.
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- European Journal of Immunology, 2006, v. 36, n. 8, p. 2181, doi. 10.1002/eji.200535529
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- Publication type:
- Article
Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line.
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- European Journal of Immunology, 2004, v. 34, n. 6, p. 1637, doi. 10.1002/eji.200324741
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- Publication type:
- Article
Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.
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- European Journal of Immunology, 2003, v. 33, n. 8, p. 2108, doi. 10.1002/eji.200323969
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- Publication type:
- Article
Synergies between regulatory elements of the immunoglobulin heavy chain locus and its palindromic 3 ′ locus control region.
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- European Journal of Immunology, 1998, v. 28, n. 10, p. 3048, doi. 10.1002/(SICI)1521-4141(199810)28:10<3048::AID-IMMU3048>3.0.CO;2-V
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- Publication type:
- Article
Identification of a homolog of the Cα3′/ hs3 enhancer and of an allelic variant of the 3′IgH/ hs1,2 enhancer downstream the human immunoglobulin α1 gene.
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- European Journal of Immunology, 1997, v. 27, n. 11, p. 2981, doi. 10.1002/eji.1830271134
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- Publication type:
- Article
Exon skipping without splice site mutation accounting for abnormal immunoglobulin chains in nonsecretory human myeloma.
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- European Journal of Immunology, 1993, v. 23, n. 6, p. 1289, doi. 10.1002/eji.1830230615
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- Publication type:
- Article
A human myeloma IgA with a hybrid heavy chain resulting from putative somatic gene conversion.
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- European Journal of Immunology, 1993, v. 23, n. 2, p. 364, doi. 10.1002/eji.1830230210
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- Publication type:
- Article
Immunoglobulin light chain transcripts with altered V regions in Burkitt's lymphoma cell lines producing short μ chains.
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- European Journal of Immunology, 1990, v. 20, n. 9, p. 1905, doi. 10.1002/eji.1830200906
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- Publication type:
- Article
Nuclear factors, hs1,2 enhancer and IgA nephropathy.
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- Kidney International, 2003, v. 63, n. 2, p. 767, doi. 10.1046/j.1523-1755.2003.00789.x
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- Publication type:
- Article
Alleles of the α1 immunoglobulin gene 3' enhancer control evolution of IgA nephropathy toward renal failure.
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- Kidney International, 2000, v. 58, n. 3, p. 966, doi. 10.1046/j.1523-1755.2000.00253.x
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- Publication type:
- Article
Monoclonal immunoglobulin deposition disease (Randall type). Relationship with structural abnormalities of immunoglobulin chains.
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- Kidney International, 1994, v. 46, n. 4, p. 965, doi. 10.1038/ki.1994.355
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- Publication type:
- Article
Preclinical study of <sup>212</sup>Pb alpha-radioimmunotherapy targeting CD20 in non-Hodgkin lymphoma.
- Published in:
- 2021
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- Publication type:
- journal article
Impact of HIV-1 Vpr manipulation of the DNA repair enzyme UNG2 on B lymphocyte class switch recombination.
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- 2020
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- Publication type:
- journal article
Paraoxonase 1 192/55 Gene Polymorphisms in Alzheimer's Disease.
- Published in:
- Annals of the New York Academy of Sciences, 2002, v. 977, n. 1, p. 239, doi. 10.1111/j.1749-6632.2002.tb04821.x
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- Publication type:
- Article
Light chain myeloma plasma cells induce a strong cell-mediated immune response mainly directed against the monoclonal light chain determinants in a murine experimental model.
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- Cancer Immunology, Immunotherapy, 2002, v. 51, n. 4, p. 229, doi. 10.1007/s00262-002-0274-6
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- Publication type:
- Article
Long-range oncogenic activation of Igh–c-myc translocations by the Igh 3′ regulatory region.
- Published in:
- Nature, 2009, v. 462, n. 7274, p. 803, doi. 10.1038/nature08633
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- Article
Editorial: Germinal Centers in Lymphoid and Non-Lymphoid Tissues: Adaptive and Evolving Structures.
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- 2022
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- Publication type:
- Editorial
Anti-FcαRI Monoclonal Antibodies Resolve IgA Autoantibody-Mediated Disease.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.732977
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- Publication type:
- Article
Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.744573
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- Publication type:
- Article
UnAIDed Class Switching in Activated B-Cells Reveals Intrinsic Features of a Self-Cleaving IgH Locus.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.737427
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- Publication type:
- Article
Venoarterial extracorporeal membrane oxygenation induces early immune alterations.
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- 2021
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- Publication type:
- journal article
History of IgA Nephropathy Mouse Models.
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- Journal of Clinical Medicine, 2021, v. 10, n. 14, p. 3142, doi. 10.3390/jcm10143142
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- Publication type:
- Article
Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter‐balanced by a strong Th2 bias.
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- Clinical & Translational Immunology, 2021, v. 10, n. 6, p. 1, doi. 10.1002/cti2.1280
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- Publication type:
- Article
Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3' regulatory region.
- Published in:
- Nature Communications, 2016, v. 7, n. 2, p. 10730, doi. 10.1038/ncomms10730
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- Publication type:
- Article
Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.
- Published in:
- Nature Communications, 2015, v. 6, n. 7, p. 7613, doi. 10.1038/ncomms8613
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- Publication type:
- Article
Elucidation of IgH 3′ region regulatory role during class switch recombination via germline deletion.
- Published in:
- Nature Communications, 2015, v. 6, n. 5, p. 7084, doi. 10.1038/ncomms8084
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- Publication type:
- Article
Polyclonal IgG4 hypergammaglobulinemia associated with plasmacytic lymphadenopathy, anemia and nephropathy.
- Published in:
- Annals of Hematology, 2006, v. 85, n. 12, p. 833, doi. 10.1007/s00277-006-0158-5
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- Publication type:
- Article
Deletion of the α immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion.
- Published in:
- Immunology, 2012, v. 136, n. 1, p. 54, doi. 10.1111/j.1365-2567.2012.03557.x
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- Publication type:
- Article
IgH 3' regulatory region increases ectopic class switch recombination.
- Published in:
- PLoS Genetics, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.pgen.1009288
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- Publication type:
- Article
Follicular lymphoma regulatory T-cell origin and function.
- Published in:
- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1391404
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- Publication type:
- Article