Works matching AU Coetzee, Gerhard

Results: 70

The Five Dimensions of Parkinson's Disease Genetic Risk.

Published in:

Journal of Parkinson's Disease, 2018, v. 8, n. 1, p. 13, doi. 10.3233/JPD-171256

By:

Coetzee, Gerhard A.;
Pierce, Steven

Publication type:

Article

motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites.

Published in:

Bioinformatics, 2015, v. 31, n. 23, p. 3847, doi. 10.1093/bioinformatics/btv470

By:

Coetzee, Simon G.;
Coetzee, Gerhard A.;
Hazelett, Dennis J.

Publication type:

Article

Principles for the post-GWAS functional characterization of cancer risk loci.

Published in:

2011

By:

Freedman, Matthew L.;
Monteiro, Alvaro N. A.;
Gayther, Simon A.;
Coetzee, Gerhard A.;
Risch, Angela;
Plass, Christoph;
Casey, Graham;
De Biasi, Mariella;
Carlson, Chris;
Duggan, David;
James, Michael;
Liu, Pengyuan;
Tichelaar, Jay W.;
Vikis, Haris G.;
Ming You;
Mills, Ian G.

Publication type:

Opinion

Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types.

Published in:

Carcinogenesis, 2011, v. 32, n. 8, p. 1238, doi. 10.1093/carcin/bgr104

By:

Davis-Dao, Carol A.;
Siegmund, Kimberly D.;
Vandenberg, David J.;
Skinner, Eila C.;
Coetzee, Gerhard A.;
Thomas, Duncan C.;
Pike, Malcolm C.;
Cortessis, Victoria K.

Publication type:

Article

Hypertension, diuretics and antihypertensives in relation to bladder cancer.

Published in:

Carcinogenesis, 2010, v. 31, n. 11, p. 1964, doi. 10.1093/carcin/bgq173

By:

Xuejuan Jiang;
Castelao, J. Esteban;
Jian-Min Yuan;
Groshen, Susan;
Stern, Mariana C.;
Conti, David V.;
Cortessis, Victoria K.;
Coetzee, Gerhard A.;
Pike, Malcolm C.;
Gago-Dominguez, Manuela

Publication type:

Article

Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits.

Published in:

Epigenetics & Chromatin, 2016, v. 9, p. 1, doi. 10.1186/s13072-016-0102-4

By:

Suhn Kyong Rhie;
Yu Guo;
Yu Gyoung Tak;
Lijing Yao;
Hui Shen;
Coetzee, Gerhard A.;
Laird, Peter W.;
Farnham, Peggy J.

Publication type:

Article

Expression and Functional Role of Orphan Receptor GPR158 in Prostate Cancer Growth and Progression.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117758

By:

Patel, Nitin;
Itakura, Tatsuo;
Jeong, Shinwu;
Liao, Chun-Peng;
Roy-Burman, Pradip;
Zandi, Ebrahim;
Groshen, Susan;
Pinski, Jacek;
Coetzee, Gerhard A.;
Gross, Mitchell E.;
Fini, M. Elizabeth

Publication type:

Article

Comprehensive Functional Annotation of Seventy-One Breast Cancer Risk Loci

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063925

By:

Rhie, Suhn Kyong;
Coetzee, Simon G.;
Noushmehr, Houtan;
Yan, Chunli;
Kim, Jae Mun;
Haiman, Christopher A.;
Coetzee, Gerhard A.

Publication type:

Article

TPL2/COT/MAP3K8 (TPL2) Activation Promotes Androgen Depletion-Independent (ADI) Prostate Cancer Growth.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016205

By:

Jeong, Joseph H.;
Bhatia, Ayesha;
Toth, Zsolt;
Soohwan Oh;
Kyung-Soo Inn;
Chun-Peng Liao;
Roy-Burman, Pradip;
Melamed, Jonathan;
Coetzee, Gerhard A.;
Jung, Jae U.

Publication type:

Article

Genomic Androgen Receptor-Occupied Regions with Different Functions, Defined by Histone Acetylation, Coregulators and Transcriptional Capacity.

Published in:

PLoS ONE, 2008, v. 3, n. 11, p. 1, doi. 10.1371/journal.pone.0003645

By:

Li Jia;
Berman, Benjamin P.;
Jariwala, Unnati;
Xiting Yan;
Cogan, Jon P.;
Walters, Allison;
Ting Chen;
Buchanan, Grant;
Frenkel, Baruch;
Coetzee, Gerhard A.

Publication type:

Article

GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor.

Published in:

Biological Chemistry, 2005, v. 386, n. 1, p. 69, doi. 10.1515/BC.2005.009

By:

Shen, Howard C.;
Buchanan, Grant;
Butler, Lisa M.;
Prescott, Jennifer;
Henderson, Michael;
Tilley, Wayne D.;
Coetzee, Gerhard A.

Publication type:

Article

Familial Hypercholesterolaemia in South Africa.

Published in:

Biological Chemistry, 1987, v. 368, n. 2, p. 1233

By:

GEVERS, Wieland;
CASCIOLA, Livia A. F.;
FOURIE, Anne M.;
SANAN, David A.;
COETZEE, Gerhard A.;
VAN DER WESTHUYZEN, Deneys R.

Publication type:

Article

Androgen and anti‐androgen treatment modulates androgen receptor activity and DJ‐1 stabilityTiina Pitkänen‐Arsiola and J. Erin Tillman have contributed equally to this work.

Published in:

Prostate, 2006, v. 66, n. 11, p. 1177

By:

Tiina Pitkänen‐Arsiola;
J. Erin Tillman;
Guangyu Gu;
Jialing Yuan;
Richard L. Roberts;
Marcus Wantroba;
Gerhard A. Coetzee;
Michael S. Cookson;
Susan Kasper

Publication type:

Article

PC‐3 cells with enhanced androgen receptor signaling: A model for clonal selection in prostate cancer.

Published in:

Prostate, 2004, v. 60, n. 4, p. 352, doi. 10.1002/pros.20079

By:

Grant Buchanan;
Paul S. Craft;
Miao Yang;
Albert Cheong;
Jennifer Prescott;
Li Jia;
Gerhard A. Coetzee;
Wayne D. Tilley

Publication type:

Article

The enigma and implications of brain hemispheric asymmetry in neurodegenerative diseases.

Published in:

Brain Communications, 2021, v. 3, n. 3, p. 1, doi. 10.1093/braincomms/fcab211

By:

Lubben, Noah;
Ensink, Elizabeth;
Coetzee, Gerhard A.;
Labrie, Viviane

Publication type:

Article

The Parkinson's disease variant rs356182 regulates neuronal differentiation independently from alpha-synuclein.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 1, p. 1, doi. 10.1093/hmg/ddac161

By:

Prahl, Jordan D;
Pierce, Steven E;
Schans, Edwin J C van der;
Coetzee, Gerhard A;
Tyson, Trevor

Publication type:

Article

Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 13, p. 3595, doi. 10.1093/hmg/ddv101

By:

Coetzee, Simon G.;
Shen, Howard C.;
Hazelett, Dennis J.;
Lawrenson, Kate;
Kuchenbaecker, Karoline;
Tyrer, Jonathan;
Rhie, Suhn K.;
Levanon, Keren;
Karst, Alison;
Drapkin, Ronny;
Ramus, Susan J.;
Couch, Fergus J.;
Offit, Kenneth;
Chenevix-Trench, Georgia;
Monteiro, Alvaro N. A.;
Antoniou, Antonis;
Freedman, Matthew;
Coetzee, Gerhard A.;
Pharoah, Paul D. P.;
Noushmehr, Houtan

Publication type:

Article

Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 8, p. 2198, doi. 10.1093/hmg/ddt584

By:

Biancolella, Michela;
Fortini, Barbara K.;
Tring, Stephanie;
Plummer, Sarah J.;
Mendoza-Fandino, Gustavo A.;
Hartiala, Jaana;
Hitchler, Michael J.;
Yan, Chunli;
Schumacher, Fredrick R.;
Conti, David V.;
Edlund, Christopher K.;
Noushmehr, Houtan;
Coetzee, Simon G.;
Bresalier, Robert S.;
Ahnen, Dennis J.;
Barry, Elizabeth L.;
Berman, Benjamin P.;
Rice, Judd C.;
Coetzee, Gerhard A.;
Casey, Graham

Publication type:

Article

Location, location, (ChIP-)location! Mapping chromatin landscapes one immunoprecipitation at a time.

Published in:

Journal of Cellular Biochemistry, 2009, v. 107, n. 1, p. 1, doi. 10.1002/jcb.22133

By:

Berman, Benjamin P.;
Frenkel, Baruch;
Coetzee, Gerhard A.

Publication type:

Article

Prostate specific antigen gene regulation by androgen receptor.

Published in:

Journal of Cellular Biochemistry, 2004, v. 93, n. 2, p. 233, doi. 10.1002/jcb.20228

By:

Joshua Kim;
Gerhard A. Coetzee

Publication type:

Article

Genetic susceptibility to cancer from exogenous and endogenous exposures.

Published in:

Journal of Cellular Biochemistry, 1996, v. 63, p. 15, doi. 10.1002/(SICI)1097-4644(1996)25+<15::AID-JCB2>3.0.CO;2-5

By:

Feigelson, Heather Spencer;
Ross, Ronald K.;
Yu, Mimi C.;
Coetzee, Gerhard A.;
Reichardt, Juergen K.V.;
Henderson, Brian E.

Publication type:

Article

Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.

Published in:

Human Genetics, 2002, v. 111, n. 3, p. 299, doi. 10.1007/s00439-002-0779-2

By:

Trinh, Binh N.;
Ong, Choon-Nam;
Coetzee, Gerhard A.;
Yu, Mimi C.;
Laird, Peter W.

Publication type:

Article

Sex Steroid Hormones and Genetic Susceptibility to Breast and Prostate Cancer.

Published in:

Drug Metabolism Reviews, 1998, v. 30, n. 2, p. 421, doi. 10.3109/03602539808996320

By:

Feigelson, Heather Spencer;
Ross, Ronald K.;
Yu, Mimi C.;
Coetzee, Gerhard A.;
Reichardt, Juergen K. V.;
Henderson, Brian E.

Publication type:

Article

Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson's disease etiology.

Published in:

Scientific Reports, 2016, p. 30509, doi. 10.1038/srep30509

By:

Coetzee, Simon G.;
Pierce, Steven;
Brundin, Patrik;
Brundin, Lena;
Hazelett, Dennis J.;
Coetzee, Gerhard A.

Publication type:

Article

4C-seq revealed long-range interactions of a functional enhancer at the 8q24 prostate cancer risk locus.

Published in:

Scientific Reports, 2016, p. 22462, doi. 10.1038/srep22462

By:

Cai, Mingyang;
Kim, Sewoon;
Wang, Kai;
Farnham, Peggy J.;
Coetzee, Gerhard A.;
Lu, Wange

Publication type:

Article

Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamine length.

Published in:

Human Molecular Genetics, 2000, v. 9, n. 2, p. 267, doi. 10.1093/hmg/9.2.267

By:

Irvine, Ryan A.;
Ma, Han;
Yu, Mimi C.;
Ross, Ronald K.;
Stallcup, Michael R.;
Coetzee, Gerhard A.

Publication type:

Article

Sequence variation and size ranges of CAG repeats in the Machado-Joseph disease, spinocerebellar ataxia type 1 and androgen receptor genes.

Published in:

Human Molecular Genetics, 1995, v. 4, n. 9, p. 1585

By:

Rubinsztein, David C.;
Leggo, Jayne;
Coetzee, Gerhard A.;
Irvine, Ryan A.;
Buckley, Michael;
Ferguson-Smith, Malcolm A.

Publication type:

Article

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

Published in:

International Journal of Cancer, 2013, v. 133, n. 12, p. 2812, doi. 10.1002/ijc.28310

By:

Trotta, Andrew P.;
Need, Eleanor F.;
Selth, Luke A.;
Chopra, Samarth;
Pinnock, Carole B.;
Leach, Damien A.;
Coetzee, Gerhard A.;
Butler, Lisa M.;
Tilley, Wayne D.;
Buchanan, Grant

Publication type:

Article

Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes.

Published in:

PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0175882

By:

Pierce, Steven;
Coetzee, Gerhard A.

Publication type:

Article

Genetic Elements at the Alpha-Synuclein Locus.

Published in:

Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.889802

By:

Prahl, Jordan;
Coetzee, Gerhard A.

Publication type:

Article

Dynamic Nucleosome-Depleted Regions at Androgen Receptor Enhancers in the Absence of Ligand in Prostate Cancer Cells.

Published in:

Molecular & Cellular Biology, 2011, v. 31, n. 23, p. 4648, doi. 10.1128/MCB.05934-11

By:

Andreu-Vieyra, Claudia;
Lai, John;
Berman, Benjamin P.;
Frenkel, Baruch;
Li Jia;
Jones, Peter A.;
Coetzee, Gerhard A.

Publication type:

Article

Post-GWAS knowledge gap: the how, where, and when.

Published in:

NPJ Parkinson's Disease, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41531-020-00125-y

By:

Pierce, Steven E.;
Booms, Alix;
Prahl, Jordan;
van der Schans, Edwin J. C.;
Tyson, Trevor;
Coetzee, Gerhard A.

Publication type:

Article

Structural and functional consequences of glutamine tract variation in the androgen receptor.

Published in:

Human Molecular Genetics, 2004, v. 13, n. 16, p. 1677, doi. 10.1093/hmg/ddh181

By:

Buchanan, Grant;
Yang, Miao;
Cheong, Albert;
Harris, Jonathan M.;
Irvine, Ryan A.;
Lambert, Paul F.;
Moore, Nicole L.;
Raynor, Michael;
Neufing, Petra J.;
Coetzee, Gerhard A.;
Tilley, Wayne D.

Publication type:

Article

Functions of Intracellular Alpha-Synuclein in Microglia: Implications for Parkinson's Disease Risk.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.759571

By:

Booms, Alix;
Coetzee, Gerhard A.

Publication type:

Article

Reducing GWAS Complexity.

Published in:

Cell Cycle, 2016, v. 15, n. 1, p. 22, doi. 10.1080/15384101.2015.1120928

By:

Hazelett, Dennis J.;
Conti, David V.;
Han, Ying;
Al Olama, Ali Amin;
Easton, Doug;
Eeles, Rosalind A.;
Kote-Jarai, Zsofia;
Haiman, Christopher A.;
Coetzee, Gerhard A.

Publication type:

Article

A rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk.

Published in:

Cell Cycle, 2013, v. 12, n. 2, p. 379, doi. 10.4161/cc.23201

By:

Hazelett, Dennis J.;
Coetzee, Simon G.;
Coetzee, Gerhard A.

Publication type:

Article

Identification and functional annotation of GWAS risk SNPs.

Published in:

Cell Cycle, 2011, v. 10, n. 23, p. 3995, doi. 10.4161/cc.10.23.18237

By:

Noushmehr, Houtan;
Coetzee, Gerhard A.

Publication type:

Article

Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-331

By:

Suhn Kyong Rhie;
Hazelett, Dennis J.;
Coetzee, Simon G.;
Yan, Chunli;
Noushmehr, Houtan;
Coetzee, Gerhard A.

Publication type:

Article

Locus-Wide Chromatin Remodeling and Enhanced Androgen Receptor-Mediated Transcription in Recurrent Prostate Tumor Cells.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 19, p. 26, doi. 10.1128/MCB.00581-06

By:

Li Jia;
Shen, Howard C.;
Wantroba, Marcus;
Khalid, Omar;
Liang, Gangning;
Wang, Qingcai;
Gentzschein, Elisabet;
Pinski, Jacek K.;
Stanczyk, Frank Z.;
Jones, Peter A.;
Coetzee, Gerhard A.

Publication type:

Article

Regulation of adult bone turnover by sex steroids.

Published in:

Journal of Cellular Physiology, 2010, v. 224, n. 2, p. 305, doi. 10.1002/jcp.22159

By:

FRENKEL, BARUCH;
HONG, ALBERT;
BANIWAL, SANJEEV K.;
COETZEE, GERHARD A.;
OHLSSON, CLAES;
KHALID, OMAR;
GABET, YANKEL

Publication type:

Article

CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops.

Published in:

Genome Biology, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s13059-018-1531-0

By:

Guo, Yu;
Perez, Andrew A.;
Hazelett, Dennis J.;
Coetzee, Gerhard A.;
Rhie, Suhn Kyong;
Farnham, Peggy J.

Publication type:

Article

Does the racial-ethnic variation in prostate cancer risk have a hormonal basis?

Published in:

Cancer (0008543X), 1995, v. 75, n. S7, p. 1778, doi. 10.1002/1097-0142(19950401)75:7+<1778::AID-CNCR2820751605>3.0.CO;2-J

By:

Ross, Ronald K.;
Coetzee, Gerhard A.;
Reichardt, Juergen;
Skinner, Eila;
Henderson, Brian E.

Publication type:

Article

Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.

Published in:

Molecular Cancer, 2010, v. 9, p. 258, doi. 10.1186/1476-4598-9-258

By:

Baniwal, Sanjeev K.;
Khalid, Omar;
Gabet, Yankel;
Shah, Ruchir R.;
Purcell, Daniel J.;
Mav, Deepak;
Kohn-Gabet, Alice E.;
Yunfan Shi;
Coetzee, Gerhard A.;
Frenkel, Baruch

Publication type:

Article

Identification of novel androgen receptor target genes in prostate cancer.

Published in:

Molecular Cancer, 2007, v. 6, p. 39, doi. 10.1186/1476-4598-6-39

By:

Jariwala, Unnati;
Prescott, Jennifer;
Li Jia;
Barski, Artem;
Pregizer, Steve;
Cogan, Jon P.;
Arasheben, Armin;
Tilley, Wayne D.;
Scher, Howard I.;
Gerald, William L.;
Buchanan, Grant;
Coetzee, Gerhard A.;
Frenkel, Baruch

Publication type:

Article

Dynamic methylation of histone H3 at lysine 4 in transcriptional regulation by the androgen receptor.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 23, p. 6741, doi. 10.1093/nar/gkg909

By:

Kim, Joshua;
Jia, Li;
Tilley, Wayne D.;
Coetzee, Gerhard A.

Publication type:

Article

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.

Published in:

Genome Biology, 2012, v. 13, n. 10, p. 1, doi. 10.1186/gb-2012-13-10-R88

By:

Tewari, Alok K.;
Yardimci, Galip Gürkan;
Shibata, Yoichiro;
Sheffield, Nathan C.;
Lingyun Song;
Taylor, Barry S.;
Georgiev, Stoyan G.;
Coetzee, Gerhard A.;
Ohler, Uwe;
Furey, Terrence S.;
Crawford, Gregory E.;
Febbo, Phillip G.

Publication type:

Article

Polymorphic exonic CAG microsatellites in the gene amplified in breast cancer ( AIB1 gene).

Published in:

Clinical Genetics, 1998, v. 54, n. 1, p. 102, doi. 10.1111/j.1399-0004.1998.tb03704.x

By:

Shirazi, Sherin K;
Bober, Mary A;
Coetzee, Gerhard A

Publication type:

Article

Genetically engineered stem cell‐derived neurons can be rendered resistant to alpha‐synuclein aggregate pathology.

Published in:

European Journal of Neuroscience, 2019, v. 49, n. 3, p. 316, doi. 10.1111/ejn.14333

By:

Brundin, Patrik;
Coetzee, Gerhard A.

Publication type:

Article

Androgen receptor responsive enhancers are lanked by consistently-positioned H3-acetylated nucleosomes.

Published in:

Cell Cycle, 2010, v. 9, n. 11, p. 2249, doi. 10.4161/cc.9.11.11621

By:

Berman, Benjamin P.;
Frenkel, Baruch;
Coetzee, Gerhard A.;
Li Jia

Publication type:

Article

A systematic approach to understand the functional consequences of non-protein coding risk regions.

Published in:

Cell Cycle, 2010, v. 9, n. 2, p. 256, doi. 10.4161/cc.9.2.10419

By:

Coetzee, Gerhard A.;
Li Jia;
Frenkel, Baruch;
Henderson, Brian E.;
Tanay, Amos;
Haiman, Christopher A.;
Freedman, Matthew L.

Publication type:

Article