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Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues.
Published in:
Journal of NeuroVirology, 2006, v. 12, n. 2, p. 146, doi. 10.1080/13550280600748946
By:
- Churchill, Melissa J.;
- Gorry, Paul R.;
- Cowley, Daniel;
- Lal, Luxshimi;
- Sonza, Secondo;
- Purcell, Damian F. J.;
- Thompson, Katherine A.;
- Gabuzda, Dana;
- McArthur, Justin C.;
- Pardo, Carlos A.;
- Wesselingh, Steven L.
Publication type:
Article
HIV transcription persists in the brain of virally suppressed people with HIV.
Published in:
PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012446
By:
- Jamal Eddine, Janna;
- Angelovich, Thomas A.;
- Zhou, Jingling;
- Byrnes, Sarah J.;
- Tumpach, Carolin;
- Saraya, Nadia;
- Chalmers, Emily;
- Shepherd, Rory A.;
- Tan, Abigail;
- Marinis, Stephanie;
- Gorry, Paul R.;
- Estes, Jacob D.;
- Brew, Bruce J.;
- Lewin, Sharon R.;
- Telwatte, Sushama;
- Roche, Michael;
- Churchill, Melissa J.
Publication type:
Article
Ex Vivo Response to Histone Deacetylase (HDAC) Inhibitors of the HIV Long Terminal Repeat (LTR) Derived from HIV-Infected Patients on Antiretroviral Therapy.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113341
By:
- Lu, Hao K.;
- Gray, Lachlan R.;
- Wightman, Fiona;
- Ellenberg, Paula;
- Khoury, Gabriela;
- Cheng, Wan-Jung;
- Mota, Talia M.;
- Wesselingh, Steve;
- Gorry, Paul R.;
- Cameron, Paul U.;
- Churchill, Melissa J.;
- Lewin, Sharon R.
Publication type:
Article
Covariance of Charged Amino Acids at Positions 322 and 440 of HIV-1 Env Contributes to Coreceptor Specificity of Subtype B Viruses, and Can Be Used to Improve the Performance of V3 Sequence-Based Coreceptor Usage Prediction Algorithms.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109771
By:
- Cashin, Kieran;
- Sterjovski, Jasminka;
- Harvey, Katherine L.;
- Ramsland, Paul A.;
- Churchill, Melissa J.;
- Gorry, Paul R.
Publication type:
Article
HIV-1 Entry and Trans-Infection of Astrocytes Involves CD81 Vesicles.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0090620
By:
- Gray, Lachlan R.;
- Turville, Stuart G.;
- HItchen, Tina L.;
- Cheng, Wan-Jung;
- Ellett, Anne M.;
- Salimi, Hamid;
- Roche, Michael J.;
- Wesselingh, Steve L.;
- Gorry, Paul R.;
- Churchill, Melissa J.
Publication type:
Article
The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062196
By:
- Gray, Lachlan R.;
- Tachedjian, Gilda;
- Ellett, Anne M.;
- Roche, Michael J.;
- Cheng, Wan-Jung;
- Guillemin, Gilles J.;
- Brew, Bruce J.;
- Turville, Stuart G.;
- Wesselingh, Steve L.;
- Gorry, Paul R.;
- Churchill, Melissa J.
Publication type:
Article
Increased Sensitivity to Broadly Neutralizing Antibodies of End-Stage Disease R5 HIV-1 Correlates with Evolution in Env Glycosylation and Charge.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020135
By:
- Borggren, Marie;
- Repits, Johanna;
- Sterjovski, Jasminka;
- Uchtenhagen, Hannes;
- Churchill, Melissa J.;
- Karlsson, Anders;
- Albert, Jan;
- Achour, Adnane;
- Gorry, Paul R.;
- Fenyü, Eva Maria;
- Jansson, Marianne
Publication type:
Article
SURVEY AND SUMMARY A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter.
Published in:
Nucleic Acids Research, 2000, v. 28, n. 3, p. 663, doi. 10.1093/nar/28.3.663
By:
- Pereira, Lloyd A.;
- Bentley, Karen;
- Peeters, Anna;
- Churchill, Melissa J;
- Deacon, Nicholas J.
Publication type:
Article
Characterization of Interactions between Transcription Factors and a Regulatory Region Spanning nt –320 to –281 of the HIV-1 LTR in T-Lymphoid and Non-T-Lymphoid Cells.
Published in:
Journal of Biomedical Science, 2002, v. 9, n. 1, p. 68, doi. 10.1159/000048201
By:
- Pereira, Lloyd A.;
- Churchill, Melissa J.;
- Elefanty, Andrew G.;
- Gouskos, Theo;
- Lambert, Paul F.;
- Ramsay, Robert G.;
- Deacon, Nicholas J.
Publication type:
Article
Longitudinal analysis of subtype C envelope tropism for memory CD4+ T cell subsets over the first 3 years of untreated HIV-1 infection.
Published in:
Retrovirology, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12977-020-00532-2
By:
- Gartner, Matthew J.;
- Gorry, Paul R.;
- Tumpach, Carolin;
- Zhou, Jingling;
- Dantanarayana, Ashanti;
- Chang, J. Judy;
- Angelovich, Thomas A.;
- Ellenberg, Paula;
- Laumaea, Annemarie E.;
- Nonyane, Molati;
- Moore, Penny L.;
- Lewin, Sharon R.;
- Churchill, Melissa J.;
- Flynn, Jacqueline K.;
- Roche, Michael
Publication type:
Article
Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 9, p. 1997, doi. 10.3390/v14091997
By:
- Byrnes, Sarah J.;
- Angelovich, Thomas A.;
- Busman-Sahay, Kathleen;
- Cochrane, Catherine R.;
- Roche, Michael;
- Estes, Jacob D.;
- Churchill, Melissa J.
Publication type:
Article
Modular Lentiviral Vectors for Highly Efficient Transgene Expression in Resting Immune Cells.
Published in:
Viruses (1999-4915), 2021, v. 13, n. 6, p. 1170, doi. 10.3390/v13061170
By:
- Fichter, Christina;
- Aggarwal, Anupriya;
- Wong, Andrew Kam Ho;
- McAllery, Samantha;
- Mathivanan, Vennila;
- Hao, Bailey;
- MacRae, Hugh;
- Churchill, Melissa J.;
- Gorry, Paul R.;
- Roche, Michael;
- Gray, Lachlan R.;
- Turville, Stuart
Publication type:
Article
Quantifying Susceptibility of CD4+ Stem Memory T-Cells to Infection by Laboratory Adapted and Clinical HIV-1 Strains.
Published in:
Viruses (1999-4915), 2014, v. 6, n. 2, p. 709, doi. 10.3390/v6020709
By:
- Flynn, Jacqueline K.;
- Paukovics, Geza;
- Cashin, Kieran;
- Borm, Katharina;
- Ellett, Anne;
- Roche, Michael;
- Jakobsen, Martin R.;
- Churchill, Melissa J.;
- Gorry, Paul R.
Publication type:
Article
Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV.
Published in:
Annals of Neurology, 2023, v. 94, n. 4, p. 798, doi. 10.1002/ana.26750
By:
- Angelovich, Thomas A.;
- Cochrane, Catherine R.;
- Zhou, Jingling;
- Tumpach, Carolin;
- Byrnes, Sarah J.;
- Jamal Eddine, Janna;
- Waring, Emily;
- Busman‐Sahay, Kathleen;
- Deleage, Claire;
- Jenkins, Trisha A.;
- Hearps, Anna C.;
- Turville, Stuart;
- Gorry, Paul R.;
- Lewin, Sharon R.;
- Brew, Bruce J.;
- Estes, Jacob D.;
- Roche, Michael;
- Churchill, Melissa J.
Publication type:
Article
Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART.
Published in:
2022
By:
- Cochrane, Catherine R.;
- Angelovich, Thomas A.;
- Byrnes, Sarah J.;
- Waring, Emily;
- Guanizo, Aleks C.;
- Trollope, Gemma S.;
- Zhou, Jingling;
- Vue, Judith;
- Senior, Lachlan;
- Wanicek, Emma;
- Eddine, Janna Jamal;
- Gartner, Matthew J.;
- Jenkins, Trisha A.;
- Gorry, Paul R.;
- Brew, Bruce J.;
- Lewin, Sharon R.;
- Estes, Jacob D.;
- Roche, Michael;
- Churchill, Melissa J.
Publication type:
journal article
Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia.
Published in:
Annals of Neurology, 2009, v. 66, n. 2, p. 253, doi. 10.1002/ana.21697
By:
- Churchill, Melissa J.;
- Wesselingh, Steven L.;
- Cowley, Daniel;
- Pardo, Carlos A.;
- McArthur, Justin C.;
- Brew, Bruce J.;
- Gorry, Paul R.
Publication type:
Article
Astrocyte specific viral strains in HIV dementia.
Published in:
Annals of Neurology, 2004, v. 56, n. 6, p. 873
By:
- Katherine A. Thompson;
- Melissa J. Churchill;
- Paul R. Gorry;
- Jasminka Sterjovski;
- Robert B. Oelrichs;
- Steven L. Wesselingh;
- Catriona A. McLean
Publication type:
Article
Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc.
Published in:
Retrovirology, 2016, v. 13, p. 1, doi. 10.1186/s12977-016-0309-2
By:
- Borm, Katharina;
- Jakobsen, Martin R.;
- Cashin, Kieran;
- Flynn, Jacqueline K.;
- Ellenberg, Paula;
- Ostergaard, Lars;
- Lee, Benhur;
- Churchill, Melissa J.;
- Roche, Michael;
- Gorry, Paul R.
Publication type:
Article
Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4+ T-cell subsets, including stem cell memory T-cells
Published in:
Retrovirology, 2014, v. 11, n. 1, p. 97, doi. 10.1186/s12977-014-0097-5
By:
- Cashin, Kieran;
- Paukovics, Geza;
- Jakobsen, Martin R;
- Østergaard, Lars;
- Churchill, Melissa J;
- Gorry, Paul R;
- Flynn, Jacqueline K
Publication type:
Article
Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection.
Published in:
Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-98
By:
- Cashin, Kieran;
- Jakobsen, Martin R.;
- Sterjovski, Jasminka;
- Roche, Michael;
- Ellett, Anne;
- Flynn, Jacqueline K.;
- Borm, Katharina;
- Gouillou, Maelenn;
- Churchill, Melissa J.;
- Gorry, Paul R.
Publication type:
Article
CoRSeqV3-C: a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm.
Published in:
Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-24
By:
- Cashin, Kieran;
- Gray, Lachlan R.;
- Jakobsen, Martin R.;
- Sterjovski, Jasminka;
- Churchill, Melissa J.;
- Gorry, Paul R.
Publication type:
Article
A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations.
Published in:
Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-43
By:
- Roche, Michael;
- Salimi, Hamid;
- Duncan, Renee;
- Wilkinson, Brendan L.;
- Chikere, Kelechi;
- Moore, Miranda S.;
- Webb, Nicholas E.;
- Zappi, Helena;
- Sterjovski, Jasminka;
- Flynn, Jacqueline K.;
- Ellett, Anne;
- Gray, Lachlan R.;
- Lee, Benhur;
- Jubb, Becky;
- Westby, Mike;
- Ramsland, Paul A.;
- Lewin, Sharon R.;
- Payne, Richard J.;
- Churchill, Melissa J.;
- Gorry, Paul R.
Publication type:
Article
Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues.
Published in:
Retrovirology, 2011, v. 8, n. 1, p. 42, doi. 10.1186/1742-4690-8-42
By:
- Gray, Lachlan;
- Sterjovski, Jasminka;
- Ramsland, Paul A.;
- Churchill, Melissa J.;
- Gorry, Paul R.
Publication type:
Article
Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression.
Published in:
Retrovirology, 2008, v. 5, p. 1, doi. 10.1186/1742-4690-5-28
By:
- Borggren, Marie;
- Repits, Johanna;
- Kuylenstierna, Carlotta;
- Sterjovski, Jasminka;
- Churchill, Melissa J.;
- Purcell, Damian F. J.;
- Karlsson, Anders;
- Albert, Jan;
- Gorry, Paul R.;
- Jansson, Marianne
Publication type:
Article
Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.
Published in:
Retrovirology, 2007, v. 4, p. 89, doi. 10.1186/1742-4690-4-89
By:
- Sterjovski, Jasminka;
- Churchill, Melissa J.;
- Ellett, Anne;
- Gray, Lachlan R.;
- Roche, Michael J.;
- Dunfee, Rebecca L.;
- Purcell, Damian F. J.;
- Saksena, Nitin;
- Bin Wang;
- Sonza, Secondo;
- Wesselingh, Steven L.;
- Karlsson, Ingrid;
- Fenyo, Eva-Maria;
- Gabuzda, Dana;
- Cunningham, Anthony L.;
- Gorry, Paul R.
Publication type:
Article
Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo.
Published in:
Retrovirology, 2007, v. 4, p. 66, doi. 10.1186/1742-4690-4-66
By:
- Gorry, Paul R.;
- McPhee, Dale A.;
- Verity, Erin;
- Dyer, Wayne B.;
- Wesselingh, Steven L.;
- Learmont, Jennifer;
- Sullivan, John S.;
- Roche, Michael;
- Zaunders, John J.;
- Gabuzda1, Dana;
- Crowe, Suzanne M.;
- Mills, John;
- Lewin, Sharon R.;
- Brew, Bruce J.;
- Cunningham, Anthony L.;
- Churchill, Melissa J.
Publication type:
Article
Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques.
Published in:
PLoS Pathogens, 2023, v. 18, n. 3, p. 1, doi. 10.1371/journal.ppat.1011290
By:
- Byrnes, Sarah J.;
- Busman-Sahay, Kathleen;
- Angelovich, Thomas A.;
- Younger, Skyler;
- Taylor-Brill, Sol;
- Nekorchuk, Michael;
- Bondoc, Stephen;
- Dannay, Rachel;
- Terry, Margaret;
- Cochrane, Catherine R.;
- Jenkins, Trisha A.;
- Roche, Michael;
- Deleage, Claire;
- Bosinger, Steven E.;
- Paiardini, Mirko;
- Brew, Bruce J.;
- Estes, Jacob D.;
- Churchill, Melissa J.
Publication type:
Article

Found: 27

Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues.

HIV transcription persists in the brain of virally suppressed people with HIV.

Ex Vivo Response to Histone Deacetylase (HDAC) Inhibitors of the HIV Long Terminal Repeat (LTR) Derived from HIV-Infected Patients on Antiretroviral Therapy.

Covariance of Charged Amino Acids at Positions 322 and 440 of HIV-1 Env Contributes to Coreceptor Specificity of Subtype B Viruses, and Can Be Used to Improve the Performance of V3 Sequence-Based Coreceptor Usage Prediction Algorithms.

HIV-1 Entry and <i>Trans</i>-Infection of Astrocytes Involves CD81 Vesicles.

The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes.

Increased Sensitivity to Broadly Neutralizing Antibodies of End-Stage Disease R5 HIV-1 Correlates with Evolution in Env Glycosylation and Charge.

SURVEY AND SUMMARY A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter.

Characterization of Interactions between Transcription Factors and a Regulatory Region Spanning nt –320 to –281 of the HIV-1 LTR in T-Lymphoid and Non-T-Lymphoid Cells.

Longitudinal analysis of subtype C envelope tropism for memory CD4+ T cell subsets over the first 3 years of untreated HIV-1 infection.

Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders.

Modular Lentiviral Vectors for Highly Efficient Transgene Expression in Resting Immune Cells.

Quantifying Susceptibility of CD4<sup>+</sup> Stem Memory T-Cells to Infection by Laboratory Adapted and Clinical HIV-1 Strains.

Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV.

Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART.

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia.

Astrocyte specific viral strains in HIV dementia.

Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc.

Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4<sup>+</sup> T-cell subsets, including stem cell memory T-cells

Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection.

CoRSeqV3-C: a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm.

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations.

Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues.

Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression.

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo.

Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques.