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Pan-class I PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 3, p. 1, doi. 10.1038/s41419-018-0413-4
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- Article
Dynamin-mediated lipid acquisition is essential for C hlamydia trachomatis development.
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- Molecular Microbiology, 2014, v. 94, n. 1, p. 186, doi. 10.1111/mmi.12751
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- Article
Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection.
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- Nature Protocols, 2022, v. 17, n. 7, p. 1658, doi. 10.1038/s41596-022-00695-6
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- Article
Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28569-1
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- Article
Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47173-z
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- Article
Single object profiles regression analysis (SOPRA): a novel method for analyzing high-content cell-based screens.
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- BMC Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12859-022-04981-8
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- Article
Organoids of the female reproductive tract.
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- Journal of Molecular Medicine, 2021, v. 99, n. 4, p. 531, doi. 10.1007/s00109-020-02028-0
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- Article
Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
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- Journal of Molecular Medicine, 2015, v. 93, n. 5, p. 559, doi. 10.1007/s00109-014-1242-2
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- Article
p14<sup>ARF</sup> induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.
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- International Journal of Cancer, 2013, v. 133, n. 11, p. 2551, doi. 10.1002/ijc.28279
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- Article
Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
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- International Journal of Cancer, 2013, v. 133, n. 8, p. 1813, doi. 10.1002/ijc.28206
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- Article