Works by Chowdhury, Rasheduzzaman

Results: 39

Substrate Selectivity Analyses of Factor Inhibiting Hypoxia-Inducible Factor.

Published in:

Angewandte Chemie, 2013, v. 125, n. 6, p. 1744, doi. 10.1002/ange.201208046

By:

Yang, Ming;
Hardy, Adam P.;
Chowdhury, Rasheduzzaman;
Loik, Nikita D.;
Scotti, John S.;
McCullagh, James S. O.;
Claridge, Timothy D. W.;
McDonough, Michael A.;
Ge, Wei;
Schofield, Christopher J.

Publication type:

Article

Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors.

Published in:

Angewandte Chemie, 2012, v. 124, n. 27, p. 6776, doi. 10.1002/ange.201202000

By:

Demetriades, Marina;
Leung, Ivanhoe K. H.;
Chowdhury, Rasheduzzaman;
Chan, Mun Chiang;
McDonough, Michael A.;
Yeoh, Kar Kheng;
Tian, Ya-Min;
Claridge, Timothy D. W.;
Ratcliffe, Peter J.;
Woon, Esther C. Y.;
Schofield, Christopher J.

Publication type:

Article

Evidence for a Stereoelectronic Effect in Human Oxygen Sensing.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 10, p. 1784, doi. 10.1002/anie.200805427

By:

Loenarz, Christoph;
Mecinović, Jasmin;
Chowdhury, Rasheduzzaman;
McNeill, Luke A.;
Flashman, Emily;
Schofield, Christopher J.

Publication type:

Article

SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-12449-1

By:

Song, Chunying;
Liu, Dong;
Liu, Suxing;
Li, Di;
Horecny, Ivana;
Zhang, Xinzhu;
Li, Puhui;
Chen, Lei;
Miller, Matthew;
Chowdhury, Rasheduzzaman;
Issa, Mena;
Shen, Ru;
Yan, Yinfa;
Zhang, Fengqi;
Zhang, Lei;
Zhang, Limin;
Bai, Chang;
Feng, Jun;
Zhuang, Linghang;
Zhang, Rumin

Publication type:

Article

Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10028-y

By:

Chowdhury, Rasheduzzaman;
Abboud, Martine I.;
Wiley, James;
Tumber, Anthony;
Markolovic, Suzana;
Schofield, Christopher J.

Publication type:

Article

Bioactivity of Extractives from Stachytarpheta urticaefolia.

Published in:

Pharmaceutical Biology, 2004, v. 42, n. 3, p. 262, doi. 10.1080/13880200490514203

By:

Chowdhury, Rasheduzzaman;
Rashid, Mamun Ur;
Khan, Omar Faruk;
Hasan, Choudhury

Publication type:

Article

Bioactivity from Toona ciliata Stem Bark.

Published in:

Pharmaceutical Biology, 2003, v. 41, n. 4, p. 281, doi. 10.1076/phbi.41.4.281.15662

By:

Chowdhury, Rasheduzzaman;
Hasan, Choudhury M.;
Rashid, Mohammad A.

Publication type:

Article

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132004

By:

Chan, Mun Chiang;
Atasoylu, Onur;
Hodson, Emma;
Tumber, Anthony;
Leung, Ivanhoe K. H.;
Chowdhury, Rasheduzzaman;
Gómez-Pérez, Verónica;
Demetriades, Marina;
Rydzik, Anna M.;
Holt-Martyn, James;
Tian, Ya-Min;
Bishop, Tammie;
Claridge, Timothy D. W.;
Kawamura, Akane;
Pugh, Christopher W.;
Ratcliffe, Peter J.;
Schofield, Christopher J.

Publication type:

Article

Publisher Correction: JMJD5 is a human arginyl C-3 hydroxylase.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04196-7

By:

Wilkins, Sarah E.;
Islam, Md. Saiful;
Gannon, Joan M.;
Markolovic, Suzana;
Hopkinson, Richard J.;
Wei Ge;
Schofield, Christopher J.;
Chowdhury, Rasheduzzaman

Publication type:

Article

JMJD5 is a human arginyl C-3 hydroxylase.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03410-w

By:

Wilkins, Sarah E.;
Islam, Md. Saiful;
Gannon, Joan M.;
Markolovic, Suzana;
Hopkinson, Richard J.;
Wei Ge;
Schofield, Christopher J.;
Chowdhury, Rasheduzzaman

Publication type:

Article

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.

Published in:

EMBO Reports, 2011, v. 12, n. 5, p. 463, doi. 10.1038/embor.2011.43

By:

Chowdhury, Rasheduzzaman;
Yeoh, Kar Kheng;
Tian, Ya-Min;
Hillringhaus, Lars;
Bagg, Eleanor A;
Rose, Nathan R;
Leung, Ivanhoe K H;
Li, Xuan S;
Woon, Esther C Y;
Yang, Ming;
McDonough, Michael A;
King, Oliver N;
Clifton, Ian J;
Klose, Robert J;
Claridge, Timothy D W;
Ratcliffe, Peter J;
Schofield, Christopher J;
Kawamura, Akane

Publication type:

Article

A human protein hydroxylase that accepts D-residues.

Published in:

Communications Chemistry, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42004-020-0290-5

By:

Choi, Hwanho;
Hardy, Adam P.;
Leissing, Thomas M.;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Ge, Wei;
Markoulides, Marios;
Scotti, John S.;
Gerken, Philip A.;
Thorbjornsrud, Helen;
Kang, Dahye;
Hong, Sungwoo;
Lee, Joongoo;
McDonough, Michael A.;
Park, Hwangseo;
Schofield, Christopher J.

Publication type:

Article

Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-76307-8

By:

Chowdhury, Rasheduzzaman;
Abboud, Martine I.;
McAllister, Tom E.;
Banerji, Biswadip;
Bhushan, Bhaskar;
Sorensen, John L.;
Kawamura, Akane;
Schofield, Christopher J.

Publication type:

Article

Mechanistic and structural studies of KDM‐catalysed demethylation of histone 1 isotype 4 at lysine 26.

Published in:

FEBS Letters, 2018, v. 592, n. 19, p. 3264, doi. 10.1002/1873-3468.13231

By:

Walport, Louise J.;
Hopkinson, Richard J.;
Chowdhury, Rasheduzzaman;
Zhang, Yijia;
Bonnici, Joanna;
Schiller, Rachel;
Kawamura, Akane;
Schofield, Christopher J.

Publication type:

Article

A Convenient Synthesis of New Annelated Pyrimidines and Their Biological Importance.

Published in:

Journal of Heterocyclic Chemistry, 2014, v. 51, p. E216, doi. 10.1002/jhet.1891

By:

Wahab Khan, M.;
Uddin, Mohammed Kabir;
Ali, Morshed;
Rahman, Mohammad S.;
Rashid, Mohammad Abdur;
Chowdhury, Rasheduzzaman

Publication type:

Article

Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.

Published in:

Angewandte Chemie, 2021, v. 133, n. 26, p. 14778, doi. 10.1002/ange.202103711

By:

Brasnett, Amelia;
Pfeffer, Inga;
Brewitz, Lennart;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Tumber, Anthony;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.

Published in:

Nature Communications, 2017, v. 8, n. 4, p. 14773, doi. 10.1038/ncomms14773

By:

Kawamura, Akane;
Münzel, Martin;
Kojima, Tatsuya;
Yapp, Clarence;
Bhushan, Bhaskar;
Goto, Yuki;
Tumber, Anthony;
Katoh, Takayuki;
King, Oliver N. F.;
Passioura, Toby;
Walport, Louise J.;
Hatch, Stephanie B.;
Madden, Sarah;
Müller, Susanne;
Brennan, Paul E.;
Chowdhury, Rasheduzzaman;
Hopkinson, Richard J.;
Suga, Hiroaki;
Schofield, Christopher J.

Publication type:

Article

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.

Published in:

Nature Communications, 2016, v. 7, n. 8, p. 12673, doi. 10.1038/ncomms12673

By:

Chowdhury, Rasheduzzaman;
Leung, Ivanhoe K. H.;
Tian, Ya-Min;
Abboud, Martine I.;
Ge, Wei;
Domene, Carmen;
Cantrelle, François-Xavier;
Landrieu, Isabelle;
Hardy, Adam P.;
Pugh, Christopher W.;
Ratcliffe, Peter J.;
Claridge, Timothy D. W.;
Schofield, Christopher J.

Publication type:

Article

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 11974, doi. 10.1038/ncomms11974

By:

Walport, Louise J.;
Hopkinson, Richard J.;
Chowdhury, Rasheduzzaman;
Schiller, Rachel;
Ge, Wei;
Kawamura, Akane;
Schofield, Christopher J.

Publication type:

Article

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.

Published in:

Nature Chemical Biology, 2012, v. 8, n. 12, p. 960, doi. 10.1038/nchembio.1093

By:

Ge, Wei;
Wolf, Alexander;
Feng, Tianshu;
Ho, Chia-hua;
Sekirnik, Rok;
Zayer, Adam;
Granatino, Nicolas;
Cockman, Matthew E;
Loenarz, Christoph;
Loik, Nikita D;
Hardy, Adam P;
Claridge, Timothy D W;
Hamed, Refaat B;
Chowdhury, Rasheduzzaman;
Gong, Lingzhi;
Robinson, Carol V;
Trudgian, David C;
Jiang, Miao;
Mackeen, Mukram M;
Mccullagh, James S

Publication type:

Article

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.

Published in:

FEBS Journal, 2011, v. 278, n. 7, p. 1086, doi. 10.1111/j.1742-4658.2011.08022.x

By:

Yang, Ming;
Chowdhury, Rasheduzzaman;
Ge, Wei;
Hamed, Refaat B.;
McDonough, Michael A.;
Claridge, Timothy D. W.;
Kessler, Benedikt M.;
Cockman, Matthew E.;
Ratcliffe, Peter J.;
Schofield, Christopher J.

Publication type:

Article

Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 26, p. 14657, doi. 10.1002/anie.202103711

By:

Brasnett, Amelia;
Pfeffer, Inga;
Brewitz, Lennart;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Tumber, Anthony;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

The oxygenase Jmjd6 - a case study in conflicting assignments.

Published in:

2015

By:

Böttger, Angelika;
Islam, Md. Saiful;
Chowdhury, Rasheduzzaman;
Schofield, J.;
Wolf, Alexander

Publication type:

Case Study

Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen.

Published in:

Biochemical Journal, 2014, v. 463, n. 3, p. 363, doi. 10.1042/BJ20140779

By:

TARHONSKAYA, Hanna;
CHOWDHURY, Rasheduzzaman;
LEUNG, Ivanhoe K. H.;
LOIK, Nikita D.;
MCCULLAGH, James S. O.;
CLARIDGE, Timothy D. W.;
SCHOFIELD, Christopher J.;
FLASHMAN, Emily

Publication type:

Article

Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-24154-0

By:

Islam, Md. Saiful;
Markoulides, Marios;
Chowdhury, Rasheduzzaman;
Schofield, Christopher J.

Publication type:

Article

Diagnosis for COVID-19: current status and future prospects.

Published in:

Expert Review of Molecular Diagnostics, 2021, v. 21, n. 3, p. 269, doi. 10.1080/14737159.2021.1894930

By:

Kabir, MD Alamgir;
Ahmed, Rajib;
Iqbal, Sheikh Muhammad Asher;
Chowdhury, Rasheduzzaman;
Paulmurugan, Ramasamy;
Demirci, Utkan;
Asghar, Waseem

Publication type:

Article

Studies on the Substrate Selectivity of the Hypoxia‐Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain.

Published in:

ChemBioChem, 2018, v. 19, n. 21, p. 2262, doi. 10.1002/cbic.201800246

By:

Abboud, Martine I.;
Chowdhury, Rasheduzzaman;
Leung, Ivanhoe K. H.;
Lippl, Kerstin;
Loenarz, Christoph;
Claridge, Timothy D. W.;
Schofield, Christopher J.

Publication type:

Article

Ribosomal oxygenases are structurally conserved from prokaryotes to humans.

Published in:

Nature, 2014, v. 510, n. 7505, p. 422, doi. 10.1038/nature13263

By:

Chowdhury, Rasheduzzaman;
Sekirnik, Rok;
Brissett, Nigel C.;
Krojer, Tobias;
Ho, Chia-hua;
Ng, Stanley S.;
Clifton, Ian J.;
Ge, Wei;
Kershaw, Nadia J.;
Fox, Gavin C.;
Muniz, Joao R. C.;
Vollmar, Melanie;
Phillips, Claire;
Pilka, Ewa S.;
Kavanagh, Kathryn L.;
von Delft, Frank;
Oppermann, Udo;
McDonough, Michael A.;
Doherty, Aidan J.;
Schofield, Christopher J.

Publication type:

Article

Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.884399

By:

Zhou, Yu;
Li, Xin;
Shen, Ru;
Wang, Xiangzhu;
Zhang, Fan;
Liu, Suxing;
Li, Di;
Liu, Jian;
Li, Puhui;
Yan, Yinfa;
Dong, Ping;
Zhang, Zhigao;
Wu, Heping;
Zhuang, Linghang;
Chowdhury, Rasheduzzaman;
Miller, Matthew;
Issa, Mena;
Mao, Yuchang;
Chen, Hongli;
Feng, Jun

Publication type:

Article

Inhibition of JMJD6 by 2‐Oxoglutarate Mimics.

Published in:

ChemMedChem, 2022, v. 17, n. 1, p. 1, doi. 10.1002/cmdc.202100398

By:

Islam, Md. Sailful;
Thinnes, Cyrille C.;
Holt‐Martyn, James P.;
Chowdhury, Rasheduzzaman;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.

Published in:

ChemMedChem, 2021, v. 16, n. 13, p. 2082, doi. 10.1002/cmdc.202100133

By:

Figg, William D.;
McDonough, Michael A.;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Zhang, Zhihong;
Holt‐Martyn, James P.;
Krajnc, Alen;
Schofield, Christopher J.

Publication type:

Article

Structure‐Activity Relationship and Crystallographic Studies on 4‐Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors.

Published in:

ChemMedChem, 2020, v. 15, n. 3, p. 270, doi. 10.1002/cmdc.201900557

By:

Holt‐Martyn, James P.;
Chowdhury, Rasheduzzaman;
Tumber, Anthony;
Yeh, Tzu‐Lan;
Abboud, Martine I.;
Lippl, Kerstin;
Lohans, Christopher T.;
Langley, Gareth W.;
Figg, William;
McDonough, Michael A.;
Pugh, Christopher W.;
Ratcliffe, Peter J.;
Schofield, Christopher J.

Publication type:

Article

ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site.

Published in:

ChemMedChem, 2008, v. 3, n. 4, p. 569, doi. 10.1002/cmdc.200700233

By:

Mecinović, Jasmin;
Chowdhury, Rasheduzzaman;
Liénard, Benoît M. R.;
Flashman, Emily;
Buck, Matthew R. G.;
Oldham, Neil J.;
Schofield, Christopher J.

Publication type:

Article

Cover Picture: ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site (ChemMedChem 4/2008).

Published in:

ChemMedChem, 2008, v. 3, n. 4, p. 509, doi. 10.1002/cmdc.200890014

By:

Mecinović, Jasmin;
Chowdhury, Rasheduzzaman;
Liénard, Benoît M. R.;
Flashman, Emily;
Buck, Matthew R. G.;
Oldham, Neil J.;
Schofield, Christopher J.

Publication type:

Article

Substrate Selectivity Analyses of Factor Inhibiting Hypoxia-Inducible Factor.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 6, p. 1700, doi. 10.1002/anie.201208046

By:

Yang, Ming;
Hardy, Adam P.;
Chowdhury, Rasheduzzaman;
Loik, Nikita D.;
Scotti, John S.;
McCullagh, James S. O.;
Claridge, Timothy D. W.;
McDonough, Michael A.;
Ge, Wei;
Schofield, Christopher J.

Publication type:

Article

Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 27, p. 6672, doi. 10.1002/anie.201202000

By:

Demetriades, Marina;
Leung, Ivanhoe K. H.;
Chowdhury, Rasheduzzaman;
Chan, Mun Chiang;
McDonough, Michael A.;
Yeoh, Kar Kheng;
Tian, Ya-Min;
Claridge, Timothy D. W.;
Ratcliffe, Peter J.;
Woon, Esther C. Y.;
Schofield, Christopher J.

Publication type:

Article

Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates.

Published in:

Epigenetics, 2014, v. 9, n. 12, p. 1596, doi. 10.4161/15592294.2014.983381

By:

Williams, Sophie T;
Walport, Louise J;
Hopkinson, Richard J;
Madden, Sarah K;
Chowdhury, Rasheduzzaman;
Schofield, Christopher J;
Kawamura, Akane

Publication type:

Article

Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2.

Published in:

Proteins, 2023, v. 91, n. 11, p. 1510, doi. 10.1002/prot.26541

By:

Figg, William D.;
Fiorini, Giorgia;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Tumber, Anthony;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway.

Published in:

Proteins, 2010, v. 78, n. 6, p. 1398, doi. 10.1002/prot.22653

By:

Iqbal, Aman;
Arunlanantham, Haren;
Brown, Tom;
Chowdhury, Rasheduzzaman;
Clifton, Ian J.;
Kershaw, Nadia J.;
Hewitson, Kirsty S.;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article