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Cre‐loxP mediated control of PrP to study transmissible spongiform encephalopathy diseases.
- Published in:
- Genesis: The Journal of Genetics & Development, 2004, v. 40, n. 1, p. 1, doi. 10.1002/gene.20046
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- Publication type:
- Article
Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency.
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- Oncogene, 2002, v. 21, n. 42, p. 6446, doi. 10.1038/sj.onc.1205892
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- Publication type:
- Article
Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient background.
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- Oncogene, 2002, v. 21, n. 41, p. 6299, doi. 10.1038/sj.onc.1205727
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- Publication type:
- Article
The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient mice.
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- Oncogene, 2002, v. 21, n. 38, p. 5934, doi. 10.1038/sj.onc.1205760
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- Publication type:
- Article
Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes.
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- Oncogene, 2002, v. 21, n. 30, p. 4696, doi. 10.1038/sj.onc.1205673
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- Publication type:
- Article
Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent manner.
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- Oncogene, 2001, v. 20, n. 27, p. 3580, doi. 10.1038/sj.onc.1204449
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- Publication type:
- Article
A role for mismatch repair in control of DNA ploidy following DNA damage.
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- Oncogene, 2001, v. 20, n. 15, p. 1923, doi. 10.1038/sj.onc.1204276
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- Publication type:
- Article
A novel role for IRF-1 as a suppressor of apoptosis.
- Published in:
- Oncogene, 2000, v. 19, n. 54, p. 6386, doi. 10.1038/sj.onc.1204016
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- Publication type:
- Article
Dysregulated expression of β-catenin marks early neoplastic change in Apc mutant mice, but not all lesions arising in Msh2 deficient mice.
- Published in:
- Oncogene, 1999, v. 18, n. 51, p. 7219, doi. 10.1038/sj.onc.1203181
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- Publication type:
- Article
LKB1 loss of function studied in vivo
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- FEBS Letters, 2011, v. 585, n. 7, p. 958, doi. 10.1016/j.febslet.2011.01.019
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- Publication type:
- Article
Myc deletion rescues Apc deficiency in the small intestine.
- Published in:
- Nature, 2007, v. 446, n. 7136, p. 676, doi. 10.1038/nature05674
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- Publication type:
- Article
Ablation of ß1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.
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- Journal of Cell Biology, 2005, v. 171, n. 4, p. 717, doi. 10.1083/jcb.200503144
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- Publication type:
- Article
Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-20888-y
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- Publication type:
- Article
In vivo administration of O6-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine.
- Published in:
- Carcinogenesis, 2000, v. 21, n. 4, p. 593, doi. 10.1093/carcin/21.4.593
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- Publication type:
- Article
Manipulating the germline: its impact on the study of carcinogenesis.
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- Carcinogenesis, 2000, v. 21, n. 3, p. 435, doi. 10.1093/carcin/21.3.435
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- Publication type:
- Article
OncomiRdbB: a comprehensive database of microRNAs and their targets in breast cancer.
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- BMC Bioinformatics, 2014, v. 15, n. 1, p. 2, doi. 10.1186/1471-2105-15-15
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- Publication type:
- Article
Crypt stem cells as the cells-of-origin of intestinal cancer.
- Published in:
- Nature, 2009, v. 457, n. 7229, p. 608, doi. 10.1038/nature07602
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- Publication type:
- Article
Apc deficiency predisposes to renal carcinoma in the mouse.
- Published in:
- Oncogene, 2005, v. 24, n. 55, p. 8205, doi. 10.1038/sj.onc.1208956
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- Publication type:
- Article
Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells.
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- Oncogene, 2005, v. 24, n. 23, p. 3842, doi. 10.1038/sj.onc.1208533
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- Publication type:
- Article
p53 mediates a default programme of mammary gland involution in the absence of STAT3.
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- Oncogene, 2005, v. 24, n. 19, p. 3083, doi. 10.1038/sj.onc.1208512
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- Publication type:
- Article
PPARdstatus and Apc-mediated tumourigenesis in the mouse intestine.
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- Oncogene, 2004, v. 23, n. 55, p. 8992, doi. 10.1038/sj.onc.1208143
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- Publication type:
- Article
MBD4 deficiency does not increase mutation or accelerate tumorigenesis in mice lacking MMR.
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- Oncogene, 2004, v. 23, n. 33, p. 5693, doi. 10.1038/sj.onc.1207767
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- Publication type:
- Article
Single cell tracking reveals that Msh2 is a key component of an early-acting DNA damage-activated G2 checkpoint.
- Published in:
- Oncogene, 2003, v. 22, n. 48, p. 7642, doi. 10.1038/sj.onc.1206876
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- Publication type:
- Article
Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation.
- Published in:
- Nature Genetics, 2008, v. 40, n. 12, p. 1436, doi. 10.1038/ng.256
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- Publication type:
- Article
Deficiency of Mbd2 suppresses intestinal tumorigenesis.
- Published in:
- Nature Genetics, 2003, v. 34, n. 2, p. 145, doi. 10.1038/ng1155
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- Publication type:
- Article
Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine.
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- PLoS Genetics, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.pgen.1004453
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- Publication type:
- Article
<i>Cited1</i> Deficiency Suppresses Intestinal Tumorigenesis.
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- PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003638
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- Publication type:
- Article
Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo.
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- PLoS Genetics, 2010, v. 6, n. 1, p. 1, doi. 10.1371/journal.pgen.1000816
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- Publication type:
- Article
Apoptosis and carcinogenesis.
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- British Medical Bulletin, 1997, v. 53, n. 3, p. 554, doi. 10.1093/oxfordjournals.bmb.a011630
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- Publication type:
- Article
What are the best routes to effectively model human colorectal cancer?
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- Molecular Oncology, 2013, v. 7, n. 2, p. 178, doi. 10.1016/j.molonc.2013.02.006
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- Article
Author Correction: Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Author Correction: Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.
- Published in:
- 2020
- By:
- Publication type:
- Correction Notice
p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium.
- Published in:
- EMBO Molecular Medicine, 2010, v. 2, n. 11, p. 472, doi. 10.1002/emmm.201000101
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- Publication type:
- Article
Lkb1 and Pten Synergise to Suppress mTOR-Mediated Tumorigenesis and Epithelial-Mesenchymal Transition in the Mouse Bladder.
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- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016209
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- Publication type:
- Article
Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine.
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- PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004264
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- Publication type:
- Article
Brg1 is Required for Stem Cell Maintenance in the Murine Intestinal Epithelium in a Tissue-Specific Manner.
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- Stem Cells, 2013, v. 31, n. 11, p. 2457, doi. 10.1002/stem.1498
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- Publication type:
- Article
Evidence for a Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury.
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- Stem Cells, 2013, v. 31, n. 4, p. 776, doi. 10.1002/stem.1326
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- Publication type:
- Article
Mbd2 enables tumourigenesis within the intestine while preventing tumour‐promoting inflammation.
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- Journal of Pathology, 2018, v. 245, n. 3, p. 270, doi. 10.1002/path.5074
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- Publication type:
- Article
PTEN loss and activation of K‐RAS and β‐catenin cooperate to accelerate prostate tumourigenesis.
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- Journal of Pathology, 2017, v. 243, p. 442, doi. 10.1002/path.4977
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- Publication type:
- Article
PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
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- Journal of Pathology, 2017, v. 243, n. 4, p. 442, doi. 10.1002/path.4977
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- Publication type:
- Article
PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.
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- Journal of Pathology, 2014, v. 233, n. 1, p. 27, doi. 10.1002/path.4312
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- Publication type:
- Article
PTEN loss and KRAS activation cooperate in murine biliary tract malignancies.
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- Journal of Pathology, 2013, v. 230, n. 2, p. 165, doi. 10.1002/path.4189
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- Publication type:
- Article
WT1 and kidney failure.
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- Journal of Pathology, 2003, v. 200, n. 5, p. 667
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- Publication type:
- Article
Hepatic progenitor cells of biliary origin with liver repopulation capacity.
- Published in:
- Nature Cell Biology, 2015, v. 17, n. 8, p. 971, doi. 10.1038/ncb3203
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- Publication type:
- Article
3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
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- PLoS ONE, 2020, v. 14, n. 8, p. 1, doi. 10.1371/journal.pone.0235319
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- Publication type:
- Article
Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma.
- Published in:
- 2016
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- Publication type:
- journal article
Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis.
- Published in:
- Arthritis Research & Therapy, 2011, v. 13, n. 6, p. 3536, doi. 10.1186/ar3536
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- Publication type:
- Article
A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine.
- Published in:
- BMC Cancer, 2008, v. 8, p. 1, doi. 10.1186/1471-2407-8-162
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- Publication type:
- Article
Caspase-dependent proteolytic cleavage of STAT3α in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines.
- Published in:
- BMC Cancer, 2007, v. 7, p. 29, doi. 10.1186/1471-2407-7-29
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- Publication type:
- Article
PPARδ status and mismatch repair mediated neoplasia in the mouse intestine.
- Published in:
- BMC Cancer, 2006, v. 6, p. 113, doi. 10.1186/1471-2407-6-113
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- Publication type:
- Article