Works matching AU Chua, Streamson

Results: 46

Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.

Published in:

2011

By:

Donato Jr., Jose;
Cravo, Roberta M.;
Frazão, Renata;
Gautron, Laurent;
Scott, Michael M.;
Lachey, Jennifer;
Castro, Inar A.;
Margatho, Lisandra O.;
Lee, Syann;
Lee, Charlotte;
Richardson, James A.;
Friedman, Jeffrey;
Chua Jr., Streamson;
Coppari, Roberto;
Zigman, Jeffrey M.;
Elmquist, Joel K.;
Elias, Carol F.;
Donato, Jose Jr;
Frazão, Renata;
Chua, Streamson Jr

Publication type:

journal article

Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes.

Published in:

2005

By:

de Luca, Carl;
Kowalski, Timothy J.;
Yiying Zhang;
Elmquist, Joel K.;
Charlotte Lee;
Kilimann, Manfred W.;
Ludwig, Thomas;
Shun-Mei Liu;
Chua, Jr., Streamson C.;
Zhang, Yiying;
Lee, Charlotte;
Liu, Shun-Mei;
Chua, Streamson C Jr

Publication type:

journal article

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56328-5

By:

Hwang, Jiyeon;
Lee, Sangbhin;
Okada, Junichi;
Liu, Li;
Pessin, Jeffrey E.;
Chua Jr, Streamson C.;
Schwartz, Gary J.;
Jo, Young-Hwan

Publication type:

Article

Regulation of Hypothalamic Proopiomelanocortin by Leptin in Lean and Obese Rats.

Published in:

Neuroendocrinology, 1999, v. 70, n. 6, p. 377, doi. 10.1159/000054499

By:

Korner, Judith;
Chua Jr., Streamson C.;
Williams, Julie A.;
Leibel, Rudolph L.;
Wardlaw, Sharon L.

Publication type:

Article

A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children.

Published in:

2011

By:

Duggal, Priya;
Xiaoti Guo;
Haque, Rashidul;
Peterson, Kristine M.;
Ricklefs, Stacy;
Mondal, Dinesh;
Alam, Faisal;
Noor, Zannatun;
Verkerke, Hans P.;
Marie, Chelsea;
Leduc, Charles A.;
Chua Jr., Streamson C.;
Myers Jr., Martin G.;
Leibel, Rudolph L.;
Houpt, Eric;
Gilchrist, Carol A.;
Sher, Alan;
Porcella, Stephen F.;
Petri Jr., William A.;
Guo, Xiaoti

Publication type:

journal article

Functional Consequences of the Human Leptin Receptor (LEPR) Q223R Transversion.

Published in:

Obesity (19307381), 2009, v. 17, n. 1, p. 126, doi. 10.1038/oby.2008.489

By:

Stratigopoulos, George;
LeDuc, Charles A.;
Matsuoka, Naoki;
Gutman, Roee;
Rausch, Richard;
Robertson, Scott A.;
Myers Jr., Martin G.;
Chung, Wendy K.;
Chua Jr., Streamson C.;
Leibel, Rudolph L.

Publication type:

Article

Food Deprivation Modulates Neuropeptide Y Gene Expression in the Murine Hypothalamus.

Published in:

Annals of the New York Academy of Sciences, 1990, v. 611, n. 1, p. 477, doi. 10.1111/j.1749-6632.1990.tb48990.x

By:

CHUA, STREAMSON C.

Publication type:

Article

The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity.

Published in:

Journal of Cell Biology, 2008, v. 183, n. 7, p. 1235, doi. 10.1083/jcb.200809113

By:

Hinoi, Eiichi;
Gao, Nan;
Jung, Dae Young;
Yadav, Vijay;
Yoshizawa, Tatsuya;
Myers Jr., Martin G.;
Chua Jr., Streamson C.;
Kim, Jason K.;
Kaestner, Klaus H.;
Karsenty, Gerard

Publication type:

Article

FGF 19 and Bile Acids Increase Following Roux-en-Y Gastric Bypass but Not After Medical Management in Patients with Type 2 Diabetes.

Published in:

Obesity Surgery, 2016, v. 26, n. 5, p. 957, doi. 10.1007/s11695-015-1834-0

By:

Sachdev, Saachi;
Wang, Qi;
Billington, Charles;
Connett, John;
Ahmed, Leaque;
Inabnet, William;
Chua, Streamson;
Ikramuddin, Sayeed;
Korner, Judith

Publication type:

Article

Coordinated Regulation of Hepatic Energy Stores by Leptin and Hypothalamic Agouti-Related Protein.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 29, p. 11972, doi. 10.1523/JNEUROSCI.0830-13.2013

By:

Warne, James P.;
Varonin, Jillian M.;
Nielsen, Sofie S.;
Olofsson, Louise E.;
Kaelin, Christopher B.;
Chua Jr., Streamson;
Barsh, Gregory S.;
Koliwad, Suneil K.;
Xu, Allison W.

Publication type:

Article

TXNIP in Agrp Neurons Regulates Adiposity, Energy Expenditure, and Central Leptin Sensitivity.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 29, p. 9870, doi. 10.1523/JNEUROSCI.0353-12.2012

By:

Blouet, Clemence;
Shun-Mei Liu;
Young-Hwan Jo;
Chua, Streamson;
Schwartz, Gary J.

Publication type:

Article

CNS Leptin Action Modulates Immune Response and Survival in Sepsis.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 17, p. 6036, doi. 10.1523/JNEUROSCI.4875-09.2010

By:

Tschöp, Johannes;
Nogueiras, Ruben;
Haas-Lockie, Sarah;
Kasten, Kevin R.;
Castañeda, Tamara R.;
Huber, Nadine;
Guanciale, Kelsey;
Perez-Tilve, Diego;
Habegger, Kirk;
Ottaway, Nickki;
Woods, Stephen C.;
Oldfield, Brian;
Clarke, Iain;
Chua Jr., Streamson;
Sadaf Farooqi, I.;
O'Rahilly, Stephen;
Caldwell, Charles C.;
Tschöp, Matthias H.

Publication type:

Article

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 6, p. 17, doi. 10.1128/MCB.01300-08

By:

Khan, Tayeba;
Muise, Eric S.;
Iyengar, Puneeth;
Wang, Zhao V.;
Chandalia, Manisha;
Abate, Nicola;
Zhang, Bei B.;
Bonaldo, Paolo;
Chua, Streamson;
Scherer, Philipp E.

Publication type:

Article

Selective deletion of leptin receptors in adult hippocampus induces depression-related behaviours.

Published in:

International Journal of Neuropsychopharmacology, 2013, v. 16, n. 4, p. 857, doi. 10.1017/S1461145712000703

By:

Ming Guo;
Huang, Tung-Yi;
Garza, Jacob C.;
Chua, Streamson C.;
Lu, Xin-Yun

Publication type:

Article

Interplay between glucose and leptin signalling determines the strength of GABAergic synapses at POMC neurons.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 6618, doi. 10.1038/ncomms7618

By:

Lee, Dong Kun;
Jeong, Jae Hoon;
Chun, Sung-Kun;
Chua Jr., Streamson;
Jo, Young-Hwan

Publication type:

Article

An Osteoblast-dependent Mechanism Contributes to the Leptin Regulation of Insulin Secretion.

Published in:

Annals of the New York Academy of Sciences, 2009, v. 1173, p. E20, doi. 10.1111/j.1749-6632.2009.05061.x

By:

Hinoi, Eiichi;
Gao, Nan;
Jung, Dae Young;
Yadav, Vijay;
Yoshizawa, Tatsuya;
Kajimura, Daisuke;
Myers, Jr., Martin G.;
Chua, Jr., Streamson C.;
Wang, Qin;
Kim, Jason K.;
Kaestner, Klaus H.;
Karsenty, Gerard

Publication type:

Article

Perspectives on Adipose Tissue, Chagas Disease and Implications for the Metabolic Syndrome.

Published in:

Interdisciplinary Perspectives on Infectious Diseases, 2009, p. 1, doi. 10.1155/2009/824324

By:

Nagajyothi, Fnu;
Desruisseaux, Mahalia S.;
Jelicks, Linda A.;
Machado, Fabiana S.;
Chua, Streamson;
Scherer, Philipp E.;
Tanowitz, Herbert B.

Publication type:

Article

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake.

Published in:

Nature Medicine, 2006, v. 12, n. 5, p. 534, doi. 10.1038/nm1392

By:

Kitamura, Tadahiro;
Yun Feng;
Ido Kitamura, Yukari;
Chua, Streamson C.;
Xu, Allison W.;
Barsh, Gregory S.;
Rossetti, Luciano;
Accili, Domenico

Publication type:

Article

pRb is an obesity suppressor in hypothalamus and high-fat diet inhibits pRb in this location.

Published in:

EMBO Journal, 2013, v. 32, n. 6, p. 844, doi. 10.1038/emboj.2013.25

By:

Lu, Zhonglei;
Marcelin, Genevieve;
Bauzon, Frederick;
Wang, Hongbo;
Fu, Hao;
Dun, Siok Le;
Zhao, Hongling;
Li, Xiaosong;
Jo, Young‐Hwan;
Wardlaw, Sharon;
Dun, Nae;
Chua, Streamson;
Zhu, Liang

Publication type:

Article

Intestinal deletion of leptin signaling alters activity of nutrient transporters and delayed the onset of obesity in mice.

Published in:

FASEB Journal, 2014, v. 28, n. 9, p. 4100, doi. 10.1096/fj.14-255158

By:

Tavernier, Annabelle;
Cavin, Jean-Baptiste;
Le Gall, Maude;
Ducroc, Robert;
Denis, Raphael G. P.;
Cluzeaud, Francoise;
Guilmeau, Sandra;
Sakar, Yassine;
Barbot, Laurence;
Kapel, Nathalie;
Le Beyec, Johanne;
Joly, Francisca;
Chua, Streamson;
Luquet, Serge;
Bado, Andre

Publication type:

Article

Adipose-Selective Overexpression of CGI-58 Does Not Alter Lipolysis or Protect Against Diet-Induced Obesity.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A704

By:

Dapito, Dianne-Helerie;
Caviglia, Jorge Matias;
Chua, Streamson;
Sekowski, Anna;
Yin, Terry;
Haiyan Mu;
Shapiro, Lawrence;
Brasaemle, Dawn L.

Publication type:

Article

Identification of a Loss-of-Function Mutation in Ube216 Associated With Obesity Resistance.

Published in:

Diabetes, 2013, v. 62, n. 8, p. 2784, doi. 10.2337/db12-1054

By:

Marcelin, Genevieve;
Shun-Mei Liu;
Schwartz, Gary J.;
Chua Jr., Streamson C.

Publication type:

Article

The Brain-Liver Connection Between BDNF and Glucose Control.

Published in:

Diabetes, 2013, v. 62, n. 5, p. 1367, doi. 10.2337/db12-1824

By:

Young-Hwan Jo;
Chua Jr., Streamson C.

Publication type:

Article

The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival.

Published in:

Diabetes, 2013, v. 62, n. 1, p. 183, doi. 10.2337/db12-0504

By:

McKimpson, Wendy M.;
Weinberger, Jeremy;
Czerski, Lech;
Min Zheng;
Crow, Michael T.;
Pessin, Jeffrey E.;
Chua Jr., Streamson C.;
Kitsis, Richard N.

Publication type:

Article

Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance.

Published in:

Diabetes, 2010, v. 59, n. 12, p. 3032, doi. 10.2337/db10-0074

By:

Huynh, Frank K.;
Levi, Jasna;
Denroche, Heather C.;
Gray, Sarah L.;
Voshol, Peter J.;
Neumann, Ursula H.;
Speck, Madeleine;
Chua, Streamson C.;
Covey, Scott D.;
Kieffer, Timothy J.

Publication type:

Article

Signal Transduction Pathways for Leptin.

Published in:

2009

By:

Chua, Jr., Streamson

Publication type:

Opinion

Signal transduction pathways for leptin: an embarrassment of riches.

Published in:

2009

By:

Chua S Jr;
Chua, Streamson Jr

Publication type:

journal article

Diabetes Modifier Genes that Affect β Cell Proliferation.

Published in:

Diabetes, 2007, v. 56, p. A103

By:

Luo, Na;
Li, Qiong;
Chua Jr., Streamson

Publication type:

Article

Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes.

Published in:

2005

By:

Wang Z;
Jiang T;
Li J;
Proctor G;
McManaman JL;
Lucia S;
Chua S;
Levi M;
Wang, Zhuowei;
Jiang, Tao;
Li, Jinping;
Proctor, Gregory;
McManaman, James L;
Lucia, Scott;
Chua, Streamson;
Levi, Moshe

Publication type:

journal article

Regulation of Renal Lipid Metabolism, Lipid Accumulation, and Glomerulosclerosis in FVB<sup>db/db</sup> Mice With Type 2 Diabetes.

Published in:

Diabetes, 2005, v. 54, n. 8, p. 2328, doi. 10.2337/diabetes.54.8.2328

By:

Wang, Zhuowei;
Jiang, Tao;
Li, Jinping;
Proctor, Gregory;
McManaman, James L.;
Lucia, Scott;
Chua, Streamson;
Levi, Moshe

Publication type:

Article

Transgenic Complementation of Leptin-Receptor Deficiency.

Published in:

Diabetes, 2001, v. 50, n. 2, p. 425, doi. 10.2337/diabetes.50.2.425

By:

Kowalski, Timothy J.;
Shun-Mei Liu;
Leibel, Rudolph L.;
Chua, Jr., Streamson C.

Publication type:

Article

Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat.

Published in:

1997

By:

Wu-Peng, X. Sharon;
Chua Jr., Streamson C.;
Okada, Norichika;
Shun-Mei Liu;
Nicolson, Margery;
Leibel, Rudolph L.;
Wu-Peng, X S;
Chua, S C Jr;
Okada, N;
Liu, S M;
Nicolson, M;
Leibel, R L

Publication type:

journal article

Absence of Linkage of Obesity and Energy Metabolism to Markers Flanking Homologues of Rodent Obesity Genes in Pima Indians.

Published in:

Diabetes, 1996, v. 45, n. 9, p. 1229, doi. 10.2337/diab.45.9.1229

By:

Norman, Rod A.;
Leibel, Rudolph L.;
Chung, Wendy K.;
Power-Kehoe, Loraine;
Chua, Jr., Streamson C.;
Knowler, William C.;
Thompson, D. Bruce;
Bogardus, Clifton;
Ravussin, Eric

Publication type:

Article

Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

Published in:

1996

By:

Chua Jr., Streamson C.;
White, David W.;
Wu-Peng, X. Sharon;
Shun-Mei Liu;
Okada, Norichika;
Kershaw, Erin E.;
Chung, Wendy K.;
Power-Kehoe, Loraine;
Chua, Melvin;
Tartaglia, Louis A.;
Leibel, Rudolph L.;
Chua, S C Jr;
White, D W;
Wu-Peng, X S;
Liu, S M;
Okada, N;
Kershaw, E E;
Chung, W K;
Power-Kehoe, L;
Chua, M

Publication type:

journal article

Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-20160-w

By:

Kwon, Eunjin;
Joung, Hye-Young;
Liu, Shun-Mei;
Chua, Streamson C.;
Schwartz, Gary J.;
Jo, Young-Hwan

Publication type:

Article

The Antidepressant <i>Trans</i>-2-Phenylcyclopropylamine Protects Mice from High-Fat-Diet-Induced Obesity.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089199

By:

Shemesh, Adi;
Abdulla, Arian;
Yang, Fajun;
Chua, Streamson C.;
Pessin, Jeffrey E.;
Zong, Haihong

Publication type:

Article

Adipocyte Dysfunction in a Mouse Model of Polycystic Ovary Syndrome (PCOS): Evidence of Adipocyte Hypertrophy and Tissue-Specific Inflammation.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0048643

By:

Marino, Joseph S.;
Iler, Jeffrey;
Dowling, Abigail R.;
Chua, Streamson;
Bruning, Jens C.;
Coppari, Roberto;
Hill, Jennifer W.

Publication type:

Article

An allelic series for the leptin receptor gene generated by CRE and FLP recombinase.

Published in:

Mammalian Genome, 2004, v. 15, n. 9, p. 677, doi. 10.1007/s00335-004-2340-1

By:

McMinn, Julie;
Liu, Shun-Mei;
Dragatsis, Ioannis;
Dietrich, Paula;
Ludwig, Thomas;
Eiden, Sandra;
Chua, Jr., Streamson

Publication type:

Article

mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.22848

By:

Burke, Luke K.;
Darwish, Tamana;
Cavanaugh, Althea R.;
Virtue, Sam;
Roth, Emma;
Morro, Joanna;
Shun-Mei Liu;
Jing Xia;
Dalley, Jeffrey W.;
Burling, Keith;
Chua, Streamson;
Vidal-Puig, Toni;
Schwartz, Gary J.;
Blouet, Clémence

Publication type:

Article

Monogenic Models of Obesity.

Published in:

Behavior Genetics, 1997, v. 27, n. 4, p. 277, doi. 10.1023/A:1025679728948

By:

Chua Jr., Streamson C.

Publication type:

Article

Response of Adipose Tissue to Early Infection With Trypanosoma cruzi (Brazil Strain).

Published in:

Journal of Infectious Diseases, 2012, v. 205, n. 5, p. 830, doi. 10.1093/infdis/jir840

By:

Nagajyothi, Fnu;
Desruisseaux, Mahalia S.;
Machado, Fabiana S.;
Upadhya, Rajendra;
Dazhi Zhao;
Schwartz, Gary J.;
Teixeira, Mauro M.;
Albanese, Chris;
Lisanti, Michael P.;
Chua Jr., Streamson C.;
Weiss, Louis M.;
Scherer, Philipp E.;
Tanowitz, Herbert B.

Publication type:

Article

Crucial Role of the Central Leptin Receptor in Murine Trypanosoma cruzi (Brazil Strain) Infection.

Published in:

Journal of Infectious Diseases, 2010, v. 202, n. 7, p. 1104, doi. 10.1086/656189

By:

Nagajyothi, Fnu;
Zhao, Dazhi;
Machado, Fabiana S.;
Weiss, Louis M.;
Schwartz, Gary J.;
Desruisseaux, Mahalia S.;
Yang Zhao;
Factor, Stephen M.;
Huan Huang;
Albanese, Chris;
Teixeira, Mauro M.;
Scherer, Philipp E.;
Chua, Jr,, Streamson C.;
Tanowitz, Herbert B.

Publication type:

Article

RESPONSE.

Published in:

JNCI: Journal of the National Cancer Institute, 2003, v. 95, n. 14, p. 1087

By:

Hsing, Ann;
Chua Jr., Streamson

Publication type:

Article

Insulin Resistance and Prostate Cancer Risk.

Published in:

JNCI: Journal of the National Cancer Institute, 2003, v. 95, n. 1, p. 67, doi. 10.1093/jnci/95.1.67

By:

Hsing, Ann W.;
Yu-Tang Gao;
Chua Jr., Streamson;
Jie Deng;
Stanczyk, Frank Z.

Publication type:

Article

Prostate Cancer Risk and Serum Levels of Insulin and Leptin: a Population-Based Study.

Published in:

JNCI: Journal of the National Cancer Institute, 2001, v. 93, n. 10, p. 782, doi. 10.1093/jnci/93.10.783

By:

Hsing, Ann W.;
Chua Jr., Streamson;
Yu-Tang Gao;
Gentzschein, Elisabeth;
Chang, Lilly;
Jie Deng;
Stanczyk, Frank Z.

Publication type:

Article

A susceptibility gene for kidney disease in an obese mouse model of type II diabetes maps to chromosome 8.

Published in:

Kidney International, 2010, v. 78, n. 5, p. 453, doi. 10.1038/ki.2010.160

By:

Chua, Jr., Streamson;
Yifu Li;
Shun Mei Liu;
Ruijie Liu;
Ka Tak Chan;
Martino, Jeremiah;
Zongyu Zheng;
Susztak, Katalin;
D'Agati, Vivette D.;
Gharavi, Ali G.

Publication type:

Article