Works by Churchman, Michael

Results: 21

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60655-y

By:

Ewing, Ailith;
Meynert, Alison;
Silk, Ryan;
Aitken, Stuart;
Bendixsen, Devin P.;
Churchman, Michael;
Brown, Stuart L.;
Hamdan, Alhafidz;
Mattocks, Joanne;
Grimes, Graeme R.;
Ballinger, Tracy;
Hollis, Robert L.;
Simon Herrington, C.;
Thomson, John P.;
Sherwood, Kitty;
Parry, Thomas;
Esiri-Bloom, Edward;
Bartos, Clare;
Croy, Ian;
Ferguson, Michelle

Publication type:

Article

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.

Published in:

2018

By:

Hollis, Robert L.;
Meynert, Alison M.;
Churchman, Michael;
Rye, Tzyvia;
Mackean, Melanie;
Nussey, Fiona;
Arends, Mark J.;
Sims, Andrew H.;
Semple, Colin A.;
Herrington, C. Simon;
Gourley, Charlie

Publication type:

journal article

Before Chinese and Vietnamese in the Red River Plain: The Han-Tang Period.

Published in:

Chinese Southern Diaspora Studies, 2010, v. 4, p. 25

By:

Churchman, Michael

Publication type:

Article

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.

Published in:

Nature Genetics, 2010, v. 42, n. 11, p. 973, doi. 10.1038/ng.670

By:

Houlston, Richard S.;
Cheadle, Jeremy;
Dobbins, Sara E.;
Tenesa, Albert;
Jones, Angela M.;
Howarth, Kimberley;
Spain, Sarah L.;
Broderick, Peter;
Domingo, Enric;
Farrington, Susan;
Prendergast, James G. D.;
Pittman, Alan M.;
Theodoratou, Evi;
Smith, Christopher G.;
Olver, Bianca;
Walther, Axel;
Barnetson, Rebecca A.;
Churchman, Michael;
Jaeger, Emma E. M.;
Penegar, Steven

Publication type:

Article

The survival benefit associated with complete macroscopic resection in epithelial ovarian cancer is histotype specific.

Published in:

JNCI Cancer Spectrum, 2024, v. 8, n. 4, p. 1, doi. 10.1093/jncics/pkae049

By:

Porter, Joanna M;
McFarlane, Iona;
Bartos, Clare;
Churchman, Michael;
May, James;
Herrington, C Simon;
Connolly, Kathryn C;
Ryan, Neil A J;
Hollis, Robert L

Publication type:

Article

Distinct histopathological features are associated with molecular subtypes and outcome in low grade serous ovarian carcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-34627-5

By:

Hollis, Robert L.;
Thomson, John P.;
van Baal, Juliette;
Ilenkovan, Narthana;
Churchman, Michael;
van de Vijver, Koen;
Dijk, Frederike;
Meynert, Alison M.;
Bartos, Clare;
Rye, Tzyvia;
Croy, Ian;
Diana, Patricia;
van Gent, Mignon;
Creedon, Helen;
Nirsimloo, Rachel;
Lok, Christianne;
Gourley, Charlie;
Herrington, C. Simon

Publication type:

Article

Integrated molecular characterisation of endometrioid ovarian carcinoma identifies opportunities for stratification.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00187-y

By:

Hollis, Robert L.;
Stanley, Barbara;
Thomson, John P.;
Churchman, Michael;
Croy, Ian;
Rye, Tzyvia;
Bartos, Clare;
Nussey, Fiona;
Mackean, Melanie;
Meynert, Alison M.;
Semple, Colin A.;
Gourley, Charlie;
Herrington, C. Simon

Publication type:

Article

Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells.

Published in:

Cancers, 2020, v. 12, n. 6, p. 1503, doi. 10.3390/cancers12061503

By:

Gomez, Miriam K.;
Illuzzi, Giuditta;
Colomer, Carlota;
Churchman, Michael;
Hollis, Robert L.;
O'Connor, Mark J.;
Gourley, Charlie;
Leo, Elisabetta;
Melton, David W.

Publication type:

Article

Intronic sequence variants of the CDKN2A gene in melanoma pedigrees.

Published in:

Genes, Chromosomes & Cancer, 2005, v. 43, n. 2, p. 128, doi. 10.1002/gcc.20177

By:

Mark Harland;
Claire F. Taylor;
Sylvia Bass;
Michael Churchman;
Juliette A. Randerson-Moor;
Elizabeth A. Holland;
Graham J. Mann;
D. Timothy Bishop;
Julia A. Newton Bishop

Publication type:

Article

Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells.

Published in:

European Journal of Gynaecological Oncology, 2022, v. 43, n. 2, p. 183, doi. 10.31083/j.ejgo4302024

By:

Gomez, Miriam K.;
Thomson, John P.;
Grimes, Graeme R.;
Wang, Anderson T.;
Churchman, Michael;
O'Connor, Mark J.;
Gourley, Charlie;
Melton, David W.

Publication type:

Article

Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 2539, doi. 10.2147/OTT.S102569

By:

Hollis, Robert L.;
Churchman, Michael;
Gourley, Charlie

Publication type:

Article

High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum.

Published in:

2019

By:

Hollis, Robert L.;
Churchman, Michael;
Michie, Caroline O.;
Rye, Tzyvia;
Knight, Laura;
McCavigan, Andrena;
Perren, Timothy;
Williams, Alistair R. W.;
McCluggage, W. Glenn;
Kaplan, Richard S.;
Jayson, Gordon C.;
Oza, Amit;
Harkin, D. Paul;
Herrington, C. Simon;
Kennedy, Richard;
Gourley, Charlie

Publication type:

journal article

Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma.

Published in:

British Journal of Cancer, 2024, v. 130, n. 2, p. 327, doi. 10.1038/s41416-023-02508-3

By:

Herrington, C. Simon;
Oswald, Ailsa J.;
Stillie, Lorna J.;
Croy, Ian;
Churchman, Michael;
Hollis, Robert L.

Publication type:

Article

Ovarian carcinosarcoma is a distinct form of ovarian cancer with poorer survival compared to tubo-ovarian high-grade serous carcinoma.

Published in:

2022

By:

Hollis, Robert L.;
Croy, Ian;
Churchman, Michael;
Bartos, Clare;
Rye, Tzyvia;
Gourley, Charlie;
Herrington, C. Simon

Publication type:

journal article

Clinicopathological Determinants of Recurrence Risk and Survival in Mucinous Ovarian Carcinoma.

Published in:

Cancers, 2021, v. 13, n. 22, p. 5839, doi. 10.3390/cancers13225839

By:

Hollis, Robert L.;
Stillie, Lorna J.;
Hopkins, Samantha;
Bartos, Clare;
Churchman, Michael;
Rye, Tzyvia;
Nussey, Fiona;
Fegan, Scott;
Nirsimloo, Rachel;
Inman, Gareth J.;
Herrington, C. Simon;
Gourley, Charlie

Publication type:

Article

Analysis of variants in DNA damage signalling genes in bladder cancer.

Published in:

BMC Medical Genetics, 2008, v. 9, p. 1, doi. 10.1186/1471-2350-9-69

By:

Choudhury, Ananya;
Elliott, Faye;
Iles, Mark M.;
Churchman, Michael;
Bristow, Robert G.;
Bishop, D Timothy;
Kiltie, Anne E.

Publication type:

Article

Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18819-5

By:

Hollis, Robert L.;
Thomson, John P.;
Stanley, Barbara;
Churchman, Michael;
Meynert, Alison M.;
Rye, Tzyvia;
Bartos, Clare;
Iida, Yasushi;
Croy, Ian;
Mackean, Melanie;
Nussey, Fiona;
Okamoto, Aikou;
Semple, Colin A.;
Gourley, Charlie;
Herrington, C. Simon

Publication type:

Article

In vitro functional effects of XPC gene rare variants from bladder cancer patients.

Published in:

Carcinogenesis, 2011, v. 32, n. 4, p. 516, doi. 10.1093/carcin/bgr005

By:

Qiao, Boling;
Ansari, Abdul-Haq;
Scott, Gina B.;
Sak, Sei C.;
Chambers, Philip A.;
Elliott, Faye;
Teo, Mark T.W.;
Bentley, Johanne;
Churchman, Michael;
Hall, Janet;
Taylor, Claire F.;
Bishop, Timothy D.;
Knowles, Margaret A.;
Kiltie, Anne E.

Publication type:

Article

Pharmacogenetics of Smoking Cessation in General Practice: Results From the Patch II and Patch in Practice Trials.

Published in:

Nicotine & Tobacco Research, 2011, v. 13, n. 3, p. 157, doi. 10.1093/ntr/ntq246

By:

David, Sean P.;
Johnstone, Elaine C.;
Churchman, Michael;
Aveyard, Paul;
Murphy, Michael F.G.;
Munafò, Marcus R.

Publication type:

Article

In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours.

Published in:

Journal of Pathology, 2000, v. 192, n. 2, p. 203, doi. 10.1002/1096-9896(2000)9999:9999<::AID-PATH686>3.0.CO;2-J

By:

Rowan, Andrew;
Churchman, Michael;
Jefferey, Rosemary;
Hanby, Andrew;
Poulsom, Richard;
Tomlinson, Ian

Publication type:

Article

The molecular origin and taxonomy of mucinous ovarian carcinoma.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11862-x

By:

Cheasley, Dane;
Wakefield, Matthew J.;
Ryland, Georgina L.;
Allan, Prue E.;
Alsop, Kathryn;
Amarasinghe, Kaushalya C.;
Ananda, Sumitra;
Anglesio, Michael S.;
Au-Yeung, George;
Böhm, Maret;
Bowtell, David D. L.;
Brand, Alison;
Chenevix-Trench, Georgia;
Christie, Michael;
Chiew, Yoke-Eng;
Churchman, Michael;
DeFazio, Anna;
Demeo, Renee;
Dudley, Rhiannon;
Fairweather, Nicole

Publication type:

Article