Works by Clohessy, John G

Results: 16

Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs.

Published in:

Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02263-9

By:

Zhang, Yang;
Nguyen, Tuan M.;
Zhang, Xiao-Ou;
Wang, Limei;
Phan, Tin;
Clohessy, John G.;
Pandolfi, Pier Paolo

Publication type:

Article

The Tug1 lncRNA locus is essential for male fertility.

Published in:

Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-020-02081-5

By:

Lewandowski, Jordan P.;
Dumbović, Gabrijela;
Watson, Audrey R.;
Hwang, Taeyoung;
Jacobs-Palmer, Emily;
Chang, Nydia;
Much, Christian;
Turner, Kyle M.;
Kirby, Christopher;
Rubinstein, Nimrod D.;
Groff, Abigail F.;
Liapis, Steve C.;
Gerhardinger, Chiara;
Bester, Assaf;
Pandolfi, Pier Paolo;
Clohessy, John G.;
Hoekstra, Hopi E.;
Sauvageau, Martin;
Rinn, John L.

Publication type:

Article

A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.

Published in:

Nature Genetics, 2013, v. 45, n. 7, p. 747, doi. 10.1038/ng.2650

By:

Lunardi, Andrea;
Ala, Ugo;
Epping, Mirjam T;
Salmena, Leonardo;
Clohessy, John G;
Webster, Kaitlyn A;
Wang, Guocan;
Mazzucchelli, Roberta;
Bianconi, Maristella;
Stack, Edward C;
Lis, Rosina;
Patnaik, Akash;
Cantley, Lewis C;
Bubley, Glenn;
Cordon-Cardo, Carlos;
Gerald, William L;
Montironi, Rodolfo;
Signoretti, Sabina;
Loda, Massimo;
Nardella, Caterina

Publication type:

Article

Subtle variations in Pten dose determine cancer susceptibility.

Published in:

Nature Genetics, 2010, v. 42, n. 5, p. 454, doi. 10.1038/ng.556

By:

Alimonti, Andrea;
Carracedo, Arkaitz;
Clohessy, John G.;
Trotman, Lloyd C.;
Nardella, Caterina;
Egia, Ainara;
Salmena, Leonardo;
Sampieri, Katia;
Haveman, William J.;
Brogi, Edi;
Richardson, Andrea L.;
Jiangwen Zhang;
Pandolfi, Pier Paolo

Publication type:

Article

The Mouse Hospital and Its Integration in Ultra-Precision Approaches to Cancer Care.

Published in:

Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00340

By:

Clohessy, John G.;
Pandolfi, Pier Paolo

Publication type:

Article

The RNA Binding Protein ESRP1 Fine-Tunes the Expression of Pluripotency-Related Factors in Mouse Embryonic Stem Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072300

By:

Fagoonee, Sharmila;
Bearzi, Claudia;
Di Cunto, Ferdinando;
Clohessy, John G.;
Rizzi, Roberto;
Reschke, Markus;
Tolosano, Emanuela;
Provero, Paolo;
Pandolfi, Pier Paolo;
Silengo, Lorenzo;
Altruda, Fiorella

Publication type:

Article

Differential Requirement of mTOR in Postmitotic Tissues and Tumorigenesis.

Published in:

Science Signaling, 2009, v. 2, n. 55, p. 1, doi. 10.1126/scisignal.2000189

By:

Nardella, Caterina;
Carracedo, Arkaitz;
Alimonti, Andrea;
Hobbs, Robin M.;
Clohessy, John G.;
Chen, Zhenbang;
Egia, Ainara;
Fornari, Alessandro;
Fiorentino, Michelangelo;
Loda, Massimo;
Kozma, Sara C.;
Thomas, George;
Cordon-Cardo, Carlos;
Pandolfi, Pier Paolo

Publication type:

Article

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.

Published in:

2010

By:

Alimonti, Andrea;
Nardella, Caterina;
Zhenbang Chen;
Clohessy, John G.;
Carracedo, Arkaitz;
Trotman, Lloyd C.;
Ke Cheng;
Varmeh, Shohreh;
Kozma, Sara C.;
Thomas, George;
Rosivatz, Erika;
Woscholski, Rudiger;
Cognetti, Francesco;
Scher, Howard I.;
Pandolfi, Pier Paolo;
Chen, Zhenbang;
Cheng, Ke

Publication type:

journal article

Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02272-y

By:

Ming Chen;
Lixin Wan;
Jiangwen Zhang;
Jinfang Zhang;
Mendez, Lourdes;
Clohessy, John G.;
Berry, Kelsey;
Victor, Joshua;
Qing Yin;
Yuan Zhu;
Wenyi Wei;
Pandolfi, Pier Paolo

Publication type:

Article

SPAR, a lncRNA encoded mTORC1 inhibitor.

Published in:

Cell Cycle, 2017, v. 16, n. 9, p. 815, doi. 10.1080/15384101.2017.1304735

By:

Matsumoto, Akinobu;
Clohessy, John G.;
Pandolfi, Pier Paolo

Publication type:

Article

Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 3, p. 1, doi. 10.15252/emmm.201708313

By:

Ali, Azhar;
Levantini, Elena;
Teo, Jun Ting;
Goggi, Julian;
Clohessy, John G;
Wu, Chan Shuo;
Chen, Leilei;
Yang, Henry;
Krishnan, Indira;
Kocher, Olivier;
Zhang, Junyan;
Soo, Ross A;
Bhakoo, Kishore;
Chin, Tan Min;
Tenen, Daniel G

Publication type:

Article

Pro-senescence therapy for cancer treatment.

Published in:

2011

By:

Nardella, Caterina;
Clohessy, John G.;
Alimonti, Andrea;
Pandolfi, Pier Paolo

Publication type:

journal article

Targeting of microRNA-22 Suppresses Tumor Spread in a Mouse Model of Triple-Negative Breast Cancer.

Published in:

Biomedicines, 2023, v. 11, n. 5, p. 1470, doi. 10.3390/biomedicines11051470

By:

Panella, Riccardo;
Cotton, Cody A.;
Maymi, Valerie A.;
Best, Sachem;
Berry, Kelsey E.;
Lee, Samuel;
Batalini, Felipe;
Vlachos, Ioannis S.;
Clohessy, John G.;
Kauppinen, Sakari;
Paolo Pandolfi, Pier

Publication type:

Article

Reciprocal antagonism of PIN1-APC/C<sup>CDH1</sup> governs mitotic protein stability and cell cycle entry.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47427-w

By:

Ke, Shizhong;
Dang, Fabin;
Wang, Lin;
Chen, Jia-Yun;
Naik, Mandar T.;
Li, Wenxue;
Thavamani, Abhishek;
Kim, Nami;
Naik, Nandita M.;
Sui, Huaxiu;
Tang, Wei;
Qiu, Chenxi;
Koikawa, Kazuhiro;
Batalini, Felipe;
Stern Gatof, Emily;
Isaza, Daniela Arango;
Patel, Jaymin M.;
Wang, Xiaodong;
Clohessy, John G.;
Heng, Yujing J.

Publication type:

Article

Characterisation of Mcl-1 cleavage during apoptosis of haematopoietic cells.

Published in:

British Journal of Haematology, 2004, v. 125, n. 5, p. 655, doi. 10.1111/j.1365-2141.2004.04949.x

By:

Clohessy, John G.;
Jianguo Zhuang;
Brady, Hugh J. M.

Publication type:

Article

Found in translation of mTOR signaling.

Published in:

Cell Research, 2012, v. 22, n. 9, p. 1315, doi. 10.1038/cr.2012.85

By:

Clohessy, John G;
Reschke, Markus;
Pandolfi, Pier Paolo

Publication type:

Article