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Anti-Amyloid-β Single-Chain Antibody Brain Delivery Via AAV Reduces Amyloid Load But May Increase Cerebral Hemorrhages in an Alzheimer's Disease Mouse Model.
Published in:
Journal of Alzheimer's Disease, 2011, v. 27, n. 1, p. 23, doi. 10.3233/JAD-2011-110230
By:
- Kou, Jinghong;
- Kim, HongDuck;
- Pattanayak, Abhinandan;
- Song, Min;
- Lim, Jeong-Eun;
- Taguchi, Hiroaki;
- Paul, Sudhir;
- Cirrito, John R.;
- Ponnazhagan, Selvarangan;
- Fukuchi, Ken-ichiro
Publication type:
Article
Anti-Amyloid-β Single-Chain Antibody Brain Delivery Via AAV Reduces Amyloid Load But May Increase Cerebral Hemorrhages in an Alzheimer's Disease Mouse Model.
Published in:
2011
By:
- Kou J;
- Kim H;
- Pattanayak A;
- Song M;
- Lim JE;
- Taguchi H;
- Paul S;
- Cirrito JR;
- Ponnazhagan S;
- Fukuchi K;
- Kou, Jinghong;
- Kim, HongDuck;
- Pattanayak, Abhinandan;
- Song, Min;
- Lim, Jeong-Eun;
- Taguchi, Hiroaki;
- Paul, Sudhir;
- Cirrito, John R;
- Ponnazhagan, Selvarangan;
- Fukuchi, Ken-ichiro
Publication type:
journal article
Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice.
Published in:
2009
By:
- Cao C;
- Cirrito JR;
- Lin X;
- Wang L;
- Verges DK;
- Dickson A;
- Mamcarz M;
- Zhang C;
- Mori T;
- Arendash GW;
- Holtzman DM;
- Potter H;
- Cao, Chuanhai;
- Cirrito, John R;
- Lin, Xiaoyang;
- Wang, Li;
- Wang, Lilly;
- Verges, Deborah K;
- Dickson, Alexander;
- Mamcarz, Malgorzata
Publication type:
journal article
Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice.
Published in:
Journal of Alzheimer's Disease, 2009, v. 17, n. 3, p. 681, doi. 10.3233/JAD-2009-1071
By:
- Chuanhai Cao;
- Cirrito, John R.;
- Xiaoyang Lin;
- Wang, Lilly;
- Verges, Deborah K;
- Dickson, Alexander;
- Mamcarz, Malgorzata;
- Chi Zhang;
- Mori, Takashi;
- Arendash, Gary W.;
- Holtzman, David M.;
- Potter, Huntington
Publication type:
Article
Sex-dependent effects of acute stress on amyloid-β in male and female mice.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 6, p. 2268, doi. 10.1093/brain/awad052
By:
- Edwards, Hannah M;
- Wallace, Clare E;
- Gardiner, Woodrow D;
- Doherty, Brookelyn M;
- Harrigan, Ryan T;
- Yuede, Kayla M;
- Yuede, Carla M;
- Cirrito, John R
Publication type:
Article
Aqp4 stop codon readthrough facilitates amyloid-β clearance from the brain.
Published in:
2022
By:
- Sapkota, Darshan;
- Florian, Colin;
- Doherty, Brookelyn M;
- White, Kelli M;
- Reardon, Kate M;
- Ge, Xia;
- Garbow, Joel R;
- Yuede, Carla M;
- Cirrito, John R;
- Dougherty, Joseph D
Publication type:
journal article
Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity.
Published in:
2016
By:
- Bales, Kelly R.;
- O'Neill, Sharon M.;
- Pozdnyakov, Nikolay;
- Feng Pan;
- Caouette, David;
- YeQing Pi;
- Wood, Kathleen M.;
- Volfson, Dmitri;
- Cirrito, John R.;
- Han, Byung-Hee;
- Johnson, Andrew W.;
- Zipfel, Gregory J.;
- Samad, Tarek A.;
- Pan, Feng;
- Pi, YeQing
Publication type:
journal article
In Vivo Assessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life.
Published in:
Journal of Neuroscience, 2003, v. 23, n. 26, p. 8844, doi. 10.1523/JNEUROSCI.23-26-08844.2003
By:
- Cirrito, John R.;
- May, Patrick C.;
- O'Dell, Mark A.;
- Taylor, Jennie W.;
- Parsadanian, Maia;
- Cramer, Jeffrey W.;
- Audia, James E.;
- Nissen, Jeffrey S.;
- Bales, Kelly R.;
- Paul, Steven M.;
- DeMattos, Ronald B.;
- Holtzman, David M.
Publication type:
Article
circRNAs mediate the effect of chronic lysosomal dysfunction on Alzheimer's disease pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072168
By:
- Romero, Skarleth Cardenas;
- Eteleeb, Abdallah M;
- Nykanen, Niko‐Petteri;
- O'Dell, Kevin;
- Nunez, Marie;
- Harari, Oscar;
- Cirrito, John R;
- Sands, Mark;
- Benitez, Bruno A.
Publication type:
Article
Targeting Substance P Pathway as an Emerging Novel Therapeutic Mechanism for Modulating Amyloid Beta in APP/PS1 Mouse Model.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.062335
By:
- Yuede, Carla M;
- Cirrito, John R;
- Johns, Stefanie;
- Knie, Robb
Publication type:
Article
Defining the role of PLD3 in Alzheimer disease pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054611
By:
- Rosene, Matthew J;
- Hsu, Simon;
- Martinez, Rita;
- Norton, Joanne;
- Yan, Ping;
- Cirrito, John R;
- Lee, Jin‐Moo;
- Cuervo, Ana Maria;
- Goate, Alison M.;
- Cruchaga, Carlos;
- Karch, Celeste M.
Publication type:
Article
DNAJC5 affects the endo‐lysosomal pathway, APP processing, and AD pathology in vitro and in vivo.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054177
By:
- Nykanen, Niko;
- Wang, Zhaohua;
- Davis, Todd A;
- Nunez, Marie;
- O'Dell, Kevin;
- Cirrito, John R;
- Sands, Mark;
- Benitez, Bruno A.
Publication type:
Article
The impacts of menopause on a mouse model of co‐morbid metabolic syndrome and Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051172
By:
- Abi‐Ghanem, Charly;
- Salinero, Abigail E;
- Gannon, Olivia J;
- Riccio, David;
- Mansour, Febronia;
- Kelly, Richard D;
- Kordit, David;
- Wang, Matthew;
- Kyaw, Nyi‐Rein;
- Cirrito, John R;
- Zuloaga, Kristen L
Publication type:
Article
Defining the role of PLD3 in Alzheimer's disease pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058730
By:
- Rosene, Matthew J;
- Hsu, Simon;
- Martinez, Rita;
- Norton, Joanne;
- Yan, Ping;
- Cirrito, John R;
- Lee, Jin‐Moo;
- Cuervo, Ana Maria;
- Goate, Alison M.;
- Cruchaga, Carlos;
- Karch, Celeste M.
Publication type:
Article
P3‐026: DIFFERENTIAL EFFECT OF PROSPECTIVE ESCITALOPRAM DECREASE ON LONGITUDINAL CSF AB CONCENTRATION IN AMYLOID (+) VERSUS AMYLOID (‐) COGNITIVELY NORMAL ELDERLY INDIVIDUALS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1074, doi. 10.1016/j.jalz.2018.06.1381
By:
- Sheline, Yvette I.;
- Snider, B. Joy;
- Shinohara, Russell T.;
- Fagan, Anne M.;
- Waligorska, Teresa;
- Aselcioglu, Irem;
- Kristin, Linn;
- Cirrito, John R.;
- Shaw, Leslie M.
Publication type:
Article
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.
Published in:
2005
By:
- Cirrito, John R.;
- Deane, Rashid;
- Fagan, Anne M.;
- Spinner, Michael L.;
- Parsadanian, Maia;
- Finn, Mary Beth;
- Hong Jiang;
- Prior, Julie L.;
- Sagare, Abhay;
- Bales, Kelly R.;
- Paul, Steven M.;
- Zlokovic, Berislav V.;
- Piwnica-Worms, David;
- Holtzman, David M.;
- Jiang, Hong
Publication type:
journal article
Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.
Published in:
2005
By:
- Brendza, Robert P.;
- Bacskai, Brian J.;
- Cirrito, John R.;
- Simmons, Kelly A.;
- Skoch, Jesse M.;
- Klunk, William E.;
- Mathis, Chester A.;
- Bales, Kelly R.;
- Paul, Steven M.;
- Hyman, Bradley T.;
- Holtzman, David M.
Publication type:
journal article
PHOSPHOLIPASE D3 CONTRIBUTES TO ALZHEIMER’S DISEASE RISK VIA DISRUPTION OF Aβ CLEARANCE THROUGH THE LYSOSOME.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P602, doi. 10.1016/j.jalz.2017.07.248
By:
- Karch, Celeste;
- Hsu, Simon;
- Martinez, Rita;
- Norton, Joanne;
- Cirrito, John R.;
- Lee, Jin-Moo;
- Cuervo, Maria;
- Cruchaga, Carlos;
- Goate, Alison
Publication type:
Article
INHIBITING GLUCOCORTICOID RECEPTOR DIMERIZATION BLOCKS EFFECTS OF ACUTE STRESS ON Aβ IN FEMALE MICE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P308, doi. 10.1016/j.jalz.2017.06.237
By:
- Yuede, Carla M.;
- Wallace, Clare E.;
- Edwards, Hannah M.;
- Yuede, Kayla M.;
- Davis, Todd A.;
- Cirrito, John R.
Publication type:
Article
PROSPECTIVE ESCITALOPRAM DECREASES LONGITUDINAL CSF Aβ CONCENTRATION IN COGNITIVELY NORMAL ELDERLY SUBJECTS: A RANDOMIZED DOSE FINDING STUDY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1570, doi. 10.1016/j.jalz.2017.07.731
By:
- Sheline, Yvette I.;
- Snider, B. Joy;
- Shinohara, Russell T.;
- Fagan, Anne M.;
- Waligorska, Teresa;
- Aselcioglu, Irem;
- Kristin, Linn;
- Satchell, Emma K.;
- Cirrito, John R.;
- Shaw, Leslie M.
Publication type:
Article
PHOSPHATASE ACTIVITY DURING SLEEP/WAKE CYCLES REGULATES APP PROCESSING AND BRAIN ISF AMYLOID-β LEVELS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P312, doi. 10.1016/j.jalz.2017.06.249
By:
- Cirrito, John R.;
- Wallace, Clare E.;
- Edwards, Hannah M.
Publication type:
Article
ESCITALOPRAM DECREASES LONGITUDINAL CSF ABETA CONCENTRATION IN COGNITIVELY NORMAL SUBJECTS AGE 60-85.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P199, doi. 10.1016/j.jalz.2016.06.349
By:
- Sheline, Yvette I.;
- Snider, B. Joy;
- Korecka, Magdalena;
- Shinohara, Russell T.;
- Fagan, Anne M.;
- Mikkelsen, Eli J.V.;
- Satchell, Emma K.;
- Cirrito, John R.;
- Shaw, Leslie M.
Publication type:
Article
TREM2-MEDIATED EARLY RESPONSE BY RESIDENT MICROGLIA LIMITS DIFFUSION AND TOXICITY OF AMYLOID PLAQUES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P241, doi. 10.1016/j.jalz.2016.06.431
By:
- Wang, Yaming;
- Ulland, Tyler;
- Ulrich, Jason D.;
- Song, Wilbur;
- Yuan, Peng;
- Mahan, Thomas E.;
- Shi, Yang;
- Gilfillan, Susan;
- Cella, Marina;
- DeMattos, Ronald B.;
- Grutzendler, Jaime;
- Cirrito, John R.;
- Holtzman, David M.;
- Colonna, Marco
Publication type:
Article
Activated astrocytes suppress amyloid plaque pathogenesis in APP/PS1 mice
Published in:
2009
By:
- Kraft, Andrew W.;
- Hu, Xiaoyan;
- Yan, Ping;
- Xiao, Qingli;
- Holmes, Brandon B.;
- Wilhelmsson, Ulrika;
- Cirrito, John R.;
- Holtzman, David M.;
- Pekny, Milos;
- Lee, Jin-Moo
Publication type:
Abstract
Synaptic-dependent release of amyloid-beta in vivo
Published in:
2009
By:
- Cirrito, John R.
Publication type:
Abstract
P4-268: APP endocytosis is required for synaptic-dependent release of amyloid-beta in vivo
Published in:
2008
By:
- Cirrito, John R.;
- Stewart, Floy R.;
- Mennerick, Steven;
- Holtzman, David M.
Publication type:
Abstract
O1-03-05: Dynamics of compact plaque growth in APP/PS1 mice
Published in:
2008
By:
- Lee, Jin-Moo;
- Bero, Adam;
- Cirrito, John R.;
- Hu, Xiaoyan;
- Gonzales, Ernesto;
- Perez, Robert;
- Xiao, Qingli;
- Holtzman, David M.;
- Yan, Ping
Publication type:
Abstract
Real-time environmental surveillance of SARS-CoV-2 aerosols.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39419-z
By:
- Puthussery, Joseph V.;
- Ghumra, Dishit P.;
- McBrearty, Kevin R.;
- Doherty, Brookelyn M.;
- Sumlin, Benjamin J.;
- Sarabandi, Amirhossein;
- Mandal, Anushka Garg;
- Shetty, Nishit J.;
- Gardiner, Woodrow D.;
- Magrecki, Jordan P.;
- Brody, David L.;
- Esparza, Thomas J.;
- Bricker, Traci L.;
- Boon, Adrianus C. M.;
- Yuede, Carla M.;
- Cirrito, John R.;
- Chakrabarty, Rajan K.
Publication type:
Article
Exercise Training Results in Lower Amyloid Plaque Load and Greater Cognitive Function in an Intensity Dependent Manner in the Tg2576 Mouse Model of Alzheimer's Disease.
Published in:
Brain Sciences (2076-3425), 2020, v. 10, n. 2, p. 88, doi. 10.3390/brainsci10020088
By:
- Thomas, Riya;
- Zimmerman, Scott D.;
- Yuede, Kayla M.;
- Cirrito, John R.;
- Tai, Leon M.;
- Timson, Benjamin F.;
- Yuede, Carla M.
Publication type:
Article
Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 34, p. 10706, doi. 10.1523/JNEUROSCI.2637-09.2009
By:
- Ping Yan;
- Bero, Adam W.;
- Cirrito, John R.;
- Qingli Xiao;
- Xiaoyan Hu;
- Yan Wang;
- Gonzales, Ernesto;
- Holtzman, David M.;
- Jin-Moo Lee
Publication type:
Article
Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid-β Peptide, Partial Restoration via γ-Secretase Inhibition.
Published in:
Journal of Neuroscience, 2008, v. 28, n. 50, p. 13542, doi. 10.1523/JNEUROSCI.4686-08.2008
By:
- Byung Hee Han;
- Meng-liang Zhou;
- Abousaleh, Fadi;
- Brendza, Robert P.;
- Dietrich, Hans H.;
- Koenigsknecht-Talboo, Jessica;
- Cirrito, John R.;
- Milner, Eric;
- Holtzman, David M.;
- Zipfel, Gregory J.
Publication type:
Article
Matrix Metalloproteinases Expressed by Astrocytes Mediate Extracellular Amyloid-β Peptide Catabolism.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 43, p. 10939, doi. 10.1523/JNEUROSCI.2085-06.2006
By:
- Ke-Jie Yin;
- Cirrito, John R.;
- Ping Yan;
- Xiaoyun Hu;
- Qingli Xiao;
- Xiaoou Pan;
- Bateman, Randall;
- Haowei Song;
- Fong-Fu Hsu;
- Turk, John;
- Jan Xu;
- Hsu, Chung Y.;
- Mills, Jason C.;
- Holtzman, David M.;
- Jin-Moo Lee
Publication type:
Article
Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice.
Published in:
FASEB Journal, 2013, v. 27, n. 1, p. 187, doi. 10.1096/fj.12-208660
By:
- Kraft, Andrew W.;
- Xiaoyan Hu;
- Hyejin Yoon;
- Ping Yan;
- Qingli Xiao;
- Yan Wang;
- So Chon Gil;
- Brown, Jennifer;
- Wilhelmsson, Ulrika;
- Restivo, Jessica L.;
- Cirrito, John R.;
- Holtzman, David M.;
- Jungsu Kim;
- Pekny, Milos;
- Jin-Moo Lee
Publication type:
Article
β-Secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic mice.
Published in:
FASEB Journal, 2011, v. 25, n. 2, p. 775, doi. 10.1096/fj.10-167213
By:
- Wan-Pin Chang;
- Xiangping Huang;
- Downs, Deborah;
- Cirrito, John R.;
- Koelsch, Gerald;
- Holtzman, David M.;
- Ghosh, Arun K.;
- Tang, Jordan
Publication type:
Article
Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia.
Published in:
Annals of Clinical & Translational Neurology, 2022, v. 9, n. 2, p. 106, doi. 10.1002/acn3.51482
By:
- Miller, Rebecca L.;
- Dhavale, Dhruva D.;
- O'Shea, Jennifer Y.;
- Andruska, Kristin M.;
- Liu, Jialu;
- Franklin, Erin E.;
- Buddhala, Chandana;
- Loftin, Susan K.;
- Cirrito, John R.;
- Perrin, Richard J.;
- Cairns, Nigel J.;
- Campbell, Meghan C.;
- Perlmutter, Joel S.;
- Kotzbauer, Paul T.
Publication type:
Article
Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer’s disease.
Published in:
Science Translational Medicine, 2016, v. 8, n. 332, p. 1, doi. 10.1126/scitranslmed.aad3650
By:
- Chia-Chen Liu;
- Na Zhao;
- Yu Yamaguchi;
- Cirrito, John R.;
- Takahisa Kanekiyo;
- Holtzman, David M.;
- Guojun Bu
Publication type:
Article
Comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice".
Published in:
Science Translational Medicine, 2014, v. 6, n. 268, p. 1, doi. 10.1126/scitranslmed.3010053
By:
- Emilsson, Johan Fredrik;
- Andreasson, Ulf;
- Blennow, Kaj;
- Eriksson, Elias;
- Zetterberg, Henrik;
- Sheline, Yvette I.;
- West, Tim;
- Yarasheski, Kevin;
- Jasielec, Mateusz S.;
- Hettinger, Jane C.;
- Tripoli, Danielle L.;
- Chengjie Xiong;
- Frederiksen, Christine;
- Grzelak, Monica V.;
- Bateman, Randall J.;
- Morris, John C.;
- Jin-Moo Lee;
- Cirrito, John R.
Publication type:
Article
Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls.
Published in:
2013
By:
- Esparza TJ;
- Zhao H;
- Cirrito JR;
- Cairns NJ;
- Bateman RJ;
- Holtzman DM;
- Brody DL;
- Esparza, Thomas J;
- Zhao, Hanzhi;
- Cirrito, John R;
- Cairns, Nigel J;
- Bateman, Randall J;
- Holtzman, David M;
- Brody, David L
Publication type:
journal article
Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls.
Published in:
Annals of Neurology, 2013, v. 73, n. 1, p. 104, doi. 10.1002/ana.23748
By:
- Esparza, Thomas J.;
- Zhao, Hanzhi;
- Cirrito, John R.;
- Cairns, Nigel J.;
- Bateman, Randall J.;
- Holtzman, David M.;
- Brody, David L.
Publication type:
Article
Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.
Published in:
Journal of Neurochemistry, 2021, v. 156, n. 5, p. 658, doi. 10.1111/jnc.15260
By:
- Yuede, Carla M.;
- Wallace, Clare E.;
- Davis, Todd A.;
- Gardiner, Woodrow D.;
- Hettinger, Jane C.;
- Edwards, Hannah M.;
- Hendrix, Rachel D.;
- Doherty, Brookelyn M.;
- Yuede, Kayla M.;
- Burstein, Ethan S.;
- Cirrito, John R.
Publication type:
Article
Microbiosensor for Alzheimer's disease diagnostics: detection of amyloid beta biomarkers.
Published in:
Journal of Neurochemistry, 2012, v. 122, n. 2, p. 374, doi. 10.1111/j.1471-4159.2012.07709.x
By:
- Prabhulkar, Shradha;
- Piatyszek, Rudolph;
- Cirrito, John R.;
- Wu, Ze-Zhi;
- Li, Chen-Zhong
Publication type:
Article
Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus.
Published in:
2014
By:
- Stukas, Sophie;
- Robert, Jerome;
- Lee, Michael;
- Kulic, Iva;
- Carr, Michael;
- Tourigny, Katherine;
- Fan, Jianjia;
- Namjoshi, Dhananjay;
- Lemke, Kalistyne;
- DeValle, Nicole;
- Chan, Jeniffer;
- Wilson, Tammy;
- Wilkinson, Anna;
- Chapanian, Rafi;
- Kizhakkedathu, Jayachandran N.;
- Cirrito, John R.;
- Oda, Michael N.;
- Wellington, Cheryl L.
Publication type:
journal article
An Antidepressant Decreases CSF Aβ Production in Healthy Individuals and in Transgenic AD Mice.
Published in:
Science Translational Medicine, 2014, v. 6, n. 236, p. 1, doi. 10.1126/scitranslmed.3008169
By:
- Sheline, Yvette I.;
- West, Tim;
- Yarasheski, Kevin;
- Swarm, Robert;
- Jasielec, Mateusz S.;
- Fisher, Jonathan R.;
- Ficker, Whitney D.;
- Ping Yan;
- Xiong, Chengjie;
- Frederiksen, Christine;
- Grzelak, Monica V.;
- Chott, Robert;
- Bateman, Randall J.;
- Morris, John C.;
- Mintun, Mark A.;
- Jin-Moo Lee;
- Cirrito, John R.
Publication type:
Article
Neuronal activity regulates the regional vulnerability to amyloid-β deposition.
Published in:
Nature Neuroscience, 2011, v. 14, n. 6, p. 750, doi. 10.1038/nn.2801
By:
- Bero, Adam W.;
- Ping Yan;
- Jee Hoon Roh;
- Cirrito, John R.;
- Stewart, Floy R.;
- Raichle, Marcus E.;
- Jin-Moo Lee;
- Holtzman, David M.
Publication type:
Article
AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model.
Published in:
Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0256-6
By:
- Hettinger, Jane C.;
- Lee, Hyo;
- Bu, Guojun;
- Holtzman, David M.;
- Cirrito, John R.
Publication type:
Article
Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo.
Published in:
Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0112-5
By:
- Fisher, Jonathan R.;
- Wallace, Clare E.;
- Tripoli, Danielle L.;
- Sheline, Yvette I.;
- Cirrito, John R.
Publication type:
Article
In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis.
Published in:
Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-13
By:
- Ulrich, Jason D.;
- Burchett, Jack M.;
- Restivo, Jessica L.;
- Schuler, Dorothy R;
- Verghese, Philip B.;
- Mahan, Thomas E.;
- Landreth, Gary E.;
- Castellano, Joseph M.;
- Jiang, Hong;
- Cirrito, John R.;
- Holtzman, David M.
Publication type:
Article
ApoE mimetic peptide decreases AΒ production in vitro and in vivo.
Published in:
Molecular Neurodegeneration, 2010, v. 5, p. 16, doi. 10.1186/1750-1326-5-16
By:
- Minami, S. Sakura;
- Cordova, Antoinette;
- Cirrito, John R.;
- Tesoriero, Joseph A.;
- Babus, Lenard W.;
- Davis, Gary C.;
- Dakshanamurthy, Sivanesan;
- Turner, R. Scott;
- Pak, Daniel T. S.;
- Rebeck, G. William;
- Paige, Mikell;
- Hyang-Sook Hoe
Publication type:
Article
Implications of Oligomeric Amyloid-Beta (oAβ42) Signaling through α7β2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline.
Published in:
Journal of Neuroscience, 2021, v. 41, n. 3, p. 555, doi. 10.1523/JNEUROSCI.0876-20.2020
By:
- George, Andrew A.;
- Vieira, Jaime M.;
- Xavier-Jackson, Cameron;
- Gee, Michael T.;
- Cirrito, John R.;
- Bimonte-Nelson, Heather A.;
- Picciotto, Marina R.;
- Lukas, Ronald J.;
- Whiteaker, Paul
Publication type:
Article
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter.
Published in:
2023
By:
- LaBarbera, Kelsie M.;
- Sheline, Yvette I.;
- Izzo, Nicholas J.;
- Yuede, Carla M.;
- Waybright, Lora;
- Yurko, Raymond;
- Edwards, Hannah M.;
- Gardiner, Woodrow D.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Börjesson-Hanson, Anne;
- Morgan, Roger;
- Davis, Charles S.;
- Guttendorf, Robert J.;
- Schneider, Lon S.;
- DeKosky, Steven;
- LeVine III, Harry;
- Grundman, Michael;
- Caggiano, Anthony O.;
- Cirrito, John R.
Publication type:
Abstract

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