Works by Cloughesy, Timothy F

Results: 153

Change in volumetric tumor growth rate after cytotoxic therapy is predictive of overall survival in recurrent glioblastoma.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad084

By:

Oshima, Sonoko;
Hagiwara, Akifumi;
Raymond, Catalina;
Wang, Chencai;
Cho, Nicholas S;
Lu, Jianwen;
Eldred, Blaine S C;
Nghiemphu, Phioanh L;
Lai, Albert;
Telesca, Donatello;
Salamon, Noriko;
Cloughesy, Timothy F;
Ellingson, Benjamin M

Publication type:

Article

A single-institution retrospective analysis of pathologically determined malignant transformation in IDH mutant glioma patients.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad036

By:

Liu, Vicki;
Wetzel, Ethan A;
Eldred, Blaine S C;
Rinonos, Serendipity Zapanta;
Prins, Terry J;
Khanlou, Negar;
Liau, Linda M;
Chong, Robert;
Nghiemphu, Phioanh L;
Cloughesy, Timothy F;
Ellingson, Benjamin M;
Lai, Albert

Publication type:

Article

Early volumetric, perfusion, and diffusion MRI changes after mutant isocitrate dehydrogenase (IDH) inhibitor treatment in IDH1-mutant gliomas.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac124

By:

Cho, Nicholas S.;
Akifumi Hagiwara;
Eldred, Blaine S. C.;
Raymond, Catalina;
Chencai Wang;
Sanvito, Francesco;
Lai, Albert;
Nghiemphu, Phioanh;
Salamon, Noriko;
Steelman, Lori;
Hassan, Islam;
Cloughesy, Timothy F.;
Ellingson, Benjamin M.

Publication type:

Article

Prognostic value of O<sup>6</sup>-methylguanine-DNA methyltransferase methylation in isocitrate dehydrogenase mutant gliomas.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac030

By:

Keng Lam;
Eldred, Blaine S. C.;
Kevan, Bryan;
Pianka, Sean;
Eldred, Brittany A.;
Rinonos, Serendipity Zapanta;
Yong, William H.;
Liau, Linda M.;
Nghiemphu, Phioanh L.;
Cloughesy, Timothy F.;
Green, Richard M.;
Lai, Albert

Publication type:

Article

Nivolumab plus radiotherapy with or without temozolomide in newly diagnosed glioblastoma: Results from exploratory phase I cohorts of CheckMate 143.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac025

By:

Omuro, Antonio;
Reardon, David A.;
Sampson, John H.;
Baehring, Joachim;
Sahebjam, Solmaz;
Cloughesy, Timothy F.;
Chalamandaris, Alexandros-Georgios;
Potter, Von;
Butowski, Nicholas;
Lim, Michael

Publication type:

Article

Author Correction: TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial.

Published in:

2024

By:

Everson, Richard G.;
Hugo, Willy;
Sun, Lu;
Antonios, Joseph;
Lee, Alexander;
Ding, Lizhong;
Bu, Melissa;
Khattab, Sara;
Chavez, Carolina;
Billingslea-Yoon, Emma;
Salazar, Andres;
Ellingson, Benjamin M.;
Cloughesy, Timothy F.;
Liau, Linda M.;
Prins, Robert M.

Publication type:

Correction Notice

TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48073-y

By:

Everson, Richard G.;
Hugo, Willy;
Sun, Lu;
Antonios, Joseph;
Lee, Alexander;
Ding, Lizhong;
Bu, Melissa;
Khattab, Sara;
Chavez, Carolina;
Billingslea-Yoon, Emma;
Salazar, Andres;
Ellingson, Benjamin M.;
Cloughesy, Timothy F.;
Liau, Linda M.;
Prins, Robert M.

Publication type:

Article

Multi-Parametric Radiomic Model to Predict 1p/19q Co-Deletion in Patients with IDH-1 Mutant Glioma: Added Value to the T2-FLAIR Mismatch Sign.

Published in:

Cancers, 2023, v. 15, n. 4, p. 1037, doi. 10.3390/cancers15041037

By:

Kihira, Shingo;
Derakhshani, Ahrya;
Leung, Michael;
Mahmoudi, Keon;
Bauer, Adam;
Zhang, Haoyue;
Polson, Jennifer;
Arnold, Corey;
Tsankova, Nadejda M.;
Hormigo, Adilia;
Salehi, Banafsheh;
Pham, Nancy;
Ellingson, Benjamin M.;
Cloughesy, Timothy F.;
Nael, Kambiz

Publication type:

Article

Diagnostic and Prognostic Value of pH- and Oxygen-Sensitive Magnetic Resonance Imaging in Glioma: A Retrospective Study.

Published in:

Cancers, 2022, v. 14, n. 10, p. 2520, doi. 10.3390/cancers14102520

By:

Yao, Jingwen;
Hagiwara, Akifumi;
Oughourlian, Talia C.;
Wang, Chencai;
Raymond, Catalina;
Pope, Whitney B.;
Salamon, Noriko;
Lai, Albert;
Ji, Matthew;
Nghiemphu, Phioanh L.;
Liau, Linda M.;
Cloughesy, Timothy F.;
Ellingson, Benjamin M.

Publication type:

Article

Phase I study of sorafenib and tipifarnib for recurrent glioblastoma: NABTC 05-02.

Published in:

Journal of Neuro-Oncology, 2018, v. 136, n. 1, p. 79, doi. 10.1007/s11060-017-2624-4

By:

Nghiemphu, Phioanh Leia;
Ebiana, Victoria Asuquo;
Wen, Patrick;
Gilbert, Mark;
Abrey, Lauren E.;
Lieberman, F.;
DeAngelis, Lisa M.;
Robins, H. Ian;
Yung, W. K. Alfred;
Chang, Susan;
Drappatz, Jan;
Mehta, Minesh P.;
Levin, Victor A.;
Aldape, Kenneth;
Dancey, Janet E.;
Wright, J. J.;
Prados, Michael;
Kuhn, John;
Cloughesy, Timothy F.

Publication type:

Article

Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone.

Published in:

Journal of Neuro-Oncology, 2010, v. 96, n. 3, p. 359, doi. 10.1007/s11060-009-9983-4

By:

Kappadakunnel, Melanie;
Eskin, Ascia;
Dong, Jun;
Nelson, Stanley F.;
Mischel, Paul S.;
Liau, Linda M.;
Phioanh Ngheimphu;
Lai, Albert;
Cloughesy, Timothy F.;
Goldin, Jonathan;
Pope, Whitney B.

Publication type:

Article

Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71799-w

By:

Patel, Kunal S.;
Yao, Jingwen;
Raymond, Catalina;
Yong, William;
Everson, Richard;
Liau, Linda M.;
Nathanson, David;
Kornblum, Harley;
Wang, Chencai;
Oughourlian, Talia;
Lai, Albert;
Nghiemphu, Phioanh L.;
Pope, Whitney B.;
Cloughesy, Timothy F.;
Ellingson, Benjamin M.

Publication type:

Article

Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68733-5

By:

Yao, Jingwen;
Hagiwara, Akifumi;
Raymond, Catalina;
Shabani, Soroush;
Pope, Whitney B.;
Salamon, Noriko;
Lai, Albert;
Ji, Matthew;
Nghiemphu, Phioanh L.;
Liau, Linda M.;
Cloughesy, Timothy F.;
Ellingson, Benjamin M.

Publication type:

Article

Digital "flipbooks" for enhanced visual assessment of simple and complex brain tumors.

Published in:

Neuro-Oncology, 2024, v. 26, n. 10, p. 1823, doi. 10.1093/neuonc/noae097

By:

Cho, Nicholas S;
Le, Viên Lam;
Sanvito, Francesco;
Oshima, Sonoko;
Harper, Jayla;
Chun, Saewon;
Raymond, Catalina;
Lai, Albert;
Nghiemphu, Phioanh L;
Yao, Jingwen;
Everson, Richard;
Salamon, Noriko;
Cloughesy, Timothy F;
Ellingson, Benjamin M

Publication type:

Article

pH-Weighted amine chemical exchange saturation transfer echo planar imaging visualizes infiltrating glioblastoma cells.

Published in:

Neuro-Oncology, 2024, v. 26, n. 1, p. 115, doi. 10.1093/neuonc/noad150

By:

Patel, Kunal S;
Yao, Jingwen;
Cho, Nicholas S;
Sanvito, Francesco;
Tessema, Kaleab;
Alvarado, Alvaro;
Dudley, Lindsey;
Rodriguez, Fausto;
Everson, Richard;
Cloughesy, Timothy F;
Salamon, Noriko;
Liau, Linda M;
Kornblum, Harley I;
Ellingson, Benjamin M

Publication type:

Article

Reply to Di Nunno et al. concerning objective response rates targets for recurrent glioblastoma clinical trials: Toward surrogate endpoints for phase II trials in patients with recurrent glioblastoma.

Published in:

Neuro-Oncology, 2023, v. 25, n. 8, p. 1548, doi. 10.1093/neuonc/noad085

By:

Ellingson, Benjamin M;
Wen, Patrick Y;
Cloughesy, Timothy F

Publication type:

Article

Diagnosis and management of complications from the treatment of primary central nervous system tumors in adults.

Published in:

Neuro-Oncology, 2023, v. 25, n. 7, p. 1200, doi. 10.1093/neuonc/noad038

By:

Weller, Michael;
Rhun, Emilie Le;
Bent, Martin Van den;
Chang, Susan M;
Cloughesy, Timothy F;
Goldbrunner, Roland;
Hong, Yong-Kil;
Jalali, Rakesh;
Jenkinson, Michael D;
Minniti, Giuseppe;
Nagane, Motoo;
Razis, Evangelia;
Roth, Patrick;
Rudà, Roberta;
Tabatabai, Ghazaleh;
Wen, Patrick Y;
Short, Susan C;
Preusser, Matthias

Publication type:

Article

Objective response rate targets for recurrent glioblastoma clinical trials based on the historic association between objective response rate and median overall survival.

Published in:

Neuro-Oncology, 2023, v. 25, n. 6, p. 1017, doi. 10.1093/neuonc/noad002

By:

Ellingson, Benjamin M;
Wen, Patrick Y;
Chang, Susan M;
van den Bent, Martin;
Vogelbaum, Michael A;
Li, Gang;
Li, Shanpeng;
Kim, Jiyoon;
Youssef, Gilbert;
Wick, Wolfgang;
Lassman, Andrew B;
Gilbert, Mark R;
Groot, John F de;
Weller, Michael;
Galanis, Evanthia;
Cloughesy, Timothy F

Publication type:

Article

17 Comparing Cognitive Patient-Reported Outcomes with Neuropsychological Impairment in Patients with Diffuse Glioma.

Published in:

2023

By:

Wall, Lucy;
Van Dyk, Kathleen;
Choi, Justin;
Raymond, Catalina;
Wang, Chencai;
Lai, Albert;
Cloughesy, Timothy F;
Ellingson, Benjamin M;
Nghiemphu, Phioanh

Publication type:

Abstract

Patient-specific characterization of the invasiveness and proliferation of low-grade gliomas using serial MR imaging and a mathematical model of tumor growth.

Published in:

Oncology Reports, 2015, v. 33, n. 6, p. 2883, doi. 10.3892/or.2015.3926

By:

HATHOUT, LEITH;
ELLINGSON, BENJAMIN M.;
CLOUGHESY, TIMOTHY F.;
POPE, WHITNEY B.

Publication type:

Article

Bone morphogenetic protein 7 sensitizes O6-methylguanine methyltransferase expressing-glioblastoma stem cells to clinically relevant dose of temozolomide.

Published in:

Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0459-1

By:

Tso, Jonathan L.;
Shuai Yang;
Menjivar, Jimmy C.;
Yamada, Kazunari;
Yibei Zhang;
Hong, Irene;
Bui, Yvonne;
Stream, Alexandra;
McBride, William H.;
Liau, Linda M.;
Nelson, Stanley F.;
Cloughesy, Timothy F.;
Yong, William H.;
Lai, Albert;
Cho-Lea Tso

Publication type:

Article

Novel methodology for the archiving and interactive reading of clinical magnetic resonance spectroscopic imaging.

Published in:

Magnetic Resonance in Medicine, 2002, v. 48, n. 3, p. 411, doi. 10.1002/mrm.10239

By:

Alger, Jeffry R.;
Frew, Andrew J.;
Cloughesy, Timothy F.;
del Vecchio, Walter;
Villablanca, J. Pablo;
Curran, John G.

Publication type:

Article

Inverse correlation between choline magnetic resonance spectroscopy signal intensity and the apparent diffusion coefficient in human glioma.

Published in:

Magnetic Resonance in Medicine, 1999, v. 41, n. 1, p. 2, doi. 10.1002/(SICI)1522-2594(199901)41:1<2::AID-MRM2>3.0.CO;2-Y

By:

Gupta, Rakesh K.;
Sinha, Usha;
Cloughesy, Timothy F.;
Alger, Jeffry R.

Publication type:

Article

Gene expression profiling identifies molecular subtypes of gliomas.

Published in:

Oncogene, 2003, v. 22, n. 31, p. 4918, doi. 10.1038/sj.onc.1206753

By:

Shai, Ruty;
Shi, Tao;
Kremen, Thomas J;
Horvath, Steve;
Liau, Linda M;
Cloughesy, Timothy F;
Mischel, Paul S;
Nelson, Stanley F

Publication type:

Article

Identification of molecular subtypes of glioblastoma by gene expression profiling.

Published in:

Oncogene, 2003, v. 22, n. 15, p. 2361, doi. 10.1038/sj.onc.1206344

By:

Mischel, Paul S;
Shai, Ruty;
Shi, Tao;
Horvath, Steve;
Lu, Kan V;
Choe, Gheeyoung;
Seligson, David;
Kremen, Thomas J;
Palotie, Aarno;
Liau, Linda M;
Cloughesy, Timothy F;
Nelson, Stanley F

Publication type:

Article

Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma.

Published in:

Nature Communications, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41467-024-54138-9

By:

Fernandez, Elizabeth G.;
Mai, Wilson X.;
Song, Kai;
Bayley, Nicholas A.;
Kim, Jiyoon;
Zhu, Henan;
Pioso, Marissa;
Young, Pauline;
Andrasz, Cassidy L.;
Cadet, Dimitri;
Liau, Linda M.;
Li, Gang;
Yong, William H.;
Rodriguez, Fausto J.;
Dixon, Scott J.;
Souers, Andrew J.;
Li, Jingyi Jessica;
Graeber, Thomas G.;
Cloughesy, Timothy F.;
Nathanson, David A.

Publication type:

Article

Author Correction: TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial.

Published in:

2024

By:

Everson, Richard G.;
Hugo, Willy;
Sun, Lu;
Antonios, Joseph;
Lee, Alexander;
Ding, Lizhong;
Bu, Melissa;
Khattab, Sara;
Chavez, Carolina;
Billingslea-Yoon, Emma;
Salazar, Andres;
Ellingson, Benjamin M.;
Cloughesy, Timothy F.;
Liau, Linda M.;
Prins, Robert M.

Publication type:

Correction Notice

Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma.

Published in:

Stem Cells, 2009, v. 27, n. 4, p. 980, doi. 10.1002/stem.15

By:

Laks, Dan R.;
Masterman-Smith, Michael;
Visnyei, Koppany;
Angenieux, Brigitte;
Orozco, Nicholas M.;
Foran, Ian;
Yong, William H.;
Vinters, Harry V.;
Liau, Linda M.;
Lazareff, Jorge A.;
Cloughesy, Timothy F.;
Horvath, Steve;
Kornblum, Harley I.

Publication type:

Article

Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma.

Published in:

Nature Reviews Cancer, 2015, v. 15, n. 5, p. 302, doi. 10.1038/nrc3918

By:

Furnari, Frank B.;
Cloughesy, Timothy F.;
Cavenee, Webster K.;
Mischel, Paul S.

Publication type:

Article

Regional and Voxel-Wise Comparisons of Blood Flow Measurements Between Dynamic Susceptibility Contrast Magnetic Resonance Imaging (DSC-MRI) and Arterial Spin Labeling (ASL) in Brain Tumors.

Published in:

Journal of Neuroimaging, 2014, v. 24, n. 1, p. 23, doi. 10.1111/j.1552-6569.2012.00703.x

By:

White, Carissa M.;
Pope, Whitney B.;
Zaw, Taryar;
Qiao, Joe;
Naeini, Kourosh M.;
Lai, Albert;
Nghiemphu, Phioanh L.;
Wang, J.J.;
Cloughesy, Timothy F.;
Ellingson, Benjamin M.

Publication type:

Article

Corrigendum to: EGFR, the Lazarus target for precision oncology in glioblastoma.

Published in:

2023

By:

Lin, Benjamin;
Ziebro, Julia;
Smithberger, Erin;
Skinner, Kasey R;
Zhao, Eva;
Cloughesy, Timothy F;
Binder, Zev A;
O'Rourke, Donald M;
Nathanson, David A;
Furnari, Frank B;
Miller, C Ryan

Publication type:

Correction Notice

EGFR, the Lazarus target for precision oncology in glioblastoma.

Published in:

Neuro-Oncology, 2022, v. 24, n. 12, p. 2035, doi. 10.1093/neuonc/noac204

By:

Lin, Benjamin;
Ziebro, Julia;
Smithberger, Erin;
Skinner, Kasey R;
Zhao, Eva;
Cloughesy, Timothy F;
Binder, Zev A;
O'Rourke, Donald M;
Nathanson, David A;
Furnari, Frank B;
Miller, C Ryan

Publication type:

Article

Diffusion MRI is an early biomarker of overall survival benefit in IDH wild-type recurrent glioblastoma treated with immune checkpoint inhibitors.

Published in:

Neuro-Oncology, 2022, v. 24, n. 6, p. 1020, doi. 10.1093/neuonc/noab276

By:

Hagiwara, Akifumi;
Oughourlian, Talia C;
Cho, Nicholas S;
Schlossman, Jacob;
Wang, Chencai;
Yao, Jingwen;
Raymond, Catalina;
Everson, Richard;
Patel, Kunal;
Mareninov, Sergey;
Rodriguez, Fausto J;
Salamon, Noriko;
Pope, Whitney B;
Nghiemphu, Phioanh L;
Liau, Linda M;
Prins, Robert M;
Cloughesy, Timothy F;
Ellingson, Benjamin M

Publication type:

Article

Volumetric measurements are preferred in the evaluation of mutant IDH inhibition in non-enhancing diffuse gliomas: Evidence from a phase I trial of ivosidenib.

Published in:

Neuro-Oncology, 2022, v. 24, n. 5, p. 770, doi. 10.1093/neuonc/noab256

By:

Ellingson, Benjamin M;
Kim, Grace Hyun J;
Brown, Matt;
Lee, Jihey;
Salamon, Noriko;
Steelman, Lori;
Hassan, Islam;
Pandya, Shuchi S;
Chun, Saewon;
Linetsky, Michael;
Yoo, Bryan;
Wen, Patrick Y;
Mellinghoff, Ingo K;
Goldin, Jonathan;
Cloughesy, Timothy F

Publication type:

Article

Early results from the CODEL trial for anaplastic oligodendrogliomas: is temozolomide futile?

Published in:

Neuro-Oncology, 2021, v. 23, n. 3, p. 347, doi. 10.1093/neuonc/noab006

By:

Lassman, Andrew B;
Cloughesy, Timothy F

Publication type:

Article

Radiographic read paradigms and the roles of the central imaging laboratory in neuro-oncology clinical trials.

Published in:

Neuro-Oncology, 2021, v. 23, n. 2, p. 189, doi. 10.1093/neuonc/noaa253

By:

Ellingson, Benjamin M;
Brown, Matthew S;
Boxerman, Jerrold L;
Gerstner, Elizabeth R;
Kaufmann, Timothy J;
Cole, Patricia E;
Bacha, Jeffrey A;
Leung, David;
Barone, Amy;
Colman, Howard;
Bent, Martin J van den;
Wen, Patrick Y;
Yung, W K Alfred;
Cloughesy, Timothy F;
Goldin, Jonathan G

Publication type:

Article

Development of a gene expression–based prognostic signature for IDH wild-type glioblastoma.

Published in:

Neuro-Oncology, 2020, v. 22, n. 12, p. 1742, doi. 10.1093/neuonc/noaa157

By:

Johnson, Radia M;
Phillips, Heidi S;
Bais, Carlos;
Brennan, Cameron W;
Cloughesy, Timothy F;
Daemen, Anneleen;
Herrlinger, Ulrich;
Jenkins, Robert B;
Lai, Albert;
Mancao, Christoph;
Weller, Michael;
Wick, Wolfgang;
Bourgon, Richard;
Garcia, Josep

Publication type:

Article

Volumetric analysis of IDH-mutant lower-grade glioma: a natural history study of tumor growth rates before and after treatment.

Published in:

Neuro-Oncology, 2020, v. 22, n. 12, p. 1822, doi. 10.1093/neuonc/noaa105

By:

Huang, Raymond Y;
Young, Robert J;
Ellingson, Benjamin M;
Veeraraghavan, Harini;
Wang, Wei;
Tixier, Florent;
Um, Hyemin;
Nawaz, Rasheed;
Luks, Tracy;
Kim, John;
Gerstner, Elizabeth R;
Schiff, David;
Peters, Katherine B;
Mellinghoff, Ingo K;
Chang, Susan M;
Cloughesy, Timothy F;
Wen, Patrick Y

Publication type:

Article

Emerging immunotherapies for malignant glioma: from immunogenomics to cell therapy.

Published in:

Neuro-Oncology, 2020, v. 22, n. 10, p. 1425, doi. 10.1093/neuonc/noaa154

By:

Dunn, Gavin P;
Cloughesy, Timothy F;
Maus, Marcela V;
Prins, Robert M;
Reardon, David A;
Sonabend, Adam M

Publication type:

Article

Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas.

Published in:

Neuro-Oncology, 2020, v. 22, n. 9, p. 1262, doi. 10.1093/neuonc/noaa141

By:

Boxerman, Jerrold L;
Quarles, Chad C;
Hu, Leland S;
Erickson, Bradley J;
Gerstner, Elizabeth R;
Smits, Marion;
Kaufmann, Timothy J;
Barboriak, Daniel P;
Huang, Raymond H;
Wick, Wolfgang;
Weller, Michael;
Galanis, Evanthia;
Kalpathy-Cramer, Jayashree;
Shankar, Lalitha;
Jacobs, Paula;
Chung, Caroline;
Bent, Martin J van den;
Chang, Susan;
Yung, W K Al;
Cloughesy, Timothy F

Publication type:

Article

Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.

Published in:

Neuro-Oncology, 2020, v. 22, n. 8, p. 1073, doi. 10.1093/neuonc/noaa106

By:

Wen, Patrick Y;
Weller, Michael;
Lee, Eudocia Quant;
Alexander, Brian M;
Barnholtz-Sloan, Jill S;
Barthel, Floris P;
Batchelor, Tracy T;
Bindra, Ranjit S;
Chang, Susan M;
Chiocca, E Antonio;
Cloughesy, Timothy F;
DeGroot, John F;
Galanis, Evanthia;
Gilbert, Mark R;
Hegi, Monika E;
Horbinski, Craig;
Huang, Raymond Y;
Lassman, Andrew B;
Rhun, Emilie Le;
Lim, Michael

Publication type:

Article

A randomized controlled phase III study of VB-111 combined with bevacizumab vs bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE).

Published in:

Neuro-Oncology, 2020, v. 22, n. 5, p. 705, doi. 10.1093/neuonc/noz232

By:

Cloughesy, Timothy F;
Brenner, Andrew;
Groot, John F de;
Butowski, Nicholas A;
Zach, Leor;
Campian, Jian L;
Ellingson, Benjamin M;
Freedman, Laurence S;
Cohen, Yael C;
Lowenton-Spier, Noa;
Minei, Tamar Rachmilewitz;
Shmueli, Shifra Fain;
Investigators, GLOBE Study;
Y, Wen Patrick

Publication type:

Article

Safety and efficacy of VB-111, an anticancer gene therapy, in patients with recurrent glioblastoma: results of a phase I/II study.

Published in:

Neuro-Oncology, 2020, v. 22, n. 5, p. 694, doi. 10.1093/neuonc/noz231

By:

Brenner, Andrew J;
Peters, Katherine B;
Vredenburgh, James;
Bokstein, Felix;
Blumenthal, Deborah T;
Yust-Katz, Shlomit;
Peretz, Idit;
Oberman, Bernice;
Freedman, Laurence S;
Ellingson, Benjamin M;
Cloughesy, Timothy F;
Sher, Naamit;
Cohen, Yael C;
Lowenton-Spier, Noa;
Minei, Tamar Rachmilewitz;
Yakov, Niva;
Mendel, Itzhak;
Breitbart, Eyal;
Wen, Patrick Y

Publication type:

Article

To randomize, or not to randomize, that is the question: using data from prior clinical trials to guide future designs.

Published in:

Neuro-Oncology, 2019, v. 21, n. 10, p. 1239, doi. 10.1093/neuonc/noz097

By:

Vanderbeek, Alyssa M;
Ventz, Steffen;
Rahman, Rifaquat;
Fell, Geoffrey;
Cloughesy, Timothy F;
Wen, Patrick Y;
Trippa, Lorenzo;
Alexander, Brian M

Publication type:

Article

Metabolic characterization of human IDH mutant and wild type gliomas using simultaneous pH- and oxygen-sensitive molecular MRI.

Published in:

Neuro-Oncology, 2019, v. 21, n. 9, p. 1184, doi. 10.1093/neuonc/noz078

By:

Yao, Jingwen;
Chakhoyan, Ararat;
Nathanson, David A;
Yong, William H;
Salamon, Noriko;
Raymond, Catalina;
Mareninov, Sergey;
Lai, Albert;
Nghiemphu, Phioanh L;
Prins, Robert M;
Pope, Whitney B;
Everson, Richard G;
Liau, Linda M;
Cloughesy, Timothy F;
Ellingson, Benjamin M

Publication type:

Article

Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC.

Published in:

Neuro-Oncology, 2018, v. 20, n. 10, p. 1383, doi. 10.1093/neuonc/noy075

By:

Cloughesy, Timothy F;
Landolfi, Joseph;
Vogelbaum, Michael A;
Ostertag, Derek;
Elder, James B;
Bloomfield, Stephen;
Carter, Bob;
Chen, Clark C;
Kalkanis, Steven N;
Kesari, Santosh

Publication type:

Article

Is it time to reconsider the role of irinotecan for the treatment of high-grade gliomas?

Published in:

Neuro-Oncology, 2018, v. 20, n. 8, p. 1144, doi. 10.1093/neuonc/noy092

By:

Lee, Eudocia Quant;
McFaline-Figueroa, J Ricardo;
Cloughesy, Timothy F;
Wen, Patrick Y

Publication type:

Article

The clinical trials landscape for glioblastoma: is it adequate to develop new treatments?

Published in:

Neuro-Oncology, 2018, v. 20, n. 8, p. 1034, doi. 10.1093/neuonc/noy027

By:

Vanderbeek, Alyssa M;
Rahman, Rifaquat;
Fell, Geoffrey;
Ventz, Steffen;
Chen, Tianqi;
Redd, Robert;
Parmigiani, Giovanni;
Cloughesy, Timothy F;
Wen, Patrick Y;
Trippa, Lorenzo

Publication type:

Article

Platform trials arrive on time for glioblastoma.

Published in:

Neuro-Oncology, 2018, v. 20, n. 6, p. 723, doi. 10.1093/neuonc/noy040

By:

Alexander, Brian M.;
Cloughesy, Timothy F.

Publication type:

Article

Evidence and context of use for contrast enhancement as a surrogate of disease burden and treatment response in malignant glioma.

Published in:

Neuro-Oncology, 2018, v. 20, n. 4, p. 457, doi. 10.1093/neuonc/nox193

By:

Ellingson, Benjamin M.;
Wen, Patrick Y.;
Cloughesy, Timothy F.

Publication type:

Article