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miR-375 is cold exposure sensitive and drives thermogenesis in visceral adipose tissue derived stem cells.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13610-6
By:
- Seeliger, Claudine;
- Krauss, Tanja;
- Honecker, Julius;
- Mengel, Laura Aline;
- Buekens, Lise;
- Mesas-Fernández, Alberto;
- Skurk, Thomas;
- Claussnitzer, Melina;
- Hauner, Hans
Publication type:
Article
BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35704-5
By:
- Agrawal, Saaket;
- Klarqvist, Marcus D. R.;
- Diamant, Nathaniel;
- Stanley, Takara L.;
- Ellinor, Patrick T.;
- Mehta, Nehal N.;
- Philippakis, Anthony;
- Ng, Kenney;
- Claussnitzer, Melina;
- Grinspoon, Steven K.;
- Batra, Puneet;
- Khera, Amit V.
Publication type:
Article
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30931-2
By:
- Agrawal, Saaket;
- Wang, Minxian;
- Klarqvist, Marcus D. R.;
- Smith, Kirk;
- Shin, Joseph;
- Dashti, Hesam;
- Diamant, Nathaniel;
- Choi, Seung Hoan;
- Jurgens, Sean J.;
- Ellinor, Patrick T.;
- Philippakis, Anthony;
- Claussnitzer, Melina;
- Ng, Kenney;
- Udler, Miriam S.;
- Batra, Puneet;
- Khera, Amit V.
Publication type:
Article
Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 9, p. 2217, doi. 10.1210/clinem/dgad148
By:
- Jersin, Regine Å.;
- Tallapragada, Divya Sri Priyanka;
- Skartveit, Linn;
- Bjune, Mona S.;
- Muniandy, Maheswary;
- Lee-Ødegård, Sindre;
- Heinonen, Sini;
- Alvarez, Marcus;
- Birkeland, Kåre Inge;
- Drevon, Christian André;
- Pajukanta, Päivi;
- McCann, Adrian;
- Pietiläinen, Kirsi H.;
- Claussnitzer, Melina;
- Mellgren, Gunnar;
- Dankel, Simon N.
Publication type:
Article
Gender Differences in the Response to Short-term Cold Exposure in Young Adults.
Published in:
2020
By:
- Mengel, Laura A;
- Seidl, Hatti;
- Brandl, Beate;
- Skurk, Thomas;
- Holzapfel, Christina;
- Stecher, Lynne;
- Claussnitzer, Melina;
- Hauner, Hans
Publication type:
journal article
Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.
Published in:
Nucleic Acids Research, 2017, v. 45, n. 6, p. 3266, doi. 10.1093/nar/gkx105
By:
- Heekyoung Lee;
- Kun Qian;
- von Toerne, Christine;
- Hoerburger, Lena;
- Claussnitzer, Melina;
- Hoffmann, Christoph;
- Glunk, Viktoria;
- Wahl, Simone;
- Breier, Michaela;
- Eck, Franziska;
- Jafari, Leili;
- Molnos, Sophie;
- Grallert, Harald;
- Dahlman, Ingrid;
- Arner, Peter;
- Brunner, Cornelia;
- Hauner, Hans;
- Hauck, Stefanie M.;
- Laumen, Helmut
Publication type:
Article
Octamer-dependent transcription in T cells is mediated by NFAT and NF-κB.
Published in:
Nucleic Acids Research, 2013, v. 41, n. 4, p. 2138, doi. 10.1093/nar/gks1349
By:
- Mueller, Kerstin;
- Quandt, Jasmin;
- Marienfeld, Ralf B.;
- Weihrich, Petra;
- Fiedler, Katja;
- Claussnitzer, Melina;
- Laumen, Helmut;
- Vaeth, Martin;
- Berberich-Siebelt, Friederike;
- Serfling, Edgar;
- Wirth, Thomas;
- Brunner, Cornelia
Publication type:
Article
Lipid droplet–size mapping in human adipose tissue using a clinical 3T system.
Published in:
Magnetic Resonance in Medicine, 2021, v. 86, n. 3, p. 1256, doi. 10.1002/mrm.28755
By:
- Weidlich, Dominik;
- Honecker, Julius;
- Boehm, Christof;
- Ruschke, Stefan;
- Junker, Daniela;
- Van, Anh T.;
- Makowski, Marcus R.;
- Holzapfel, Christina;
- Claussnitzer, Melina;
- Hauner, Hans;
- Karampinos, Dimitrios C.
Publication type:
Article
Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover.
Published in:
Diabetologia, 2023, v. 66, n. 7, p. 1289, doi. 10.1007/s00125-023-05915-6
By:
- Huang, Mi;
- Claussnitzer, Melina;
- Saadat, Alham;
- Coral, Daniel E.;
- Kalamajski, Sebastian;
- Franks, Paul W.
Publication type:
Article
Plasma Metabolomics Reveal Alterations of Sphingo- and Glycerophospholipid Levels in Non-Diabetic Carriers of the Transcription Factor 7-Like 2 Polymorphism rs7903146.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078430
By:
- Then, Cornelia;
- Wahl, Simone;
- Kirchhofer, Anna;
- Grallert, Harald;
- Krug, Susanne;
- Kastenmüller, Gabi;
- Römisch-Margl, Werner;
- Claussnitzer, Melina;
- Illig, Thomas;
- Heier, Margit;
- Meisinger, Christa;
- Adamski, Jerzy;
- Thorand, Barbara;
- Huth, Cornelia;
- Peters, Annette;
- Prehn, Cornelia;
- Heukamp, Ina;
- Laumen, Helmut;
- Lechner, Andreas;
- Hauner, Hans
Publication type:
Article
High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07746-1
By:
- Wang, Xinchen;
- He, Liang;
- Goggin, Sarah M.;
- Saadat, Alham;
- Wang, Li;
- Sinnott-Armstrong, Nasa;
- Claussnitzer, Melina;
- Kellis, Manolis
Publication type:
Article
Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele.
Published in:
Metabolomics, 2014, v. 10, n. 3, p. 386, doi. 10.1007/s11306-013-0586-x
By:
- Wahl, Simone;
- Krug, Susanne;
- Then, Cornelia;
- Kirchhofer, Anna;
- Kastenmüller, Gabi;
- Brand, Tina;
- Skurk, Thomas;
- Claussnitzer, Melina;
- Huth, Cornelia;
- Heier, Margit;
- Meisinger, Christa;
- Peters, Annette;
- Thorand, Barbara;
- Gieger, Christian;
- Prehn, Cornelia;
- Römisch-Margl, Werner;
- Adamski, Jerzy;
- Suhre, Karsten;
- Illig, Thomas;
- Grallert, Harald
Publication type:
Article
Minimum information and guidelines for reporting a multiplexed assay of variant effect.
Published in:
Genome Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13059-024-03223-9
By:
- Claussnitzer, Melina;
- Parikh, Victoria N.;
- Wagner, Alex H.;
- Arbesfeld, Jeremy A.;
- Bult, Carol J.;
- Firth, Helen V.;
- Muffley, Lara A.;
- Nguyen Ba, Alex N.;
- Riehle, Kevin;
- Roth, Frederick P.;
- Tabet, Daniel;
- Bolognesi, Benedetta;
- Glazer, Andrew M.;
- Rubin, Alan F.
Publication type:
Article
Effect of flavonoids on basal and insulin-stimulated 2-deoxyglucose uptake in adipocytes.
Published in:
Molecular Nutrition & Food Research, 2011, v. 55, p. S26, doi. 10.1002/mnfr.201000372
By:
- Claussnitzer, Melina;
- Skurk, Thomas;
- Hauner, Hans;
- Daniel, Hannelore;
- Rist, Manuela J.
Publication type:
Article
Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits.
Published in:
PLoS Computational Biology, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.pcbi.1008044
By:
- Glastonbury, Craig A.;
- Pulit, Sara L.;
- Honecker, Julius;
- Censin, Jenny C.;
- Laber, Samantha;
- Yaghootkar, Hanieh;
- Rahmioglu, Nilufer;
- Pastel, Emilie;
- Kos, Katerina;
- Pitt, Andrew;
- Hudson, Michelle;
- Nellåker, Christopher;
- Beer, Nicola L.;
- Hauner, Hans;
- Becker, Christian M.;
- Zondervan, Krina T.;
- Frayling, Timothy M.;
- Claussnitzer, Melina;
- Lindgren, Cecilia M.
Publication type:
Article
Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.84168
By:
- Mi Huang;
- Coral, Daniel;
- Ardalani, Hamidreza;
- Spegel, Peter;
- Saadat, Alham;
- Claussnitzer, Melina;
- Mulder, Hindrik;
- Franks, Paul W.;
- Kalamajski, Sebastian
Publication type:
Article
Specific miRNAs are associated with human cancer cachexia in an organ‐specific manner.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2023, v. 14, n. 3, p. 1381, doi. 10.1002/jcsm.13224
By:
- Krauss, Tanja;
- Heisz, Simone;
- Honecker, Julius;
- Prokopchuk, Olga;
- Martignoni, Marc;
- Janssen, Klaus‐Peter;
- Claussnitzer, Melina;
- Hauner, Hans;
- Seeliger, Claudine
Publication type:
Article
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.
Published in:
2016
By:
- Nielson, Carrie M;
- Liu, Ching-Ti;
- Smith, Albert V;
- Ackert-Bicknell, Cheryl L;
- Reppe, Sjur;
- Jakobsdottir, Johanna;
- Wassel, Christina;
- Register, Thomas C;
- Oei, Ling;
- Alonso, Nerea;
- Oei, Edwin H;
- Parimi, Neeta;
- Samelson, Elizabeth J;
- Nalls, Mike A;
- Zmuda, Joseph;
- Lang, Thomas;
- Bouxsein, Mary;
- Latourelle, Jeanne;
- Claussnitzer, Melina;
- Siggeirsdottir, Kristin
Publication type:
Other
COL6A3 expression in adipocytes associates with insulin resistance and depends on PPAR[gamma] and adipocyte size.
Published in:
2014
By:
- Dankel, Simon N;
- Svärd, Jessica;
- Matthä, Simone;
- Claussnitzer, Melina;
- Klöting, Nora;
- Glunk, Viktoria;
- Fandalyuk, Zinayida;
- Grytten, Elise;
- Solsvik, Margit H;
- Nielsen, Hans-Jørgen;
- Busch, Christian;
- Hauner, Hans;
- Blüher, Matthias;
- Skurk, Thomas;
- Sagen, Jørn V;
- Mellgren, Gunnar
Publication type:
Journal Article
COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size.
Published in:
Obesity (19307381), 2014, v. 22, n. 8, p. 1807, doi. 10.1002/oby.20758
By:
- Dankel, Simon N.;
- Svärd, Jessica;
- Matthä, Simone;
- Claussnitzer, Melina;
- Klöting, Nora;
- Glunk, Viktoria;
- Fandalyuk, Zinayida;
- Grytten, Elise;
- Solsvik, Margit H.;
- Nielsen, Hans‐Jørgen;
- Busch, Christian;
- Hauner, Hans;
- Blüher, Matthias;
- Skurk, Thomas;
- Sagen, Jørn V.;
- Mellgren, Gunnar
Publication type:
Article
Effect of BMI on the Thermogenic Response to Cold Exposure and Associated Changes in Metabolism and Browning Markers in Adult Humans.
Published in:
Obesity Facts: The European Journal of Obesity, 2022, v. 15, n. 3, p. 405, doi. 10.1159/000522218
By:
- Mengel, Laura Aline;
- Nemati Moud, Bahareh;
- Seidl, Hatti;
- Mesas-Fernández, Alberto;
- Seeliger, Claudine;
- Brandl, Beate;
- Skurk, Thomas;
- Holzapfel, Christina;
- Claussnitzer, Melina;
- Hauner, Hans
Publication type:
Article
Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data.
Published in:
Diabetes, 2009, v. 58, n. 4, p. 984, doi. 10.2337/db07-1646
By:
- Laumen, Helmut;
- Saningong, Akuma D.;
- Heid, Iris M.;
- Hess, Jochen;
- Herder, Christian;
- Claussnitzer, Melina;
- Baumert, Jens;
- Lamina, Claudia;
- Rathmann, Wolfgang;
- Sedlmeier, Eva-Maria;
- Klopp, Norman;
- Thorand, Barbara;
- Wichmann, H.-Erich;
- Illig, Thomas;
- Hauner, Hans
Publication type:
Article

Found: 22