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Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 10, p. 1, doi. 10.15252/emmm.202217094
By:
- Brown, Matthew;
- Leon, Alicia;
- Kedzierska, Katarzyna;
- Moore, Charlotte;
- Belnoue‐Davis, Hayley L;
- Flach, Susanne;
- Lydon, John P;
- DeMayo, Francesco J;
- Lewis, Annabelle;
- Bosse, Tjalling;
- Tomlinson, Ian;
- Church, David N
Publication type:
Article
Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape.
Published in:
Journal of Pathology, 2022, v. 257, n. 3, p. 340, doi. 10.1002/path.5894
By:
- Glaire, Mark A;
- Ryan, Neil AJ;
- Ijsselsteijn, Marieke E;
- Kedzierska, Katarzyna;
- Obolenski, Sofia;
- Ali, Reem;
- Crosbie, Emma J;
- Bosse, Tjalling;
- de Miranda, Noel FCC;
- Church, David N
Publication type:
Article
Clinicopathological and molecular characterisation of 'multiple‐classifier' endometrial carcinomas.
Published in:
Journal of Pathology, 2020, v. 250, n. 3, p. 312, doi. 10.1002/path.5373
By:
- León‐Castillo, Alicia;
- Gilvazquez, Ester;
- Nout, Remi;
- Smit, Vincent THBM;
- McAlpine, Jessica N;
- McConechy, Melissa;
- Kommoss, Stefan;
- Brucker, Sara Y;
- Carlson, Joseph W;
- Epstein, Elisabeth;
- Rau, Tilman T;
- Soslow, Robert A;
- Ganesan, Raji;
- Matias‐Guiu, Xavier;
- Oliva, Esther;
- Harrison, Beth T;
- Church, David N;
- Gilks, C Blake;
- Bosse, Tjalling
Publication type:
Article
Interpretation of somatic POLE mutations in endometrial carcinoma.
Published in:
Journal of Pathology, 2020, v. 250, n. 3, p. 323, doi. 10.1002/path.5372
By:
- León‐Castillo, Alicia;
- Britton, Heidi;
- McConechy, Melissa K;
- McAlpine, Jessica N;
- Nout, Remi;
- Kommoss, Stefan;
- Brucker, Sara Y;
- Carlson, Joseph W;
- Epstein, Elisabeth;
- Rau, Tilman T;
- Bosse, Tjalling;
- Church, David N;
- Gilks, C Blake
Publication type:
Article
Cancer predisposition syndromes: lessons for truly precision medicine.
Published in:
Journal of Pathology, 2017, v. 241, n. 2, p. 226, doi. 10.1002/path.4842
By:
- Glaire, Mark A;
- Brown, Matthew;
- Church, David N;
- Tomlinson, Ian
Publication type:
Article
Vaccination of chemotherapy patients--effect of guideline implementation.
Published in:
2016
By:
- Toleman, Michelle;
- Herbert, Katharine;
- McCarthy, Noel;
- Church, David;
- Toleman, Michelle S;
- Church, David N
Publication type:
journal article
Tertiary lymphoid structures critical for prognosis in endometrial cancer patients.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29040-x
By:
- Horeweg, Nanda;
- Workel, Hagma H.;
- Loiero, Dominik;
- Church, David N.;
- Vermij, Lisa;
- Léon-Castillo, Alicia;
- Krog, Ricki T.;
- de Boer, Stephanie M.;
- Nout, Remi A.;
- Powell, Melanie E.;
- Mileshkin, Linda R.;
- MacKay, Helen;
- Leary, Alexandra;
- Singh, Naveena;
- Jürgenliemk-Schulz, Ina M.;
- Smit, Vincent T. H. B. M.;
- Creutzberg, Carien L.;
- Koelzer, Viktor H.;
- Nijman, Hans W.;
- Bosse, Tjalling
Publication type:
Article
A Review of Trastuzumab-Based Therapy in Patients with HER2-positive Metastatic Breast Cancer.
Published in:
Clinical Medicine: Therapeutics, 2009, n. 1, p. 557, doi. 10.4137/CMT.S35
By:
- Church, David N.;
- Price, Chris G. A.
Publication type:
Article
Non-Canonical Activin A Signaling Stimulates Context-Dependent and Cellular-Specific Outcomes in CRC to Promote Tumor Cell Migration and Immune Tolerance.
Published in:
Cancers, 2023, v. 15, n. 11, p. 3003, doi. 10.3390/cancers15113003
By:
- Wiley, Mark B.;
- Bauer, Jessica;
- Mehrotra, Kunaal;
- Zessner-Spitzenberg, Jasmin;
- Kolics, Zoe;
- Cheng, Wenxuan;
- Castellanos, Karla;
- Nash, Michael G.;
- Gui, Xianyong;
- Kone, Lyonell;
- Maker, Ajay V.;
- Qiao, Guilin;
- Reddi, Deepti;
- Church, David N.;
- Kerr, Rachel S.;
- Kerr, David J.;
- Grippo, Paul J.;
- Jung, Barbara
Publication type:
Article
Histological and Somatic Mutational Profiles of Mismatch Repair Deficient Endometrial Tumours of Different Aetiologies.
Published in:
Cancers, 2021, v. 13, n. 18, p. 4538, doi. 10.3390/cancers13184538
By:
- Ryan, Neil A. J.;
- Walker, Thomas D. J.;
- Bolton, James;
- ter Haar, Natalja;
- Van Wezel, Tom;
- Glaire, Mark A.;
- Church, David N.;
- Evans, D. Gareth;
- Bosse, Tjalling;
- Crosbie, Emma J.
Publication type:
Article
The Influence of Activin on the Tumor Microenvironment in Colon Cancer Metastasis.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2434
By:
- Wiley, Mark B.;
- Bauer, Jessica;
- Mehrotra, Kunaal;
- Zessner‐Spitzenberg, Jasmin;
- Kone, Lyonell;
- Quiao, Guilin;
- Castellanos, Karla;
- Church, David N.;
- Kerr, Rachel S.;
- Kerr, David J.;
- Grippo, Paul;
- Maker, Ajay;
- Jung, Barbara
Publication type:
Article
Correction: Tumour-infiltrating CD8<sup>+</sup> lymphocytes and colorectal cancer recurrence by tumour and nodal stage.
Published in:
2019
By:
- Glaire, Mark A.;
- Domingo, Enric;
- Sveen, Anita;
- Bruun, Jarle;
- Nesbakken, Arild;
- Nicholson, George;
- Novelli, Marco;
- Lawson, Kay;
- Oukrif, Dahmane;
- Kildal, Wanja;
- Danielsen, Havard E.;
- Kerr, Rachel;
- Kerr, David;
- Tomlinson, Ian;
- Lothe, Ragnhild A.;
- Church, David N.
Publication type:
corrected article
Tumour-infiltrating CD8<sup>+</sup> lymphocytes and colorectal cancer recurrence by tumour and nodal stage.
Published in:
2019
By:
- Glaire, Mark A.;
- Domingo, Enric;
- Sveen, Anita;
- Bruun, Jarle;
- Nesbakken, Arild;
- Nicholson, George;
- Novelli, Marco;
- Lawson, Kay;
- Oukrif, Dahmane;
- Kildal, Wanja;
- Danielsen, Havard E.;
- Kerr, Rachel;
- Kerr, David;
- Tomlinson, Ian;
- Lothe, Ragnhild A.;
- Church, David N.
Publication type:
journal article
DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer.
Published in:
Human Molecular Genetics, 2013, v. 22, n. 14, p. 2820, doi. 10.1093/hmg/ddt131
By:
- Church, David N.;
- Briggs, Sarah E.W.;
- Palles, Claire;
- Domingo, Enric;
- Kearsey, Stephen J.;
- Grimes, Jonathon M.;
- Gorman, Maggie;
- Martin, Lynn;
- Howarth, Kimberley M.;
- Hodgson, Shirley V.;
- Kaur, Kulvinder;
- Taylor, Jenny;
- Tomlinson, Ian P.M.
Publication type:
Article
Promises and challenges of adoptive T-cell therapies for solid tumours.
Published in:
2021
By:
- Morotti, Matteo;
- Albukhari, Ashwag;
- Alsaadi, Abdulkhaliq;
- Artibani, Mara;
- Brenton, James D.;
- Curbishley, Stuart M.;
- Dong, Tao;
- Dustin, Michael L.;
- Hu, Zhiyuan;
- McGranahan, Nicholas;
- Miller, Martin L.;
- Santana-Gonzalez, Laura;
- Seymour, Leonard W.;
- Shi, Tingyan;
- Van Loo, Peter;
- Yau, Christopher;
- White, Helen;
- Wietek, Nina;
- Church, David N.;
- Wedge, David C.
Publication type:
journal article
Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer.
Published in:
Journal of Pathology: Clinical Research, 2020, v. 6, n. 4, p. 283, doi. 10.1002/cjp2.171
By:
- Roseweir, Antonia K;
- Park, James H;
- Hoorn, Sanne ten;
- Powell, Arfon GMT;
- Aherne, Susan;
- Roxburgh, Campbell SD;
- McMillan, Donald C;
- Horgan, Paul G;
- Ryan, Elizabeth;
- Sheahan, Kieran;
- Vermeulen, Louis;
- Paul, James;
- Harkin, Andrea;
- Graham, Janet;
- Sansom, Owen;
- Church, David N;
- Tomlinson, Ian;
- Saunders, Mark;
- Iveson, Tim J;
- Edwards, Joanne
Publication type:
Article
Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta‐analysis.
Published in:
Cancer (0008543X), 2021, v. 127, n. 14, p. 2409, doi. 10.1002/cncr.33516
By:
- McAlpine, Jessica N.;
- Chiu, Derek S.;
- Nout, Remi A.;
- Church, David N.;
- Schmidt, Pascal;
- Lam, Stephanie;
- Leung, Samuel;
- Bellone, Stefania;
- Wong, Adele;
- Brucker, Sara Y.;
- Lee, Cheng Han;
- Clarke, Blaise A.;
- Huntsman, David G.;
- Bernardini, Marcus Q.;
- Ngeow, Joanne;
- Santin, Alessandro D.;
- Goodfellow, Paul;
- Levine, Douglas A.;
- Köbel, Martin;
- Kommoss, Stefan
Publication type:
Article
Prognostic significance of POLE proofreading mutations in endometrial cancer.
Published in:
2015
By:
- Church, David N;
- Stelloo, Ellen;
- Nout, Remi A;
- Valtcheva, Nadejda;
- Depreeuw, Jeroen;
- Ter Haar, Natalja;
- Noske, Aurelia;
- Amant, Frederic;
- Tomlinson, Ian P M;
- Wild, Peter J;
- Lambrechts, Diether;
- Jürgenliemk-Schulz, Ina M;
- Jobsen, Jan J;
- Smit, Vincent T H B M;
- Creutzberg, Carien L;
- Bosse, Tjalling
Publication type:
journal article
Prognostic Significance of POLE Proofreading Mutations in Endometrial Cancer.
Published in:
JNCI: Journal of the National Cancer Institute, 2014, v. 107, n. 1, p. 1, doi. 10.1093/jnci/dju402
By:
- Church, David N.;
- Stelloo, Ellen;
- Nout, Remi A.;
- Valtcheva, Nadejda;
- Depreeuw, Jeroen;
- ter Haar, Natalja;
- Noske, Aurelia;
- Amant, Frederic;
- Tomlinson, Ian P. M.;
- Wild, Peter J.;
- Lambrechts, Diether;
- Jürgenliemk-Schulz, Ina M.;
- Jobsen, Jan J.;
- Smit, Vincent T. H. B. M.;
- Creutzberg, Carien L.;
- Bosse, Tjalling
Publication type:
Article

Found: 19