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Segregation, immunohistochemical, molecular and functional analyses classify a novel missense variant in fumarate hydratase (FH) as pathogenic.
- Published in:
- Genes, Chromosomes & Cancer, 2024, v. 63, n. 2, p. 1, doi. 10.1002/gcc.23221
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- Article
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
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- Nature Communications, 2016, v. 7, n. 4, p. 11457, doi. 10.1038/ncomms11457
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- Article
MYC-induced reprogramming of glutamine catabolism supports optimal virus replication.
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- Nature Communications, 2015, v. 6, n. 11, p. 8873, doi. 10.1038/ncomms9873
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- Article
Pyruvate kinase M2 is a phosphotyrosine-binding protein.
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- Nature, 2008, v. 452, n. 7184, p. 181, doi. 10.1038/nature06667
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- Article
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
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- Nature, 2008, v. 452, n. 7184, p. 230, doi. 10.1038/nature06734
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- Article
Viral hijacking of cellular metabolism.
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- BMC Biology, 2019, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12915-019-0678-9
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- Article
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis.
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- eLife, 2017, p. 1, doi. 10.7554/eLife.29330
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- Article
Fast Metabolic Response to Drug Intervention Through Analysis on a Miniaturized, Highly Integrated Molecular Imaging System.
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- Journal of Nuclear Medicine, 2013, v. 54, n. 10, p. 1820, doi. 10.2967/jnumed.112.118497
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- Article
SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22166-4
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- Article
Doxycycline Alters Metabolism and Proliferation of Human Cell Lines
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064561
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- Article
Fumarate hydratase variant prevalence and manifestations among individuals receiving germline testing.
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- Cancer (0008543X), 2022, v. 128, n. 4, p. 675, doi. 10.1002/cncr.33997
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- Article
A label-free quantification method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen.
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- Proteomics, 2008, v. 8, n. 5, p. 994, doi. 10.1002/pmic.200700426
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- Article
Cancer: A metabolic metamorphosis.
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- Nature, 2013, v. 496, n. 7443, p. 38, doi. 10.1038/496038a
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- Article
Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities.
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- Cancer & Metabolism, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40170-018-0177-4
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- Article
Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer.
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- Journal of Cancer Research & Clinical Oncology, 2014, v. 140, n. 3, p. 443, doi. 10.1007/s00432-014-1583-9
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- Article
GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88159-x
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- Article
Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma.
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- Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-016-0305-0
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- Article