Works by Coen, Muireann

Results: 21

Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.

Published in:

Archives of Toxicology, 2016, v. 90, n. 12, p. 3073, doi. 10.1007/s00204-015-1655-x

By:

Kyriakides, Michael;
Maitre, Lea;
Stamper, Brendan;
Mohar, Isaac;
Kavanagh, Terrance;
Foster, John;
Wilson, Ian;
Holmes, Elaine;
Nelson, Sidney;
Coen, Muireann

Publication type:

Article

Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.71332

By:

Stratakis, Nikos;
Siskos, Alexandros P.;
Papadopoulou, Eleni;
Nguyen, Anh N.;
Zhao, Yinqi;
Margetaki, Katerina;
Lau, Chung-Ho E.;
Coen, Muireann;
Maitre, Lea;
Fernández-Barrés, Silvia;
Agier, Lydiane;
Andrusaityte, Sandra;
Basagaña, Xavier;
Brantsaeter, Anne Lise;
Casas, Maribel;
Fossati, Serena;
Grazuleviciene, Regina;
Heude, Barbara;
McEachan, Rosemary R. C.;
Meltzer, Helle Margrete

Publication type:

Article

The Human Early-Life Exposome (HELIX): Project Rationale and Design.

Published in:

Environmental Health Perspectives, 2014, v. 122, n. 6, p. 535, doi. 10.1289/ehp.1307204

By:

Vrijheid, Martine;
Slama, Rémy;
Robinson, Oliver;
Chatzi, Leda;
Coen, Muireann;
Hazel, Peter van den;
Thomsen, Cathrine;
Wright, John;
Athersuch, Toby J.;
Avellana, Narcis;
Basagana, Xavier;
Brochot, Celine;
Bucchini, Luca;
Bustamante, Mariona;
Carracedo, Angel;
Casas, Maribel;
Estivill, Xavier;
Fairley, Lesley;
Gent, Diana van;
Gonzalez, Juan R.

Publication type:

Article

Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment.

Published in:

Archives of Toxicology, 2022, v. 96, n. 2, p. 613, doi. 10.1007/s00204-021-03197-8

By:

Hamm, Gregory;
Maglennon, Gareth;
Williamson, Beth;
Macdonald, Ruth;
Doherty, Ann;
Jones, Stewart;
Harris, Jayne;
Blades, James;
Harmer, Alexander R.;
Barton, Peter;
Rawlins, Philip B.;
Smith, Paul;
Winter-Holt, Jon;
McMurray, Lindsay;
Johansson, Julia;
Fitzpatrick, Paul;
McCoull, William;
Coen, Muireann

Publication type:

Article

Proton Nuclear Magnetic Resonance--Based Metabonomics for Rapid Diagnosis of Meningitis and Ventriculitis.

Published in:

Clinical Infectious Diseases, 2005, v. 41, n. 11, p. 1582, doi. 10.1086/497836

By:

Coen, Muireann;
O'sullivan, Matthew;
Bubb, William A.;
Kuchel, Philip W.;
Sorrell, Tania

Publication type:

Article

Translation of metabolite profiling to infectious diseases.

Published in:

2010

By:

Coen, Muireann;
Holmes, Elaine

Publication type:

Abstract

Maternal urinary metabolic signatures of fetal growth and associated clinical and environmental factors in the INMA study.

Published in:

BMC Medicine, 2016, v. 14, p. 1, doi. 10.1186/s12916-016-0706-3

By:

Maitre, Léa;
Villanueva, Cristina M.;
Lewis, Matthew R.;
Ibarluzea, Jesús;
Santa-Marina, Loreto;
Vrijheid, Martine;
Sunyer, Jordi;
Coen, Muireann;
Toledano, Mireille B.

Publication type:

Article

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective.

Published in:

Toxicology Research, 2018, v. 7, n. 3, p. 347, doi. 10.1039/c7tx00340d

By:

Athersuch, Toby J.;
Antoine, Daniel J.;
Boobis, Alan R.;
Coen, Muireann;
Daly, Ann K.;
Possamai, Lucia;
Nicholson, Jeremy K.;
Wilson, Ian D.

Publication type:

Article

Global metabolic changes induced by plant-derived pyrrolizidine alkaloids following a human poisoning outbreak and in a mouse model.

Published in:

Toxicology Research, 2016, v. 5, n. 6, p. 1594, doi. 10.1039/c6tx00221h

By:

Robinson, Oliver;
Toledano, Mireille B.;
Sands, Caroline;
Beckonert, Olaf;
J. Want, Elizabeth;
Goldin, Rob;
Hauser, Michael L.;
Fenwick, Alan;
Thursz, Mark R.;
Coen, Muireann

Publication type:

Article

Proteolysis-targeting chimeras in drug development: A safety perspective.

Published in:

2020

By:

Moreau, Kevin;
Coen, Muireann;
Zhang, Andrew X.;
Pachl, Fiona;
Castaldi, M. Paola;
Dahl, Goran;
Boyd, Helen;
Scott, Clay;
Newham, Pete

Publication type:

journal article

Assessment of metabolic phenotypic variability in children's urine using <sup>1</sup>H NMR spectroscopy.

Published in:

Scientific Reports, 2017, p. 46082, doi. 10.1038/srep46082

By:

Maitre, Léa;
Lau, Chung-Ho E.;
Vizcaino, Esther;
Robinson, Oliver;
Casas, Maribel;
Siskos, Alexandros P.;
Want, Elizabeth J.;
Athersuch, Toby;
Slama, Remy;
Vrijheid, Martine;
Keun, Hector C.;
Coen, Muireann

Publication type:

Article

Development of a rapid profiling method for the analysis of polar analytes in urine using HILIC-MS and ion mobility enabled HILIC-MS.

Published in:

Metabolomics, 2019, v. 15, n. 2, p. 1, doi. 10.1007/s11306-019-1474-9

By:

King, Adam M.;
Mullin, Lauren G.;
Wilson, Ian D.;
Coen, Muireann;
Rainville, Paul D.;
Plumb, Robert S.;
Gethings, Lee A.;
Maker, Garth;
Trengove, Robert

Publication type:

Article

Metabolomics in Toxicology and Preclinical Research.

Published in:

Altex, 2013, v. 30, n. 2, p. 209, doi. 10.14573/altex.2013.2.209

By:

Ramirez, Tzutzuy;
Daneshian, Mardas;
Kamp, Hennicke;
Bois, Frederic Y.;
Clench, Malcolm R.;
Coen, Muireann;
Donley, Beth;
Fischer, Steven M.;
Ekman, Drew R.;
Fabian, Eric;
Guillou, Claude;
Heuer, Joachim;
Hogberg, Helena T.;
Jungnickel, Harald;
Keun, Hector C.;
Krennrich, Gerhard;
Krupp, Eckart;
Luch, Andreas;
Noor, Fozia;
Peter, Erik

Publication type:

Article

Systems Level Metabolic Phenotype of Methotrexate Administration in the Context of Non-alcoholic Steatohepatitis in the Rat.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 105, doi. 10.1093/toxsci/kfu160

By:

Kyriakides, Michael;
Hardwick, Rhiannon N.;
Zhaosheng Jin;
Goedken, Michael J.;
Holmes, Elaine;
Cherrington, Nathan J.;
Coen, Muireann

Publication type:

Article

Metabolic Phenotyping for Enhanced Mechanistic Stratification of Chronic Hepatitis C-Induced Liver Fibrosis.

Published in:

American Journal of Gastroenterology (Springer Nature), 2015, v. 110, n. 1, p. 159, doi. 10.1038/ajg.2014.370

By:

Sands, Caroline J;
Guha, Indra N;
Kyriakides, Michael;
Wright, Mark;
Beckonert, Olaf;
Holmes, Elaine;
Rosenberg, William M;
Coen, Muireann

Publication type:

Article

In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children.

Published in:

2020

By:

Vives-Usano, Marta;
Hernandez-Ferrer, Carles;
Maitre, Léa;
Ruiz-Arenas, Carlos;
Andrusaityte, Sandra;
Borràs, Eva;
Carracedo, Ángel;
Casas, Maribel;
Chatzi, Leda;
Coen, Muireann;
Estivill, Xavier;
González, Juan R.;
Grazuleviciene, Regina;
Gutzkow, Kristine B.;
Keun, Hector C.;
Lau, Chung-Ho E.;
Cadiou, Solène;
Lepeule, Johanna;
Mason, Dan;
Quintela, Inés

Publication type:

journal article

Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure.

Published in:

Toxicological Sciences, 2020, v. 175, n. 1, p. 87, doi. 10.1093/toxsci/kfaa023

By:

Dargue, Rebecca;
Zia, Rabiya;
Lau, Chungho;
Nicholls, Andrew W;
Dare, Theo O;
Lee, Karla;
Jalan, Rajiv;
Coen, Muireann;
Wilson, Ian D

Publication type:

Article

Metabolic phenotyping applied to pre-clinical and clinical studies of acetaminophen metabolism and hepatotoxicity.

Published in:

Drug Metabolism Reviews, 2015, v. 47, n. 1, p. 29, doi. 10.3109/03602532.2014.982865

By:

Coen, Muireann

Publication type:

Article

Urinary metabolites of 2-bromoethanamine identified by stable isotope labelling: evidence for carbamoylation and glutathione conjugation.

Published in:

Xenobiotica, 2011, v. 41, n. 2, p. 144, doi. 10.3109/00498254.2010.529179

By:

Shipkova, Petia;
Vassallo, Jeffrey D.;
Aranibar, Nelly;
Hnatyshyn, Serhiy;
Zhang, Haiying;
Clayton, T. Andrew;
Cantor, Glenn H.;
Sanders, Mark;
Coen, Muireann;
Lindon, John C.;
Holmes, Elaine;
Nicholson, Jeremy K.;
Lehman-McKeeman, Lois

Publication type:

Article

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother–child cohort study.

Published in:

BMC Medicine, 2014, v. 12, n. 1, p. 110, doi. 10.1186/1741-7015-12-110

By:

Maitre, Léa;
Fthenou, Eleni;
Athersuch, Toby;
Coen, Muireann;
Toledano, Mireille B.;
Holmes, Elaine;
Kogevinas, Manolis;
Chatzi, Leda;
Keun, Hector C.

Publication type:

Article

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother-child cohort study.

Published in:

2014

By:

Maitre, Léa;
Fthenou, Eleni;
Athersuch, Toby;
Coen, Muireann;
Toledano, Mireille B;
Holmes, Elaine;
Kogevinas, Manolis;
Chatzi, Leda;
Keun, Hector C

Publication type:

journal article