Works by Clapés, Pere

Results: 62

Nucleophile Promiscuity of Natural and Engineered Aldolases.

Published in:

ChemBioChem, 2018, v. 19, n. 13, p. 1353, doi. 10.1002/cbic.201800135

By:

Hernández, Karel;
Szekrenyi, Anna;
Clapés, Pere

Publication type:

Article

Unifying Scheme for the Biosynthesis of Acyl‐Branched Sugars: Extended Substrate Scope of Thiamine‐Dependent Enzymes.

Published in:

Angewandte Chemie, 2022, v. 134, n. 12, p. 1, doi. 10.1002/ange.202113405

By:

Steitz, Jan‐Patrick;
Krug, Leonhard;
Walter, Lydia;
Hernández, Karel;
Röhr, Caroline;
Clapés, Pere;
Müller, Michael

Publication type:

Article

Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products.

Published in:

Angewandte Chemie, 2018, v. 130, n. 32, p. 10310, doi. 10.1002/ange.201804831

By:

Junker, Sebastian;
Roldan, Raquel;
Joosten, Henk‐Jan;
Clapés, Pere;
Fessner, Wolf‐Dieter

Publication type:

Article

A dynamic view of enzyme catalysis.

Published in:

Journal of Molecular Modeling, 2008, v. 14, n. 8, p. 735

By:

Aurora Jiménez;
Pere Clapés;
Ramon Crehuet

Publication type:

Article

Expanding Synthetic Applications of Δ1‐Piperidine‐2‐carboxylate/Δ1‐pyrroline‐2‐carboxylate Reductase from Pseudomonas syringae (DpkAPsyrin). Biocatalytic Asymmetric Synthesis of (S,E)‐2‐hydroxy‐4‐arylbut‐3‐enoic Acid Derivatives

Published in:

Advanced Synthesis & Catalysis, 2024, v. 366, n. 4, p. 990, doi. 10.1002/adsc.202300953

By:

Moreno, Carlos J.;
Gittings, Samantha;
Schollmeyer, Dieter;
Joglar, Jesús;
Bujons, Jordi;
Hernández, Karel;
Clapés, Pere

Publication type:

Article

Biocatalytic Transamination of Aldolase‐Derived 3‐Hydroxy Ketones.

Published in:

Advanced Synthesis & Catalysis, 2023, v. 365, n. 9, p. 1485, doi. 10.1002/adsc.202300201

By:

Pickl, Mathias;
Ebner, Markus;
Gittings, Samantha;
Clapés, Pere;
Kroutil, Wolfgang

Publication type:

Article

Chemoenzymatic Production of Enantiocomplementary 2‐Substituted 3‐Hydroxycarboxylic Acids from l‐α‐Amino Acids.

Published in:

Advanced Synthesis & Catalysis, 2021, v. 363, n. 11, p. 2866, doi. 10.1002/adsc.202100145

By:

Pickl, Mathias;
Marín‐Valls, Roser;
Joglar, Jesús;
Bujons, Jordi;
Clapés, Pere

Publication type:

Article

Aldolase‐Catalyzed Asymmetric Synthesis of N‐Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes.

Published in:

Advanced Synthesis & Catalysis, 2019, v. 361, n. 11, p. 2673, doi. 10.1002/adsc.201801530

By:

Roldán, Raquel;
Hernández, Karel;
Joglar, Jesús;
Bujons, Jordi;
Parella, Teodor;
Fessner, Wolf‐Dieter;
Clapés, Pere

Publication type:

Article

Comparative study of the antimicrobial activity of bis(Nα-caproyl-l-arginine)-1,3-propanediamine dihydrochloride and chlorhexidine dihydrochloride against Staphylococcus aureus and Escherichia coli.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2006, v. 57, n. 4, p. 691, doi. 10.1093/jac/dkl012

By:

José A. Castillo;
Pere Clapés;
M. Rosa Infante;
Jaume Comas;
Ángeles Manresa

Publication type:

Article

Amino Acid-based Surfactants: Enzymatic Synthesis, Properties and Potential Applications.

Published in:

Biocatalysis & Biotransformation, 2002, v. 20, n. 4, p. 215, doi. 10.1080/10242420290004947

By:

Clapés, Pere;
Infante, María Rosa

Publication type:

Article

A Novel Activity of Immobilized Penicillin G Acylase: Removal of Benzyloxycarbonyl Amino Protecting Group.

Published in:

Biocatalysis & Biotransformation, 2000, v. 18, n. 3, p. 253, doi. 10.3109/10242420009015248

By:

Alvaro, Gregorio;
Feliu, Josep A.;
Caminal, Gloria;
López-santín, Josep;
Clapés, Pere

Publication type:

Article

Useful Methods in Enzymatic Synthesis of Peptides: A Comparative Study Focussing on Kinetically Controlled Synthesis of Ac-Phe-Ala-NH2 Catalyzed by α-Chymotrypsin.

Published in:

Biocatalysis & Biotransformation, 1999, v. 17, n. 5, p. 319, doi. 10.3109/10242429909015234

By:

Björup, Peter;
Adlercreutz, Patrick;
Clapés, Pere

Publication type:

Article

N-Protection of Amino Acid Derivatives Catalyzed by Immobilized Penicillin G Acylase.

Published in:

Biocatalysis & Biotransformation, 1996, v. 14, n. 4, p. 317, doi. 10.3109/10242429609110283

By:

Fit, Merc;
Capellas, Montserrat;
Benaiges, M. Dolors;
Caminal, Gloria;
Clapés, Pere;
Alvaro, Gregorio

Publication type:

Article

Influence of Water Activity and Support Material on the Enzymatic Synthesis of a Cck-8 Tripeptide Fragment.

Published in:

Biocatalysis & Biotransformation, 1996, v. 13, n. 3, p. 165, doi. 10.3109/10242429608997673

By:

Capellas, Montserrat;
Benaiges, M Dolors;
Caminal, Gloria;
González, Gloria;
López-Santín, Josep;
Clapés, Pere

Publication type:

Article

Effect of d-fagomine on excreted enterobacteria and weight gain in rats fed a high-fat high-sucrose diet.

Published in:

Obesity (19307381), 2014, v. 22, n. 4, p. 976, doi. 10.1002/oby.20640

By:

Ramos‐Romero, Sara;
Molinar‐Toribio, Eunice;
Gómez, Livia;
Pérez‐Jiménez, Jara;
Casado, Marta;
Clapés, Pere;
Piña, Benjamín;
Torres, Josep Lluís

Publication type:

Article

Asymmetric Self- and Cross-Aldol Reactions of Glycolaldehyde Catalyzed by.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 30, p. 5521, doi. 10.1002/anie.200902065

By:

Garrabou, Xavier;
Castillo, José A.;
Guérard-Hélaine, Christine;
Parella, Teodor;
Joglar, Jesús;
Lemaire, Marielle;
Clapés, Pere

Publication type:

Article

Enzymatic Peptide Synthesis in Organic Mediaa.

Published in:

Annals of the New York Academy of Sciences, 1990, v. 613, n. 1, p. 517, doi. 10.1111/j.1749-6632.1990.tb18211.x

By:

ADLERCREUTZ, PATRICK;
CLAPÉS, PERE;
MATTIASSON, BO

Publication type:

Article

Model-based optimization of the enzymatic aldol addition of propanal to formaldehyde: A first step towards enzymatic synthesis of 3-hydroxybutyric acid.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2019, v. 150, p. 140, doi. 10.1016/j.cherd.2019.06.025

By:

Česnik, Morana;
Sudar, Martina;
Roldan, Raquel;
Hernandez, Karel;
Parella, Teodor;
Clapés, Pere;
Charnock, Simon;
Vasić-Rački, Đurđa;
Findrik Blažević, Zvjezdana

Publication type:

Article

Unifying Scheme for the Biosynthesis of Acyl‐Branched Sugars: Extended Substrate Scope of Thiamine‐Dependent Enzymes.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 12, p. 1, doi. 10.1002/anie.202113405

By:

Steitz, Jan‐Patrick;
Krug, Leonhard;
Walter, Lydia;
Hernández, Karel;
Röhr, Caroline;
Clapés, Pere;
Müller, Michael

Publication type:

Article

Chemo-enzymatic synthesis of arginine-based gemini surfactants.

Published in:

Biotechnology & Bioengineering, 2000, v. 70, n. 3, p. 323, doi. 10.1002/1097-0290(20001105)70:3<323::AID-BIT9>3.0.CO;2-N

By:

Piera, Eulalia;
Infante, María Rosa;
Clapés, Pere

Publication type:

Article

Enzymatic synthesis of arginine-based cationic surfactants.

Published in:

Biotechnology & Bioengineering, 1999, v. 63, n. 3, p. 333, doi. 10.1002/(SICI)1097-0290(19990505)63:3<333::AID-BIT10>3.0.CO;2-G

By:

Clapés, Pere;
Morán, Carmen;
Infante, María Rosa

Publication type:

Article

Enzymatic condensation of cholecystokinin CCK-8 (4-6) and CCK-8 (7-8) peptide fragments in organic media.

Published in:

Biotechnology & Bioengineering, 1997, v. 56, n. 4, p. 456, doi. 10.1002/(SICI)1097-0290(19971120)56:4<456::AID-BIT11>3.0.CO;2-A

By:

Capellas, Montserrat;
Caminal, Gloria;
Gonzalez, Gloria;
López-Santín, Josep;
Clapés, Pere

Publication type:

Article

Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose-6-phosphate Aldolase.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 21, p. 5005, doi. 10.1002/chem.201701020

By:

Roldán, Raquel;
Sanchez‐Moreno, Israel;
Scheidt, Thomas;
Hélaine, Virgil;
Lemaire, Marielle;
Parella, Teodor;
Clapés, Pere;
Fessner, Wolf‐Dieter;
Guérard‐Hélaine, Christine

Publication type:

Article

Redesigning the Active Site of Transaldolase TalB from Escherichia coli: New Variants with Improved Affinity towards Nonphosphorylated Substrates.

Published in:

ChemBioChem, 2010, v. 11, n. 5, p. 681, doi. 10.1002/cbic.200900720

By:

Schneider, Sarah;
Gutiérrez, Mariana;
Sandalova, Tatyana;
Schneider, Gunter;
Clapés, Pere;
Sprenger, Georg A.;
Samland, Anne K.

Publication type:

Article

Biocatalytic synthesis, antimicrobial properties and toxicity studies of arginine derivative surfactants.

Published in:

Amino Acids, 2015, v. 47, n. 7, p. 1465, doi. 10.1007/s00726-015-1979-0

By:

Fait, M.;
Garrote, Graciela;
Clapés, Pere;
Tanco, Sebastian;
Lorenzo, Julia;
Morcelle, Susana

Publication type:

Article

Chemoenzymatic Synthesis and Antimicrobial and Haemolytic Activities of Amphiphilic Bis(phenylacetylarginine) Derivatives.

Published in:

ChemMedChem, 2006, v. 1, n. 10, p. 1091, doi. 10.1002/cmdc.200600148

By:

Castillo, José A.;
Infante, M. Rosa;
Manresa, Àngels;
Vinardell, M. Pilar;
Mitjans, Montserrat;
Clapés, Pere

Publication type:

Article

Disentangling Complex Mixtures of Compounds with Near-Identical 1H and 13C NMR Spectra using Pure Shift NMR Spectroscopy.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 21, p. 7682, doi. 10.1002/chem.201500521

By:

Castañar, Laura;
Roldán, Raquel;
Clapés, Pere;
Virgili, Albert;
Parella, Teodor

Publication type:

Article

Expedient Synthesis of C-Aryl Carbohydrates by Consecutive Biocatalytic Benzoin and Aldol Reactions.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 8, p. 3335, doi. 10.1002/chem.201406156

By:

Hernández, Karel;
Parella, Teodor;
Joglar, Jesús;
Bujons, Jordi;
Pohl, Martina;
Clapés, Pere

Publication type:

Article

Engineering the Donor Selectivity of D-Fructose-6-Phosphate Aldolase for Biocatalytic Asymmetric Cross-Aldol Additions of Glycolaldehyde.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 39, p. 12572, doi. 10.1002/chem.201403281

By:

Szekrenyi, Anna;
Soler, Anna;
Garrabou , Xavier;
Guérard ‐ Hélaine , Christine;
Parella, Teodor;
Joglar, Jesús;
Lemaire , Marielle;
Bujons, Jordi;
Clapés, Pere

Publication type:

Article

Titelbild: Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from <italic>E. Coli</italic> (Angew. Chem. 14/2018).

Published in:

Angewandte Chemie, 2018, v. 130, n. 14, p. 3581, doi. 10.1002/ange.201802275

By:

Hernández, Karel;
Joglar, Jesús;
Bujons, Jordi;
Parella, Teodor;
Clapés, Pere

Publication type:

Article

Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from <italic>E. Coli</italic>.

Published in:

Angewandte Chemie, 2018, v. 130, n. 14, p. 3645, doi. 10.1002/ange.201711289

By:

Hernández, Karel;
Joglar, Jesús;
Bujons, Jordi;
Parella, Teodor;
Clapés, Pere

Publication type:

Article

Intramolecular Benzoin Reaction Catalyzed by Benzaldehyde Lyase from Pseudomonas Fluorescens Biovar I.

Published in:

Angewandte Chemie, 2017, v. 129, n. 19, p. 5388, doi. 10.1002/ange.201702278

By:

Hernández, Karel;
Parella, Teodor;
Petrillo, Giovanna;
Usón, Isabel;
Wandtke, Claudia M.;
Joglar, Jesús;
Bujons, Jordi;
Clapés, Pere

Publication type:

Article

Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of α,α-Dialkyl-α-Amino Acids.

Published in:

Angewandte Chemie, 2015, v. 127, n. 10, p. 3056, doi. 10.1002/ange.201411484

By:

Hernandez, Karel;
Zelen, Igor;
Petrillo, Giovanna;
Usón, Isabel;
Wandtke, Claudia M.;
Bujons, Jordi;
Joglar, Jesús;
Parella, Teodor;
Clapés, Pere

Publication type:

Article

Cytotoxicity and enzymatic activity inhibition in cell lines treated with novel iminosugar derivatives.

Published in:

Glycoconjugate Journal, 2010, v. 27, n. 2, p. 277, doi. 10.1007/s10719-009-9276-3

By:

Padró, Mercè;
Castillo, José;
Gómez, Livia;
Joglar, Jesús;
Clapés, Pere;
Bolós, Carme

Publication type:

Article

Neoglycopeptide Synthesis and Purification in Multi-gram Scale: Preparation of O-(2,3,4,6-tetra- O-acetyl-β- D-galactopyranosyl)- Nα-fluoren-9-yl-methoxycarbonyl-hydroxyproline and Its Use in the Pilot-scale Synthesis of the Potent Analgesic Glycopeptide O1.5-β- D-galactopyranosyl[ DMet2, Hyp5]enkephalinamide

Published in:

Journal of Peptide Science, 1997, v. 3, n. 2, p. 99, doi. 10.1002/(SICI)1099-1387(199703)3:2<99::AID-PSC89>3.0.CO;2-F

By:

Torres, Josep Lluís;
Clapés, Pere

Publication type:

Article

Asymmetric assembly of aldose carbohydrates from formaldehyde and glycolaldehyde by tandem biocatalytic aldol reactions.

Published in:

Nature Chemistry, 2015, v. 7, n. 9, p. 724, doi. 10.1038/nchem.2321

By:

Szekrenyi, Anna;
Garrabou, Xavier;
Parella, Teodor;
Joglar, Jesús;
Bujons, Jordi;
Clapés, Pere

Publication type:

Article

Solid-Phase Synthesis of Glycopeptide Amides under Mild Conditions: Morphiceptin Analogues.

Published in:

Angewandte Chemie International Edition, 1990, v. 29, n. 3, p. 291, doi. 10.1002/anie.199002911

By:

Bardají, Eduard;
Torres, Josep L.;
Clapés, Pere;
Albericio, Fernando;
Barany, George;
Valencia, Gregorio

Publication type:

Article

Integrated Process for the Enzymatic Synthesis of the Octapeptide PhAcCCK-8.

Published in:

Biotechnology Progress, 2002, v. 18, n. 6, p. 1214, doi. 10.1021/bp0256465

By:

Fité, Mercè;
Clapés, Pere;
López-Santín, Josep;
Benaiges, M. Dolors;
Caminal, Glòria

Publication type:

Article

2-Keto-3-Deoxy- l-Rhamnonate Aldolase (YfaU) as Catalyst in Aldol Additions of Pyruvate to Amino Aldehyde Derivatives.

Published in:

Advanced Synthesis & Catalysis, 2017, v. 359, n. 12, p. 2090, doi. 10.1002/adsc.201700360

By:

Hernández, Karel;
Gómez, Ariadna;
Joglar, Jesús;
Bujons, Jordi;
Parella, Teodor;
Clapés, Pere

Publication type:

Article

Structure-Guided Engineering of D-Fructose-6-Phosphate Aldolase for Improved Acceptor Tolerance in Biocatalytic Aldol Additions.

Published in:

Advanced Synthesis & Catalysis, 2015, v. 357, n. 8, p. 1787, doi. 10.1002/adsc.201500073

By:

Soler, Anna;
Gutiérrez, Mariana L.;
Bujons, Jordi;
Parella, Teodor;
Minguillon, Cristina;
Joglar, Jesús;
Clapés, Pere

Publication type:

Article

L-Rhamnulose-1-phosphate Aldolase from Thermotoga maritima in Organic Synthesis: One-Pot Multistep Reactions for the Preparation of Imino- and Nitrocyclitols.

Published in:

Advanced Synthesis & Catalysis, 2015, v. 357, n. 8, p. 1951, doi. 10.1002/adsc.201500187

By:

Oroz ‐ Guinea, Isabel;
Hernández, Karel;
Camps Bres, Flora;
Guérard ‐ Hélaine, Christine;
Lemaire, Marielle;
Clapés, Pere;
García ‐ Junceda, Eduardo

Publication type:

Article

Sequential Biocatalytic Aldol Reactions in Multistep Asymmetric Synthesis: Pipecolic Acid, Piperidine and Pyrrolidine (Homo)Iminocyclitol Derivatives from Achiral Building Blocks.

Published in:

Advanced Synthesis & Catalysis, 2014, v. 356, n. 14/15, p. 3007, doi. 10.1002/adsc.201400453

By:

Soler, Anna;
Garrabou, Xavier;
Hernández, Karel;
Gutiérrez, Mariana L.;
Busto, Eduardo;
Bujons, Jordi;
Parella, Teodor;
Joglar, Jesús;
Clapés, Pere

Publication type:

Article

Current Trends in Asymmetric Synthesis with Aldolases.

Published in:

Advanced Synthesis & Catalysis, 2011, v. 353, n. 13, p. 2263, doi. 10.1002/adsc.201100236

By:

Clapés, Pere;
Garrabou, Xavier

Publication type:

Article

Redesign of the Phosphate Binding Site of.

Published in:

Advanced Synthesis & Catalysis, 2011, v. 353, n. 1, p. 89, doi. 10.1002/adsc.201000719

By:

Garrabou, Xavier;
Joglar, Jesús;
Parella, Teodor;
Crehuet, Ramon;
Bujons, Jordi;
Clapés, Pere

Publication type:

Article

Biocatalyzed Synthesis and Structural Characterization of Monoglucuronides of Hydroxytyrosol, Tyrosol, Homovanillic Alcohol, and 3-(4?-Hydroxyphenyl)propanol.

Published in:

Advanced Synthesis & Catalysis, 2006, v. 348, n. 15, p. 2155, doi. 10.1002/adsc.200606221

By:

Olha Khymenets;
Jesús Joglar;
Pere Clapés;
Teodor Parella;
María-Isabel Covas;
Rafael de la Torre

Publication type:

Article

Influence of the contact model and support characteristics on the partition constant for kinetically controlled synthesis of peptides.

Published in:

Journal of Chemical Technology & Biotechnology, 1989, v. 45, n. 4, p. 271, doi. 10.1002/jctb.280450404

By:

Clapés, Pere;
Mata-Alvarez, Joan;
Valencia, Gregorio;
Reig, Francesca;
Haro, Isabel;
García-Antón, José-María

Publication type:

Article

Continuous enzymatic synthesis of Z-kyotorphin amide in an enzyme-immobilized fixed-bed reactor.

Published in:

Journal of Chemical Technology & Biotechnology, 1989, v. 45, n. 3, p. 191, doi. 10.1002/jctb.280450304

By:

Clapés, Pere;
Mata-Alvarez, Joan;
Valencia, Gregorio;
Reig, Francesca;
Torres, Josep L.;
García-Antón, José-María

Publication type:

Article

Structure-Guided Minimalist Redesign of the L-Fuculose-1-Phosphate Aldolase Active Site: Expedient Synthesis of Novel Polyhydroxylated Pyrrolizidines and their Inhibitory Properties Against Glycosidases and Intestinal Disaccharidases.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 35, p. 10691, doi. 10.1002/chem.201000714

By:

Garrabou, Xavier;
Gómez, Livia;
Joglar, Jesús;
Gil, Sergi;
Parella, Teodor;
Bujons, Jordi;
Clapés, Pere

Publication type:

Article

Dihydroxyacetone Phosphate Aldolase Catalyzed Synthesis of Structurally Diverse Polyhydroxylated Pyrrolidine Derivatives and Evaluation of their Glycosidase Inhibitory Properties.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 30, p. 7310, doi. 10.1002/chem.200900838

By:

Calveras, Jordi;
Egido-Gabás, Meritxell;
Gómez, Livia;
Casas, Josefina;
Parella, Teodor;
Joglar, Jesús;
Bujons, Jordi;
Clapés, Pere

Publication type:

Article

D-Fructose-6-phosphate Aldolase in Organic Synthesis: Cascade Chemical-Enzymatic Preparation of Sugar-Related Polyhydroxylated Compounds.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 15, p. 3808, doi. 10.1002/chem.200802532

By:

Concia, Alda Lisa;
Lozano, Carles;
Castillo, José A.;
Parella, Teodor;
Joglar, Jesús;
Clapés, Pere

Publication type:

Article