Works matching AU Cines, Douglas B.

Results: 44

Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component on infected cells.

Published in:

Nature, 1984, v. 309, n. 5969, p. 633, doi. 10.1038/309633a0

By:

Friedman, Harvey M.;
Cohen, Gary H.;
Eisenberg, Roselyn J.;
Seidel, Cynthia A.;
Cines, Douglas B.

Publication type:

Article

Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes.

Published in:

Nature Biotechnology, 2003, v. 21, n. 8, p. 891, doi. 10.1038/nbt846

By:

Murciano, Juan-Carlos;
Medinilla, Sandra;
Eslin, Donald;
Atochina, Elena;
Cines, Douglas B;
Muzykantov, Vladimir R

Publication type:

Article

Platelet-Specific Chemokines Contribute to the Pathogenesis of Acute Lung Injury.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2017, v. 56, n. 2, p. 261, doi. 10.1165/rcmb.2015-0245OC

By:

Bdeir, Khalil;
Gollomp, Kandace;
Stasiak, Marta;
Junjie Mei;
Papiewska-Pajak, Izabela;
Guohua Zhao;
Worthen, G. Scott;
Cines, Douglas B.;
Poncz, Mortimer;
Kowalska, M. Anna

Publication type:

Article

Urokinase Plasminogen Activator Regulates Pulmonary Arterial Contractility and Vascular Permeability in Mice.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2011, v. 45, n. 5, p. 1015, doi. 10.1165/rcmb.2010-0302OC

By:

Nassar, Taher;
Yarovoi, Serge;
Fanne, Rami Abu;
Waked, Otailah;
Allen, Timothy C.;
Idell, Steven;
Cines, Douglas B.;
Higazi, Abd Al-Roof

Publication type:

Article

Regulation of Airway Contractility by Plasminogen Activators through N-Methyl-D-Aspartate Receptor-1.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2010, v. 43, n. 6, p. 703, doi. 10.1165/rcmb.2009-0257OC

By:

Nassa, Taher;
Yarovoi, Serge;
Fanne, Rami Abu;
Akkawi, Sa'ed;
Jammal, Mahmud;
Allen, Timothy Craig;
Idell, Steven;
Cines, Douglas B.;
Abd Al-Roof Higazi

Publication type:

Article

Thrombocytopenia following Pfizer and Moderna SARS‐CoV‐2 vaccination.

Published in:

American Journal of Hematology, 2021, v. 96, n. 5, p. 534, doi. 10.1002/ajh.26132

By:

Lee, Eun‐Ju;
Cines, Douglas B.;
Gernsheimer, Terry;
Kessler, Craig;
Michel, Marc;
Tarantino, Michael D.;
Semple, John W.;
Arnold, Donald M.;
Godeau, Bertrand;
Lambert, Michele P.;
Bussel, James B.

Publication type:

Article

Clinical trial opportunities in hemostasis and thrombosis: NHBLI State-of-the-science symposium.

Published in:

American Journal of Hematology, 2012, v. 87, n. 2, p. 235, doi. 10.1002/ajh.22225

By:

Cines, Douglas B.;
Blajchman, Morris A.;
High, Katherine A.;
Bussel, James B.

Publication type:

Article

Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis.

Published in:

PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0231582

By:

Higazi, Mohamed;
Abdeen, Suhair;
Abu-Fanne, Rami;
Heyman, Samuel N.;
Masarwy, Aseel;
Bdeir, Khalil;
Maraga, Emad;
Cines, Douglas B.;
Higazi, Abd Al-Roof

Publication type:

Article

COVID-19-associated Acute Respiratory Distress Syndrome Clarified: A Vascular Endotype?

Published in:

2020

By:

Mangalmurti, Nilam S.;
Reilly, John P.;
Cines, Douglas B.;
Meyer, Nuala J.;
Hunter, Christopher A.;
Vaughan, Andrew E.

Publication type:

Letter

Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia.

Published in:

2017

By:

Hayes, Vincent;
Johnston, Ian;
Arepally, Gowthami M.;
McKenzie, Steven E.;
Cines, Douglas B.;
Rauova, Lubica;
Poncz, Mortimer

Publication type:

journal article

A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation.

Published in:

2016

By:

Fuentes, Rudy E.;
Zaitsev, Sergei;
Ahn, Hyun Sook;
Hayes, Vincent;
Kowalska, M. Anna;
Lambert, Michele P.;
Wang, Yuhuan;
Siegel, Donald L.;
Bougie, Daniel W.;
Aster, Richard H.;
Myers, Daniel D.;
Stepanova, Victoria;
Cines, Douglas B.;
Muzykantov, Vladimir R.;
Poncz, Mortimer

Publication type:

journal article

Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. N.PAG, doi. 10.1038/s41598-022-19850-w

By:

Le, Hoa T.;
Golla, Kalyan;
Karimi, Ryan;
Hughes, Michael R.;
Lakschevitz, Flavia;
Cines, Douglas B.;
Kowalska, M. Anna;
Poncz, Mortimer;
McNagny, Kelly M.;
Häkkinen, Lari;
Kim, Hugh

Publication type:

Article

tPA variant tPA-A<sup>296-299</sup> Prevents impairment of cerebral autoregulation and necrosis of hippocampal neurons after stroke by inhibiting upregulation of ET-1.

Published in:

Journal of Neuroscience Research, 2018, v. 96, n. 1, p. 128, doi. 10.1002/jnr.24112

By:

Armstead, William M.;
Hekierski, Hugh;
Yarovoi, Serge;
Higazi, Abd Al‐Roof;
Cines, Douglas B.

Publication type:

Article

Detection of endothelial cell-reactive immunoglobulin in patients with anti-phospholipid antibodies.

Published in:

British Journal of Haematology, 1991, v. 79, n. 4, p. 595, doi. 10.1111/j.1365-2141.1991.tb08087.x

By:

McCrae, Keith R.;
DeMichele, Angela;
Samuels, Philip;
Roth, Denise;
Kuo, Alice;
Meng, Qiang-hua;
Rauch, Joyce;
Cines, Douglas B.

Publication type:

Article

Danazol treatment of myelodysplastic syndromes.

Published in:

British Journal of Haematology, 1991, v. 77, n. 4, p. 502, doi. 10.1111/j.1365-2141.1991.tb08617.x

By:

Stadtmauer, Edward A.;
Cassileth, Peter A.;
Edelstein, Marian;
Abrahm, Janet;
Schreiber, Alan D.;
Nowell, Peter C.;
Cines, Douglas B.

Publication type:

Article

Menstrual cyclic thrombocytopenia.

Published in:

British Journal of Haematology, 1989, v. 71, n. 4, p. 519, doi. 10.1111/j.1365-2141.1989.tb06312.x

By:

Tomer, Aaron;
Schreiber, Alan D.;
McMillan, Robert;
Cines, Douglas B.;
Burstein, Samuel A.;
Thiessen, A. Robert;
Harker, Laurence A.

Publication type:

Article

Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier.

Published in:

2010

By:

Bdeir K;
Higazi AA;
Kulikovskaya I;
Christofidou-Solomidou M;
Vinogradov SA;
Allen TC;
Idell S;
Linzmeier R;
Ganz T;
Cines DB;
Bdeir, Khalil;
Higazi, Abd Al-Roof;
Kulikovskaya, Irina;
Christofidou-Solomidou, Melpo;
Vinogradov, Sergei A;
Allen, Timothy C;
Idell, Steven;
Linzmeier, Rose;
Ganz, Tomas;
Cines, Douglas B

Publication type:

journal article

Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.

Published in:

2009

By:

Ding BS;
Hong N;
Christofidou-Solomidou M;
Gottstein C;
Albelda SM;
Cines DB;
Fisher AB;
Muzykantov VR;
Ding, Bi-Sen;
Hong, Nankang;
Christofidou-Solomidou, Melpo;
Gottstein, Claudia;
Albelda, Steven M;
Cines, Douglas B;
Fisher, Aron B;
Muzykantov, Vladimir R

Publication type:

journal article

The distinctive structure and composition of arterial and venous thrombi and pulmonary emboli.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59526-x

By:

Chernysh, Irina N.;
Nagaswami, Chandrasekaran;
Kosolapova, Sofia;
Peshkova, Alina D.;
Cuker, Adam;
Cines, Douglas B.;
Cambor, Carolyn L.;
Litvinov, Rustem I.;
Weisel, John W.

Publication type:

Article

Management of antithrombotic therapy in adults with immune thrombocytopenia (ITP): a survey of ITP specialists and general hematologist-oncologists.

Published in:

Journal of Thrombosis & Thrombolysis, 2018, v. 46, n. 1, p. 24, doi. 10.1007/s11239-018-1649-7

By:

Pishko, Allyson M.;
Misgav, Mudi;
Cuker, Adam;
Cines, Douglas B.;
George, James N.;
Vesely, Sara K.;
Terrell, Deirdra R.

Publication type:

Article

Atomic description of the immune complex involved in heparin-induced thrombocytopenia.

Published in:

Nature Communications, 2015, v. 6, n. 9, p. 8277, doi. 10.1038/ncomms9277

By:

Cai, Zheng;
Yarovoi, Serge V.;
Zhu, Zhiqiang;
Rauova, Lubica;
Hayes, Vincent;
Lebedeva, Tatiana;
Liu, Qun;
Poncz, Mortimer;
Arepally, Gowthami;
Cines, Douglas B.;
Greene, Mark I.

Publication type:

Article

Danazol therapy in myelodysplasia.

Published in:

1985

By:

Cines, Douglas B.;
Cassileth, Peter A.;
Kiss, Joseph E.;
Cines, D B;
Cassileth, P A;
Kiss, J E

Publication type:

journal article

ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 1. Structural and functional characterization in vitro.

Published in:

2016

By:

Ostertag, Eric M.;
Kacir, Stephen;
Thiboutot, Michelle;
Gulendran, Gayathri;
Zheng, X. Long;
Cines, Douglas B.;
Siegel, Don L.

Publication type:

journal article

ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model.

Published in:

2016

By:

Ostertag, Eric M.;
Bdeir, Khalil;
Kacir, Stephen;
Thiboutot, Michelle;
Gulendran, Gayathri;
Yunk, Lenka;
Hayes, Vincent M.;
Motto, David G.;
Poncz, Mortimer;
Zheng, X. Long;
Cines, Douglas B.;
Siegel, Don L.

Publication type:

journal article

T2 Magnetic Resonance: A Diagnostic Platform for Studying Integrated Hemostasis in Whole Blood--Proof of Concept.

Published in:

Clinical Chemistry, 2014, v. 60, n. 9, p. 1174, doi. 10.1373/clinchem.2014.223735

By:

Skewis, Lynell R.;
Lebedeva, Tatiana;
Papkov, Vyacheslav;
Thayer, Edward C.;
Massefski, Walter;
Cuker, Adam;
Nagaswami, Chandrasekaran;
Litvinov, Rustem I.;
Kowalska, M. Anna;
Rauova, Lubica;
Poncz, Mortimer;
Weisel, John W.;
Lowery, Thomas J.;
Cines, Douglas B.

Publication type:

Article

Pathogenesis of refractory ITP: Overview.

Published in:

British Journal of Haematology, 2023, v. 203, n. 1, p. 10, doi. 10.1111/bjh.19083

By:

Cines, Douglas B.

Publication type:

Article

Divergent impacts of tocilizumab and colchicine in COVID‐19‐associated coagulopathy: the role of alpha‐defensins.

Published in:

British Journal of Haematology, 2022, v. 196, n. 4, p. 923, doi. 10.1111/bjh.17885

By:

Abdeen, Suhair;
Abu‐Fanne, Rami;
Bdeir, Khalil;
Maraga, Emad;
Higazi, Mohamed;
Cines, Douglas B.;
Heyman, Samuel N.;
Higazi, Abd Al‐Roof

Publication type:

Article

Alpha‐defensins: risk factor for thrombosis in COVID‐19 infection.

Published in:

British Journal of Haematology, 2021, v. 194, n. 1, p. 44, doi. 10.1111/bjh.17503

By:

Abdeen, Suhair;
Bdeir, Khalil;
Abu‐Fanne, Rami;
Maraga, Emad;
Higazi, Mohamed;
Khurram, Nigar;
Feldman, Michael;
Deshpande, Charuhas;
Litzky, Leslie A.;
Heyman, Samuel N.;
Montone, Kathleen T.;
Cines, Douglas B.;
Higazi, Abd Al‐Roof

Publication type:

Article

Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury.

Published in:

FASEB Journal, 2017, v. 31, n. 2, p. 761, doi. 10.1096/fj.201600912R

By:

Carnemolla, Ronald;
Villa, Carlos H.;
Greineder, Colin F.;
Zaitsev, Sergei;
Patel, Kruti R.;
Kowalska, M. Anna;
Atochin, Dmitriy N.;
Cines, Douglas B.;
Siegel, Don L.;
Esmon, Charles T.;
Muzykantov, Vladimir R.

Publication type:

Article

Regulation of neovascularization by human neutrophil peptides (α-defensins): a link between inflammation and angiogenesis.

Published in:

FASEB Journal, 2004, v. 18, n. 11, p. 1306, doi. 10.1096/fj.03-1009fje

By:

Chavakis, Triantafyllos;
Cines, Douglas B.;
Rhee, Joong-Sup;
Liang, Olin D.;
Schubert, Uwe;
Hammes, Hans-Peter;
Higazi, Abd Al-Roof;
Nawroth, Peter P.;
Preissner, Klaus T.;
Bdeir, Khalil

Publication type:

Article

Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders.

Published in:

Journal of Neurochemistry, 2010, v. 113, n. 2, p. 303, doi. 10.1111/j.1471-4159.2010.06613.x

By:

Armstead, William M.;
Ganguly, Kumkum;
Kiessling, J. W.;
Riley, John;
Xiao-Han Chen;
Smith, Douglas H.;
Stein, Sherman C.;
Higazi, Abd A. R.;
Cines, Douglas B.;
Bdeir, Khalil;
Zaitsev, Sergei;
Muzykantov, Vladimir R.

Publication type:

Article

Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation during hypotension after traumatic brain injury through inhibition of ERK and JNK MAPK.

Published in:

Neurological Research, 2012, v. 34, n. 6, p. 530, doi. 10.1179/1743132812Y.0000000039

By:

Armstead, William M;
Riley, John;
Cines, Douglas B;
Higazi, Abd Al-Roof

Publication type:

Article

tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.

Published in:

Neurological Research, 2011, v. 33, n. 7, p. 726, doi. 10.1179/016164110X12807570509853

By:

Armstead, William M;
Willis Kiessling, J;
Riley, John;
Cines, Douglas B;
Higazi, Abd Al-Roof

Publication type:

Article

Heparin-induced thrombocytopenia: An autoimmune disorder regulated through dynamic autoantigen assembly/disassembly.

Published in:

Journal of Clinical Apheresis, 2007, v. 22, n. 1, p. 31, doi. 10.1002/jca.20109

By:

Cines, Douglas B.;
Rauova, Lubica;
Arepally, Gowthami;
Reilly, Michael P.;
McKenzie, Steven E.;
Sachais, Bruce S.;
Poncz, Mortimer

Publication type:

Article

Romiplostim.

Published in:

2008

By:

Cines, Douglas B.;
Yasothan, Uma;
Kirkpatrick, Peter

Publication type:

journal article

Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87667-0

By:

Dong, Yi Na;
Hsu, Fu-Chun;
Koziol-White, Cynthia J.;
Stepanova, Victoria;
Jude, Joseph;
Gritsiuta, Andrei;
Rue, Ryan;
Mott, Rosalind;
Coulter, Douglas A.;
Panettieri, Reynold A.;
Krymskaya, Vera P.;
Takano, Hajime;
Goncharova, Elena A.;
Goncharov, Dmitry A.;
Cines, Douglas B.;
Lynch, David R.

Publication type:

Article

Neutralizing the neurotoxic effects of exogenous and endogenous tPA.

Published in:

Nature Neuroscience, 2006, v. 9, n. 9, p. 1150, doi. 10.1038/nn1757

By:

Armstead, William M.;
Nassar, Taher;
Akkawi, Saed;
Smith, Douglas H.;
Xiao-Han Chen;
Cines, Douglas B.;
Higazi, Abd Al-Roof

Publication type:

Article

Precision targeting of the plasminogen activator inhibitor‐1 mechanism increases efficacy of fibrinolytic therapy in empyema.

Published in:

Physiological Reports, 2021, v. 9, n. 9, p. 1, doi. 10.14814/phy2.14861

By:

Florova, Galina;
Girard, René A.;
Azghani, Ali O.;
Sarva, Krishna;
Buchanan, Ann;
Karandashova, Sophia;
DeVera, Christian J.;
Morris, Danna;
Chamiso, Mignote;
Koenig, Kathleen;
Cines, Douglas B.;
Idell, Steven;
Komissarov, Andrey A.

Publication type:

Article

Human Neutrophil Peptides (HNPs) Inhibit Proteolytic Cleavage of von Willebrand Factor by ADAMTS13: A Potential Link between Inflammation and Thrombotic Thrombocytopenic Purpura.

Published in:

2017

By:

Pillai, Vikram G;
Bao, Jialing;
Zander, Catherine B;
McDaniel, Jenny;
Seeholzer, Steven H;
Bdeir, Khalil;
Cines, Douglas B;
Zhen, X Long

Publication type:

journal article

Rapid Evaluation of Platelet Function With T2 Magnetic Resonance.

Published in:

2016

By:

Cuker, Adam;
Husseinzadeh, Holleh;
Lebedeva, Tatiana;
Marturano, Joseph E.;
Massefski, Walter;
Lowery, Thomas J.;
Lambert, Michele P.;
Abrams, Charles S.;
Weisel, John W.;
Cines, Douglas B.

Publication type:

journal article

Variability in the expression of urokinase receptor (CD87) mutants on cells: relevance to cell adhesion.

Published in:

Cell Biochemistry & Function, 2004, v. 22, n. 4, p. 257, doi. 10.1002/cbf.1098

By:

Kanse, Sandip M.;
Chavakis, Triantafyllos;
Kuo, Alice;
Bdeir, Khalil;
Cines, Douglas B.;
Preissner, Klaus T.

Publication type:

Article

Future research in ITP: an ICIS consensus.

Published in:

2010

By:

Zehnder, James L.;
Semple, John W.;
Imbach, Paul;
Neufeld, Ellis J.;
Buchanan, George R.;
Cines, Douglas B.;
ICIS Study Group on Future Research in ITP

Publication type:

journal article

Red blood cells-coupled tPA prevents impairment of cerebral vasodilatory responses and tissue injury in pediatric cerebral hypoxia/ischemia through inhibition of ERK MAPK activation.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2009, v. 29, n. 8, p. 1463, doi. 10.1038/jcbfm.2009.61

By:

Armstead, William M.;
Ganguly, Kumkum;
Kiessling, John W.;
Smith, Douglas H.;
Higazi, Abd AR.;
Cines, Douglas B.;
Bdeir, Khalil;
Muzykantov, Vladimir R.;
Zaitsev, Sergei;
Xiao-Han Chen

Publication type:

Article

uPA modulates the age-dependent effect of brain injury on cerebral hemodynamics through LRP and ERK MAPK.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2009, v. 29, n. 3, p. 524, doi. 10.1038/jcbfm.2008.142

By:

Armstead, William M.;
Cines, Douglas B.;
Bdeir, Khalil H.;
Bdeir, Yasmina;
Stein, Sherman C.;
Al-Roof Higazi, Abd

Publication type:

Article