Works by Chuang-Stein, Christy

Results: 70

Multiple comparisons procedures for comparing several treatments with a control based on binary data.

Published in:

1995

By:

Chuang-Stein, Christy;
Tong, Donald M.;
Chuang-Stein, C;
Tong, D M

Publication type:

journal article

Organization and analysis of safety data using a multivariate approach.

Published in:

Statistics in Medicine, 1992, v. 11, n. 8, p. 1075, doi. 10.1002/sim.4780110809

By:

Chuang-Stein, Christy;
Mohberg, Noel R.;
Musselman, David M.

Publication type:

Article

Three measures for simultaneously evaluating benefits and risks using categorical data from clinical trials.

Published in:

Statistics in Medicine, 1991, v. 10, n. 9, p. 1349, doi. 10.1002/sim.4780100904

By:

Chuang-Stein, Christy;
Mohberg, Noel R.;
Sinkula, Michaline S.

Publication type:

Article

A note on the analysis of titration studies.

Published in:

Statistics in Medicine, 1991, v. 10, n. 3, p. 323, doi. 10.1002/sim.4780100304

By:

Chuang-Stein, Christy;
Shih, Weichung Joseph

Publication type:

Article

Statistics in the Pharmaceutical Industry, 2nd Ed. (Book).

Published in:

1995

By:

Chuang-Stein, Christy

Publication type:

Book Review

The Acute Stroke Therapy by Inhibition of Neutrophils study – Key features and impact.

Published in:

Pharmaceutical Statistics, 2022, v. 21, n. 4, p. 720, doi. 10.1002/pst.2218

By:

Kirby, Simon;
Chuang‐Stein, Christy

Publication type:

Article

Lessons from meta‐analyses of randomized clinical trials for analysis of distributed networks of observational databases.

Published in:

Pharmaceutical Statistics, 2019, v. 18, n. 1, p. 65, doi. 10.1002/pst.1908

By:

Bate, Andrew;
Chuang‐Stein, Christy;
Roddam, Andrew;
Jones, Byron

Publication type:

Article

A comparison of five approaches to decision-making for a first clinical trial of efficacy.

Published in:

Pharmaceutical Statistics, 2017, v. 16, n. 1, p. 37, doi. 10.1002/pst.1775

By:

Kirby, Simon;
Chuang‐Stein, Christy

Publication type:

Article

The shrinking or disappearing observed treatment effect.

Published in:

Pharmaceutical Statistics, 2014, v. 13, n. 5, p. 277, doi. 10.1002/pst.1633

By:

Chuang‐Stein, Christy;
Kirby, Simon

Publication type:

Article

Subgroup analyses in cost-effectiveness analyses to support health technology assessments.

Published in:

Pharmaceutical Statistics, 2014, v. 13, n. 4, p. 265, doi. 10.1002/pst.1626

By:

Fletcher, Christine;
Chuang‐Stein, Christy;
Paget, Marie‐Ange;
Reid, Carol;
Hawkins, Neil

Publication type:

Article

Strong control over multiple endpoints: are we adding value to the assessment of medicines?

Published in:

Pharmaceutical Statistics, 2013, v. 12, n. 4, p. 189, doi. 10.1002/pst.1574

By:

Stone, Andrew;
Chuang‐Stein, Christy

Publication type:

Article

Subgroup analyses of clinical effectiveness to support health technology assessments.

Published in:

Pharmaceutical Statistics, 2011, v. 10, n. 6, p. 532, doi. 10.1002/pst.531

By:

Paget, Marie-Ange;
Chuang-Stein, Christy;
Fletcher, Christine;
Reid, Carol

Publication type:

Article

The role of the minimum clinically important difference and its impact on designing a trial.

Published in:

Pharmaceutical Statistics, 2011, v. 10, n. 3, p. 250, doi. 10.1002/pst.459

By:

Chuang-Stein, Christy;
Kirby, Simon;
Hirsch, Ian;
Atkinson, Gary

Publication type:

Article

Reporting cumulative proportion of subjects with an adverse event based on data from multiple studies.

Published in:

Pharmaceutical Statistics, 2011, v. 10, n. 1, p. 3, doi. 10.1002/pst.397

By:

Chuang-Stein, Christy;
Beltangady, Mohan

Publication type:

Article

What should be the role of homogeneity testing in adaptive trials?

Published in:

Pharmaceutical Statistics, 2009, v. 8, n. 1, p. 1, doi. 10.1002/pst.342

By:

Gallo, Paul;
Chuang-Stein, Christy

Publication type:

Article

A case study comparing a randomized withdrawal trial and a double-blind long-term trial for assessing the long-term efficacy of an antidepressant.

Published in:

Pharmaceutical Statistics, 2007, v. 6, n. 1, p. 9, doi. 10.1002/pst.234

By:

Mallinckrodt, Craig;
Chuang-Stein, Christy;
McSorley, Paul;
Schwartz, Jeffrey;
Archibald, Donald G.;
Perahia, David G.;
Detke, Michael J.;
Alphs, Larry

Publication type:

Article

Sample size and the probability of a successful trial.

Published in:

Pharmaceutical Statistics, 2006, v. 5, n. 4, p. 305, doi. 10.1002/pst.232

By:

Chuang-Stein, Christy

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2005, v. 4, n. 4, p. 231, doi. 10.1002/pst.196

By:

Chuang-Stein, Christy;
Furlong, Larry;
Julious, Steven

Publication type:

Article

Four case studies to highlight some opportunities and challenges in developing anti-bacterial and anti-fungal agents.

Published in:

Pharmaceutical Statistics, 2005, v. 4, n. 4, p. 253, doi. 10.1002/pst.184

By:

Chuang-Stein, Christy;
Heft, Samuel;
Koury, Kenneth

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2005, v. 4, n. 3, p. 153, doi. 10.1002/pst.187

By:

Chuang-Stein, Christy;
Furlong, Larry;
Julious, Steven A.

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2005, v. 4, n. 2, p. 85, doi. 10.1002/pst.171

By:

Chuang-Stein, Christy;
Furlong, Larry;
Julious, Steven A.

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2005, v. 4, n. 1, p. 1, doi. 10.1002/pst.163

By:

Chuang-Stein, Christy;
Furlong, Larry;
Julious, Steven

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2004, v. 3, n. 4, p. 235, doi. 10.1002/pst.150

By:

Chuang-Stein, Christy;
Jones, Byron;
Furlong, Larry

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2004, v. 3, n. 3, p. 155, doi. 10.1002/pst.134

By:

Jones, Byron;
Chuang-Stein, Christy;
Furlong, Larry

Publication type:

Article

Seize the opportunities.

Published in:

Pharmaceutical Statistics, 2004, v. 3, n. 3, p. 157, doi. 10.1002/pst.133

By:

Chuang-Stein, Christy

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2004, v. 3, n. 2, p. 75, doi. 10.1002/pst.122

By:

Chuang-Stein, Christy;
Jones, Byron;
Furlong, Larry

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2004, v. 3, n. 1, p. 1, doi. 10.1002/pst.102

By:

Chuang-Stein, Christy;
Jones, Byron;
Furlong, Larry

Publication type:

Article

Type I error and power in trials with one interim futility analysis.

Published in:

Pharmaceutical Statistics, 2004, v. 3, n. 1, p. 51, doi. 10.1002/pst.93

By:

Chang, William H.;
Chuang-Stein, Christy

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2003, v. 2, n. 4, p. 237, doi. 10.1002/pst.94

By:

Jones, Byron;
Chuang-Stein, Christy;
Furlong, Larry

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2003, v. 2, n. 3, p. 159, doi. 10.1002/pst.79

By:

Chuang-Stein, Christy;
Furlong, Larry;
Jones, Byron

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2003, v. 2, n. 1, p. 1, doi. 10.1002/pst.46

By:

Chuang-Stein, Christy;
Jones, Byron;
Lendrem, Dennis

Publication type:

Article

Editorial.

Published in:

Pharmaceutical Statistics, 2002, v. 1, n. 1, p. 3, doi. 10.1002/pst.1

By:

Chuang-Stein, Christy;
Jones, Byron;
Lendrem, Dennis

Publication type:

Article

Two approaches for the analysis of a titration study with a placebo control.

Published in:

Communications in Statistics: Theory & Methods, 1988, v. 17, n. 3, p. 821, doi. 10.1080/03610928808829657

By:

Christy, Chuang-Stein

Publication type:

Article

Presenting Risks and Benefits: Helping the Data Monitoring Committee Do Its Job.

Published in:

2020

By:

Evans, Scott R.;
Bigelow, Robert;
Chuang-Stein, Christy;
Ellenberg, Susan S.;
Gallo, Paul;
He, Weili;
Jiang, Qi;
Rockhold, Frank

Publication type:

journal article

Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR).

Published in:

Clinical Infectious Diseases, 2015, v. 61, n. 5, p. 800, doi. 10.1093/cid/civ495

By:

Evans, Scott R.;
Rubin, Daniel;
Follmann, Dean;
Pennello, Gene;
Huskins, W. Charles;
Powers, John H.;
Schoenfeld, David;
Chuang-Stein, Christy;
Cosgrove, Sara E.;
Fowler Jr, Vance G.;
Lautenbach, Ebbing;
Chambers, Henry F.

Publication type:

Article

Changes are still needed on multiple co-primary endpoints.

Published in:

2017

By:

Chuang-Stein, Christy;
Li, Jianjun (David)

Publication type:

journal article

An evaluation of therapeutic synergism using linear logit models.

Published in:

Journal of Applied Statistics, 1989, v. 16, n. 3, p. 321, doi. 10.1080/02664768900000040

By:

Chuang-Stein, Christy;
Weaver, R. John

Publication type:

Article

Some simple log-linear models for the analysis of ordinal response data.

Published in:

Journal of Applied Statistics, 1988, v. 15, n. 3, p. 285, doi. 10.1080/02664768800000039

By:

Chuang-Stein, Christy;
Francom, Steven F.

Publication type:

Article

Challenge of multiple co-primary endpoints: a new approach.

Published in:

Statistics in Medicine, 2007, v. 26, n. 6, p. 1181, doi. 10.1002/sim.2604

By:

Chuang-Stein, Christy;
Stryszak, Paul;
Dmitrienko, Alex;
Offen, Walter

Publication type:

Article

Discussion.

Published in:

Statistics in Medicine, 2006, v. 25, n. 19, p. 3297, doi. 10.1002/sim.2643

By:

Chuang-Stein, Christy

Publication type:

Article

Tutorial in Biostatistics A review of tests for detecting a monotone dose-response relationship with ordinal response data.

Published in:

Statistics in Medicine, 1997, v. 16, n. 22, p. 2599, doi. 10.1002/(SICI)1097-0258(19971130)16:22<2599::AID-SIM734>3.0.CO;2-9

By:

Chuang-Stein, Christy;
Agresti, Alan

Publication type:

Article

Adaptivity in drug discovery and development.

Published in:

Drug Development Research, 2009, v. 70, n. 3, p. 169, doi. 10.1002/ddr.20285

By:

Bretz, Frank;
Branson, Michael;
Burman, Carl-Fredrik;
Chuang-Stein, Christy;
Coffey, Christopher S.

Publication type:

Article

Celebrating the 175th Anniversary of ASA.

Published in:

American Statistician, 2015, v. 69, n. 2, p. 64, doi. 10.1080/00031305.2015.1028765

By:

Chuang-Stein, Christy;
Balakrishnan, Narayanaswamy;
Berzofsky, Marcus;
Herring, Amy;
Hulting, Fred;
McKenzie, John;
Price, Dionne;
Stigler, Stephen;
Williams, George;
Wasserstein, Ronald

Publication type:

Article

Implementation of AMNOG: An industry perspective.

Published in:

Biometrical Journal, 2016, v. 58, n. 1, p. 76, doi. 10.1002/bimj.201300256

By:

Leverkus, Friedhelm;
Chuang‐Stein, Christy

Publication type:

Article

The Practice of Pre-Marketing Safety Assessment in Drug Development.

Published in:

Journal of Biopharmaceutical Statistics, 2013, v. 23, n. 1, p. 3, doi. 10.1080/10543406.2013.736805

By:

Chuang-Stein, Christy;
Xia, H.Amy

Publication type:

Article

Designing Studies to Find Early Signals of Efficacy.

Published in:

Journal of Biopharmaceutical Statistics, 2012, v. 22, n. 6, p. 1097, doi. 10.1080/10543406.2011.570466

By:

Brown, MichaelJ.;
Chuang-Stein, Christy;
Kirby, Simon

Publication type:

Article

Viewpoints on the FDA Draft Adaptive Designs Guidance from the PhRMA Working Group.

Published in:

Journal of Biopharmaceutical Statistics, 2010, v. 20, n. 6, p. 1115, doi. 10.1080/10543406.2010.514452

By:

Gallo, Paul;
Anderson, Keaven;
Chuang-Stein, Christy;
Dragalin, Vladimir;
Gaydos, Brenda;
Krams, Michael;
Pinheiro, José

Publication type:

Article

FDA Draft Guidance on Adaptive Design Clinical Trials: Pfizer's Perspective.

Published in:

Journal of Biopharmaceutical Statistics, 2010, v. 20, n. 6, p. 1143, doi. 10.1080/10543406.2010.514456

By:

Chuang-Stein, Christy;
Beltangady, Mohan

Publication type:

Article

Determining a Minimum Clinically Important Difference Between Treatments for a Patient-Reported Outcome.

Published in:

Journal of Biopharmaceutical Statistics, 2010, v. 20, n. 5, p. 1043, doi. 10.1080/10543400903315757

By:

Kirby, Simon;
Chuang-Stein, Christy;
Morris, Mark

Publication type:

Article

Discussion of “Some Controversial Multiple Testing Problems in Regulatory Applications”.

Published in:

Journal of Biopharmaceutical Statistics, 2009, v. 19, n. 1, p. 14, doi. 10.1080/10543400802541719

By:

Chuang-stein, Christy;
Dmitrienko, Alex;
Offen, Walter

Publication type:

Article