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Metallothionein-IIA Promotes Initial Neurite Elongation and Postinjury Reactive Neurite Growth and Facilitates Healing after Focal Cortical Brain Injury.
- Published in:
- Journal of Neuroscience, 2003, v. 23, n. 8, p. 3336, doi. 10.1523/JNEUROSCI.23-08-03336.2003
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- Publication type:
- Article
Effects of mutations in the novel FTD‐ALS gene, CYLD, on SFPQ protein: Developing topics.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047382
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- Publication type:
- Article
Effects of the novel FTD‐ALS gene CYLD on cell death mechanisms: Genetics/atypical and other dementias.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045017
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- Publication type:
- Article
Inter-Regional Proteomic Profiling of the Human Brain Using an Optimized Protein Extraction Method from Formalin-Fixed Tissue to Identify Signaling Pathways.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4283, doi. 10.3390/ijms24054283
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- Article
Extracellular Interactions of Alpha-Synuclein in Multiple System Atrophy.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 4129, doi. 10.3390/ijms19124129
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- Article
Potential Modes of Intercellular α-Synuclein Transmission.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 2, p. 469, doi. 10.3390/ijms18020469
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- Publication type:
- Article
Dexamethasone Inhibits Copper-Induced Alpha-Synuclein Aggregation by a Metallothionein-Dependent Mechanism.
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- Neurotoxicity Research, 2018, v. 33, n. 2, p. 229, doi. 10.1007/s12640-017-9825-7
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- Publication type:
- Article
Ultrastructural Mapping of the Zebrafish Gastrointestinal System as a Basis for Experimental Drug Studies.
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- BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/8758460
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- Publication type:
- Article
Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes.
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- Life (2075-1729), 2020, v. 10, n. 9, p. 183, doi. 10.3390/life10090183
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- Publication type:
- Article
Microglia morphophysiological diversity and its implications for the CNS.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.997786
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- Publication type:
- Article
Editorial: The molecular pathology of cognitive decline: focus on metals.
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- Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00116
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- Publication type:
- Article
Improving the Delivery of SOD1 Antisense Oligonucleotides to Motor Neurons Using Calcium Phosphate-Lipid Nanoparticles.
- Published in:
- Frontiers in Neuroscience, 2017, p. 1, doi. 10.3389/fnins.2017.00476
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- Publication type:
- Article
Metallothionein-IIA blocks copper mediated Aβ<sup>1-40</sup> neurotoxicity
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- 2009
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- Publication type:
- Abstract
Metallothionein (MT) -I and MT-II Expression Are Induced and Cause Zinc Sequestration in the Liver after Brain Injury.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031185
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- Publication type:
- Article
Tg2576 Cortical Neurons That Express Human Ab Are Susceptible to Extracellular Aβ-Induced, K<sup>+</sup> Efflux Dependent Neurodegeneration.
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- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019026
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- Publication type:
- Article
The Native Copper- and Zinc- Binding Protein Metallothionein Blocks Copper-Mediated Aβ Aggregation and Toxicity in Rat Cortical Neurons.
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- PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012030
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- Publication type:
- Article
Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT)-I/II null mutant mice.
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- 2011
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- Publication type:
- journal article
TDP-43 pathology and functional deficits in wild-type and ALS/FTD mutant cyclin F mouse models.
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- Neuropathology & Applied Neurobiology, 2023, v. 49, n. 2, p. 1, doi. 10.1111/nan.12902
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- Publication type:
- Article
TDP‐43 pathology and functional deficits in wild‐type and ALS/FTD mutant cyclin F mouse models.
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- Neuropathology & Applied Neurobiology, 2023, v. 49, n. 1, p. 1, doi. 10.1111/nan.12902
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- Publication type:
- Article
A Robust Intrinsically Green Fluorescent Poly(Amidoamine) Dendrimer for Imaging and Traceable Central Nervous System Delivery in Zebrafish.
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- Small, 2020, v. 16, n. 39, p. 1, doi. 10.1002/smll.202003654
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- Publication type:
- Article
Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00437
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- Publication type:
- Article
The established and emerging roles of astrocytes and microglia in amyotrophic lateral sclerosis and frontotemporal dementia.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00414
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- Publication type:
- Article
Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies.
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- Frontiers in Neuroscience, 2017, v. 11, p. 1, doi. 10.3389/fnins.2017.00114
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- Publication type:
- Article
Transcriptional insights on the regenerative mechanics of axotomized neurons in vitro.
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- Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 4, p. 789, doi. 10.1111/j.1582-4934.2011.01361.x
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- Publication type:
- Article
Isotope metallomics approaches for medical research.
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- Cellular & Molecular Life Sciences, 2020, v. 77, n. 17, p. 3293, doi. 10.1007/s00018-020-03484-0
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- Publication type:
- Article
Aurora kinase B regulates axonal outgrowth and regeneration in the spinal motor neurons of developing zebrafish.
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- Cellular & Molecular Life Sciences, 2018, v. 75, n. 23, p. 4269, doi. 10.1007/s00018-018-2780-5
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- Publication type:
- Article
Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain.
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- FEBS Journal, 2010, v. 277, n. 14, p. 2931, doi. 10.1111/j.1742-4658.2010.07718.x
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- Publication type:
- Article
Striated muscle activator of Rho signalling (STARS) overexpression in the mdx mouse enhances muscle functional capacity and regulates the actin cytoskeleton and oxidative phosphorylation pathways.
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- Experimental Physiology, 2021, v. 106, n. 7, p. 1597, doi. 10.1113/EP089253
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- Publication type:
- Article
ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis.
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- Human Molecular Genetics, 2023, v. 32, n. 14, p. 2386, doi. 10.1093/hmg/ddad063
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- Publication type:
- Article
Riluzole does not ameliorate disease caused by cytoplasmic TDP‐43 in a mouse model of amyotrophic lateral sclerosis.
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- European Journal of Neuroscience, 2021, v. 54, n. 6, p. 6237, doi. 10.1111/ejn.15422
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- Publication type:
- Article
The influence of metallothionein treatment and treadmill running exercise on disease onset and survival in SOD1<sup>G93A</sup> amyotrophic lateral sclerosis mice.
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- European Journal of Neuroscience, 2020, v. 52, n. 4, p. 3223, doi. 10.1111/ejn.14682
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- Publication type:
- Article
Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-β (1–42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators.
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- Journal of Neurochemistry, 2009, v. 110, n. 6, p. 1784, doi. 10.1111/j.1471-4159.2009.06269.x
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- Publication type:
- Article
The impact of metallothionein-II on microglial response to tumor necrosis factor-alpha (TNFα) and downstream effects on neuronal regeneration.
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- 2018
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- Publication type:
- journal article
Metallothionein-IIA promotes neurite growth via the megalin receptor.
- Published in:
- Experimental Brain Research, 2007, v. 183, n. 2, p. 171, doi. 10.1007/s00221-007-1032-y
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- Publication type:
- Article
ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 11, p. 971, doi. 10.1093/hmg/ddab073
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- Publication type:
- Article
Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 4, p. 698, doi. 10.1093/hmg/ddy362
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- Publication type:
- Article
Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype.
- Published in:
- Human Molecular Genetics, 2017, v. 26, n. 14, p. 2616, doi. 10.1093/hmg/ddx136
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- Publication type:
- Article
Chemical reprogramming enhances homology-directed genome editing in zebrafish embryos.
- Published in:
- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0444-0
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- Publication type:
- Article
Switching on Endogenous Metal Binding Proteins in Parkinson's Disease.
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- Cells (2073-4409), 2019, v. 8, n. 2, p. 179, doi. 10.3390/cells8020179
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- Publication type:
- Article
RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 9, p. 5301, doi. 10.1093/nar/gkae112
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- Publication type:
- Article
Prolonged Aβ treatment leads to impairment in the ability of primary cortical neurons to maintain K<sup>+</sup> and Ca<sup>2+</sup> homeostasis.
- Published in:
- Molecular Neurodegeneration, 2010, v. 5, p. 30, doi. 10.1186/1750-1326-5-30
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- Publication type:
- Article
Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase.
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- 2014
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- Publication type:
- journal article
Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury.
- Published in:
- Journal of Neurochemistry, 2004, v. 88, n. 2, p. 454, doi. 10.1046/j.1471-4159.2003.02193.x
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- Publication type:
- Article
The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis.
- Published in:
- Molecular Neurobiology, 2023, v. 60, n. 9, p. 5034, doi. 10.1007/s12035-023-03355-2
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- Publication type:
- Article
In vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS).
- Published in:
- Molecular Neurobiology, 2021, v. 58, n. 5, p. 2061, doi. 10.1007/s12035-020-02238-0
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- Publication type:
- Article
Single siRNA Nanocapsules for Effective siRNA Brain Delivery and Glioblastoma Treatment.
- Published in:
- Advanced Materials, 2023, v. 35, n. 16, p. 1, doi. 10.1002/adma.202300777
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- Publication type:
- Article
Single siRNA Nanocapsules for Effective siRNA Brain Delivery and Glioblastoma Treatment.
- Published in:
- Advanced Materials, 2020, v. 32, n. 24, p. 1, doi. 10.1002/adma.202000416
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- Publication type:
- Article
ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-46802-9
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- Publication type:
- Article
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
- Published in:
- Molecular Brain, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13041-021-00839-x
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- Publication type:
- Article